Radiation Oncology [Working Title]最新文献

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Photodynamic Therapy in Complex Therapy of Retroperitoneal Tumors in Children 光动力疗法在儿童腹膜后肿瘤综合治疗中的应用

Radiation Oncology [Working Title] Pub Date : 2022-01-21 DOI: 10.5772/intechopen.101884

N. Rostovtsev, V. Polyakov, N. Kuzmina

{"title":"Photodynamic Therapy in Complex Therapy of Retroperitoneal Tumors in Children","authors":"N. Rostovtsev, V. Polyakov, N. Kuzmina","doi":"10.5772/intechopen.101884","DOIUrl":"https://doi.org/10.5772/intechopen.101884","url":null,"abstract":"During the period from 2009 to 2021, 93 patients aged 0–11 years (48 boys and 45 girls) with retroperitoneal tumors were treated. There were 66 patients with nephroblastoma and 27 patients with adrenal neuroblastoma among them. As per treatment strategies, the patients were separated into two groups: the control group and the study group. The control group (comparison) received therapy according to the protocols, whereas the study group consisted of patients who received photodynamic therapy (PDT) in addition to the standard treatment. The control group consists of 47 patients with retroperitoneal tumors, including 35 patients with nephroblastoma and 12 patients with adrenal neuroblastoma. The study group included 46 children: 31 patients with nephroblastoma and 15 patients with adrenal neuroblastoma. The 5-year survival rate in the control group was 74.5%, and it was 91.3% in the study group (p = 0.030). Recurrent tumors developed in 14.9% of the patients in the control group, while in the study group, relapse occurred in 8.7% of the patients (p = 0.357). The PDT used in this study for treatment of retroperitoneal tumors improves the results of surgical treatment. It also appreciably increases the survival rate of patients with retroperitoneal tumors. Overall, PDT is a hopeful antitumor approach and can be effectively used in the complex therapy of retroperitoneal tumors in children.","PeriodicalId":328893,"journal":{"name":"Radiation Oncology [Working Title]","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116228620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dosimetry Audit in Modern Radiotherapy 现代放射治疗中的剂量学审核

Radiation Oncology [Working Title] Pub Date : 2021-12-17 DOI: 10.5772/intechopen.100941

Katia Manolova Sergieva

{"title":"Dosimetry Audit in Modern Radiotherapy","authors":"Katia Manolova Sergieva","doi":"10.5772/intechopen.100941","DOIUrl":"https://doi.org/10.5772/intechopen.100941","url":null,"abstract":"The clinical specialty of radiotherapy is an essential part of the multidisciplinary process of treatment of malignant neoplasms. Modern radiotherapy is a very complex process of treatment planning and delivery of radiation dose. Radiotherapy reached a very high degree of complexity and sophistication and expected to represent an added value for the cancer patients in terms of clinical outcomes and improved radiation protection. The concept of verifying the realized dose in the medical applications of ionizing radiation was introduced in the early 20th century shortly after the first application of X-rays for the treatment of cancer. Dosimetry audit identify areas for improvement and provide confidence in safety and efficacy, which are essential to creating a clinical environment of continuous development and improvement. Over the years, the audits have contributed to good dosimetry practice and accuracy of dose measurements in modern radiotherapy. Dosimetry audit ensures, that the correct therapeutic dose is delivered to the patients undergoing radiotherapy and play a key role in activities to create a good radiation protection and safety culture. Patient safety is of paramount importance to medical staff in radiotherapy centers and safety considerations are an element in all aspects of the day-to-day clinical activities.","PeriodicalId":328893,"journal":{"name":"Radiation Oncology [Working Title]","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122062206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment Practices in Optic Nerve Glioma 视神经胶质瘤的治疗实践

Radiation Oncology [Working Title] Pub Date : 2021-11-13 DOI: 10.5772/intechopen.101054

Rashmi Singh, Anup Kumar, P. Raina, R. Tudu, Praveer K.S. Munda

引用次数: 0