发布求助
文献互助 智能选刊 最新文献

Case Reports and Images In Oncology最新文献

筛选
英文 中文
Combining Multiplex Immunohistochemistry with Computer-Aided Topographical and Single-Cell Analysis to Investigate the Mechanism of Spontaneous Regression in a Case of Metastatic Congenital Neuroblastoma 结合多重免疫组织化学与计算机辅助地形和单细胞分析探讨一例转移性先天性神经母细胞瘤自发消退的机制
Case Reports and Images In Oncology Pub Date : 2020-09-23 DOI: 10.47496/nl.crio.2020.01.07
D. Hammouche, A. Easton, L. Ma, J. Taylor, M. Marchado, J. Gray
{"title":"Combining Multiplex Immunohistochemistry with Computer-Aided Topographical and Single-Cell Analysis to Investigate the Mechanism of Spontaneous Regression in a Case of Metastatic Congenital Neuroblastoma","authors":"D. Hammouche, A. Easton, L. Ma, J. Taylor, M. Marchado, J. Gray","doi":"10.47496/nl.crio.2020.01.07","DOIUrl":"https://doi.org/10.47496/nl.crio.2020.01.07","url":null,"abstract":"This is a description of a novel combination of chromogenic multiplex immunohistochemistry, digital\u0000pathology, computer-aided cell detection and topographical analysis of tumor tissue to allow a detailed study\u0000of the immune infiltrate. This is applied to a rare clinical case, where a tumor sample is available from an\u0000infant with metastatic neuroblastoma at the point of spontaneous regression. This allowed detailed analysis\u0000of the immune infiltrate, including spatial distribution and phenotype of lymphoid and myeloid populations,\u0000with a distinction between heterogeneous areas within the intra- and extra- tumoral immune\u0000microenvironments. The mechanism of spontaneous regression in congenital neuroblastoma is poorly\u0000understood, but the data obtained suggested an immune-mediated phenomenon, characterised by an\u0000adaptive T cell driven response with a significant delayed-type hypersensitivity (granulomatous)\u0000component.\u0000","PeriodicalId":283301,"journal":{"name":"Case Reports and Images In Oncology","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132956319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Report of Objective Responses of Prostate Cancer Patients to Pharmaceutical Grade Synthetic Cannabidiol 前列腺癌患者对药物级合成大麻二酚的客观反应报告
Case Reports and Images In Oncology Pub Date : 2020-09-21 DOI: 10.47496/nl.crio.2020.01.06
Julian Kenyon, A. Davies, C. Stott
{"title":"Report of Objective Responses of Prostate Cancer Patients to Pharmaceutical Grade Synthetic Cannabidiol","authors":"Julian Kenyon, A. Davies, C. Stott","doi":"10.47496/nl.crio.2020.01.06","DOIUrl":"https://doi.org/10.47496/nl.crio.2020.01.06","url":null,"abstract":"This is an observational study of objective responses of Prostate Cancer patients to Pharmaceutical Grade\u0000Synthetic Cannabidiol. The total number of patients in the study was 12, 11 had a response of one kind or\u0000another.\u0000","PeriodicalId":283301,"journal":{"name":"Case Reports and Images In Oncology","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127219213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信