Cardiovascular Diseases and Diagnosis最新文献

{"title":"Effects of Renal Transplantation on Cardiac Morphology and Function Luis Vernaza Hospital, Guayaquil, Ecuador: Kidney Transplant and Morphology and Cardiac Function","authors":"Byron Zúñiga Pineda, J. Lara-Terán, Paola Alprecht-Quiroz, Silvia V. Cáceres-Vinueza, Y. Duarte","doi":"10.31487/j.cdd.2020.01.04","DOIUrl":"https://doi.org/10.31487/j.cdd.2020.01.04","url":null,"abstract":"Introduction: Structural heart disease is a frequent complication of advanced chronic kidney disease and\u0000the leading cause of death in patients with renal replacement therapy, mainly in those on dialysis. There is\u0000sufficient evidence to demonstrate a regression of left ventricular hypertrophy and improvement of\u0000ventricular function after a successful renal transplant. The objective of this study is to describe the\u0000experience regarding the effects of renal transplantation on cardiac remodeling and function and thus\u0000corroborate with local data the benefits of renal transplantation on the left ventricular mass index (LVMI\u0000grs), Left Ventricle Ejection Fraction (LVEF %), Left Atrium Diameter (LAD mm), Left Ventricle Diastolic\u0000Diameter (LVDD mm), Left Ventricle Systolic Diameter (LVSD mm), Posterior Wall (PW mm) and\u0000Interventricular Septum (IVS mm).\u0000Materials and Methods: This is a quantitative, observational, descriptive and retrospective study. A\u0000database was constructed whose information was tabulated and subsequently analysed by the statistical\u0000program SPSS 13 to perform the statistical analysis. The results of the nominal variables were expressed in\u0000percentages and of the numerical variables in average ± standard deviation (SD) and confidence interval.\u0000The study included all adults over18 years with a diagnosis of chronic renal failure who underwent renal\u0000transplantation at Luis Vernaza Hospital between January 2009 to December 2016 and who had pre and\u0000post-transplant transthoracic echocardiography.\u0000Results: Of the 132 adults undergoing renal transplantation, 74 patients who met the inclusion criteria were\u0000identified, their average age was 35.2 years DS (+/- 11.7 years), forty-eight patients (64%) were male. All\u0000patients were dependent on dialysis, whose average time was 5 years and 88% of the population underwent\u0000intermittent hemodialysis weekly. The pre-transplant and post-transplant echocardiographic measurements\u0000were: LVEF (%) 60.89 ± 1,175 vs. 66.81 ± 0.685 (<0.0001); LVMI (grs) 242.54 ± 11.92 vs. 184.62 ± 7,591\u0000(<0.0001); LAD (mm) 35.9 ± 0.772 vs. 34.8 ± 0.602 (0.215); LVDD (mm) 47.97 ± 0.756 vs. 44.98 ± 0.927\u0000(0.003); LVDS (mm) 29.85 ± 0.897 vs. 26.68 ± 0.681 (0.004); PW (mm) 11.86 ± 0.270 vs. 10.92 ± 0.208\u0000(0.002); IVS (mm) 12.12 ± 0.348 vs. 10.95 ± 0.253 (0.002) respectively.\u0000Conclusion: In this study, was observed a favorable overall impact of renal transplantation on the structure\u0000and function of the heart, with a significant reduction in LVH and LVMI and systolic and diastolic function\u0000of the left ventricle, thus reducing the risk of associated death to cardiovascular events.","PeriodicalId":196275,"journal":{"name":"Cardiovascular Diseases and Diagnosis","volume":"196 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115486879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}