SCIENCE WORLD JOURNAL OF SKIN DISEASES AND VENEREOLOGY最新文献

Treatment of Pemphigus Vulgaris and Pemphigus Foliaceus: Experience with 30 Patients 寻常型天疱疮和叶状天疱疮30例的治疗体会

SCIENCE WORLD JOURNAL OF SKIN DISEASES AND VENEREOLOGY Pub Date : 1900-01-01 DOI: 10.47690/SWJSDV.2020.1104

N. Fernandes

{"title":"Treatment of Pemphigus Vulgaris and Pemphigus Foliaceus: Experience with 30 Patients","authors":"N. Fernandes","doi":"10.47690/SWJSDV.2020.1104","DOIUrl":"https://doi.org/10.47690/SWJSDV.2020.1104","url":null,"abstract":"Pemphigus vulgaris and Pemphigus foliaceus are chronic, painful diseases which treatment causes great impact. This study focuses on the age, gender, mucosal lesions, therapy with oral prednisone, clinical remission rates and side effects. Material And Methods : Six males/15 females with Pemphigus vulgaris and three males/six females with non-endemic pemphigus foliaceus attended at Hospital Universitario from 2003 to 2018 were submitted to histopathology through skin or mucosa biopsy. Oral prednisone (monotherapy) in seven Pemphigus vulgaris and two pemphigus foliaceus; in case of no control or relapses, association with cyclophosphamide pulse therapy (12PV/4PF), dexamethasone pulse therapy (ten PV/two PF), hydroxychloroquine (three PV/four PF), azathioprine (five PV),methotrexate (four PV/one PF), immunoglobulin cycles (two PV/two PF). Results : Mostly patients were female aged 30-59 years old; oral mucosal lesions in 19 (90,4%) pemphigus vulgaris. After a ten year period of monitoring it was observed in the group of monotherapy: one PV/one PF achieved complete remission on low dose of prednisone; two PV achieved partial remission on low dose and four PV/one PF on high dose. In the group with combined drugs, four PV were off prednisone, four PV/one PF achieved complete remission on low dose and two PF on high dose; two PV/three PF achieved partial remission on low dose and four PV/one PF on high dose. The most common side effects of prednisone were mucocutaneous candidiasis, arterial hypertension, subcapsular posterior cataracts, bacterial and viral infections and diabetes mellitus. Conclusion : Both diseases ran a chronic and unpredictable course which management was extremely difficult. Females with pemphigus vulgaris developed severe multiple mucosal lesions.","PeriodicalId":262120,"journal":{"name":"SCIENCE WORLD JOURNAL OF SKIN DISEASES AND VENEREOLOGY","volume":"276 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123453049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pemphigus Vegetans In The Scalp: A Therapeutic Challenge 天疱疮素食者在头皮:治疗的挑战

SCIENCE WORLD JOURNAL OF SKIN DISEASES AND VENEREOLOGY Pub Date : 1900-01-01 DOI: 10.47690/SWJSDV.2020.1105

N. Fernandes

引用次数: 0

Ainhum. Presentation of Clinical and Sonographic Findings in A Colombian Patient 阿洪病。一位哥伦比亚病人的临床和超声表现

SCIENCE WORLD JOURNAL OF SKIN DISEASES AND VENEREOLOGY Pub Date : 1900-01-01 DOI: 10.47690/swjsdv.2020.1101

Sandra Muvdi, Claudia González

引用次数: 0

Demographic and Clinical Characteristics of Patients with Eyelid Eczema in a Referral Center from 2004 to 2018 2004 - 2018年某转诊中心眼睑湿疹患者的人口统计学和临床特征

SCIENCE WORLD JOURNAL OF SKIN DISEASES AND VENEREOLOGY Pub Date : 1900-01-01 DOI: 10.47690/SWJSDV.2020.1106

M. Hafner, Victoria Elia, Rosana Lazzarini, I. Duarte

{"title":"Demographic and Clinical Characteristics of Patients with Eyelid Eczema in a Referral Center from 2004 to 2018","authors":"M. Hafner, Victoria Elia, Rosana Lazzarini, I. Duarte","doi":"10.47690/SWJSDV.2020.1106","DOIUrl":"https://doi.org/10.47690/SWJSDV.2020.1106","url":null,"abstract":"Eyelid eczema have many etiologies, among them contact dermatitis.The investigation of suspect cases includes patients’ history, clinical examination, and patch tests. The goals of this study were: to determine demographical and clinical characteristics of patients with eyelid eczema patch tested between 2004 and 2018; to determine established diagnoses; and to identify responsible allergens. Medical records of patients with eyelid eczema who underwent patch testing were analyzed. This study included 228 patients, of which 89.5% were women, with a mean age of 45 years. Regarding clinical condition, 64.5% presented eczema lesions in other body parts besides the eyelids, mainly in other facial sites (51.8%). Final diagnosis was allergic contact dermatitis (ACD) in 61%, atopic dermatitis (AD) in 12.7%, undefined in 12.3%, irritant contact dermatitis in 7.9%, superimposing of ACD and AD in 3.1%, and other diagnoses in 3.1% of patients. Regarding patch tests, 64.4% of patients had at least one relevant positive allergen, the majorones being: toluene-sulfonamide-formaldehyde resin, paraphenylenediamine, nickel sulfate, fragrance mix I, neomycin, and Kathon CG. As main etiologies in ACD cases, nail polish (36%), topical medicaments (27.2%), non-specified cosmetics (24.5%), hair dye (13.6%), metals (15.6%), rubber (6.8%), and shampoos (4%) could be identified. Thereby, results presented compatibility to data in the literature: predominance of women and most prevalent final diagnosis of cosmetic-related ACD. Thus, when dealing with patients with eyelid eczema, investigation with patch testing is fundamental.","PeriodicalId":262120,"journal":{"name":"SCIENCE WORLD JOURNAL OF SKIN DISEASES AND VENEREOLOGY","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125023456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Onychomycosis Treatment with Fotona Laser Fotona激光治疗甲真菌病

SCIENCE WORLD JOURNAL OF SKIN DISEASES AND VENEREOLOGY Pub Date : 1900-01-01 DOI: 10.47690/swjsdv.2021.1202

A. A., Arellano-Montalvo D, Arellano-Montalvo A

引用次数: 0

Necrobiotic Xanthogranuloma With Non- Progressive Hematological Dyscrasia, A Case Report 坏死性黄色肉芽肿合并非进行性血液病1例报告

SCIENCE WORLD JOURNAL OF SKIN DISEASES AND VENEREOLOGY Pub Date : 1900-01-01 DOI: 10.47690/SWJSDV.2020.1102

Jhonatan Q. Ossa, F. Jaramillo‐Ayerbe, J. Cardona

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Girdled and Hemmed In -Perivascular Epithelioid Cell Tumour 束状和束状血管周围上皮样细胞瘤

SCIENCE WORLD JOURNAL OF SKIN DISEASES AND VENEREOLOGY Pub Date : 1900-01-01 DOI: 10.47690/SWJSDV.2020.1103

Anu Bajaj

{"title":"Girdled and Hemmed In -Perivascular Epithelioid Cell Tumour","authors":"Anu Bajaj","doi":"10.47690/SWJSDV.2020.1103","DOIUrl":"https://doi.org/10.47690/SWJSDV.2020.1103","url":null,"abstract":"PREFACE Exceptional neoplasia with perivascular clear cell and epithelioid cell differentiation are diverse and constituted by angiomyolipoma, clear cell “sugar tumour” of pulmonary and extra pulmonary sites, clear cell myomelanocytic tumour offalciform ligament or ligamentum teres and lymphangioleiomyomatosis on account of distinctive histological manifestations. Variable genetic and malignant biological behaviour is exemplified within perivascular epithelioid cell tumours. Perivascular epithelioid cell tumour (PEComa) is a contemporary neoplasm of mesenchymal origin emerging within diverse sites while representing a classified group with distinctive histology and immune histochemical staining. The tumefaction is composed of epithelioid cells which demonstrate dual properties of smooth muscle and melanocytes with pertinent immune reactivity. Cellular component tends to aggregate around and circumscribe blood vessels, thus engendering the acronym “PEComa”. Perivascular epithelioid cell tumour was initially described by Bonetti et al in 1992 [1]. Zamboni et al in 1996 documented perivascular epithelioid cell tumour of the pancreas and denominated the neoplasm as “sugar tumour” on account of clear, glycogen rich, cytoplasm imbued within perivascular epithelioid cells. A normal counterpart of perivascular epithelioid cell tumour is absent [2].","PeriodicalId":262120,"journal":{"name":"SCIENCE WORLD JOURNAL OF SKIN DISEASES AND VENEREOLOGY","volume":"254 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133493969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0