{"title":"S102 The under recognised role of moderate eosinophilia on exacerbation frequency in COPD patients: a single centre study","authors":"P. Dobson, A. Dewar","doi":"10.1136/thorax-2021-btsabstracts.108","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.108","url":null,"abstract":"","PeriodicalId":215643,"journal":{"name":"Ease that wheeze: managing risk in COPD","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123345553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Müllerová, Z. Marjenberg, J. Marshall, E. de Nigris, P. Varghese, N. Pooley, N. Embleton
{"title":"S100 Risk of cardiovascular morbidity and mortality in people with chronic obstructive pulmonary disease versus those without COPD: A structured review of the evidence","authors":"H. Müllerová, Z. Marjenberg, J. Marshall, E. de Nigris, P. Varghese, N. Pooley, N. Embleton","doi":"10.1136/thorax-2021-btsabstracts.106","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.106","url":null,"abstract":"of a novel fibre-based FLIM which utilises 488nm excitation to enable fluorescence intensity and lifetime imaging, to detect changes in freshly resected lung cancer and adjacent healthy tissue. The mechanisms responsible for altera-tions in lung cancer fluorescence lifetime are not understood. We investigate the contributions of cancer cells and tumour stroma to fluorescence lifetime signatures using fixed unstained lung cancer and benchtop FLIM. different timepoints, between 2 hours and 1 year from presentation. in the instruments used to evaluate treatment or failure in COPD exacerbation trials. Standardization could promote comparability.","PeriodicalId":215643,"journal":{"name":"Ease that wheeze: managing risk in COPD","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132730468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Mathioudakis, S. Ananth, T. Bradbury, B. Csoma, G. Fernandez Romero, G. Criner, C. Jenkins, P. Williamson, J. Jensen, J. Vestbo
{"title":"S101 Methods for assessing the success or failure of COPD exacerbation treatments in therapeutic clinical trials: A meta-epidemiological systematic review","authors":"A. Mathioudakis, S. Ananth, T. Bradbury, B. Csoma, G. Fernandez Romero, G. Criner, C. Jenkins, P. Williamson, J. Jensen, J. Vestbo","doi":"10.1136/thorax-2021-btsabstracts.107","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.107","url":null,"abstract":"","PeriodicalId":215643,"journal":{"name":"Ease that wheeze: managing risk in COPD","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115761882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"S103 The provision of the five fundamentals of COPD care – findings from a UK-wide survey of people with COPD","authors":"A. Cumella, A. Cook","doi":"10.1136/thorax-2021-btsabstracts.109","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.109","url":null,"abstract":"","PeriodicalId":215643,"journal":{"name":"Ease that wheeze: managing risk in COPD","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114639729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. de Nigris, U. Holmgren, C. Treharne, N. Brighton, A. Walker, J. Haughney
{"title":"S104 Cost-effectiveness of triple therapy with budesonide/glycopyrronium/formoterol fumarate versus dual therapies in moderate-to-very severe COPD in the United Kingdom: analysis based on the KRONOS study","authors":"E. de Nigris, U. Holmgren, C. Treharne, N. Brighton, A. Walker, J. Haughney","doi":"10.1136/thorax-2021-btsabstracts.110","DOIUrl":"https://doi.org/10.1136/thorax-2021-btsabstracts.110","url":null,"abstract":"","PeriodicalId":215643,"journal":{"name":"Ease that wheeze: managing risk in COPD","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133650026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}