M. Cook, M. Lunt, D. Ashcroft, T. Board, T. O’Neill
{"title":"The Impact of Frailty and Deprivation on the Likelihood of Receiving Primary Total Hip and Knee Arthroplasty among People with Hip and Knee Osteoarthritis","authors":"M. Cook, M. Lunt, D. Ashcroft, T. Board, T. O’Neill","doi":"10.14283/jfa.2023.36","DOIUrl":"https://doi.org/10.14283/jfa.2023.36","url":null,"abstract":"Among people with hip and knee osteoarthritis (OA), increasing deprivation is associated with reduced likelihood of receiving hip and knee arthroplasty (THA, TKA). To assess whether higher levels of frailty in the most deprived neighbourhoods explains the association between greater neighbourhood deprivation and reduced likelihood of receiving THA and TKA among people with hip and knee OA. Longitudinal cohort study. Linked primary and secondary care electronic medical records and national mortality data. 104,913 individuals with incident hip OA and 216,420 with incident knee OA. Frailty was assessed using a frailty index and categorised as fit, mild, moderate, and severe frailty. Neighbourhood deprivation was assessed using the index of multiple deprivation (IMD). Compared to those in neighbourhoods in the least deprived quintile of IMD, those in neighbourhoods in the fourth and fifth quintile of IMD (most deprived), respectively, were less likely to receive THA, adjusted subhazard ratio (95% CI), 0.90 (0.87, 0.93) and 0.77 (0.74, 0.80), over a mean follow up of 4.4 years, with similar results for TKA. Higher levels of frailty at OA diagnosis were associated also with reduced likelihood of receiving THA and TKA. The association, however, between deprivation and likelihood of receiving THA and TKA could not be explained by increased levels of frailty among those living in the most deprived areas. Further work is needed to understand why those in the most deprived areas are less likely to receive THA and TKA.","PeriodicalId":236960,"journal":{"name":"Journal of Frailty & Aging","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131432570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Ahip, O. Theou, S. Shariff-Ghazali, A. Samad, S. Lukas, U. Mustapha, R. Visvanathan
{"title":"The Pictorial Fit-Frail Scale Malay Version (PFFS-M): Predictive Validity Testing in Malaysian Primary Care","authors":"S. Ahip, O. Theou, S. Shariff-Ghazali, A. Samad, S. Lukas, U. Mustapha, R. Visvanathan","doi":"10.14283/jfa.2023.35","DOIUrl":"https://doi.org/10.14283/jfa.2023.35","url":null,"abstract":"","PeriodicalId":236960,"journal":{"name":"Journal of Frailty & Aging","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130432897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. L. Sáez de Asteasu, E. Cadore, T. Steffens, E. Blanco-Rambo, T.C. Schneider, M. Izquierdo, C. Pietta-Dias
{"title":"Reduced Handgrip Strength Is Associated with 1 Year-Mortality in Brazilian Frail Nonagenarians and Centenarians","authors":"M. L. Sáez de Asteasu, E. Cadore, T. Steffens, E. Blanco-Rambo, T.C. Schneider, M. Izquierdo, C. Pietta-Dias","doi":"10.14283/jfa.2023.21","DOIUrl":"https://doi.org/10.14283/jfa.2023.21","url":null,"abstract":"","PeriodicalId":236960,"journal":{"name":"Journal of Frailty & Aging","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123385845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Bellelli, E. Consorti, T.M.K. Hettiarachchige, P. Rossi, T. Lucchi, M. Froldi, M. Cesari
{"title":"Relationship among Age, Education and Frailty in Older Persons","authors":"F. Bellelli, E. Consorti, T.M.K. Hettiarachchige, P. Rossi, T. Lucchi, M. Froldi, M. Cesari","doi":"10.14283/jfa.2023.39","DOIUrl":"https://doi.org/10.14283/jfa.2023.39","url":null,"abstract":"Preliminary data suggest that frailty tend to increase with age and is associated with fewer years of formal education. However, it is still unclear whether age and education synergistically act in the definition of frailty. Aim of the study is to evaluate the interaction between age and education in defining frailty in community-dwelling older persons. We considered 911 community-dwelling older adults (mean age 79.5 years) who underwent a comprehensive geriatric assessment. Our results showed that education and age interact in the definition of frailty following an exponential-type relationship. Whereas age is a non-modifiable risk factor, much can be done to address the social component of frailty here represented by education. The reported interaction suggests that social interventions might be particularly effective at an older age, paving the way for multidisciplinary interventions beyond the clinical field.","PeriodicalId":236960,"journal":{"name":"Journal of Frailty & Aging","volume":"284 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122727721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Association of Bone Turnover Markers with Muscle Function, Falls, and Frailty in Older Women in Long-Term Care","authors":"N.S. Haeri, S. Perera, S.L. Greenspan","doi":"10.14283/jfa.2023.38","DOIUrl":"https://doi.org/10.14283/jfa.2023.38","url":null,"abstract":"Osteoporosis and sarcopenia commonly coexist in older adults. There is strong evidence that bone and muscle impact each other through mechanical and biochemical cross-talk. We sought to investigate the relationship between the markers of bone remodeling including the C-terminal telopeptide of type 1 collagen (CTX) and procollagen type 1 N propeptide (P1NP) with muscle function, falls, and frailty in older women residing in long-term care (LTC) facilities. A secondary analysis of a randomized controlled trial. Residents of LTC. One hundred seventy-eight older women with osteoporosis. We measured and analyzed baseline CTX, P1NP, gait speed, sit to stand time, history of falls, and frailty index. Participants had a mean age of 86.7 years and BMI of 27.6 kg/m2. The correlation (r) of CTX with gait speed and sit to stand test, as indices for muscle function, were −0.193 (p=0.0163) and 0.152 (p=0.0507), respectively. Additionally, CTX level was significantly associated with history of falls (p=0.0068), recurrent falls (p=0.0260), and frail phenotype (p=0.0126). P1NP did not have a significant association with gait speed, sit to stand test, and history of falls; however, it was associated with frail phenotype (p=0.0137). Most findings persisted after adjusting for age. In older women residing in LTC facilities, CTX was associated with gait speed, falls history, and frail phenotype, whereas P1NP was only associated with frail phenotype. These findings suggest a relationship between bone remodeling and muscle function.","PeriodicalId":236960,"journal":{"name":"Journal of Frailty & Aging","volume":"140 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116482120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}