International Research Journal of Pharmaceutical and Applied Sciences最新文献

Attitudes amongst Saudi hospital paramedics toward seasonal Influenza and Vaccination 沙特医院护理人员对季节性流感和疫苗接种的态度

International Research Journal of Pharmaceutical and Applied Sciences Pub Date : 2021-02-26 DOI: 10.26452/IRJPAS.V11I1.1398

Hany Hosny, Samiha Fawzy, Tarek M. Esmael, O. Rashed, T. A. Anazi, Arulanantham Zechariah Jebakumar

{"title":"Attitudes amongst Saudi hospital paramedics toward seasonal Influenza and Vaccination","authors":"Hany Hosny, Samiha Fawzy, Tarek M. Esmael, O. Rashed, T. A. Anazi, Arulanantham Zechariah Jebakumar","doi":"10.26452/IRJPAS.V11I1.1398","DOIUrl":"https://doi.org/10.26452/IRJPAS.V11I1.1398","url":null,"abstract":"Paramedics were only given the essentials to deal with influenza vaccination. On the other hand, 67.6 percent of them were actually vaccinated. To reduce the spread of the virus, healthcare providers should work hard to immunize the population around us at any given time. There has been a lot of study into flu, and the general consensus is that it is a type of acute respiratory illness. Influenza is a very contagious and transmissible viral disease that can cause very severe symptoms. This was designed to determine those parents who smoke, how aware they are about the flu symptoms, and how they deal with them. This survey is a part of a study that was conducted by us of healthy male paramedics. When they were given an online questionnaire that included eight questions, all the participants found the questions to be very straightforward. As a result of this survey, we will know exactly what the Saudi parents really know about disease prevention and treatments. The purpose of the study is to find out if the paramedics of Saudi Hospitals would like to be vaccinated against seasonal influenza. The paper uses the word \"seriously\" to talk about the importance of vaccination (which is an interesting word choice). This research was conducted on a sample of 222 healthy male paramedics assessed by the use of an online questionnaire, along with a personal rating of beliefs regarding influenza vaccination and the status of self-reported vaccination. The paper also identifies the reasons why the people in question are not being vaccinated and the outcomes. By conducting a percentage analysis by reviewing the questionnaire results, it was found that the paramedics were very unaware of the importance of and effectiveness of the Hepatitis B Vaccination. According to what the paramedics found, the vaccine wasn't available in the hospitals, so they couldn't administer it, either.","PeriodicalId":340190,"journal":{"name":"International Research Journal of Pharmaceutical and Applied Sciences","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131859813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrosion resistance studies of aluminium 7075 / SiC composites materials in an acidic environment 铝7075 / SiC复合材料在酸性环境中的耐腐蚀性能研究

International Research Journal of Pharmaceutical and Applied Sciences Pub Date : 2020-12-28 DOI: 10.26452/irjpas.v10i4.1388

Manoharan E K, Singanan M

{"title":"Corrosion resistance studies of aluminium 7075 / SiC composites materials in an acidic environment","authors":"Manoharan E K, Singanan M","doi":"10.26452/irjpas.v10i4.1388","DOIUrl":"https://doi.org/10.26452/irjpas.v10i4.1388","url":null,"abstract":"The aluminium and silicon carbide-based composite (Al-SiC) material was prepared using commercially available analytical grade Al7075 alloy and SiC. Here the silicon carbide is used as reinforcement particles in the composites. The metal composites were developed using liquid melt techniques (Vortex method). The reinforcement material is introduced in different weight fractions in the range of 0 to 10% in this process. These Al-SiC specimens were used for assessment of its corrosion properties. The acid corrosion experiments were carried out at room temperature (30 ±1oC). The corrosion characteristics were estimated using the conventional weight loss method according to the procedure of ASTM G69-80. The composites performance was evaluated using microstructural analysis and the corrosion resistance tendency in different acidic environmental conditions. The SEM micrographs picture reveals that reinforcement particle was distributed uniformly. The corrosion test was conducted in HCl medium from 0.25N, 0.5N, 1M and 1.5 M respectively. The Al-SiC specimens were dipped in different HCl medium for four days in six experimental baths. Specimens were taken out from each test medium for every 24 hours and tested for its corrosion characteristics. It is observed that the corrosion rate in all HCl medium decreases with an increase in exposure time. This is due to the passivation of the Al-SiC surface induced by aluminium. It was observed that at the 10 w/w % of the aluminium metal matrix composite have higher corrosion resistance than the base alloy.","PeriodicalId":340190,"journal":{"name":"International Research Journal of Pharmaceutical and Applied Sciences","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132197649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An ayurvedic tablet formulation for ulcer protection 一种用于溃疡保护的阿育吠陀片剂配方

International Research Journal of Pharmaceutical and Applied Sciences Pub Date : 2020-12-11 DOI: 10.26452/irjpas.v10i4.1374

K. Shivakumar, M. Purushothaman, H. Soujanya, S. Jagadeeshwari

{"title":"An ayurvedic tablet formulation for ulcer protection","authors":"K. Shivakumar, M. Purushothaman, H. Soujanya, S. Jagadeeshwari","doi":"10.26452/irjpas.v10i4.1374","DOIUrl":"https://doi.org/10.26452/irjpas.v10i4.1374","url":null,"abstract":"Gastric ulcers or the peptic ulcer is the primary disease that affects the gastrointestinal system. A large extent of the population in the world are suffering from the disease, and the age group of people those who suffer from ulcers are 20-55years. Herbs are known to the human beings that are useful in the treatment of diseases, and there are a lot of scientific investigations that prove the pharmacological activity of herbal drugs. Practitioners have been using the herbal material to treat the ulcers successfully, and the same had been reported scientifically. Numerous publications have been made that proves the antiulcer activity of the plants around the world. The tablets were investigated for the antiulcer activity in two doses 200 and 400mg/kg in albino Wistar rats in the artificial ulcer those are induced by the ethanol. The prepared tablets showed a better activity compared to the standard synthetic drug and the marketed ayurvedic formulation. The tablets showed a dose-dependent activity in ulcer prevention and treatment. Many synthetic drugs are available for the ulcer treatment, and the drugs pose the other problems in the body by showing the side effects and some other reactions. This limits the use of synthetic drugs to treat ulcers effectively. Herbs are known to the human beings that are useful in the treatment of diseases, and there are a lot of scientific investigations that prove the pharmacological activity of herbal drugs.","PeriodicalId":340190,"journal":{"name":"International Research Journal of Pharmaceutical and Applied Sciences","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127553050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In-vivo anti-oxidant screening of Tectona grandis extract 大地构造提取物的体内抗氧化筛选

International Research Journal of Pharmaceutical and Applied Sciences Pub Date : 2020-06-26 DOI: 10.26452/irjpas.v9i1.1164

P. TamilarasiG, G. Sabarees

引用次数: 0

A Study for dexmedetomidine for Fibreoptic intubation 右美托咪定用于纤维插管的研究

International Research Journal of Pharmaceutical and Applied Sciences Pub Date : 2019-12-28 DOI: 10.26452/irjpas.v9i4.1348

S. Seshaiah, J. Chandrudu, R. Sagar, M. Madhubushan

{"title":"A Study for dexmedetomidine for Fibreoptic intubation","authors":"S. Seshaiah, J. Chandrudu, R. Sagar, M. Madhubushan","doi":"10.26452/irjpas.v9i4.1348","DOIUrl":"https://doi.org/10.26452/irjpas.v9i4.1348","url":null,"abstract":"Trauma is a major fitness hassle of modern-day society and maxillofacial injuries because of high-pace trauma from avenue visitors accidents, sports activities accidents or falls require airway renovation with cervical spine stabilisation and manage of bleeding along a unique set of problems.Compromised airway is lifestyles-threatening both within the early and later levels leading to hypoxia or obstruction. Awake fibreoptic bronchoscope (FOB)-guided endotracheal intubation (AFOI) is an powerful method for coping with patients with tough airway, and is presently taken into consideration the gold standard(eleven). Dexmedetomidine at a dose of 0.75 mcg/kg and 1.0 mcg/kg over 20 mins turned into drastically found to be powerful in maintaining sufferers comfy at some point of Awake fibre optic intubation. While 0.5 mcg/kg of loading dose had strong haemodynamics and did no longer have any adverse occasions, 1 mcg/kg of loading dose precipitated high blood pressure in 2 sufferers and 0.75 mcg/kg of loading dose triggered cardiac rhythm abnormality (ventricular ectopics) in one patient. Dexmedetomidine at a loading dose of 0.5 mcg/kg is secure, whereas loading doses of zero.75 mcg/kg and 1 mcg/kg gives better patient consolation. More quantity of research ought to be finished the use of a packing dose of 0.75 mcg/kg to set up its protection.","PeriodicalId":340190,"journal":{"name":"International Research Journal of Pharmaceutical and Applied Sciences","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132462377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel Sources of Drug Components in Plants 植物药物成分的新来源

International Research Journal of Pharmaceutical and Applied Sciences Pub Date : 2018-06-28 DOI: 10.26452/irjpas.v8i3.1317

Sagar R., Madhubhushan M, Seshaiah S, Chandrudu J

{"title":"Novel Sources of Drug Components in Plants","authors":"Sagar R., Madhubhushan M, Seshaiah S, Chandrudu J","doi":"10.26452/irjpas.v8i3.1317","DOIUrl":"https://doi.org/10.26452/irjpas.v8i3.1317","url":null,"abstract":"This survey is a refreshed and extended adaptation of a paper that was distributed in this diary in 1997. The time span has been reached out in the two headings to incorporate the 22 years from 1981 to 2002, and another optional development identified with the normal item source yet applied to officially engineered mixes has been presented, utilizing the idea of a \"characteristic item copy\" or \"NM\" to join the first essential separations. From the information introduced, the utility of characteristic items as wellsprings of novel structures, however not the last medication substance, is as yet perfectly healthy. In this way, in the region of malignant growth, the level of the little atom, new compound substances that are nonsynthetic has stayed at 62% found the median value of over the entire time. In different territories, the impact of characteristic item structures is very stamped, especially in the antihypertensive region, of which the 74 officially engineered drugs, 48 can be followed to standard item structures/copies. Correspondingly, with the 10 antimigraine drugs, seven depend on the serotonin atom or subsidiaries thereof.","PeriodicalId":340190,"journal":{"name":"International Research Journal of Pharmaceutical and Applied Sciences","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116150693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The treatment of cancer by influenced of alpha and beta momorcharin -和-苦瓜素的作用治疗癌症

International Research Journal of Pharmaceutical and Applied Sciences Pub Date : 2018-06-16 DOI: 10.26452/irjpas.v8i4.1324

Sravan Kumar P, Akila CR, Vinaya B, Dinesh Babu J

{"title":"The treatment of cancer by influenced of alpha and beta momorcharin","authors":"Sravan Kumar P, Akila CR, Vinaya B, Dinesh Babu J","doi":"10.26452/irjpas.v8i4.1324","DOIUrl":"https://doi.org/10.26452/irjpas.v8i4.1324","url":null,"abstract":"A huge number of plant had been utilized quite for the cure of malignant growths all through the segment. The protein, β ,α, momorcharin has been removed from the plant Momordica charantia (MC), and it has threatening to most dangerous developments and against HIV properties like the foul aquatic and methanol dissolvable concentrate of the plant. This assessment investigated the counter threatening development impacts and the telephone frameworks of advancement of α, β momocharin (200 800 μM) on 1321N1, Gos-three, U87-MG, Sk Mel, Corl-23 and Weri Rb-1 most illnesses convenient strains when appeared differently in relation to normal solid L6 muscle cell line evaluating flexible achievability the usage of MTT measure group, Caspase-three and 9 games, cytochrome c release and intracellular free calcium obsessions [Ca(2+)]i. The results show that α, β momorcharin can bring huge part subordinate (P < zero.05; Student's t examine) reduces in the appropriateness (increases in cell loss of life) of 1321N1, Gos-3, U87-MG, Sk Mel, Corl-23 and Weri Rb-1 harmful development cell follows when appeared differently in relation to solid L6 muscle cell line and untreated glioma cells. α, β momorcharin (800 μM) additionally evoked extraordinary evaluated (P < zero.05) will increase in caspase-three and nine activities and cytochrome c dispatch. Along these lines, α, β momorcharin evoked gigantic (P < 0.05) time-subordinate tallness in [Ca(2+)]i in all of the 5 glioma cell strains conversely with untreated cells. Together, the results have attempted that α, β momorcharin can apply its enemy of malignancy impact on elite disease cell lines by means of intracellular procedures identified with an affront to the mitochondria bringing about cell calcium over stacking, apoptosis, cytochrome discharge and at long last, cell death toll.","PeriodicalId":340190,"journal":{"name":"International Research Journal of Pharmaceutical and Applied Sciences","volume":"107 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124161147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research on Electrotransfection Treatment Against Nonviral Method 电转染治疗非病毒方法的研究

International Research Journal of Pharmaceutical and Applied Sciences Pub Date : 2018-06-10 DOI: 10.26452/irjpas.v8i3.1316

Chandrudu J, Sagar R., Madhubhushan M, Seshaiah S

{"title":"Research on Electrotransfection Treatment Against Nonviral Method","authors":"Chandrudu J, Sagar R., Madhubhushan M, Seshaiah S","doi":"10.26452/irjpas.v8i3.1316","DOIUrl":"https://doi.org/10.26452/irjpas.v8i3.1316","url":null,"abstract":"Electrotransfection (ET) may be a nonverbal strategy for movement of varied varieties of particles into cells each in vivo and in vitro. Near to ninety clinical fundamentals that incorporate the usage of ET are achieved, and usually 1/2 them area unit associated with dangerous development treatment. Notably, ET may be a charming system for dangerous development immunogene treatment since the treatment of cell with electrical pulses alone will have an effect on safe replies to solid tumours, and also the reactions is furthermore updated by ET of inclusion DNA (pDNA) coding therapeutic characteristics. Appeared otherwise in relevance to different quality transport techniques, ET contains several exceptional central focuses. It's tolerably smart, versatile, and harmless in clinical applications, and brings merely exposed pDNA into cells while not the usage of extra factory-made mixes or diseases. In any case, the potential of ET continues to be low, not utterly in lightweight of the fact that natural frameworks of ET in cells stay difficult. In past assessments, it had been acknowledged that pDNA arrived the cell through fleeting apertures shaped by electrical pulses. Consequently, the strategy is generally silent as electroporation. Regardless, continuous revelations have steered that endocytosis expect a stimulating activity in cell take-up and intracellular vehicle of electro transfected pDNA. This summary can deliberate stream progress within the examination of characteristic frameworks essential ET and future direction of assessment around there. Sympathetic the components of pDNA transport in the cell is crucial for the expansion of recent procedures for up the profitableness significant movement in tumours.","PeriodicalId":340190,"journal":{"name":"International Research Journal of Pharmaceutical and Applied Sciences","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130052908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0