Atherosclerosis, Arteriosclerosis and Arteriolosclerosis最新文献

Carotid Disease 颈动脉疾病

Atherosclerosis, Arteriosclerosis and Arteriolosclerosis Pub Date : 2020-05-20 DOI: 10.5772/intechopen.90408

Minerva Irene Hernández Rejón, Manuel Alexis Vargas Robles

引用次数: 0

Introductory Chapter: Atherosclerosis, Arteriosclerosis, and Arteriolosclerosis 导论章:动脉粥样硬化、动脉硬化和动脉硬化

Atherosclerosis, Arteriosclerosis and Arteriolosclerosis Pub Date : 2020-05-20 DOI: 10.5772/intechopen.92132

L. Gianturco

引用次数: 0

Coronary Atherosclerosis in Women 女性冠状动脉粥样硬化

Atherosclerosis, Arteriosclerosis and Arteriolosclerosis Pub Date : 2020-03-26 DOI: 10.5772/INTECHOPEN.90628

Abhishek Ojha, Nishtha Sareen

{"title":"Coronary Atherosclerosis in Women","authors":"Abhishek Ojha, Nishtha Sareen","doi":"10.5772/INTECHOPEN.90628","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.90628","url":null,"abstract":"Despite numerous studies focused on women’s cardiac health, deaths from cardiovascular disease continue to rise in women. Cardiovascular disease (CVD) continues to be the leading cause of death even in women in many areas of the world. It has been noted that despite higher frequency of chest pain/angina in women compared to men, the incidence of obstructive coronary artery disease (CAD) remains lower in the female population compared with men presenting with similar symptoms. It is critical to have a deep understanding of these topics to ensure a meaningful communication between public, patients, and healthcare professionals. One reason to which this discrepancy has been attributed to is that chest pain in women is less likely to be secondary to obstructive coronary stenosis in comparison to men presenting with similar symptoms. The other issue is that the gold standard for coronary atherosclerosis continues to coronary angiography. This is a key limitation in cardiovascular atherosclerosis management since endothelial dysfunction in addition to a higher risk of atherosclerosis is prevalent in women with hypertension, diabetes, and dyslipidemia. In this chapter, we will focus on the aspects of coronary atherosclerosis that deserve attention with respect to gender-specific considerations, particularly with respect to clinical practice.","PeriodicalId":232678,"journal":{"name":"Atherosclerosis, Arteriosclerosis and Arteriolosclerosis","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127945096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atherosclerosis: A Journey around the Terminology 动脉粥样硬化:术语之旅

Atherosclerosis, Arteriosclerosis and Arteriolosclerosis Pub Date : 2020-02-12 DOI: 10.5772/intechopen.91064

O. Adebayo, A. Adeoye

引用次数: 2

Atherosclerosis in Rheumatology: Old and New Insights 风湿病学中的动脉粥样硬化:新旧见解

Atherosclerosis, Arteriosclerosis and Arteriolosclerosis Pub Date : 2019-08-14 DOI: 10.5772/INTECHOPEN.88605

S. Oreská, M. Tomčík

{"title":"Atherosclerosis in Rheumatology: Old and New Insights","authors":"S. Oreská, M. Tomčík","doi":"10.5772/INTECHOPEN.88605","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.88605","url":null,"abstract":"Cardiovascular diseases are the leading cause of morbidity and mortality in general population worldwide. There is an increasing significance of cardiovascular risk in the field of rheumatology, and accordingly, the evidence on the relation between immune system disorders and atherosclerosis has been substantially growing especially in last decades. Since novel immune and metabolic factors are considered to participate in pathogenesis of atherosclerosis and increased cardiovascular risk in rheumatic patients, they are getting to the forefront of the research. Since novel therapeutic approaches have improved survival of rheumatic patients, and decreased morbidity caused by rheumatic disease activity and damage, the significance of other comorbidities leading to premature mortality has arisen. Nevertheless, appropriate recommendations for the management of cardiovascular risk are still lacking. Recently, European League Against Rheumatism (EULAR) recommendations for management of the cardiovascular risk and comorbidities in patients with inflammatory arthropathies have been published. However, the cardiovascular management of these patients is still suboptimal. In addition, the situation in other orphan diseases such as idiopathic inflammatory myopathies, systemic sclerosis and others is even more uncertain and strongly requires further research. This chapter provides an overview of epidemiology, pathogenesis, clinical manifestations, screening and management of atherosclerosis in patients with rheumatic diseases.","PeriodicalId":232678,"journal":{"name":"Atherosclerosis, Arteriosclerosis and Arteriolosclerosis","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133786160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intermittent Hypoxia and Obstructive Sleep Apnea: Mechanisms, Interindividual Responses and Clinical Insights 间歇性缺氧和阻塞性睡眠呼吸暂停:机制，个体间反应和临床见解

Atherosclerosis, Arteriosclerosis and Arteriolosclerosis Pub Date : 2019-04-26 DOI: 10.5772/INTECHOPEN.86117

L. Lavie

{"title":"Intermittent Hypoxia and Obstructive Sleep Apnea: Mechanisms, Interindividual Responses and Clinical Insights","authors":"L. Lavie","doi":"10.5772/INTECHOPEN.86117","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.86117","url":null,"abstract":"Obstructive sleep apnea (OSA), a nightly respiratory condition, is characterized by recurrent upper airway collapse causing intermittent hypoxia (IH) resembling ischemia and reperfusion (I/R). Consequently, blood oxygenation levels are cyclically reduced; sleep fragmentation and sympathetic activation develop, thus invoking oxidative stress and inflammation. OSA is a major risk factor for cardio-/ cerebrovascular morbidity and mortality. However, not all OSA patients develop cardio-/cerebrovascular disease, even if suffering from similar OSA severity. Possibly, this results from interindividual differences in responses to a given hypoxic stimulus involving gene polymorphism in oxygen-regulated transcription factors and downstream genes. The current review is aimed at highlighting potentially protective mechanisms induced by IH and OSA, rather than its well-estab-lished deleterious effects, while focusing on acute coronary syndromes. Therefore, protective mechanisms revealed in I/R biology and exhibited in vitro and in animal models utilizing IH followed by a severe ischemia are discussed and linked to acute myocardial infarction patients with concomitant OSA. The roles of endothelial progenitor cells, their proliferative and angiogenic properties, and collateral formation are emphasized in the clinical setting, as well as heterogenic interindividual responses to identical hypoxic stimuli. These findings might represent potential predictors to cardio-/cerebrovascular health, by identifying patients at higher or lower cardiovascular risk.","PeriodicalId":232678,"journal":{"name":"Atherosclerosis, Arteriosclerosis and Arteriolosclerosis","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132852156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7