Gene Expression and Phenotypic Traits最新文献

Introductory Chapter: Gene Expression and Phenotypic Traits 导论:基因表达和表型性状

Gene Expression and Phenotypic Traits Pub Date : 2020-04-01 DOI: 10.5772/intechopen.89863

Yuan Chen

引用次数: 0

Transcriptional and Epigenetic Regulation of Krüppel-Like Transcription Factors kr<s:1> ppel样转录因子的转录和表观遗传调控

Gene Expression and Phenotypic Traits Pub Date : 2020-03-05 DOI: 10.5772/intechopen.91652

Morgan D. Salmon

引用次数: 2

Specific Features of Sex Determination in Birds on the Example ofGallus gallusdomesticus 鸟类性别决定的特征——以家鸡为例

Gene Expression and Phenotypic Traits Pub Date : 2020-02-12 DOI: 10.5772/intechopen.91178

A. Smirnov, A. V. Trukhina

引用次数: 1

Environmental Factors Affecting the Expression of Bilateral-Symmetrical Traits in Plants 影响植物双侧对称性状表达的环境因子

Gene Expression and Phenotypic Traits Pub Date : 2019-12-13 DOI: 10.5772/intechopen.89460

S. Baranov, I. Vinokurov, L. Fedorova

{"title":"Environmental Factors Affecting the Expression of Bilateral-Symmetrical Traits in Plants","authors":"S. Baranov, I. Vinokurov, L. Fedorova","doi":"10.5772/intechopen.89460","DOIUrl":"https://doi.org/10.5772/intechopen.89460","url":null,"abstract":"In recent years, there has been a growing interest in the problem of asymmetry of bilateral traits in plants. Three types of bilateral asymmetry are found in the leaf blade, of interest to ecologists and evolutionists. A brief review of the methods used in testing bilateral asymmetry and developmental stability discusses their role in the development of homeostasis and ontogenesis. Intra- and interspecific differences are considered on the example of woody plants under the influence of factors influencing the expression of bilaterally symmetry. The influence of stress on the manifestation of asymmetric traits is considered. Apparently, the climate and topography of the area play a more important role, determining the plastic and fluctuating variability. The relationship of plasticity, evolutionary canalization, and development stability is considered on the example of woody and cultivated plants. Plasticity and fluctuation variability are in a relationship coordinated by climatic conditions, primarily lighting and temperature. This, in turn, determines the mechanisms of gene regulatory networks. Thus, phenogenetics, which studies the patterns and mechanisms of gene expression and ontogenesis, is based on the data from field botanical studies of plant shape and asymmetry. Epigenetic and population studies of phenotypic variations play a role in standardizing and finding suitable plant species and varieties.","PeriodicalId":195225,"journal":{"name":"Gene Expression and Phenotypic Traits","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122773878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Circular RNAs and Its Biological Functions in Health and Disease 环状rna及其在健康和疾病中的生物学功能

Gene Expression and Phenotypic Traits Pub Date : 2019-10-07 DOI: 10.5772/intechopen.88764

A. Sağlam, E. Alp, H. Onen

{"title":"Circular RNAs and Its Biological Functions in Health and Disease","authors":"A. Sağlam, E. Alp, H. Onen","doi":"10.5772/intechopen.88764","DOIUrl":"https://doi.org/10.5772/intechopen.88764","url":null,"abstract":"Circular RNAs (circRNAs) belong to the family of long noncoding RNAs (lncRNA) that, unlike linear RNAs, are characterized by a covalently closed circular RNA structure lacking 5 0 cap and 3 0 poly-adenylated tails. circRNAs have a role in epigenetic regulation of downstream targets. circRNAs play a crucial role in regulating gene and protein expressions by acting as a microRNA (miRNA) sponge and RNA binding protein (RBP) sponge and interact with proteins to affect cell behav-ior. circRNA expression profiles differ between physiological and pathological states. Moreover, the expression patterns of circRNAs exhibit differences in a tissue-specific manner. Although investigations on circRNAs have been exploding nowadays, yet only a limited number of circRNAs are identified. Furthermore, further researches are needed to shed light on their functions and targets. Therefore, circRNAs are becoming vital as potential biomarkers that may be used for the diagnosis and treatment of diseases. In this chapter, we review the current advancement of cirRNAs with regard to their biogenesis, biological functions, gene regulatory mechanisms, and implications in human diseases and summarize the recent studies on circRNAs as potential diagnostic and prognostic biomarkers based on existing knowledge.","PeriodicalId":195225,"journal":{"name":"Gene Expression and Phenotypic Traits","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116311636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Gene Expression Profile of HDF in SMG Partially Overlaps with That in the NASA Twins Study SMG中HDF基因表达谱与NASA双胞胎研究中部分重叠

Gene Expression and Phenotypic Traits Pub Date : 2019-09-26 DOI: 10.5772/intechopen.88957

J. Q. Clement

引用次数: 0

Instability of Sex-Determining Systems in Frogs 青蛙性别决定系统的不稳定性

Gene Expression and Phenotypic Traits Pub Date : 2019-09-09 DOI: 10.5772/intechopen.89050

Michihiko Ito

引用次数: 0

Sellafield, Seascale, and Scandinavia: A Legacy of Radioactive Contamination with Future Implications for Gene Evolution in Affected Ecosystems 塞拉菲尔德、海鳞和斯堪的纳维亚:受影响生态系统中放射性污染的遗产及其对基因进化的未来影响

Gene Expression and Phenotypic Traits Pub Date : 2019-07-30 DOI: 10.5772/INTECHOPEN.88505

C. Siddoo-Atwal

{"title":"Sellafield, Seascale, and Scandinavia: A Legacy of Radioactive Contamination with Future Implications for Gene Evolution in Affected Ecosystems","authors":"C. Siddoo-Atwal","doi":"10.5772/INTECHOPEN.88505","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.88505","url":null,"abstract":"Radioactive waste from nuclear installations and nuclear reprocessing plants, nuclear accidents, and radioactive fallout from nuclear weapons testing constitute a serious problem facing future generations. Marine algae and phytoplanktons accumu-late radionuclides from their surroundings and are used as bioindicators of radioactive pollution in the environment. In Northern Europe, the affected marine systems include the Irish Sea, the Baltic Sea, and the North Sea. The main sources of this radioactive contamination are global fallout from nuclear weapons tests, river transport from Siberia, and marine transport of discharges from Sellafield and Chernobyl. An increased leukemia incidence has been observed in young children at Seascale near Sellafield, and an elevated incidence of leukemia has been recorded among young people (0–24 years) in the French canton of Beaumont-Hague close to the Cap de la Hague nuclear reprocessing facility. In Scandinavia, scientists suspect that people in parts of Sweden are still dying from cancer caused by radiation from the Chernobyl accident. Moreover, the Baltic Sea is contaminated with man-made plutonium radionuclides from nuclear reprocessing. However, some experts are able to dismiss the above relationships due to important uncertainties over the estimation of radiation doses from environmental discharges based on a mutational theory of carcinogenesis. Consequently, it appears to be of paramount importance to reevaluate the current methods for cancer risk assessment in the case of radiation exposure within the context of an apoptotic model of carcinogenesis that could explain such a discrepancy. According to this new model, subtle differences in gene expression in response to a carcinogen can initiate cell death or apoptosis and act as a trigger for carcinogenesis. Simultaneously, future implications for human gene evolution are unavoidable.","PeriodicalId":195225,"journal":{"name":"Gene Expression and Phenotypic Traits","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128544924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Sex Determination in Vertebrates (Nonmammals) 脊椎动物(非哺乳动物)性别决定的比较

Gene Expression and Phenotypic Traits Pub Date : 2019-02-05 DOI: 10.5772/INTECHOPEN.83831

Aleksandr F. Smirnov, Antonina V. Trukhina

引用次数: 2