AlQadisiyah Journal for Engineering Science最新文献

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AlQadisiyah Journal for Engineering Science Pub Date : 2023-06-26 DOI: 10.30772/qjes/qjes.2023.141345.1000
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引用次数: 0
The association between iron over load and tanner stage retardation in the females with B-thalassemia major in Thalassemia center of Diwaniyah maternity and children teaching Hospital. 迪瓦尼耶妇幼教学医院地中海贫血中心女性b型地中海贫血患者铁负荷与鞣革期发育迟缓的关系
AlQadisiyah Journal for Engineering Science Pub Date : 2022-06-30 DOI: 10.28922/qmj.2022.18.1.10-18
Suzan Sabbar Mutlag
{"title":"The association between iron over load and tanner stage retardation in the females with B-thalassemia major in Thalassemia center of Diwaniyah maternity and children teaching Hospital.","authors":"Suzan Sabbar Mutlag","doi":"10.28922/qmj.2022.18.1.10-18","DOIUrl":"https://doi.org/10.28922/qmj.2022.18.1.10-18","url":null,"abstract":"Despite optimal therapy of patients with B- thalassemia major included regular blood transfusion program and iron chalation agents helped by increasing survival of these patients but remained major problem in adolescent of these patients such as growth failure and hypogonadisim. 
 Aim of study: To determine the association between iron over load and tanner stage retardation among female patients with B- thalassemia major in Thalassemia center of Diwaniyah maternity and children teaching Hospital.
 Methods: The current study was carried out on all female patients diagnosed ?-thalassemia major on the base of the blood investigations (peripheral blood counts and hemoglobin electrophoresis),with their age range from 13years to 16 years who registered in Thalassemia center of Diwaniyah maternity and children teaching hospital in Al- Diwaniyah Governorate, Republic of Iraq. The Data collection was carried out during the period from the 1st of April of 2016 to 30th of December of 2016. They were studied for determining the association between iron over load and tanner stage retardation among female patients with B- thalassemia major.
 The following data were collected from the patients: 
 Name, age, address ,age of diagnosis of thalassemia, number of blood transfusion per year, types of chelating agent.
 In the physical examination, the patients were assessed for weight, height, Tanner stages and body mass index(BMI) which recorded.
 
 Ferritin value was used to assess iron load, pelvic ultrasound was checked to assess the size of uterus and both ovaries.
 
 Results: Total numbers of B- thalassemia major female patients are 31 patient, aged 13-16 years (mean age: 14.13 ±1.20) . Age of patients at time of diagnosis of B- thalassemia major range from 0.17 to 5 year with Mean ± SD(1.40 ±1.30). Frequency of Blood transfusion (time/Year) range from 6 to 33 time/Year with Mean ± SD(16.68 ±4.98). Level of serum ferritin of the patients was ranged from 913-12000 ng/ml with Mean ± SD (4963.60 ±3580.39).
 Tanner stage I was predominant accounting for 87% whereas stage II and III accounted for 10% and 3% respectively. There was no significant correlation between Tanner stage and age of patient and also no significant correlation with age at time of diagnosis (P>0.05). There was a significant negative correlation between frequency of blood transfusion and Tanner (r=-0.385, P= 0.045), so that the higher the frequency of transfusion, the lower the tanner stage is. No correlation was found between the dose of chelating agent and Tanner stage (P=0.599). Height and weight of patients were significantly correlated with Tanner stage (P=0.028 and P=0.007, respectively). No significant correlation was found between serum ferritin and Tanner stage (P=0.444). There was a significant correlation between Uterus size, ovarian size and Tanner stage (P=0.007and P=0.007, respectively).
 Conclusion: These results showed that ","PeriodicalId":30984,"journal":{"name":"AlQadisiyah Journal for Engineering Science","volume":"18 1","pages":"10-18"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://qmj.qu.edu.iq/index.php/QMJ/article/download/848/640","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147882008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The liver injury in patients with B-thalassemia major secondary to iron over load in Thalassemia center of Diwaniyah maternity and children teaching Hospital . A clinical study in Thalassemia center of Diwaniyah maternity and children teaching Hospital 迪瓦尼耶妇幼教学医院地中海贫血中心继发铁负荷过重的乙型地中海贫血患者肝损伤。迪瓦尼耶妇幼教学医院地中海贫血中心的临床研究
AlQadisiyah Journal for Engineering Science Pub Date : 2018-12-05 DOI: 10.28922/qmj.2017.13.24.39-45
Suzan Sabber Mutlag
{"title":"The liver injury in patients with B-thalassemia major secondary to iron over load in Thalassemia center of Diwaniyah maternity and children teaching Hospital . A clinical study in Thalassemia center of Diwaniyah maternity and children teaching Hospital","authors":"Suzan Sabber Mutlag","doi":"10.28922/qmj.2017.13.24.39-45","DOIUrl":"https://doi.org/10.28922/qmj.2017.13.24.39-45","url":null,"abstract":"Background:liver iron concentration assessed by MRI T2* is the better indicator of total-body iron depositions and should be checked in frequent blood transfused patients. MRI T2* can be detect iron overload before iron toxicity becomes clinically apparent.Aim of study: to prevalence of liver injury among patients with B- thalassemia major secondary to iron over load in Thalassemia center of Diwaniyah maternity and children teaching Hospital.Methods: This a cross – sectional study was carried out on 58 patients (34 males and 24 females ) diagnosed ?-thalassemia major on the base of the blood investigations (peripheral blood counts and hemoglobin electrophoresis), their age range from 9 years to 36 years. The study was conducted in Thalassemia center of Diwaniyah maternity and children teaching hospital in Al- Diwaniyah Governorate, Republic of Iraq. The Data collection was carried out during the period from the 30th of December 2015 to 11th of August 2016. They were studied for prevalence of liver injury among patients with thalassemia major secondary to iron over load. Results: Total numbers of B- thalassemia major patients are 58 patient. The numbers of patients with ages less than 10 years are 3 (5.2%), patients with ages(10-18)years are 39 (67.2%), patients with ages(19-25)years are 12(20.7%). statistically significant correlation was found between liver function test (LFT) abnormality ( ALT, AST) and numbers of blood transfusion per year (P=0.001) and also LFT abnormality ( ALT, AST) and ferritin levels (P=0.01). In our study reported that liver iron concentration was presented normal in 23 patients (39.7%), mild iron concentration in 29 patients (50.0%) and moderate iron concentration in 6 patients (10.3%). There was a significant association between serum ferritin level and the liver iron concentration assess by liver MRI T2* (P=0.002).Conclusion: These results showed that correlation between ferritin, LFT abnormality and liver iron storage detected by MRI T2 in patients with ?-thalassemia major. MRI T2* has become the clinical standard to estimate liver iron overload.","PeriodicalId":30984,"journal":{"name":"AlQadisiyah Journal for Engineering Science","volume":"13 24","pages":"39-45"},"PeriodicalIF":0.0,"publicationDate":"2018-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://qmj.qu.edu.iq/index.php/QMJ/article/download/672/561","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147919720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of Extended Spectrum Beta Lactamase (ESBL) in Klebseilla pneumoniae Isolated from Urinary Tract Infections 尿路感染肺炎克雷伯菌扩展谱β -内酰胺酶(ESBL)的检测
AlQadisiyah Journal for Engineering Science Pub Date : 2017-07-26 DOI: 10.28922/qmj.2014.10.18.168-173
Ibtisam Habeeb Al-Azawi
{"title":"Detection of Extended Spectrum Beta Lactamase (ESBL) in Klebseilla pneumoniae Isolated from Urinary Tract Infections","authors":"Ibtisam Habeeb Al-Azawi","doi":"10.28922/qmj.2014.10.18.168-173","DOIUrl":"https://doi.org/10.28922/qmj.2014.10.18.168-173","url":null,"abstract":"This study aimed to examine the dissemination of extended spectrum B-lactamase (ESBL) producing isolates of Klebsiella pneumoniae obtained from patients with urinary tract infection who admitted Al-Diwaniya Teaching Hospital from December 2013 to April 2014. A total of 85 urine samples collected, after the first culturing thirty isolates of Klebsiella pneumoniae were obtained. The results of primary screening showed that all isolates were found to be resistance to B- actamase antibiotics (ampicillin and amoxicillin) at percentage (100%). All isolates were screened for their antibiotic resistance against 8 antibiotics of different classes using Kirby-Bauer disk diffusion method. The results showed that all isolates were resistance to ceftazidime, ceftriaxone, and cefepime in (100%), while the antibiotics tetracycline and levofloxacin (66.6%) of isolates were resistance. Half of isolates were resistance against ciprofloxacin and tobramycin, all isolates were sensitive to gentamycin in percentage (100%). Present study revealed increase the percentage of ESBL producing Klebsiella pneumoniae 11 isolates (36.7%) in compared with other studies, also the isolates were resistance to third and fourth generation of cephalosporine.","PeriodicalId":30984,"journal":{"name":"AlQadisiyah Journal for Engineering Science","volume":"10 18","pages":"168-173"},"PeriodicalIF":0.0,"publicationDate":"2017-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://qmj.qu.edu.iq/index.php/QMJ/article/download/126/125","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147906965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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