发布求助
文献互助 智能选刊 最新文献

Cardiovascular Risk Factors [Working Title]最新文献

筛选
英文 中文
Experimental Model of Cardiotoxicity 心脏毒性实验模型
Cardiovascular Risk Factors [Working Title] Pub Date : 2022-01-07 DOI: 10.5772/intechopen.101401
O. Erbaş, İ. Altuntaş, Özge Çağlar, Elif Özyilmaz, Ece Sarı, İlayda Üzümcü, Kaan Erbakan
{"title":"Experimental Model of Cardiotoxicity","authors":"O. Erbaş, İ. Altuntaş, Özge Çağlar, Elif Özyilmaz, Ece Sarı, İlayda Üzümcü, Kaan Erbakan","doi":"10.5772/intechopen.101401","DOIUrl":"https://doi.org/10.5772/intechopen.101401","url":null,"abstract":"The occurrence of heart electrophysiology dysfunction or/and muscle damage is referred to as cardiotoxicity. The heart weakens and becomes less efficient at pumping and hence circulating blood. Cardiomyopathy can be caused by a variety of factors, including viral infections, diseases such as diabetes, ischemia, hypertension, obesity, radiation therapy, antipsychotic drugs, cytotoxic drugs, most notably chemotherapeutic agents; antitumor antibiotics, monoclonal antibodies, tyrosine kinase inhibitors, platinum-based compounds, microtubule inhibitors, vinca alkaloids, antimetabolites, proteasome inhibitors, topoisomerase inhibitors, alkylating agents, corticosteroids. This chapter focuses on the mechanisms of cardiotoxicity, animal models and transgenic methods used in studies, and the effects of therapeutic agents on cardiotoxicity.","PeriodicalId":265268,"journal":{"name":"Cardiovascular Risk Factors [Working Title]","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116849607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Residual Cardiovascular Risk Factors in Dyslipidemia 血脂异常的剩余心血管危险因素
Cardiovascular Risk Factors [Working Title] Pub Date : 2021-10-14 DOI: 10.5772/intechopen.100046
Van Si Nguyen, Xuan Truong Tran, Thanh Duy Vo, Quang Truong Le
{"title":"Residual Cardiovascular Risk Factors in Dyslipidemia","authors":"Van Si Nguyen, Xuan Truong Tran, Thanh Duy Vo, Quang Truong Le","doi":"10.5772/intechopen.100046","DOIUrl":"https://doi.org/10.5772/intechopen.100046","url":null,"abstract":"Cardiovascular disease poses a major challenge for the 21st century. Although good control of blood pressure and type 2 diabetes and reducing low-density lipoprotein-cholesterol levels can improve cardiovascular outcomes, a substantial residual risk remains existed after treatment in most patient populations. Recently, many efforts have been directed at finding the important role of low high-density-lipoprotein cholesterol, high triglycerides, especially triglyceride-rich lipoproteins and lipoprotein (a) in the metabolism of atherosclerotic plaque formation Therefore, based on the recent evidence, identification and treatment of these risk factors may play a role in optimizing therapeutic strategy, particularly in high risk subjects along with conventional treatment. In clinical practice, adequate attention should be paid when screening and managing residual cardiovascular risk factors in dyslipidemia in term of individualized approach. The ongoing trials will give more answers to elucidate this important area.","PeriodicalId":265268,"journal":{"name":"Cardiovascular Risk Factors [Working Title]","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130781310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Risk Factors for Cardiovascular Diseases in Aircrew 空勤人员心血管疾病的危险因素
Cardiovascular Risk Factors [Working Title] Pub Date : 2021-09-28 DOI: 10.5772/intechopen.99905
Nathan B. Buila, Gilbert K. Kabanda, Elysee M-C. Munyoka, Jean-Marc B. Bantu, Jean René M’Buyamba-Kabangu
{"title":"Risk Factors for Cardiovascular Diseases in Aircrew","authors":"Nathan B. Buila, Gilbert K. Kabanda, Elysee M-C. Munyoka, Jean-Marc B. Bantu, Jean René M’Buyamba-Kabangu","doi":"10.5772/intechopen.99905","DOIUrl":"https://doi.org/10.5772/intechopen.99905","url":null,"abstract":"The relation of atherosclerotic cardiovascular disease (ASCVD) to not only traditional but also new and emergent risk factors has been assessed in aircrew. Total flight hours (TFH), high altitude and weightlessness exposure have been accounted among traditional risk factors for CVD among the aircrew. The risk factors do not perform in loneliness. To predict the 10 years global CV risk, several scores are being applied either based on traditional CVD risk factors only or also including new and emergent risk factors. To prevent aircrew from developing CVD, one should focus on the control of behavioral and metabolic risks as well as the polymorphe treatment of high CV risk individuals.","PeriodicalId":265268,"journal":{"name":"Cardiovascular Risk Factors [Working Title]","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133632372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vascular Calcification and Cardiovascular Risk in Chronic Kidney Disease: A Problem That Is Here to Stay 慢性肾脏疾病的血管钙化和心血管风险:一个存在的问题
Cardiovascular Risk Factors [Working Title] Pub Date : 2021-09-06 DOI: 10.5772/intechopen.99886
Eduarda Castanheiro Esteves Carias, Roberto Calças Marques, Ana Paula Andrade da Silva
{"title":"Vascular Calcification and Cardiovascular Risk in Chronic Kidney Disease: A Problem That Is Here to Stay","authors":"Eduarda Castanheiro Esteves Carias, Roberto Calças Marques, Ana Paula Andrade da Silva","doi":"10.5772/intechopen.99886","DOIUrl":"https://doi.org/10.5772/intechopen.99886","url":null,"abstract":"Cardiovascular disease is the primary cause of morbidity and mortality in chronic kidney disease (CKD) population, particularly in end stage renal disease (ESRD). This could be explained in part due to the presence of traditional cardiovascular risk factors, such as older age, hypertension, dyslipidemia and diabetes, but is also associated with nontraditional cardiovascular risk factors related to CKD, like inflammation, anemia, abnormal calcium and phosphate metabolism and extracellular fluid volume overload, which may contribute to intimal or medial wall arterial calcification. Vascular calcification (VC) is a dynamic process, resulting from the dysregulation of the balance of molecules that promote and those that inhibit this course. It is important for clinicians to both acknowledge and recognize the pathways and risk factors of VC in order to improve cardiovascular health in CKD patients. This chapter will focus on the biology of VC, the association with CKD, risk factor modification, screening and prevention of VC and cardiovascular disease in CKD patients.","PeriodicalId":265268,"journal":{"name":"Cardiovascular Risk Factors [Working Title]","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133519681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Importance of Resistance Training in the Management of Cardiovascular Disease Risk 抗阻训练在心血管疾病风险管理中的重要性
Cardiovascular Risk Factors [Working Title] Pub Date : 2021-09-01 DOI: 10.5772/intechopen.99710
Brandon S. Shaw, Gregory A. Brown, I. Shaw
{"title":"Importance of Resistance Training in the Management of Cardiovascular Disease Risk","authors":"Brandon S. Shaw, Gregory A. Brown, I. Shaw","doi":"10.5772/intechopen.99710","DOIUrl":"https://doi.org/10.5772/intechopen.99710","url":null,"abstract":"Contrary to the longstanding taboo of resistance training (RT) as a therapeutic treatment, RT has been gaining importance as a safe therapeutic option in the management of numerous diseases. Although exercise has well-documented health benefits on cardiovascular disease (CVD), the benefit of RT on CVD risk factors is not yet as widely prescribed as other modes of exercise. Due to its efficacy in the management of CVD, RT should be regarded as a complementary therapeutic treatment rather than a substitute to other modes of exercise therapy. While it is clear that RT can result in an attenuation of CVD risk, the various RT design options related to intensity and volume and how they impact on CVD risk, especially in different populations (i.e. children, elderly, women) is not yet well documented. This chapter will discuss the physiological phenomenon and benefits of RT as a therapeutic intervention aiming to manage CVD risk.","PeriodicalId":265268,"journal":{"name":"Cardiovascular Risk Factors [Working Title]","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124716014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The Effects of Linoleic Acid Consumption on Lipid Risk Markers for Cardiovascular Disease 食用亚油酸对心血管疾病脂质危险标志物的影响
Cardiovascular Risk Factors [Working Title] Pub Date : 2021-08-27 DOI: 10.5772/intechopen.99894
Erik Froyen
{"title":"The Effects of Linoleic Acid Consumption on Lipid Risk Markers for Cardiovascular Disease","authors":"Erik Froyen","doi":"10.5772/intechopen.99894","DOIUrl":"https://doi.org/10.5772/intechopen.99894","url":null,"abstract":"Cardiovascular disease (CVD) is the number one contributor to death in the United States and worldwide. Lipid risk markers for CVD include high serum concentrations of total cholesterol, low-density lipoprotein cholesterol (LDL-C), very-low-density lipoprotein cholesterol (VLDL-C), lipoprotein (a), and triglycerides, as well as low serum concentrations of high-density lipoprotein cholesterol (HDL-C). Additional factors to assess CVD risk include apolipoprotein A (associated with HDL) and apolipoprotein B (associated with LDL). A suggested dietary strategy to decrease these risk factors is to replace a portion of saturated fatty acids with unsaturated fatty acids – especially polyunsaturated fatty acids (PUFAs). One PUFA, in particular, is the essential omega-6 PUFA linoleic acid, which has been demonstrated to affect these CVD risk markers. Therefore, this chapter will discuss the effects of linoleic acid consumption on lipid risk markers for CVD in healthy individuals, the associated mechanisms, and dietary recommendations to decrease CVD risk.","PeriodicalId":265268,"journal":{"name":"Cardiovascular Risk Factors [Working Title]","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127361003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex Differences in Long-Term Trends of Psychosocial Factors and Gender Effect on Risk of Cardiovascular Diseases: Arterial Hypertension, Myocardial Infarction and Stroke 心理社会因素长期趋势的性别差异和性别对心血管疾病风险的影响:动脉高血压、心肌梗死和脑卒中
Cardiovascular Risk Factors [Working Title] Pub Date : 2021-08-26 DOI: 10.5772/intechopen.99767
V. Gafarov, D. Panov, E. Gromova, I. Gagulin, A. Gafarova, E. Krymov
{"title":"Sex Differences in Long-Term Trends of Psychosocial Factors and Gender Effect on Risk of Cardiovascular Diseases: Arterial Hypertension, Myocardial Infarction and Stroke","authors":"V. Gafarov, D. Panov, E. Gromova, I. Gagulin, A. Gafarova, E. Krymov","doi":"10.5772/intechopen.99767","DOIUrl":"https://doi.org/10.5772/intechopen.99767","url":null,"abstract":"Introduction: The study aimed to determine gender differences in the prevalence and dynamics of affective states over a long period, i.e., 23 years, and to establish their effect on the risk of cardiovascular diseases (CVD), i.e., arterial hypertension (AH), myocardial infarction (MI), and stroke among the population aged 25–64 in Russia / Siberia. Methods: Between 1994 and 2017, we conducted 4 screening surveys of representative samples (totalling 4,815 people) under the international programs MONICA and HAPIEE in Russia / Siberia. To determine the sex differences in cardiovascular risk from 1994 to 2010, we observed cohorts formed from the screened individuals without CVD and diabetes mellitus (DM). Results: High levels of affective states in the period from 1994 to 2003, especially in women, were replaced by a downward trend in 2013. At the same time, there was a reduction in the gender gap in terms of frequency of depression lower 1%, and men in the younger age groups reported higher levels of personal anxiety (49.3% vs 46.1% in adults aged 35-44y) and vital exhaustion (16.9% vs 15.6%) than women in 2017. We found that men with unfavourable levels of affective states have a 3–5 fold higher risk of hypertension and stroke, while women have a higher risk of myocardial infarction (p for all < 0.05). Hostility in men is associated with a negative risk of myocardial infarction and stroke (HR=0.3 and HR=0.29, respectively; p for all < 0.05). However, this was levelled out by unfavourable social characteristics. Conclusions: The downward trends in prevalence of psychosocial factors were unstable and associated with reduced gender gap for affective states. It had a significant impact on the gender magnitude of cardiovascular risk.","PeriodicalId":265268,"journal":{"name":"Cardiovascular Risk Factors [Working Title]","volume":"315 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122917300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信