Yaldasadat Anvar, M. Al-Haideri, T. M. Mohammad, M. Chartrand, Y. Pathak, Sahar Khademnezhad
{"title":"Exosomes’ Role in the Early Diagnosis, Progression, and Therapy of Oral and Head and Neck Squamous Cell Carcinoma","authors":"Yaldasadat Anvar, M. Al-Haideri, T. M. Mohammad, M. Chartrand, Y. Pathak, Sahar Khademnezhad","doi":"10.33582/anndentoralhealth.2023.1046","DOIUrl":"https://doi.org/10.33582/anndentoralhealth.2023.1046","url":null,"abstract":"Oral cancer includes about 2% of all malignancies, whereas the most prevalent kind is Oral Squamous Cell Carcinoma (OSCC), which constitutes for 90% of oral cancers with a poor prognosis and a superior local relapse. Since OSCC often spreads to lymph nodes in its advanced stages, the investigation of new treatment methods should be prioritized. Head and Neck Squamous Cell Carcinoma (HNSCC) is one of the predominant malignant tumors influencing human health as a result of late diagnosis and a superior rate of invasion. HNSCC patients have an overall poor survival rate despite recent improvements in treatment techniques. Hence, developing more efficient strategies continues to be a major concern. Small membrane vesicles known as exosomes are found in bodily fluids and are produced by endosomes. They have a range of mRNAs, non-coding RNAs, proteins, circular RNAs, ribosomal RNAs, tsRNAs, and piRNAs. Regulating the tumor microenvironment by exosomes provides the conditions for cancer expansion, and the transfer of their constituents to target cells is associated with the colonization, metastasis, and proliferation of OSCC and HNSCC. In the current study, we examine the part exosomes play in the emergence and identification of OSCC and HNSCC, besides their possible use in the therapy of these cancers.","PeriodicalId":294740,"journal":{"name":"Annals of Dentistry and Oral Health","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124208806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bedan Lyanda Musima, Parmjit Singh, Principal Lecturer in Orthodontics
{"title":"Use of short-term orthodontics by the specialist orthodontist","authors":"Bedan Lyanda Musima, Parmjit Singh, Principal Lecturer in Orthodontics","doi":"10.33582/2639-9210/1007","DOIUrl":"https://doi.org/10.33582/2639-9210/1007","url":null,"abstract":"STO is a term used to describe an orthodontic treatment modality whose main aim is to improve the patient’s smile by aligning the anterior teeth i.e. the ‘social six’ [1] whilst not correcting the posterior malocclusions or aiming to achieve Andrew’s Six Keys of Normal Occlusion. The treatment time usually does not last more than nine months [2]. Bedan Lyanda Musima; Parmjit Singh* 1General Dental Practitioner, Private Practice, Nairobi, Kenya 2Principal Lecturer in Orthodontics and Specialist Orthodontist, Department of Orthodontics, BPP University, London, England","PeriodicalId":294740,"journal":{"name":"Annals of Dentistry and Oral Health","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131211828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of oral health status of elderly population living in residential care facilities","authors":"O. Lowe, E. Rossopoulos","doi":"10.33582/2639-9210/1006","DOIUrl":"https://doi.org/10.33582/2639-9210/1006","url":null,"abstract":"Oral health literacy and competency are barriers to prevention, diagnosis and treatment of oral disease. In the United States, literacy skills have proven to be a strong predictor of an individual’s health status [1]. It is well documented that oral care practice and guidance available to the elderly population living in nursing homes, assisted care or other home care facilities is lacking and many of these elderly adults have difficulty Oariona Lowe, DDS1*; Evangelos Rossopoulos, DDS2 1Pediatric Dentistry, 8135 S. Painter Avenue #202, Whittier, CA 90602, USA 2Adult Dentistry, Prosthodontics, 8135 S. Painter Avenue #202, Whittier, CA 90602, USA","PeriodicalId":294740,"journal":{"name":"Annals of Dentistry and Oral Health","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125201602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Arguing over the definitions and its implication: Reconsidering centric relation in dentistry","authors":"L. Zhongjie, Lan Tingting, Liu Yang","doi":"10.33582/2639-9210/1005","DOIUrl":"https://doi.org/10.33582/2639-9210/1005","url":null,"abstract":"Centric Relation (CR) is probably the most controversial concept in dentistry, with significantly impact on education, clinical practice, and research as well. Historically, more than seven definitions were put under the term “centric relation” in the academic glossaries, [1,2] and yet no consensus is achieved. Different definitions were held between different specialists over the decades [3] and dental students in different schools were taught different versions of the concept [4]. Considering the importance of CR in many fields of dentistry, the controversy reflects the current limitation of research and technology, and also the conflict between different treatment paradigms [5]. Li Zhongjie; Lan Tingting; Liu Yang* Department of Temporomandibular Joint, State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China 610041","PeriodicalId":294740,"journal":{"name":"Annals of Dentistry and Oral Health","volume":"254 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117325748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The current and potential future uses of plateletrich plasma in orthodontics","authors":"Parmjit Singh, Kutana Namarach, Wedad Rashed Salem, Khansa Shahzadi","doi":"10.33582/2639-9210/1004","DOIUrl":"https://doi.org/10.33582/2639-9210/1004","url":null,"abstract":"","PeriodicalId":294740,"journal":{"name":"Annals of Dentistry and Oral Health","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115486654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}