Endoprosthetic Total Scapula Replacement Versus Suspension Arthroplasty Following Tumor Resection最新文献

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Role of the complete pathological response in rectal cancer: Value as a prognostic factor 完全病理反应在直肠癌中的作用:作为预后因素的价值

Endoprosthetic Total Scapula Replacement Versus Suspension Arthroplasty Following Tumor Resection Pub Date : 2019-01-10 DOI: 10.31487/J.JSO.2018.01.005

G. R. Caravaca, Ignacio Juez-Martel, Ma Victoria De-Torres-Olombrada, M. Durán-Poveda

{"title":"Role of the complete pathological response in rectal cancer: Value as a prognostic factor","authors":"G. R. Caravaca, Ignacio Juez-Martel, Ma Victoria De-Torres-Olombrada, M. Durán-Poveda","doi":"10.31487/J.JSO.2018.01.005","DOIUrl":"https://doi.org/10.31487/J.JSO.2018.01.005","url":null,"abstract":"Objective \u0000To study the effect of the pathologic complete response (pCR) on the survival of patients treated with \u0000surgery and neoadjuvant chemo-radiotherapy in locally advanced non-metastatic rectal carcinoma (LARC). \u0000Materials and methodology \u0000We underwent an observational retrospective analysis of cohorts. The recruitment was carried out by means \u0000of non-probabilistic consecutive inclusion of patients with rectal cancer treated between January 2009 and \u0000December 2016 with surgery and neoadjuvant chemo-radiotherapy. The patients recruited had been \u0000diagnosed with locally advanced non-metastatic rectal cancer. cT3-4 o N+. based on the American Joint \u0000Committee on Cancer (AJCC) 2010. with histological confirmation of adenocarcinoma and no treatment \u0000with induction chemotherapy. The pathologic response was calibrated in accordance with the Ryan system. \u0000Survival was calculated with multivariate Cox regression analysis \u0000Results \u0000Pathologic complete response was reached by 19.2% Patients. The disease free survival was significantly \u0000lower in the no pathologic complete response (HR 0.099. p value 0.025). The progression in the group of \u0000patients with pathological complete response occurred in only one patient and have local and distal \u0000component compared to 39 patients in no pCR 21.2% distant metastases and 3.8% locally relapse. \u0000Perineural invasion and adjuvant chemotherapy were also significatly associated with disease free survival \u0000Conclusions \u0000The pathological complete response is a good prognosis factor in patients treated with surgery and nCRT \u0000in LARC with distal and local relapse. Perineural invasion and adjuvant chemotherapy were also good \u0000prognostic factors.","PeriodicalId":320469,"journal":{"name":"Endoprosthetic Total Scapula Replacement Versus Suspension Arthroplasty Following Tumor Resection","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125349680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Biomechanical Study of Simulated Metastatic Peri-Acetabular Defects 模拟转移性髋臼周围缺损的生物力学研究

Endoprosthetic Total Scapula Replacement Versus Suspension Arthroplasty Following Tumor Resection Pub Date : 2018-12-29 DOI: 10.31487/J.JSO.2018.01.003

F. Patterson, J. Thomson, J. Benevenia, Kathleen S Beebe, Michael N. Kang

引用次数: 0