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Insights of Neuro Oncology最新文献

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T-DM1 and AVM - Coincidence or Causation: Case Report T-DM1 和 AVM--巧合还是因果关系？病例报告
Insights of Neuro Oncology Pub Date : 2023-12-31 DOI: 10.36959/828/339
Mittal Anika, Tan Hendrick, Chan Arlene, Phatouros Constantine Chris, Lam Mihn, Harper Chris
{"title":"T-DM1 and AVM - Coincidence or Causation: Case Report","authors":"Mittal Anika, Tan Hendrick, Chan Arlene, Phatouros Constantine Chris, Lam Mihn, Harper Chris","doi":"10.36959/828/339","DOIUrl":"https://doi.org/10.36959/828/339","url":null,"abstract":"Background: Trastuzumab emtansine (T-DM1) is a novel agent used for the patients with human epidermal growth factor receptor (HER-2) positive breast cancer. Prolonged use of T-DM1 has been shown to cause rare adverse effects, such as hereditary haemorrhagic telangiectasia (HHT)-like symptoms and vascular malformation. The authors present a case of HHT-like symptoms and new brain arteriovenous malformation (AVM) in the setting of T-DM1 therapy for breast cancer. Observation: A 77-year-old lady with a background of metastatic breast cancer who developed HHT-like mucocutaneous clinical manifestation during treatment with T-DM1, which regressed at nine months following cessation of T-DM1. She was found to have new brain AVMs four years after commencement of T-DM1 therapy in the absence of other risk factors for AVM. Conclusion: Given the increasing use of T-DM1 for metastatic breast cancer, it is imperative for clinicians to be aware of the potential development of brain AVM whilst on T-DM1 via HHT linkage.","PeriodicalId":252378,"journal":{"name":"Insights of Neuro Oncology","volume":"118 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139135366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vascular Parkinsonism: A Clinical Study of Response to Dopaminergic Therapy and Patterns of Brain Vascular Lesions in a Group of Patients 血管性帕金森病:一组患者多巴胺能治疗反应和脑血管病变模式的临床研究
Insights of Neuro Oncology Pub Date : 2022-02-12 DOI: 10.36959/828/337
Zarola Flora
{"title":"Vascular Parkinsonism: A Clinical Study of Response to Dopaminergic Therapy and Patterns of Brain Vascular Lesions in a Group of Patients","authors":"Zarola Flora","doi":"10.36959/828/337","DOIUrl":"https://doi.org/10.36959/828/337","url":null,"abstract":"","PeriodicalId":252378,"journal":{"name":"Insights of Neuro Oncology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129304766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metastatic Meningioma: A Case Report and Literature Review 转移性脑膜瘤1例报告及文献复习
Insights of Neuro Oncology Pub Date : 2021-06-14 DOI: 10.36959/828/336
Chong Caris
{"title":"Metastatic Meningioma: A Case Report and Literature Review","authors":"Chong Caris","doi":"10.36959/828/336","DOIUrl":"https://doi.org/10.36959/828/336","url":null,"abstract":"Metastatic meningioma is extremely rare. We describe a case of a female patient who was diagnosed with metastatic meningioma on investigation of a right perihilar lung lesion. A literature search and review was performed to evaluate best management and treatment options of this condition.","PeriodicalId":252378,"journal":{"name":"Insights of Neuro Oncology","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129588776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunohistochemical and Biomolecular Characteristics of Craniopharyngiomas: A Single Institution Experience from Southern Italy 颅咽管瘤的免疫组织化学和生物分子特征:来自意大利南部的单一机构经验
Insights of Neuro Oncology Pub Date : 2019-02-07 DOI: 10.36959/828/333
A. Ieni, Roberta Cardia, G. Giuffrè, G. Tuccari
{"title":"Immunohistochemical and Biomolecular Characteristics of Craniopharyngiomas: A Single Institution Experience from Southern Italy","authors":"A. Ieni, Roberta Cardia, G. Giuffrè, G. Tuccari","doi":"10.36959/828/333","DOIUrl":"https://doi.org/10.36959/828/333","url":null,"abstract":"In the present paper, The Authors discuss the histological and immunohistochemical aspects observed in a casuistry of craniopharyngiomas (CP), identifying not only subtypes (papillary or adamantinomatous), but also their proliferative activity and molecular pathways.","PeriodicalId":252378,"journal":{"name":"Insights of Neuro Oncology","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129724654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pituitary Adenoma with Evidence of Intracranial Extramedullary Haematopoiesis 垂体腺瘤伴颅内髓外造血
Insights of Neuro Oncology Pub Date : 1900-01-01 DOI: 10.36959/828/338
Bharti Jyotsna Naresh
{"title":"Pituitary Adenoma with Evidence of Intracranial Extramedullary Haematopoiesis","authors":"Bharti Jyotsna Naresh","doi":"10.36959/828/338","DOIUrl":"https://doi.org/10.36959/828/338","url":null,"abstract":"","PeriodicalId":252378,"journal":{"name":"Insights of Neuro Oncology","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127497662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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