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Effect of holder pasteurization and storage of donor human milk on Bacillus cereus survival 供体母乳的支架巴氏杀菌和储存对蜡样芽孢杆菌存活率的影响

Postępy Higieny i Medycyny Doświadczalnej Pub Date : 2024-01-01 DOI: 10.2478/ahem-2023-0027

Kamila Strom, S. Jarzynka, Anna Minkiewicz-Zochniak, A. Wesołowska, G. Olędzka

{"title":"Effect of holder pasteurization and storage of donor human milk on Bacillus cereus survival","authors":"Kamila Strom, S. Jarzynka, Anna Minkiewicz-Zochniak, A. Wesołowska, G. Olędzka","doi":"10.2478/ahem-2023-0027","DOIUrl":"https://doi.org/10.2478/ahem-2023-0027","url":null,"abstract":"\u0000 \u0000 \u0000 Human milk, which constitutes the best composed nutrition for infants, is not a sterile biofluid. Besides nutritional and bioactive components, many microorganisms have been found in human milk, including Bacillus cereus. Those pathogenic bacteria can be responsible for causing pneumonia or septicemia in neonates. Although Bacillus cereus infections are not common, they represent one of the increasing factors of a high mortality rate in the preterm infants group. Donor human milk (DHM) may be a significant source of this pathogen.\u0000 \u0000 \u0000 \u0000 Given the high ability of Bacillus cereus spores to survive under different thermal conditions, we tested the effect of the holder pasteurization and storage points (4 °C and −21 °C) on sporulation and vegetative forms’ survival in inoculated human milk samples by culture method and light microscopy.\u0000 \u0000 \u0000 \u0000 Studies confirmed that holder pasteurization is effective against vegetative forms of Bacillus cereus. Additionally, during storage endospores were observed in all analyzed inoculated donor milk samples, both the pasteurized and unpasteurized samples, thus possibly promoting the occurrence of Bacillus cereus in DHM.\u0000 \u0000 \u0000 \u0000 \u0000 Bacillus cereus is considered a contamination in DHM and in the human milk banks’ (HMB) environment. There is a need to further develop methods of identifying, transmitting, and preventing bacteria forming spores, which could be applied in HMB.\u0000","PeriodicalId":20344,"journal":{"name":"Postępy Higieny i Medycyny Doświadczalnej","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140525358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ocular ischemic syndrome – case report and literature analysis 眼缺血综合征--病例报告和文献分析

Postępy Higieny i Medycyny Doświadczalnej Pub Date : 2024-01-01 DOI: 10.2478/ahem-2024-0001

Aleksandra Górska, Marek Sosnowski, Sebastian Sirek, R. Leszczyński, Mikołaj Kuźniak, Ewa Mrukwa-Kominek

{"title":"Ocular ischemic syndrome – case report and literature analysis","authors":"Aleksandra Górska, Marek Sosnowski, Sebastian Sirek, R. Leszczyński, Mikołaj Kuźniak, Ewa Mrukwa-Kominek","doi":"10.2478/ahem-2024-0001","DOIUrl":"https://doi.org/10.2478/ahem-2024-0001","url":null,"abstract":"\u0000 \u0000 \u0000 Ocular ischemic syndrome (OIS) is a rare condition associated with ocular hypoperfusion caused by carotid artery occlusive disease. This article describes the case of a patient who was admitted to the Department of Ophthalmology at UCK in Katowice, Poland, due to significant loss of visual acuity and pain in the right eye.\u0000 \u0000 \u0000 \u0000 Retrosopective case report.\u0000 \u0000 \u0000 \u0000 Patient showed up in the ophthalmological emergency department complaining of significant loss of visual acuity and pain in the right eye persisting for 2 weeks. The patient had a history of type II diabetes mellitus, hypertension, status post ACS and PCI, and long-term nicotinism. Examination of the right eye revealed ocular irritation, mixed conjunctival injection, hyphema in the anterior chamber, iris neovascularization, and discrete central retinal fading. Additional examinations were performed, including an angioCT, which showed a long-standing obstruction of the right internal carotid artery, a ballooning thrombus in the lumen of the brachiocephalic trunk, and suspected critical stenosis of the left vertebral artery.\u0000 A neurologist and vascular surgeon were consulted, and treatment was instituted to limit further complications from the underlying disease. The patient remains under close supervision of the vascular surgeon and neurologist.\u0000 \u0000 \u0000 \u0000 OIS is a rare but potentially blinding condition and should be considered in the differential diagnosis of transient visual acuity reduction or vision loss.\u0000","PeriodicalId":20344,"journal":{"name":"Postępy Higieny i Medycyny Doświadczalnej","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140524201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiology of childhood acute leukemias 儿童急性白血病流行病学

Postępy Higieny i Medycyny Doświadczalnej Pub Date : 2024-01-01 DOI: 10.2478/ahem-2023-0023

Marzena Ciesielska, Beata Orzechowska, Andrzej Gamian, Bernarda Kazanowska

{"title":"Epidemiology of childhood acute leukemias","authors":"Marzena Ciesielska, Beata Orzechowska, Andrzej Gamian, Bernarda Kazanowska","doi":"10.2478/ahem-2023-0023","DOIUrl":"https://doi.org/10.2478/ahem-2023-0023","url":null,"abstract":"\u0000 Acute leukemias are the largest group of childhood cancers. According to the latest WHO data 80,491 leukemias were diagnosed in 2020 alone. In the coming years the incidence worldwide will continue at a similar level. The morbidity correlates with biological determinants such age, gender and race. The etiology of leukemia formation is complex and depends on genetic, physiological, environmental and even prior treatment-related factors. Both the incidence and curability are also influenced by age, gender, and race. The peak of incidence of leukemia occurs between the ages of 1–4 years and 9–19. The etiology of leukemia formation is complex and depends on genetic, physiological, environmental and even prior treatment-related factors. Boys suffer from leukemia more often than girls. In 2020 58.2% of diagnoses were for boys. Numerous factors contribute to the development of acute leukemia. In the case of young children, a notable association exists between acute leukemia and infections caused by viruses such as EBV or HHV-6. Furthermore, the risk of leukemia can be elevated by allergies, which involve Th1/Th2 lymphocyte-dependent mechanisms. A familial predisposition to tumorigenesis in children is observed in Li-Fraumeni Syndrome. Also, genetic diseases such as Down syndrome and Fanconi anemia are associated with an increased risk of acute leukemia. Previous exposure to radiation therapy or the use of anti-cancer drugs can also lead to the development of secondary cancers, including leukemia. The analysis of risk factors can be used to support efforts aimed to reduce potentially harmful exposure and to decrease the risk of disease.","PeriodicalId":20344,"journal":{"name":"Postępy Higieny i Medycyny Doświadczalnej","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140523825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0