Sarcoidosis and Granulomatosis - Diagnosis and Management最新文献

Cardiac Sarcoidosis 心脏结节病

Sarcoidosis and Granulomatosis - Diagnosis and Management Pub Date : 2020-07-29 DOI: 10.5772/intechopen.85310

Jhan Carlos Altamar Castillo, Miguel Jose Tejeda Camargo

引用次数: 0

Pathology of Sarcoidosis and Differential Diagnostics of other Granulomatous Diseases 肉芽肿病的病理及其他肉芽肿性疾病的鉴别诊断

Sarcoidosis and Granulomatosis - Diagnosis and Management Pub Date : 2020-07-29 DOI: 10.5772/intechopen.90693

M. Samsonova, A. Chernyaev

{"title":"Pathology of Sarcoidosis and Differential Diagnostics of other Granulomatous Diseases","authors":"M. Samsonova, A. Chernyaev","doi":"10.5772/intechopen.90693","DOIUrl":"https://doi.org/10.5772/intechopen.90693","url":null,"abstract":"Granulomatous diseases are the heterogeneous group of the conditions of different etiologies with a variety of clinic syndromes and morphological features and nonuniform sensitivity to therapy, and the existence of granulomas as general dominate histological expression. Granuloma is indicative of chronic inflammation involving cells of the macrophage system and other inflammatory cells. After the antigen exposure, the activation of T-lymphocytes, macrophages, and epithelioid histiocytes leads to granuloma formation. Granuloma also contains the extracellular matrix produced by fibroblasts, which provide the boundary and isolation of antigen. Their etiology may classify granulomatous diseases as infectious and noninfectious. However, recent studies demonstrate that pathogenic microorganisms may cause the granuloma formation in diseases previously considered as noninfectious. In some cases, differentiation between infectious and noninfectious processes may be problematic. This chapter aims to highlight the multiformity of granulomatous diseases, characterize the pathologic features of different infectious and noninfectious granulomatosis, and delineate the diagnostic approach.","PeriodicalId":185700,"journal":{"name":"Sarcoidosis and Granulomatosis - Diagnosis and Management","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121106496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Particularities of Hepatic Sarcoidosis 肝结节病的特点

Sarcoidosis and Granulomatosis - Diagnosis and Management Pub Date : 2020-07-29 DOI: 10.5772/intechopen.90694

L. Iliescu, L. Toma

引用次数: 0

Granulomatous Diseases Mimicking Sarcoidosis 类似结节病的肉芽肿性疾病

Sarcoidosis and Granulomatosis - Diagnosis and Management Pub Date : 2020-05-16 DOI: 10.5772/intechopen.92233

Ángel Robles-Marhuenda

{"title":"Granulomatous Diseases Mimicking Sarcoidosis","authors":"Ángel Robles-Marhuenda","doi":"10.5772/intechopen.92233","DOIUrl":"https://doi.org/10.5772/intechopen.92233","url":null,"abstract":"Granulomatous diseases are not infrequent in daily clinical practice. Granulomas are the expression of a sufficiently (partial) functioning immune system. Many diseases, with different etiologies (infection, autoimmunity, inflammatory, foreign bodies, malignancy, metabolites, chemicals, etc.) can cause granulomatous manifestations. The differential diagnostic process of a granulomatous disease should always be made in an interdisciplinary cooperation. Diagnostic procedures should be oriented to the clinical symptoms suggestive microbiological studies, and radiography but the diagnosis of a granulomatous disease should always be confirmed by histopathology when possible, sampling for histology or cytology. From a pathogenic point of view, they are divided into noninfectious and infectious granulomas. In the case of proven granulomatous inflammation, an infectious etiology should first be excluded (including mycobacteria, parasites, and fungi). From a clinical point of view, it is useful to separate granulomatosis into localized and disseminated forms, although this distinction can be sometimes artificial. Three types of localized granulomatous lesions can be distinguished: infectious granulomas, palisaded granulomas (granuloma annulare, necrobiosis lipoidica, and rheumatoid nodules), and foreign body granulomas. Disseminated granulomas can be divided into infectious, in particular tuberculosis, and noninfectious forms (autoimmune, neoplasia, etc.).","PeriodicalId":185700,"journal":{"name":"Sarcoidosis and Granulomatosis - Diagnosis and Management","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122570777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Granulomatous Interstitial Nephritis in Children Resulting from Wegener’s Granulomatosis, Crohn’s Disease, or Sarcoidosis 由韦格纳肉芽肿病、克罗恩病或结节病引起的儿童肉芽肿性间质性肾炎

Sarcoidosis and Granulomatosis - Diagnosis and Management Pub Date : 2019-03-19 DOI: 10.5772/INTECHOPEN.84491

G. Makovetskaya, L. Mazur, E. Balashova

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Introductory Chapter: Orofacial Sarcoidosis and Noncaseating Granulomatosis 导论章:口面结节病和非干酪化肉芽肿病

Sarcoidosis and Granulomatosis - Diagnosis and Management Pub Date : 2018-12-31 DOI: 10.5772/INTECHOPEN.83364

Sharareh Kamfar, T. Azizi, M. Motamedi

引用次数: 0