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CNS High Grade Glioma 中枢神经系统高级别胶质瘤
Central Nervous System Tumors Pub Date : 2022-01-19 DOI: 10.5772/intechopen.99984
Liam Chen
{"title":"CNS High Grade Glioma","authors":"Liam Chen","doi":"10.5772/intechopen.99984","DOIUrl":"https://doi.org/10.5772/intechopen.99984","url":null,"abstract":"Since the publication of the 2016 edition of the WHO Classification of CNS Tumors, advances in neuropathology have enhanced our understanding of the molecular underpinnings of CNS tumors, providing new elements to refine their classification and improve pathological diagnosis of these neoplasms. This chapter will review the highlights of the updated recommendations which provide guidance for how even in the absence of histopathological characteristics of the highest malignancy grade, molecular markers can be used to reach a diagnosis of glioblastoma, IDH–wild-type or astrocytoma, IDH-mutant, grade IV. These changes have important implications for the management of patients with CNS tumors in current neuro-oncology practice.","PeriodicalId":253297,"journal":{"name":"Central Nervous System Tumors","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115378914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Awake Craniotomy and Brain Mapping for Brain Tumor Resection in Pediatric Patients 儿童脑肿瘤切除术的清醒开颅和脑测绘
Central Nervous System Tumors Pub Date : 2021-04-06 DOI: 10.5772/INTECHOPEN.97101
Roberto García-Navarrete, J. Terrazo-Lluch, A. Marhx-Bracho, Ericka León Alvárez, Natael Olvera González, Beatriz Alvárez-Mora, R. Silva, Cointa Arroyo, Vianey Maceda Morales, L. M. Cordero, Daniel Magos Rodríguez, S. L. Lizarraga-Lopez, Ana María Niembro Zúñiga, J. Medrano
{"title":"Awake Craniotomy and Brain Mapping for Brain Tumor Resection in Pediatric Patients","authors":"Roberto García-Navarrete, J. Terrazo-Lluch, A. Marhx-Bracho, Ericka León Alvárez, Natael Olvera González, Beatriz Alvárez-Mora, R. Silva, Cointa Arroyo, Vianey Maceda Morales, L. M. Cordero, Daniel Magos Rodríguez, S. L. Lizarraga-Lopez, Ana María Niembro Zúñiga, J. Medrano","doi":"10.5772/INTECHOPEN.97101","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.97101","url":null,"abstract":"Brain tumor resection in pediatric patients constitutes a real challenge. In order to improve survival and to preserve neurological function, we will further on describe our experience with awake craniotomy and functional mapping for brain tumor resection in pediatric patients. Although our experience with this technique was relatively short, we did not observe complications, and a gross total resection was successfully achieved in all cases. In the postoperative period we did not find any new deficiency in our patients. We observed functional recovery - motor and sensitive aphasia, motor strength improvement in hemiplegic patients, and recovery of neurodevelopmental milestones during follow-up. In our experience, the use of awake craniotomy and brain mapping for brain tumor resection in pediatric patients is truly safe and reliable.","PeriodicalId":253297,"journal":{"name":"Central Nervous System Tumors","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114915281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patterns of Care of Childhood Cancers in India 印度儿童癌症护理模式
Central Nervous System Tumors Pub Date : 2021-03-16 DOI: 10.5772/INTECHOPEN.96709
R. Digumarti, V. Koyyala
{"title":"Patterns of Care of Childhood Cancers in India","authors":"R. Digumarti, V. Koyyala","doi":"10.5772/INTECHOPEN.96709","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96709","url":null,"abstract":"Management of childhood cancers in India has seen a new high in last few decades due to collaborative efforts of Physicians and organizations- both governmental and non-governmental. However, care is still heterogenous in this vast country. The problems span from a lack of data to programs for tackling cancers at the community level and lack of awareness among parents and physicians on childhood cancers, along with a nihilistic attitude and stigma attached to cancers even in this digital era. In this article, we describe the milestones in the development of Pediatric Oncology as a specialty, of cancer registries, of diagnostic armamentarium, access to affordable drugs, and, palliative care for children with cancers in India, that perhaps reflects care in other developing countries.","PeriodicalId":253297,"journal":{"name":"Central Nervous System Tumors","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123919542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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