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Journal of Hematology and Blood Disorders最新文献

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High Prevalence of Morphological Abnormality on Peripheral Blood Cells Among Patients in Public Hospitals, Southern Ethiopia 埃塞俄比亚南部公立医院患者外周血形态异常的高发率
Journal of Hematology and Blood Disorders Pub Date : 2022-05-04 DOI: 10.15744/2455-7641.8.102
A. Aklilu
{"title":"High Prevalence of Morphological Abnormality on Peripheral Blood Cells Among Patients in Public Hospitals, Southern Ethiopia","authors":"A. Aklilu","doi":"10.15744/2455-7641.8.102","DOIUrl":"https://doi.org/10.15744/2455-7641.8.102","url":null,"abstract":"Introduction: Morphologically abnormal blood cells in peripheral blood of a person reflect underlying pathological condition affecting formation, function, and lifespan of these cells. A properly identified morphological defect in peripheral blood cells is important to manage anemia, leukemia and other disorders of blood. This study aimed to assess magnitude and severity of morphological abnormality in blood cells of patients with abnormal complete blood count in public hospitals found in southern Ethiopia. Method: A facility-based cross-sectional study was conducted from January 01 to March 31, 2019 among five public hospitals in Southern Ethiopia. Peripheral blood sample and socio-demographic data were collected from 423 patients with abnormal complete blood count. Thin blood smear was prepared by Wedge method, stained with Wright’s Stain, and examined under microscope by 1000X magnification to detect and characterize abnormality in blood cells’ morphology. Descriptive statistical analysis was done using Statistical Package for Social Sciences version 20.0, and results are presented in tables and figures. Result: Prevalence of blood cell morphological abnormality was 63.8%. From this, 21.8% is marked and 78.2% is moderate abnormality. In 41.9% of the affected patients, the defect involved at least two blood cell types mainly affecting red blood cells. Females (73.8%), children (70.1%) and elderly (82.1%) carried higher prevalence of the abnormality. Conclusion: High prevalence of abnormality in PBS morphology was observed, chiefly among female, children and elderly. Stakeholders should work to alleviate the high prevalence, with particular attention to women, children and old-age people.","PeriodicalId":251278,"journal":{"name":"Journal of Hematology and Blood Disorders","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123693168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of Hemostatic Parameters with Poly (ADP-ribose) Polymerase-1 (PARP-1) Polymorphisms, Mutations, Laboratory, and Clinical Characteristics in 114 Patients with Philadelphia-Negative Myeloproliferative Neoplasms 114例费城阴性骨髓增生性肿瘤患者止血参数与聚(adp -核糖)聚合酶-1 (PARP-1)多态性、突变、实验室和临床特征的相关性
Journal of Hematology and Blood Disorders Pub Date : 2021-08-01 DOI: 10.15744/2455-7641.7.103
G. N.
{"title":"Correlation of Hemostatic Parameters with Poly (ADP-ribose) Polymerase-1 (PARP-1) Polymorphisms, Mutations, Laboratory, and Clinical Characteristics in 114 Patients with Philadelphia-Negative Myeloproliferative Neoplasms","authors":"G. N.","doi":"10.15744/2455-7641.7.103","DOIUrl":"https://doi.org/10.15744/2455-7641.7.103","url":null,"abstract":"","PeriodicalId":251278,"journal":{"name":"Journal of Hematology and Blood Disorders","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128189225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Induce Hyperlipidemia in Rats Using High Fat Diet Investigating Blood Lipid and Histopathology 高脂饮食诱导高脂血症大鼠血脂及组织病理学研究
Journal of Hematology and Blood Disorders Pub Date : 2018-08-01 DOI: 10.15744/2455-7641.4.104
Karam I, Ma N, Yang Y-J, lim j.y
{"title":"Induce Hyperlipidemia in Rats Using High Fat Diet Investigating Blood Lipid and Histopathology","authors":"Karam I, Ma N, Yang Y-J, lim j.y","doi":"10.15744/2455-7641.4.104","DOIUrl":"https://doi.org/10.15744/2455-7641.4.104","url":null,"abstract":"The experiment was conducted to investigate the effect of induced hyperlipidemia in SD rats fed with high fat diet (HFD) for 7 weeks on blood lipid profile and possible pathological changes in liver, stomach, intestine, heart, spleen, lung and kidney. There were significant differences in most rats which induced hyperlipidemia throughout the experimental period with the blood lipid levels and histopathology. Abstract","PeriodicalId":251278,"journal":{"name":"Journal of Hematology and Blood Disorders","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132103413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Successful Treatment of Acquired Amegakaryocytic Thrombocytopenia (AAT) with Cyclosporine and Eltrombopag: A Case Report 环孢素联合埃曲巴格治疗获得性无核细胞血小板减少症(AAT) 1例
Journal of Hematology and Blood Disorders Pub Date : 2018-08-01 DOI: 10.15744/2455-7641.4.101
E PardaldelaMano, G. Martín-Sánchez, L. Rm, F. Ma, G. Ja, G. Martín-Núñez
{"title":"Successful Treatment of Acquired Amegakaryocytic Thrombocytopenia (AAT) with Cyclosporine and Eltrombopag: A Case Report","authors":"E PardaldelaMano, G. Martín-Sánchez, L. Rm, F. Ma, G. Ja, G. Martín-Núñez","doi":"10.15744/2455-7641.4.101","DOIUrl":"https://doi.org/10.15744/2455-7641.4.101","url":null,"abstract":"Acquired amegakaryocytic thrombocytopenia is an unusual hematological disorder characterized by severe thrombocytopenia in association with a marked decrease, or the absence, of megakaryocytes in bone marrow. Its pathogenesis is not well understood and its clinical course is variable. Several treatments have been used, producing different responses. We present a case that was successfully treated with a calcineurin inhibitor combined with a thrombopoiesis-stimulating agent. Abstract","PeriodicalId":251278,"journal":{"name":"Journal of Hematology and Blood Disorders","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121153936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of the different FAB sub type of Acute Myeloid Leukemia related to hematological parameters in Sudanese 苏丹人不同FAB亚型急性髓系白血病患病率与血液参数的关系
Journal of Hematology and Blood Disorders Pub Date : 2017-08-01 DOI: 10.15744/2455-7641.3.102
Sitelbanat H Omer, Kordofani Aa, Osmanov Im, M. Oh, Hisham N. Altayb, B. K. Elamin
{"title":"Prevalence of the different FAB sub type of Acute Myeloid Leukemia related to hematological parameters in Sudanese","authors":"Sitelbanat H Omer, Kordofani Aa, Osmanov Im, M. Oh, Hisham N. Altayb, B. K. Elamin","doi":"10.15744/2455-7641.3.102","DOIUrl":"https://doi.org/10.15744/2455-7641.3.102","url":null,"abstract":"Volume 3 | Issue 1 Prevalence of the different FAB sub type of Acute Myeloid Leukemia related to hematological parameters in Sudanese Sitelbanat H.Omer*1, Kordofani AA2, Osman IM3, Musa OH4, Altayb HN5, and Bahaeldin K.Elamin6 1Department of Hematology, Al-Gad international college for medical science, Saudi Arabia 2Department of Pathology, Faculty of medicine, University of Khartoum, Khartoum, Sudan 3Department of Pathology, Faculty of medicine, Alzaiem Alazhari University, Khartoum, Sudan 4Fedail specialized hospital, Khartoum, Sudan 5College of medical laboratory science, Sudan University of Science and Technology, Khartoum, Sudan 6Department Of Microbiology, Faculty Of Medical Laboratory Sciences University Of Khartoum, Sudan *Corresponding author: Sitelbanat H.Omer, Department of Hematology, Al-Gad international college for medical science, Saudi Arabia, E-mail: setosman@hotmail.com","PeriodicalId":251278,"journal":{"name":"Journal of Hematology and Blood Disorders","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116427985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
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