Clinical Case Reports International最新文献

Systemic Lupus Erythematosus and Anti Phospholipid Syndrome in a Male Patient: A Case Report 一名男性患者的系统性红斑狼疮和抗磷脂综合征：病例报告

Clinical Case Reports International Pub Date : 2023-10-09 DOI: 10.25107/2638-4558-v7-id1614

Sawlani A, Masood R, Bai S, Anwar A

{"title":"Systemic Lupus Erythematosus and Anti Phospholipid Syndrome in a Male Patient: A Case Report","authors":"Sawlani A, Masood R, Bai S, Anwar A","doi":"10.25107/2638-4558-v7-id1614","DOIUrl":"https://doi.org/10.25107/2638-4558-v7-id1614","url":null,"abstract":"Abstract Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS) are two distinct autoimmune disorders characterized by dysregulated immune responses, organ involvement, and the presence of autoantibodies in the bloodstream. Primary Antiphospholipid Syndrome (APS) can occur among individuals who are generally healthy and have no history of an underlying systemic autoimmune illness. In contrast, several other systemic autoimmune diseases, including SLE, have the potential to cause secondary Antiphospholipid Syndrome (APS). While Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS) affect women of childbearing age, there are only a few reported case studies documenting the presence of SLE or APS individually in male patients. However, the coexistence of both conditions in a male patient is extremely rare, with only a few documented cases reports available to date. This case report presents a unique occurrence of concurrent SLE and APS in a forty-year-old male patient, highlighting the rarity of such a presentation. The patient presented with per rectal and mucosal bleeding and had been on warfarin therapy for 16 years due to a history of recurrent Deep Vein Thrombosis (DVT), but was not evaluated further. Immune-related laboratory results revealed positive antinuclear antibodies, anti-dsDNA antibodies, anticardiolipin antibodies, lupus anticoagulants, and direct Coombs test. Concurrent SLE and APS were diagnosed by meeting the classification criteria for both diseases. This report adds to the medical literature and emphasizes the significance of considering concurrent SLE and APS as a potential diagnosis in males. Further research is needed to enhance our understanding of the underlying mechanisms and the best approaches for managing this rare coexistence.","PeriodicalId":247189,"journal":{"name":"Clinical Case Reports International","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139321465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intestinal Adhesions and the Use of Dressings and Bio- Resorbable Membranes as Prevention and Treatment 肠粘连及敷料和生物可吸收膜的预防和治疗

Clinical Case Reports International Pub Date : 2023-04-24 DOI: 10.25107/2638-4558-v7-id1536

Sarah de O. Rodrigues, Rebecca de O. Rodrigues, Thiago de O. Rodrigues, Jorge P. Pagnossa

引用次数: 0

Salter-Harris Type 2 Fracture of Proximal Humerus Successfully Treated with K-Wire Fixation: A Case Report k针固定成功治疗肱骨近端Salter-Harris 2型骨折1例

Clinical Case Reports International Pub Date : 2023-03-21 DOI: 10.25107/2638-4558-v6-id1513

Cerchiaro M, Zanarella S, L. v, Ruggieri P

引用次数: 0

Central Nervous System Infections Associated with the SARS-CoV-2 Virus 与SARS-CoV-2病毒相关的中枢神经系统感染

Clinical Case Reports International Pub Date : 2022-12-15 DOI: 10.25107/2638-4558-v6-id1435

Ferreira Ab, A. As, Davis Vl, Diniz Cg, Cordeiro Dias V

引用次数: 0

Superior vena cava obstruction with thrombolytic therapy in primary antiphospholipid syndrome 原发性抗磷脂综合征的上腔静脉阻塞伴溶栓治疗

Clinical Case Reports International Pub Date : 2021-01-30 DOI: 10.22541/AU.161203349.96268572/V1

M. Adel, M. Mashaal, K. Mahmoud, S. Mashhour, H. Soliman

引用次数: 0

Case Report: An Off-label Use of the Air-filled Gastric Balloon System as an Adjunct to Bariatric Surgery 病例报告:在标签外使用充气胃球囊系统作为减肥手术的辅助手段

Clinical Case Reports International Pub Date : 2019-10-30 DOI: 10.25107/2638-4558-v3-id1121

Mai D. Gandhi, B. Welch, S. Luster, Noman Khan

引用次数: 0

Major Serological Screening Methodologies to Anti- T. Gondii Antibodies Detection in Pregnancy: Mini Literature View 妊娠期抗弓形虫抗体检测的主要血清学筛选方法:文献综述

Clinical Case Reports International Pub Date : 2018-10-13 DOI: 10.25107/CCRI-V2-ID1079

K. Bresciani, Lozano Tsp, Benitez Adn, Sakamoto, Romano Jfb, Stoppe Cv, J. M. Ferreira, Santos Jcd, Silva Tcc, J. Gomes

{"title":"Major Serological Screening Methodologies to Anti- T. Gondii Antibodies Detection in Pregnancy: Mini Literature View","authors":"K. Bresciani, Lozano Tsp, Benitez Adn, Sakamoto, Romano Jfb, Stoppe Cv, J. M. Ferreira, Santos Jcd, Silva Tcc, J. Gomes","doi":"10.25107/CCRI-V2-ID1079","DOIUrl":"https://doi.org/10.25107/CCRI-V2-ID1079","url":null,"abstract":"Congenital toxoplasmosis is a neglected protozoonotic disease of intercontinental distribution with incidence estimated in 1.5 cases per 1000 live births. This infection can be acquired intrauterine when the first infection of pregnant woman occurs and the Toxoplasma gondii reaches the fetus by transplacental via. The damage to the fetus can compromise the pregnancy and life quality of the infected individual. Early diagnosis of infection allows emergency therapeutic intervention with reduction of the transmission rate and also the severity of the sequelae. Different methodologies are available for the diagnosis of acute gestational toxoplasmosis with detection of IgG and IgM anti-T. gondii antibodies. The methodologies differ mainly by specificity and sensitivity values reached, as well as execution facility and time required. These parameters can decisively influence the choice of the most appropriate technique by the municipal health polices, in public health strategies. The main of the present review is to synthesize the major characteristics of serological tests for congenital toxoplasmosis.","PeriodicalId":247189,"journal":{"name":"Clinical Case Reports International","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121172390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0