Journal of Neuroscience and Behavioral Health最新文献

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Gender-based violence and associated factors among high school female students in Ethiopia: Systematic review and meta-analysis 埃塞俄比亚高中女生性别暴力及其相关因素:系统回顾与元分析

Journal of Neuroscience and Behavioral Health Pub Date : 2023-03-31 DOI: 10.5897/jnbh2022.0163

Tinsae Techilo, Getinet Wondale, Shumet Shegaye, Melkam Mamaru

{"title":"Gender-based violence and associated factors among high school female students in Ethiopia: Systematic review and meta-analysis","authors":"Tinsae Techilo, Getinet Wondale, Shumet Shegaye, Melkam Mamaru","doi":"10.5897/jnbh2022.0163","DOIUrl":"https://doi.org/10.5897/jnbh2022.0163","url":null,"abstract":"Gender-based violence is a serious public health problem. The prevalence of sexual violence against female students in Ethiopia has not been systematized, according to many dispersed studies. Therefore, the purpose of this systematic review and meta-analysis estimate cumulative prevalence of sexual violence and associated factors among high school female students, in Ethiopia. A systematic review and meta-analysis conducted. Different primary articles that assessed violence against high school female students in Ethiopia extracted by using Microsoft excel and exported to STATA version 11 for further analysis. Random-effect model meta-analysis was used to estimate the pooled prevalence and effect of each study with a 95% confidence interval. Funnel plots analysis and egger test regression were conducted to detect the presence of publication bias. A sensitivity test and sub-group analysis were conducted. A total of studies with 5,441 participants were included. Estimated pooled prevalence of violence against high school female students in Ethiopia was 45.25, with a 95% CI (34.59-55.91). Female students who had a history of sexual intercourse were about 7 (OR=7.23; 95% CI: 1.03-51.02) times more likely to have gender-based violence when compared with females who had no sexual intercourse history. In our systematic review and meta-analysis, magnitude of violence against female students is high in Ethiopia. It is recommended for high school directors, the regional education office, and the ministry of education to give special attention and work on female students to minimize gender-based violence.","PeriodicalId":261839,"journal":{"name":"Journal of Neuroscience and Behavioral Health","volume":"165 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130547805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuroprotective activity of Conyza aegyptiaca hydroethanolic extract against ethanol-induced neurodegeneration in adolescent Wistar rats brain 埃及连翘水乙醇提取物对乙醇诱导的青春期Wistar大鼠脑神经变性的神经保护作用

Journal of Neuroscience and Behavioral Health Pub Date : 2022-07-31 DOI: 10.5897/jnbh2022.0162

T. K. Yendubé, Digbandjoa Kanfitine, Kpemissi Mabozou, Diallo Aboudoulatif, D. K. Simplice, Lawson-evi Povi, Metowogo Kossi, Eklu-Gadegbeku Kwashie

{"title":"Neuroprotective activity of Conyza aegyptiaca hydroethanolic extract against ethanol-induced neurodegeneration in adolescent Wistar rats brain","authors":"T. K. Yendubé, Digbandjoa Kanfitine, Kpemissi Mabozou, Diallo Aboudoulatif, D. K. Simplice, Lawson-evi Povi, Metowogo Kossi, Eklu-Gadegbeku Kwashie","doi":"10.5897/jnbh2022.0162","DOIUrl":"https://doi.org/10.5897/jnbh2022.0162","url":null,"abstract":"Alcohol consumption is a common well-known source of brain damages. This work aimed to evaluate the neuroprotective effect of Conyza aegyptiaca against ethanol-induced neurodegeneration in a Wistar rat binge drinking model. Animals, pretreated orally once a day during 3 days with the hydroethanolic extract of C. aegyptiaca (HECA 250 and 500 mg/kg), received daily intraperitoneally 7 g/kg of ethanol for 3 more days, concomitantly with HECA. Behavioral studies, brains tissue oxidative stress markers (MDA, GSH) assays, blood cell count and biochemistry analysis were performed. In vitro antioxidant activity using DPPH and FRAP tests and phytochemical tests were also realized. The negative geotaxis test showed that HECA 500 rats took significantly less time (3.24 ± 0.49 s, P<0.05 vs Ethanol control) compared to their congeners of Ethanol control group (6.80 ± 1.267 s, P<0.01 vs Sham). HECA treatment lowered significantly MDA levels (P<0.05 vs Ethanol control) and significantly increased GSH levels (P<0.05 vs Ethanol control). HECA treatment also significantly reduced the platelet count (P<0.001 vs Ethanol control). Ethanol 7 g/kg i.p raised hepatic function markers ALT and AST (respectively +27%, P<0.01 and +58.29%, P<0.01 vs Sham), effects significantly reversed by HECA treatments. DPPH scavenging activity with an IC50 of 368.769 ± 16.467 µg/mL and ferric ion reducing power with an EC50 of 139.65 ± 7.14 µg/mL should be related to the polyphenolic compounds found in HECA, tannins and flavonoids in particular. C. aegyptiaca could therefore potentially protect the brain against situations of neurodegeneration such as those observed in acute ethanol neurotoxicity.","PeriodicalId":261839,"journal":{"name":"Journal of Neuroscience and Behavioral Health","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129357217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictors of stimulants use among physicians in a Nigerian tertiary health institution in Sokoto, Northwest Nigeria 在尼日利亚西北部索科托的尼日利亚三级卫生机构的医生兴奋剂使用的预测因素

Journal of Neuroscience and Behavioral Health Pub Date : 2018-06-30 DOI: 10.5897/jnbh2018.0151

A. Habibullah, M. A. Muhammad, M. Kabiru, M. Kabiru, T. Abdulfatai

{"title":"Predictors of stimulants use among physicians in a Nigerian tertiary health institution in Sokoto, \u0000Northwest Nigeria","authors":"A. Habibullah, M. A. Muhammad, M. Kabiru, M. Kabiru, T. Abdulfatai","doi":"10.5897/jnbh2018.0151","DOIUrl":"https://doi.org/10.5897/jnbh2018.0151","url":null,"abstract":"Studies suggest that prevalence rates of stimulants use and abuse among healthcare professionalss is similar to rates in the general population. Majority of the studies on stimulants use carried out in Nigeria mainly focused on students of secondary and tertiary institutions, thus, there is the need to conduct similar study among physicians in Nigeria. This study aimed to assess the pattern and predictors of the use of stimulants among physicians in Usmanu Danfodiyo University Teaching Hospital (UDUTH), Sokoto, North-west Nigeria. A descriptive cross sectional study was conducted among physicians of all ranks in UDUTH, Sokoto. Stratified sampling technique was used to select 107 participants and a set of semi- structured self-administered questionnaires were used to obtain data from the participants. Data were analyzed using IBM SPSS version 20. Prevalence of current stimulant use was 59% and majority (83%) of the respondents take coffee, 54.5% take kola nut, 35.1% take caffeinated energy drinks and only 2% of the respondents take cigarette. Among the 87.9% that have ever used stimulants, 41% (n=43) have stopped. Majority of them (70.97%) take stimulants only once in a day and none of them take any stimulant via parenteral route. Rank of the respondent was the strongest predictor of current stimulant use (OR= 3.741, p=0.017, 95% CI=1.270-11.021). The prevalence of stimulants use among physicians is quite high. Coffee is the most consumed stimulant and rank of the physicians is the strongest predictor of current stimulants use. There is also need to assess the effect of stimulants consumption among physicians considering the high prevalence of its consumption among them. \u0000 \u0000 Key words: Predictors, stimulants, physicians, Sokoto, Nigeria.","PeriodicalId":261839,"journal":{"name":"Journal of Neuroscience and Behavioral Health","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125984879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2