Presse Medicale (Paris, France : 1983)最新文献

[Severe Streptococcus agalactiae infection of the diabetic foot.] [糖尿病足严重无乳链球菌感染]

IF 2.7

Presse Medicale (Paris, France : 1983) Pub Date : 2005-04-01

Catherine Altrichter Loan, Laurence Legout, Mathieu Assal, Peter Rohner, Pierre Hoffmeyer, Louis Bernard

{"title":"[Severe Streptococcus agalactiae infection of the diabetic foot.]","authors":"Catherine Altrichter Loan, Laurence Legout, Mathieu Assal, Peter Rohner, Pierre Hoffmeyer, Louis Bernard","doi":"","DOIUrl":"","url":null,"abstract":"A DELETERIOUS ROLE OF STREPTOCOCCUS AGALACTIAE?: Introduction Screening strategies among pregnant women have decreased the incidence of group B Streptococcus, which causes severe neonatal infections. The incidence of these infections has increased among diabetic patients, however. OBJECTIVES: To specify the characteristics of diabetic foot infections in which surgical samples have isolated one or several germs including group B Streptococcus, study its risk factors and determine its course. Materials and methods We retrospectively evaluated the records of all patients admitted to the University Hospital of Geneva from January 1999 through October 2004, with diagnoses of severe foot infection (+/- osteomyelitis) documented during surgery. RESULTS: Twenty-five severe diabetic foot infections were identified, 21 with osteomyelitis. The most common risk factors were age older than 60 years (n=10), chronic renal failure (n=7), severe arteriopathy (n=6), and immune depression (n=2). Most lesions were classified as grade 3 or 4 of Wagner's classification. 80% of the surgical samples were polymicrobial. Blood cultures were positive in 4 patients, one in septic shock. Half the patients (n=13) underwent amputation, despite initially appropriate antibiotic treatment. No patients died but 3 relapsed. CONCLUSION: Group B streptococcal foot infections often occur in fragile patients with immune depression or severe arterial disease. Despite intensive antibiotic therapy and adequate debridement, amputation is often required in diabetic patients because of severe damage to the tissue and poor vascularization.","PeriodicalId":250357,"journal":{"name":"Presse Medicale (Paris, France : 1983)","volume":" ","pages":"491-494"},"PeriodicalIF":2.7,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40925803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[High-dose buprenorphine substitution during incarceration.] [监禁期间大剂量丁丙诺啡替代]

IF 2.7

Presse Medicale (Paris, France : 1983) Pub Date : 2005-04-01

Catherine Reynaud-Maurupt, Yves Caer, Noëlle Escaffre, Murielle Gagneau, Anne Galinier, Jean-Noël Marzo, Fadi Meroueh

{"title":"[High-dose buprenorphine substitution during incarceration.]","authors":"Catherine Reynaud-Maurupt, Yves Caer, Noëlle Escaffre, Murielle Gagneau, Anne Galinier, Jean-Noël Marzo, Fadi Meroueh","doi":"","DOIUrl":"","url":null,"abstract":"MANAGEMENT OF OPIATE ADDICTS: OBJECTIVE: To describe the social and medical profiles of incarcerated (in detention or after sentencing) opiate addicts, whether or not they had already begun substitution treatment at arrival, and assess the impact of high-dose buprenorphine substitution therapy on the health of prisoners and the course of their incarceration. METHODS: A prospective survey was conducted on opiate addicts on admission to prison and after 2 months of incarceration, from December 2001 to February 2003, in 6 prison centres in the South East of France. RESULTS: During incarceration, no significant difference (other than in medical follow-up) appeared between the prisoners receiving substitution treatment and those who went through withdrawal on arrival. The first group differed from the second in several respects: their occupational history before incarceration was less stable, their history of drug addiction and incarceration was more serious (injection, psychotropic use, number of prior incarcerations, early age at first incarceration). The buprenorphine patients also differed in their more intense use of medical follow-up before incarceration. CONCLUSION: The impact of buprenorphine substitution therapy during incarceration could not be demonstrated, but prisoners receiving this treatment had a substantially different profile than those who were not receiving treatment when they arrived in prison.","PeriodicalId":250357,"journal":{"name":"Presse Medicale (Paris, France : 1983)","volume":" ","pages":"487-490"},"PeriodicalIF":2.7,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40925802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Key points.] (要点)

IF 2.7

Presse Medicale (Paris, France : 1983) Pub Date : 2005-03-01

Valérie Delbos, Pierre Abgueguen, Serge Fanello, Olivier Brenet, Philippe Alquier, Jean-Claude Granry, E Ric Pichard

引用次数: 0

[Key points.] (要点)

IF 2.7

Presse Medicale (Paris, France : 1983) Pub Date : 2005-03-01

Valérie Delbos, Pierre Abgueguen, Serge Fanello, Olivier Brenet, Philippe Alquier, Jean-Claude Granry, E Ric Pichard

引用次数: 0

Réponse de Loïc Guillevin. loic Guillevin回答。