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New Ideas Concerning Science and Technology Vol. 11最新文献

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Investigating the Relationship between the Theoretical Layer Thickness of the Graphite Content of Lubricant and the Kudo’s Friction Number in the Case of Forged Parts 锻件中润滑油石墨含量理论层厚与工藤摩擦数关系的研究
New Ideas Concerning Science and Technology Vol. 11 Pub Date : 2021-04-16 DOI: 10.9734/BPI/NICST/V11/7759D
F. Tancsics
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引用次数: 0
Study on Pd(PPh3)4 Catalyzed Synthesis of Indazole Derivatives as Potent Anticancer Drug
New Ideas Concerning Science and Technology Vol. 11 Pub Date : 2020-05-29 DOI: 10.3390/app10113792
Jagan Mohana Rao Saketi, S. N. Murthy Boddapati, M. Raghuram, S. Adil, M. Shaik, O. Alduhaish, M. R. Siddiqui, H. Bollikolla
{"title":"Study on Pd(PPh3)4 Catalyzed Synthesis of Indazole Derivatives as Potent Anticancer Drug","authors":"Jagan Mohana Rao Saketi, S. N. Murthy Boddapati, M. Raghuram, S. Adil, M. Shaik, O. Alduhaish, M. R. Siddiqui, H. Bollikolla","doi":"10.3390/app10113792","DOIUrl":"https://doi.org/10.3390/app10113792","url":null,"abstract":"A series of 3-aryl indazoles and 1-methyl-3-aryl indazole derivatives are prepared with exceptional yields by coupling with several arylboronic acids and methylation by two dissimilar approaches. The as-prepared indazole derivatives (3a–3j) and their N-methyl derivatives (5a–5j) are evaluated for in vitro anticancer activity against two cancer cell lines, HCT-116 and MDA-MB-231. The results reveal that the indazole derivatives tested display mild to moderate anticancer activities against the cell lines tested.","PeriodicalId":248375,"journal":{"name":"New Ideas Concerning Science and Technology Vol. 11","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130922276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
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