G. Murphy, A. Naughton, R. Murphy, C. McCaughey, A. Maree
{"title":"13 A CT coronary angiography first strategy in patients determined to have an indication for invasive coronary angiogram: a meta-analysis","authors":"G. Murphy, A. Naughton, R. Murphy, C. McCaughey, A. Maree","doi":"10.1136/heartjnl-2022-ics.13","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-ics.13","url":null,"abstract":"","PeriodicalId":329496,"journal":{"name":"Oral abstract presentations 2","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133822170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Brandon, R. Armstrong, B. Kerr, C. Finucane, M. Afonso Shirsath, M. Hensey, S. O’Connor, Rachel Kenny, A. Maree
{"title":"17 Heart rate recovery following active stand test in patients with versus without severe aortic stenosis","authors":"L. Brandon, R. Armstrong, B. Kerr, C. Finucane, M. Afonso Shirsath, M. Hensey, S. O’Connor, Rachel Kenny, A. Maree","doi":"10.1136/heartjnl-2022-ics.17","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-ics.17","url":null,"abstract":"","PeriodicalId":329496,"journal":{"name":"Oral abstract presentations 2","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127226405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. McInerney, J. Rodés‐Cabau, G. Veiga, D. López‐Otero, E. Muñoz-García, F. Campelo, J. Oteo, M. Carnero, JD Tafur Soto, I. Amat-Santos, A. Travieso, S. Mohammadi, M. Barbanti, A. Cheema, S. Toggweiler, F. Saia, M. Dąbrowski, V. Serra, F. Alfonso, H. Barbosa, A. Regueiro, A. Alperi, AG Ongay, JM Martinez Cereijo, A. Muñoz-Garcia, A. Matta, C. Arellano-Serrano, A. Barrero, G. Tirado-Conte, N. Gonzalo, XC Sanmartin, J. M. de la Torre Hernández, D. Kalavrouziotis, L. Maroto, A. Forteza-Gil, J. Cobiella, J. Escaned, L. Nombela-Franco
{"title":"14 Morbidly obese patients with symptomatic severe aortic stenosis, what is the optimal treatment strategy? A propensity score matched analysis of transcatheter versus surgical aortic valve replacement","authors":"A. McInerney, J. Rodés‐Cabau, G. Veiga, D. López‐Otero, E. Muñoz-García, F. Campelo, J. Oteo, M. Carnero, JD Tafur Soto, I. Amat-Santos, A. Travieso, S. Mohammadi, M. Barbanti, A. Cheema, S. Toggweiler, F. Saia, M. Dąbrowski, V. Serra, F. Alfonso, H. Barbosa, A. Regueiro, A. Alperi, AG Ongay, JM Martinez Cereijo, A. Muñoz-Garcia, A. Matta, C. Arellano-Serrano, A. Barrero, G. Tirado-Conte, N. Gonzalo, XC Sanmartin, J. M. de la Torre Hernández, D. Kalavrouziotis, L. Maroto, A. Forteza-Gil, J. Cobiella, J. Escaned, L. Nombela-Franco","doi":"10.1136/heartjnl-2022-ics.14","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-ics.14","url":null,"abstract":"","PeriodicalId":329496,"journal":{"name":"Oral abstract presentations 2","volume":"179 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124457581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Radhakrishna, A. Brennan, B. Wong, M. Ledwidge, K. McDonald
{"title":"16 The effects of nocturnal blood pressure dipping pattern on cardiac structure assessed using transthoracic echocardiography (TTE) and cardiovascular magnetic resonance (CMR)","authors":"A. Radhakrishna, A. Brennan, B. Wong, M. Ledwidge, K. McDonald","doi":"10.1136/heartjnl-2022-ics.16","DOIUrl":"https://doi.org/10.1136/heartjnl-2022-ics.16","url":null,"abstract":"","PeriodicalId":329496,"journal":{"name":"Oral abstract presentations 2","volume":"09 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122876253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Giacoppo, Fernando Alfonso, Adnan Kastrati, R. A. Byrne
{"title":"15 Drug-coated balloon angioplasty versus drug-eluting stent implantation for the treatment of bare-metal and drug-eluting stent restenosis: results from the daedalus study","authors":"D. Giacoppo, Fernando Alfonso, Adnan Kastrati, R. A. Byrne","doi":"10.1136/HEARTJNL-2020-ICS.15","DOIUrl":"https://doi.org/10.1136/HEARTJNL-2020-ICS.15","url":null,"abstract":"Background In patients with coronary in-stent restenosis (ISR) requiring re-intervention, it is unclear if the choice of treatment strategy depends on whether the restenotic stent was a bare-metal stent (BMS) or a drug-eluting stent (DES). Objectives We aimed to assess the comparative efficacy and safety of the two most frequently used treatments – angioplasty with drug-coated balloon (DCB) and repeat stenting DES – in patients with BMS- and DES-ISR. Methods The DAEDALUS study was a pooled analysis of individual patient data from all 10 existing randomized clinical trials comparing DCB angioplasty vs. repeat DES implantation for the treatment of coronary ISR. In this prespecified analysis, patients were stratified according to BMS- vs. DES-ISR, and treatment assigned. The primary efficacy endpoint was target lesion revascularization (TLR) at 3 years. The primary safety endpoint was a composite of all-cause death, myocardial infarction, or target lesion thrombosis at 3 years. Primary analysis was performed by Cox mixed-effects models accounting for the trial of origin. Secondary analyses included non-parsimonious multivariable adjustment accounting also for multiple lesions per patient and two-stage analyses. Results A total of 710 patients with BMS-ISR (722 lesions) and 1248 with DES-ISR (1377 lesions) were included. In patients with BMS-ISR, no significant difference between treatments was observed in terms of primary efficacy (9.2% vs. 10.2%; HR 0.83, 95% CI 0.51–1.37) and safety endpoints (8.7% vs. 7.5%; HR 1.13, 95% CI 0.65–1.96); results of secondary analyses were consistent. In patients with DES-ISR, the risk of the primary efficacy endpoint was higher with DCB angioplasty compared with repeat DES implantation (20.3% vs. 13.4%; HR 1.58, 95% CI 1.16–2.13), while the risk of the primary safety endpoint was only numerically lower (9.5% vs. 13.3%; HR 0.69, 95% CI 0.47–1.00) and interaction was not significant (p=0.146); results of secondary analyses were consistent. The risk of TLR was lower in BMS- vs. DES-ISR (9.7% vs. 17.0%; HR 0.57, 95% CI 0.42–0.74), while safety was not significantly different between ISR types. Conclusions At 3-year follow-up, DCB angioplasty and repeat stenting with DES are similarly effective and safe in the treatment of BMS-ISR, while DCB angioplasty is significantly less effective than repeat DES implantation in the treatment DES-ISR without statistically significant differences in safety endpoints. Overall, DES-ISR is associated with higher rates of treatment failure and similar safety compared with BMS-ISR.","PeriodicalId":329496,"journal":{"name":"Oral abstract presentations 2","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114347336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}