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C19. EMERGING MECHANISMS IN COPD AND ASTHMA最新文献

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Single Cell RNA Sequencing Identifies Dysfunctional Alveolar Type II Subsets Derived by Club Cells in Chronic Obstructive Pulmonary Disease 单细胞RNA测序鉴定慢性阻塞性肺疾病中俱乐部细胞衍生的功能失调肺泡II型亚群
C19. EMERGING MECHANISMS IN COPD AND ASTHMA Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4529
Y. Hu, Q. Hu, K. Riemondy, M. Ansari, B. Gao, W. Janssen, H. Schiller, C. Evans, M. Koenigshoff
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引用次数: 0
Early COPD Risk Is Associated With Decreased Airway Basal Progenitor Function and Altered Cellular Bioenergetics in Younger Smokers 年轻吸烟者早期COPD风险与气道基础祖细胞功能降低和细胞生物能量学改变有关
C19. EMERGING MECHANISMS IN COPD AND ASTHMA Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4534
K. Lkhagvadorj, K. Kincaid, H. Kim, S. Rangarajan, P. Londoño, J.R. Haines, H. Chu, K. Schweitzer, I. Petrache, Y. Miller, R. Vandivier, M. Ghosh
{"title":"Early COPD Risk Is Associated With Decreased Airway Basal Progenitor Function and Altered Cellular Bioenergetics in Younger Smokers","authors":"K. Lkhagvadorj, K. Kincaid, H. Kim, S. Rangarajan, P. Londoño, J.R. Haines, H. Chu, K. Schweitzer, I. Petrache, Y. Miller, R. Vandivier, M. Ghosh","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4534","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4534","url":null,"abstract":"","PeriodicalId":236341,"journal":{"name":"C19. EMERGING MECHANISMS IN COPD AND ASTHMA","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114989876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Steroid-resistant Severe Asthma and Fatal Asthma Small Airways Are Defined by Mucus Plugging and Heterogeneous MUC5AC Expression 黏液堵塞和MUC5AC异质表达定义了类固醇抵抗性重度哮喘和致死性哮喘小气道
C19. EMERGING MECHANISMS IN COPD AND ASTHMA Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4535
S. Schworer, K. Okuda, H. Dang, T. Kato, G. Chen, R. Gilmore, M. Chua, H. T. Trejo Bittar, B. Cody, J. Trudeau, W. O'Neal, S. Randell, S. Wenzel, R. C. Boucher
{"title":"Steroid-resistant Severe Asthma and Fatal Asthma Small Airways Are Defined by Mucus Plugging and Heterogeneous MUC5AC Expression","authors":"S. Schworer, K. Okuda, H. Dang, T. Kato, G. Chen, R. Gilmore, M. Chua, H. T. Trejo Bittar, B. Cody, J. Trudeau, W. O'Neal, S. Randell, S. Wenzel, R. C. Boucher","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4535","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4535","url":null,"abstract":"","PeriodicalId":236341,"journal":{"name":"C19. EMERGING MECHANISMS IN COPD AND ASTHMA","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116573023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loss of P73 Is Common in Chronic Obstructive Pulmonary Disease Small Airways, Is Induced by Cigarette Smoke, and Contributes to Emphysema P73的丧失在慢性阻塞性肺疾病小气道中很常见，是由吸烟引起的，并有助于肺气肿
C19. EMERGING MECHANISMS IN COPD AND ASTHMA Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4531
B. Richmond, C. Marshall, Y. Liu, B. Lehmann, T. Tufenkjian, J. B. Blackburn, P. Hunt, V. Polosukhin, T. Blackwell, J. Pietenpol
{"title":"Loss of P73 Is Common in Chronic Obstructive Pulmonary Disease Small Airways, Is Induced by Cigarette Smoke, and Contributes to Emphysema","authors":"B. Richmond, C. Marshall, Y. Liu, B. Lehmann, T. Tufenkjian, J. B. Blackburn, P. Hunt, V. Polosukhin, T. Blackwell, J. Pietenpol","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4531","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4531","url":null,"abstract":"","PeriodicalId":236341,"journal":{"name":"C19. EMERGING MECHANISMS IN COPD AND ASTHMA","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133702049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cellular and Molecular Mechanisms Underlying FGF10-mediated Reversion of Experimental Emphysema and Pulmonary Hypertension in Mice fgf10介导小鼠实验性肺气肿和肺动脉高压逆转的细胞和分子机制
C19. EMERGING MECHANISMS IN COPD AND ASTHMA Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4532
S. Hadzic, E. Loku, C.‐y. Wu, M. Gredic, O. Pak, J. Wilhelm, B. Kojonazarov, A. Guenther, N. Sommer, F. Grimminger, H. Ghofrani, R. Schermuly, W. Seeger, E. El-Agha, S. Bellusci, N. Weissmann
{"title":"Cellular and Molecular Mechanisms Underlying FGF10-mediated Reversion of Experimental Emphysema and Pulmonary Hypertension in Mice","authors":"S. Hadzic, E. Loku, C.‐y. Wu, M. Gredic, O. Pak, J. Wilhelm, B. Kojonazarov, A. Guenther, N. Sommer, F. Grimminger, H. Ghofrani, R. Schermuly, W. Seeger, E. El-Agha, S. Bellusci, N. Weissmann","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4532","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4532","url":null,"abstract":"","PeriodicalId":236341,"journal":{"name":"C19. EMERGING MECHANISMS IN COPD AND ASTHMA","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132853062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loss of CD55 in Alveolar Type 2 Epithelial (AT2) Cells Results in Decreased Cell Proliferation and Increased Lung Complement Deposition During Cigarette Smoking 吸烟时肺泡2型上皮(AT2)细胞中CD55的缺失导致细胞增殖减少和肺补体沉积增加
C19. EMERGING MECHANISMS IN COPD AND ASTHMA Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4530
E. Lundberg, I. Echelman, K. Duvall, H. Jacobs, T. Miwa, W. Song, I. Petrache, J. Matsuda, J. Bridges, K. Serban
{"title":"Loss of CD55 in Alveolar Type 2 Epithelial (AT2) Cells Results in Decreased Cell Proliferation and Increased Lung Complement Deposition During Cigarette Smoking","authors":"E. Lundberg, I. Echelman, K. Duvall, H. Jacobs, T. Miwa, W. Song, I. Petrache, J. Matsuda, J. Bridges, K. Serban","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4530","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4530","url":null,"abstract":"","PeriodicalId":236341,"journal":{"name":"C19. EMERGING MECHANISMS IN COPD AND ASTHMA","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129793018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitochondrial Adenine Nucleotide Translocase 2 (Ant2) Regulates Alveolar Epithelial Cell Senescence and Repair in COPD 线粒体腺嘌呤核苷酸转位酶2 (Ant2)调节COPD肺泡上皮细胞衰老和修复
C19. EMERGING MECHANISMS IN COPD AND ASTHMA Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4537
C. Kliment, J. Sui, I. Walsh, N. Oury, J. Shi, Q. Hu, M. Koenigshoff
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引用次数: 0
Gene Environment Interaction in Chronic Obstructive Pulmonary Disease: Involvement of a Nicotinic Receptor Gene Polymorphism 慢性阻塞性肺疾病的基因环境相互作用:烟碱受体基因多态性的参与
C19. EMERGING MECHANISMS IN COPD AND ASTHMA Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4533
L. Massara, G. Kervoaze, A. Ollivier, M. Pichavant, L. Saber Cherif, S. Pons, U. Maskos, V.C.R. Dormoy, P. Gosset
{"title":"Gene Environment Interaction in Chronic Obstructive Pulmonary Disease: Involvement of a Nicotinic Receptor Gene Polymorphism","authors":"L. Massara, G. Kervoaze, A. Ollivier, M. Pichavant, L. Saber Cherif, S. Pons, U. Maskos, V.C.R. Dormoy, P. Gosset","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4533","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4533","url":null,"abstract":"","PeriodicalId":236341,"journal":{"name":"C19. EMERGING MECHANISMS IN COPD AND ASTHMA","volume":"53 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123253497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single-cell Transcriptomic Analysis Reveals an Altered Bronchial Epithelial Cell Differentiation in Asthma 单细胞转录组学分析揭示哮喘支气管上皮细胞分化的改变
C19. EMERGING MECHANISMS IN COPD AND ASTHMA Pub Date : 2023-03-09 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4536
Aurore C. A. Gay, B. Doddema, T.E. Gillet, M. Khan, T. Kole, L. Apperloo, M. Banchero, M. van den Berge, M. Nawijn
{"title":"Single-cell Transcriptomic Analysis Reveals an Altered Bronchial Epithelial Cell Differentiation in Asthma","authors":"Aurore C. A. Gay, B. Doddema, T.E. Gillet, M. Khan, T. Kole, L. Apperloo, M. Banchero, M. van den Berge, M. Nawijn","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4536","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4536","url":null,"abstract":"","PeriodicalId":236341,"journal":{"name":"C19. EMERGING MECHANISMS IN COPD AND ASTHMA","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134172217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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