Impulse The Premier Undergraduate Neuroscience Journal最新文献

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Nitric oxide as a putative retinal axon pathfinding and target recognition cue in Xenopus laevis. 一氧化氮是小爪蟾视网膜轴突寻路和目标识别的假定线索。
Sara Berman, Andrea Morris
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引用次数: 0
The Varied Uses of Conditioned Place Preference in Behavioral Neuroscience Research: An Investigation of Alcohol Administration in Model Organisms. 条件位置偏好在行为神经科学研究中的不同用途:对模式生物酒精管理的调查。
Brandon Lucke-Wold
{"title":"The Varied Uses of Conditioned Place Preference in Behavioral Neuroscience Research: An Investigation of Alcohol Administration in Model Organisms.","authors":"Brandon Lucke-Wold","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Place conditioning procedures have been used to study human addiction to alcohol for the past several years. This experimental resource has been utilized successfully due to the fact that investigators can carefully manipulate the experimental design in order to explore specific hypotheses. Only three choices exist regarding animal response to place conditioning: aversion, preference, or no change. This review provides an in-depth analysis of five variables commonly adjusted or changed in place conditioning experiments with ethanol. These include: apparatus design, administration methods, choice of model organism, age of model organism, and model paradigms. It is suggested that the two-chamber design, the intragastric administration, the mouse model, the adolescent age group, and the pre-exposure to stress paradigm are the best current options available in place conditioning experiments with ethanol. The basis for evaluation used throughout this review is that investigators should adjust the variables employed in place conditioning experiments in a manner that most accurately represents and models complex human addiction to alcohol.</p>","PeriodicalId":30053,"journal":{"name":"Impulse The Premier Undergraduate Neuroscience Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896635/pdf/nihms789402.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34456918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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