F. Sanmarchi, Andrea Bucci, Andrea Giovanni Nuzzolese, G. Carullo, F. Toscano, N. Nante, D. Golinelli
{"title":"A step-by-step researcher's guide to the use of an AI-based transformer in epidemiology: an exploratory analysis of ChatGPT using the STROBE checklist for observational studies","authors":"F. Sanmarchi, Andrea Bucci, Andrea Giovanni Nuzzolese, G. Carullo, F. Toscano, N. Nante, D. Golinelli","doi":"10.1101/2023.02.06.23285514","DOIUrl":"https://doi.org/10.1101/2023.02.06.23285514","url":null,"abstract":"Objectives. This study aims at investigating how early-stage AI-based transformers can support researchers in designing and conducting an epidemiological study. To accomplish this, we used ChatGPT to reformulate the STROBE recommendations into a list of questions to be answered by the transformer itself. We then qualitatively evaluated the coherence and relevance of the transformers outputs. Study design: Descriptive study. Methods. We first chose a study to be used as a basis for the simulation. We then used ChatGPT to transform each STROBE checklist item into specific prompts. Each answer to the respective prompt was evaluated by independent researchers in terms of coherence and relevance. Results. The mean scores assigned to each prompt were heterogeneous. On average, for the coherence domain, the overall mean score was 3.6 out of 5.0, and for relevance it was 3.3 out of 5.0. The lowest scores were assigned to items belonging to the Methods section of the checklist. Conclusions. ChatGPT can be considered as a valuable support for researchers in conducting an epidemiological study, following internationally recognized guidelines and standards. It is crucial for the users to have knowledge on the subject and a critical mindset when evaluating the outputs. The potential benefits of AI in scientific research and publishing are undeniable, but it is crucial to address the risks, and the ethical and legal consequences associated with its use.","PeriodicalId":23839,"journal":{"name":"Zeitschrift Fur Gesundheitswissenschaften","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78431481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A qualitative analysis of facilitators and barriers to physical activity among patients with moderate mental disorders.","authors":"Denise van Rijen, Gill A Ten Hoor","doi":"10.1007/s10389-022-01720-4","DOIUrl":"10.1007/s10389-022-01720-4","url":null,"abstract":"<p><strong>Aim: </strong>The current study aims to qualitatively identify determinants, barriers and facilitators of physical activity among a population with mental health disorders.</p><p><strong>Subject and methods: </strong>Seventeen participants with moderate mental disorders were recruited. Semi-structured interviews were conducted to identify physical activity facilitators and barriers. Data were organized and analysed in ATLAS.ti, mainly based on a generic qualitative research approach.</p><p><strong>Results: </strong>Most participants found physical activity important and expressed a positive attitude towards it. In general, higher self-efficacy and more social support were beneficial for participants' physical activity levels. Reasons/facilitating factors to be more physically active were: having fun, good weather, progress, routine, self-compassion and a stimulating environment. Barriers were not having fun, being busy, mental complaints, lack of energy, procrastination and physical complaints.</p><p><strong>Conclusion: </strong>Future interventions could promote physical activity among people with moderate mental disorders to help them identify and overcome barriers. The newly identified determinant 'self-compassion' could be an interesting target for promoting physical activity in this group of people with moderate mental disorders.</p>","PeriodicalId":23839,"journal":{"name":"Zeitschrift Fur Gesundheitswissenschaften","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77856118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Linda Frost, Ruta Valaitis, Michelle Butt, Susan M Jack, Noori Akhtar-Danesh
{"title":"Influences on the uptake of a population health approach to sexual health programs in Ontario public health units: a qualitative descriptive study.","authors":"Linda Frost, Ruta Valaitis, Michelle Butt, Susan M Jack, Noori Akhtar-Danesh","doi":"10.1007/s10389-022-01715-1","DOIUrl":"10.1007/s10389-022-01715-1","url":null,"abstract":"<p><strong>Aim: </strong>Population-level prevention initiatives are the cornerstone of public health practice. However, despite this normative practice, sexual health programming within public health has not utilized this approach to the same extent as other public health programs. Understanding requirements to put a population-level approach into practice is needed. The objective of this study was to explore the barriers and facilitators experienced by sexual health programs and services within public health when implementing a population health approach.</p><p><strong>Subject design and methods: </strong>The principles of qualitative description guided all sampling, data collection and analysis decisions. Data collection involved in-depth semi-structured interviews with 12 sexual health managers and/or supervisors from ten Ontario public health units. Directed content analysis was used to code and synthesize the data. Data collection and analysis was guided using constructs from the Consolidated Framework for Implementation Research.</p><p><strong>Results: </strong>Factors that served as either barriers and facilitators to implementing a population health approach, were mainly in the inner and outer setting domains of the Consolidated Framework for Implementation Research. Participants identified the presence of community partnerships, adequate staff training on population health, and access to data on population health served as facilitators. In comparison, barriers to implementation included a lack of resources (human, financial) and clinicians' value of and preferences for delivering services at the individual clinic level.</p><p><strong>Conclusion: </strong>Some clear barriers and facilitators influenced if staff in sexual health programs and services could implement a population health approach. Results indicate where public health resources need to be enhanced to move toward a population health approach and provide insight into what worked and should be considered by public health organizations.</p>","PeriodicalId":23839,"journal":{"name":"Zeitschrift Fur Gesundheitswissenschaften","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79842243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors associated with the implementation of health-promoting telework from the perspective of company decision makers after the first COVID-19 lockdown","authors":"G. Lang, K. Hofer-Fischanger","doi":"10.1007/s10389-022-01717-z","DOIUrl":"https://doi.org/10.1007/s10389-022-01717-z","url":null,"abstract":"","PeriodicalId":23839,"journal":{"name":"Zeitschrift Fur Gesundheitswissenschaften","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72930257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Parchment, W. Lawrence, E. Rahman, N. Townsend, E. Wainwright, D. Wainwright
{"title":"How useful is the Making Every Contact Count Healthy Conversation Skills approach for supporting people with musculoskeletal conditions?","authors":"A. Parchment, W. Lawrence, E. Rahman, N. Townsend, E. Wainwright, D. Wainwright","doi":"10.1007/s10389-022-01718-y","DOIUrl":"https://doi.org/10.1007/s10389-022-01718-y","url":null,"abstract":"","PeriodicalId":23839,"journal":{"name":"Zeitschrift Fur Gesundheitswissenschaften","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87244586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Has the COVID-19 pandemic lockdown worsened eating disorders symptoms among patients with eating disorders? A systematic review","authors":"Yu-lin Gao, N. Bagheri, L. Furuya-Kanamori","doi":"10.1007/s10389-022-01704-4","DOIUrl":"https://doi.org/10.1007/s10389-022-01704-4","url":null,"abstract":"","PeriodicalId":23839,"journal":{"name":"Zeitschrift Fur Gesundheitswissenschaften","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76662135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Brailovskaia, Inga Truskauskaite-Kuneviciene, Evaldas Kazlauskas, Odeta Gelezelyte, Tobias Teismann, Jürgen Margraf
{"title":"Physical activity, mental and physical health during the Covid-19 outbreak: longitudinal predictors of suicide ideation in Germany.","authors":"Julia Brailovskaia, Inga Truskauskaite-Kuneviciene, Evaldas Kazlauskas, Odeta Gelezelyte, Tobias Teismann, Jürgen Margraf","doi":"10.1007/s10389-022-01708-0","DOIUrl":"10.1007/s10389-022-01708-0","url":null,"abstract":"<p><strong>Aim: </strong>Suicide ideation has increased since the outbreak of Covid-19 in many countries. The present longitudinal study investigated potential predictors of suicide ideation.</p><p><strong>Subject and methods: </strong>Data of 406 participants from Germany (age <i>M</i> = 27.69, <i>SD</i> = 6.88) were assessed via online surveys in spring 2020 (baseline, BL) and in spring 2021 (follow-up, FU).</p><p><strong>Results: </strong>The current results reveal a significant increase in symptoms of depression, anxiety, and stress between 2020 and 2021. Positive mental health (PMH), sense of control, and physical health significantly decreased. Depression symptoms (BL), PMH (BL), and consciously enhanced physical activity since the pandemic outbreak (FU) significantly predicted 12-month suicide ideation (FU). In a moderated mediation analysis, the positive relationship between depression and suicide ideation was significantly mediated by PMH. Consciously enhanced physical activity significantly moderated the negative association between PMH and suicide ideation.</p><p><strong>Conclusion: </strong>The context of Covid-19 could negatively impact mental health and physical health. This might increase the risk for suicide ideation. However, PMH and physical activity might serve as protective factors. The protective effect of physical activity could be especially important in people with high depression symptoms and low PMH, such as clinical patients. Potential ways of how PMH and physical activity could be enhanced in the Covid-19 context to prevent suicide ideation are discussed.</p>","PeriodicalId":23839,"journal":{"name":"Zeitschrift Fur Gesundheitswissenschaften","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76418445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Johannes Beller, Jürgen Schäfers, Jörg Haier, Siegfried Geyer, Jelena Epping
{"title":"Trust in Healthcare during COVID-19 in Europe: vulnerable groups trust the least.","authors":"Johannes Beller, Jürgen Schäfers, Jörg Haier, Siegfried Geyer, Jelena Epping","doi":"10.1007/s10389-022-01705-3","DOIUrl":"10.1007/s10389-022-01705-3","url":null,"abstract":"<p><strong>Aim: </strong>We examined predictors of trust in the healthcare system during the COVID-19 pandemic in 27 European countries.</p><p><strong>Subjects and methods: </strong>We used population-based data drawn from the Living, working and COVID-19 survey (<i>N</i> = 21,884, 52% female, ages 18 to 92 years) covering 27 European countries dated June and July 2020. Multilevel linear regression, linear regression, and regression-tree analyses were conducted.</p><p><strong>Results: </strong>We found that most participants tended to trust the healthcare system, although a substantial part could still be classified as distrusting (approx. 21%). Multiple variables, including being middle-aged or of older age, being female, lower levels of education, unemployment, worse general health status, having income difficulties, having unmet needs for healthcare, no healthcare contact during the COVID-19 pandemic, higher mental distress, and loneliness, were significantly associated with lower levels of trust. Among these variables mental distress, income difficulties, and unmet needs for healthcare emerged as especially important and, across European regions and countries, consistent predictors for lower trust in the healthcare system during the COVID-19 pandemic.</p><p><strong>Conclusions: </strong>Medically vulnerable subgroups, such as individuals with unmet healthcare needs, higher levels of mental distress, and older age, as well as people living in socially and economically vulnerable situations, such as higher levels of loneliness and financial difficulties, were the least trusting of the healthcare system during the COVID-19 pandemic. As these vulnerable subgroups are also at highest risk for contracting COVID-19 and experiencing negative COVID-19-related outcomes, more targeted prevention and intervention efforts should be implemented in these groups.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s10389-022-01705-3.</p>","PeriodicalId":23839,"journal":{"name":"Zeitschrift Fur Gesundheitswissenschaften","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82864888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of approved vaccines to prevent COVID-19: a systematic review and network meta-analysis of reconstructed individual patient data from randomized trials.","authors":"Alhassane Diallo, Miguel Carlos-Bolumbu, Mamadou Hassimiou Diallo, Alain Makinson, Florence Galtier","doi":"10.1007/s10389-022-01707-1","DOIUrl":"10.1007/s10389-022-01707-1","url":null,"abstract":"<p><strong>Aim: </strong>To optimize vaccination strategy, evidence on vaccine efficacy against COVID-19 is needed.</p><p><strong>Method: </strong>The present network meta-analysis uses reconstructed individual patient data from phase III trials on vaccine efficacy (VE), identified through MEDLINE, EMBASE, and Cochrane library (CENTRAL) peer-reviewed and published in English before August 31, 2021. The primary outcome was the VE against confirmed COVID-19 at any time after the first dose as defined in each study. VE was re-estimated using the two-stage approach. Poisson regression models were applied to each trial at the first stage, and the incidence risk ratio (IRR) and their 95% CI were aggregated to allow random-effects network meta-analysis (NMA) at the second stage. VE was expressed as: (1-IRR) × 100. The study protocol is registered in PROSPERO (CRD42020200012).</p><p><strong>Results: </strong>A total of eight studies, evaluating nine different vaccines were identified and analyzed. Between April 23, 2020 and January 05, 2021, 210,418 participants were recruited in 354 sites worldwide. During a median (IQR) follow-up duration of 69.8 (69.7-70.3) days, 2131 confirmed COVID-19 cases occurred (604; 26.0 per 1000 person-years in vaccine recipients and 1527; 85.9 per 1000 person-years in the control group). The mRNA-1273 vaccine was the most effective (P-score 0.99); at any time after dose 1, incidence reduction for mRNA-1273 ranged from 78% to 98% compared to the other vaccines.</p><p><strong>Conclusion: </strong>Our results provide evidence for the short-term superiority of mRNA vaccines, especially the mRNA-1273 vaccine in prevention of COVID-19 in different populations.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s10389-022-01707-1.</p>","PeriodicalId":23839,"journal":{"name":"Zeitschrift Fur Gesundheitswissenschaften","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76246861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ulrich Marcus, Daniel Schmidt, Susanne B Schink, Uwe Koppe
{"title":"Analysis of HIV pre-exposure prophylaxis (PrEP) needs and PrEP use in Germany among men who have sex with men.","authors":"Ulrich Marcus, Daniel Schmidt, Susanne B Schink, Uwe Koppe","doi":"10.1007/s10389-022-01699-y","DOIUrl":"10.1007/s10389-022-01699-y","url":null,"abstract":"<p><strong>Aims: </strong>We aim to estimate the number of HIV pre-exposure prophylaxis (PrEP) users among men having sex with men (MSM) in Germany from 2017 through 2020, and analyse if PrEP needs expressed in 2017 might have been met by the expansion of PrEP until 2020.</p><p><strong>Subject and methods: </strong>We estimated the number of PrEP users by using drug prescription data and information on on-demand/intermittent PrEP use from online surveys to determine the proportion of on-demand/intermittent and daily PrEP use as well as the average number of PrEP pills used.The number of MSM in need of PrEP in 2017 was estimated based on four groups defined among respondents to a large online survey, combining respondents with PrEP use intention and respondents indicating substantial sexual risks. The size of each group was estimated based on self-selection biases. MSM with PrEP need in 2017 were compared with the estimated number of persons taking PrEP by June 2020.</p><p><strong>Results: </strong>We estimated a total of 15,600 to 21,600 PrEP users in Germany by the end of June 2020, corresponding to 40-55% of men with PrEP use intention in 2017. A correlation between the regional distribution of PrEP use intention in 11/2017 and actual PrEP use by 06/2020 suggested an unequal regional distribution of unsatisfied needs. The number of men with unmet PrEP needs ranged between 27,500 and 93,000 in 06/2020.</p><p><strong>Conclusion: </strong>PrEP use in Germany has increased considerably between 10/2017 and 06/2020, but large regional inequalities persist. PrEP is not yet readily accessible, and there is a need to expand services and encourage uptake.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s10389-022-01699-y.</p>","PeriodicalId":23839,"journal":{"name":"Zeitschrift Fur Gesundheitswissenschaften","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78184279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}