Ricos Biology最新文献

{"title":"Antibiogram Screening of Bacterial Pathogens Obtained From Respiratory ‎Manifested Patients in Great Cairo ‎","authors":"E. Fouad, A. Maher, M. Salman","doi":"10.33687/ricosbiol.01.01.0013","DOIUrl":"https://doi.org/10.33687/ricosbiol.01.01.0013","url":null,"abstract":"Respiratory tract infections are the most prevalent infections and implemented in hundred thousand deaths among humans globally, especially in the last years. The goal of the current investigation was to determine the prevalence and antibiotic sensitivity pattern of microorganisms isolated from respiratory samples obtained from laboratories in Great Cairo between January to June 2022. A total of 107 samples distributed as fifteen naso-oral, forty three throat and forty nine sputum were collected. Among them, 91 samples (85.04%) exhibited significant microbial growth on culture media and near equal rate in patients with male and female gender (46 and 45 respectively). The most susceptible ages were both under 12 and over 50 years. The microorganism identification and antibiotic susceptibility testing were conducted. Out of 91isolates species, 56 (61.54%) were Gram-negative bacteria, 35 (38.46%) were Gram-positive bacteria. Prime microorganisms isolated were Klebsiella pneumonia 28 (30.77%), Streptococcous pneumonia 26 (28.57%), Staphylococcous aureus 9 (9.9%), Pseudomonas aeruginosa 8 (8.79%), Escherichia coli (E. coli) 8 (8.79%), Citrobacter spp. 7 (7.69%), Proteus vulgaris 4 (4.4%) and one sample positive for non-lactose fermenting (NLF) E. coli (1.1%). In antimicrobial susceptibility assay, the isolates were mostly resistant to many antibiotics; particularly amoxicillin-clavulanic acid, ampicillin, ceftazidime, clindamycin, oxicillin and trimethoprim-sulfamethoxazole. On the other hand the isolates exposed maximum susceptibility to imipenem and piperacillin-tazobactam (100%), as well as cefoperazone-sulbactam (96.66%) and amikacin (85%).In conclusion, the precise identification of causative microorganisms and their susceptibility profiles to antibiotics is pivotal for selecting targeted and effective antibiotic therapy in respiratory tract infections, and to hinder the emergence of multidrug-resistant bacteria. Gram-negative bacteria exhibited the species most commonly obtained. A high rate of drug resistance was observed in this investigation which may be of public health significance.","PeriodicalId":201643,"journal":{"name":"Ricos Biology","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116836161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overview on the Role of Probiotics as Immunomodulator s in Farm Animals","authors":"E. Fouad","doi":"10.33687/ricosbiol.01.01.0018","DOIUrl":"https://doi.org/10.33687/ricosbiol.01.01.0018","url":null,"abstract":"Probiotics are beneficial microorganisms that improve the microbial balance of a host animal in all species. Immunomodulators are substances that keep tuning the immune system, so that probiotics are considered as immunomodulators that can stimulate the immune system of the host. Probiotics have many different bacterial species, Lactobacillus, Bifidobac­terium, Bacillus and Enterococcus. They used to ameliorate certain physiological functions, safeguard of disease and mitigation of risk factors. Immunomodulation is a complex phenomenon that needs careful consideration, understanding of mechanisms of probiotic activities and immune functionality along either systematic or locally in GIT. \u0000Probiotics able to modulate the immune response via regulating the mediators secreted by intestinal immune system cells and T helper cell as well as regulatory cell stimulation. The interactions between probiotics and immune cells (enterocytes) are complex that is not achieved by a single mechanism. Probiotics are not immune specific, but they have been shown different mechanisms like production of mucin, reduction of permeability of GIT, increasing phagocytic capacity and activation of macrophage and natural killer (NK) cell. On the other hand, cytokines and other regulatory substances are increasing as well as antibodies production (IgA, IgM, and IgG). This review has discussed the probiotics immunological mechanisms in the farm animals.","PeriodicalId":201643,"journal":{"name":"Ricos Biology","volume":"19 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132570326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comprehensive Update on Diagnosis of SARS-CoV-2","authors":"Soheir M. Syame, Aya A. Mabrouk, A. Hakim","doi":"10.33687/ricosbiol.01.01.0016","DOIUrl":"https://doi.org/10.33687/ricosbiol.01.01.0016","url":null,"abstract":"An unmatched coronavirus; termed Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has been arisen in the end of 2019 in Wuhan, China resulted in a pandemic COVID-19 disease. In 2021, there were many mutations disseminated all over the world termed variants of concern. One of the critical main challenges is how to diagnose precisely the disease without confusion with another flu and respiratory distress causing viruses. The various clinical, radiological, laboratory, serological and molecular diagnostic approaches were discussed in this article.","PeriodicalId":201643,"journal":{"name":"Ricos Biology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115993797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body versus SARS-CoV-2 Virus Spotlights on Virus Pathogenesis Human Immunity Interactivity","authors":"Shraf S. Hakim","doi":"10.33687/ricosbiol.01.01.0014","DOIUrl":"https://doi.org/10.33687/ricosbiol.01.01.0014","url":null,"abstract":"A novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV- 2) causes COVID-19; a newly emerged global pandemic disease and found to be more infective and more pathogenic than former human respiratory corona viruses due to its higher specific receptor binding affinity. Exposed COVID-19 data clearly recognize that the human immune response to SARS-CoV-2 is the prime factor affecting the course of disease. This article places emphasis on virus pathogenesis, host cell interaction, immunological response for COVID-19 trying to light on the obscured areas of this novel human health menace.","PeriodicalId":201643,"journal":{"name":"Ricos Biology","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133818642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beneficial Implementation of Probiotics in Farm Animals and Poultry Husbandry","authors":"E. Fouad, Magdy A. Kamel, A. Hakim","doi":"10.33687/ricosbiol.01.01.0017","DOIUrl":"https://doi.org/10.33687/ricosbiol.01.01.0017","url":null,"abstract":"Probiotics have become highly realized as additives for livestock because of their beneficial impacts on health and well-being. The current article aims to provide knowledge about the potential probiotic microbial strains referred to their relation to animal health. Lactic acid bacteria are the most regularly used microorganisms as probiotics, \"besides other microbiota including certain fungi\" which can be obtained from human, animal, plant, and environment. Not all microbiota be a good probiotic but there are main selection criteria for any potential probiotic microorganism. Nowadays, probiotics are used on large scale as growth promoters and productivity enhancers in both poultry and farm animals. Finally, the promising probiotic must achieve the safety status for humans or animals and lack of antibiotic resistance genes transfer.","PeriodicalId":201643,"journal":{"name":"Ricos Biology","volume":"341 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122143410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Considerations about Genomic and Proteomic of (SARS-CoV)-2 and Concern Variants","authors":"Soheir M. Syame, A. Hakim","doi":"10.33687/ricosbiol.01.01.0015","DOIUrl":"https://doi.org/10.33687/ricosbiol.01.01.0015","url":null,"abstract":"A novel coronavirus that related to previous SARS-CoV and Middle East respiratory syndrome coronaviruses, has been emerged in the end of 2019 in China and rapidly human to human transmitted causing what is termed pandemic COVID-19 illness. The causative agent was termed severe acute respiratory syndrome coronavirus (SARS-CoV)-2, and suggested to be of bat corona virus’s origin. Later on, other virus variants were emerged and become as great concern. The investigated genomic and proteomic structures of the novel virus were rather mentioned in this article.","PeriodicalId":201643,"journal":{"name":"Ricos Biology","volume":"229 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122052631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}