TRC Journal of Medicine最新文献

The Significance of Ventilator-Associated Pneumonia in SARS-CoV-2 Patients: A Systematic Review 呼吸机相关性肺炎在SARS-CoV-2患者中的意义:系统综述

TRC Journal of Medicine Pub Date : 2022-02-28 DOI: 10.55280/trcjm.2022.1.1.0005

L. Szarpak, J. Smereka, A. Gąsecka, G. Borkowska, M. Pruc, B. Daniel

{"title":"The Significance of Ventilator-Associated Pneumonia in SARS-CoV-2 Patients: A Systematic Review","authors":"L. Szarpak, J. Smereka, A. Gąsecka, G. Borkowska, M. Pruc, B. Daniel","doi":"10.55280/trcjm.2022.1.1.0005","DOIUrl":"https://doi.org/10.55280/trcjm.2022.1.1.0005","url":null,"abstract":"Introduction: We performed a systematic review to compare the prevalence and mortality burden of ventilator-associated pneumonia (VAP) in SARS-CoV-2 patients. Material and methods: We conduct this systematic review and meta-analysis according to Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) statement. We searched PubMed, Scopus, Web of Science, Embase, and Cochrane from the database’s inception to February 10, 2021. Results: Five studies were identified. VAP occurred in 45.2% in the COVID-19 group compared to 26.0% for the non-COVID-19 group (OR = 3.17; 95% CI [1.94, 5.18]; p < 0.001; I2 = 67%). Three studies showed VAP recurrence to be 41.6% in the COVID-19 group and 20.2% in the non-COVID-19 group (OR = 3.12; 95% CI [1.87, 5.22]; p < 0.001; I2 = 0%). The mortality rate in COVID-19 vs. non-COVID-19 varies, amounting to 32.1% and 26.3%, respectively (OR = 1.33; 95% CI [1.07, 1.66]; p = 0.010; I2 = 49%). Conclusions: The findings from this case series reveal that the presence of ventilator-associated pneumonia in SARS-CoV-2 patients is a source of significant mortality. This study strengthens the importance of non-invasive mechanical ventilation strategies and also highlights the need for careful infection control surveillance in invasive mechanical ventilation. Due to the high rates of VAP and associated increased mortality, uprating antibiotic/antifungal therapy selection is also paramount in caring for SARS-CoV-2 cases admitted to the ICU.","PeriodicalId":184958,"journal":{"name":"TRC Journal of Medicine","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122828121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of the COVID-19 pandemic on the anxiety levels of patients admitted to emergency departments 新冠肺炎大流行对急诊科住院患者焦虑水平的影响

TRC Journal of Medicine Pub Date : 2022-02-28 DOI: 10.55280/trcjm.2022.1.1.0001

Gorkem Alper Solakoglu, C. Nuhoglu, S. Nuhoğlu, K. Aciksari

引用次数: 0

Healthcare resilience to extreme events: a hospital staff perspective 医疗保健对极端事件的弹性:医院工作人员的观点

TRC Journal of Medicine Pub Date : 2022-02-28 DOI: 10.55280/trcjm.2022.1.1.0004

Afsar Ali, N. Achour

{"title":"Healthcare resilience to extreme events: a hospital staff perspective","authors":"Afsar Ali, N. Achour","doi":"10.55280/trcjm.2022.1.1.0004","DOIUrl":"https://doi.org/10.55280/trcjm.2022.1.1.0004","url":null,"abstract":"The coronavirus (COVID-19) pandemic demonstrated how vulnerable and unprepared most health-care sectors are to major disasters. Several studies have been published reporting factors that affect staff attendance during extreme events. However, these factors are limited and do not provide a full picture of why staff do or do not attend workplaces during major emergencies nor the impact of staff absences on healthcare service delivery. This study presents the factors influencing staff attendance during an extreme event and the impact staff attendance has on the continuity of healthcare services in one of the several independent British Isles hospitals. This study highlights that staff attendance depends on many contributors such as workload, stress, motivation, proximity of work to home, transportation networks, and dependents. The absence of any staff member, despite their role, level, or background, will have an impact on the functionality of a hospital. The study concludes that staff absence severely impedes the continuity of healthcare service, impacting services that provide ventilators and other essential services required during extreme events such as the COVID-19 pandemic and extreme weather events.","PeriodicalId":184958,"journal":{"name":"TRC Journal of Medicine","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132384337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Lymphopenia a sign of mortality in coronavirus disease 2019 patients? 淋巴细胞减少是2019冠状病毒病患者死亡的标志吗?

TRC Journal of Medicine Pub Date : 2022-02-28 DOI: 10.55280/trcjm.2022.1.1.0006

Leyla Öztürk Sönmez, Neslişah Akdağ, Gülru Ekinci, A. Sahin, Kerim Oruç, Simge Güzelsoy, Elif Kızılkaya, Çağdaş Yıldırım, T. Evrin

{"title":"Is Lymphopenia a sign of mortality in coronavirus disease 2019 patients?","authors":"Leyla Öztürk Sönmez, Neslişah Akdağ, Gülru Ekinci, A. Sahin, Kerim Oruç, Simge Güzelsoy, Elif Kızılkaya, Çağdaş Yıldırım, T. Evrin","doi":"10.55280/trcjm.2022.1.1.0006","DOIUrl":"https://doi.org/10.55280/trcjm.2022.1.1.0006","url":null,"abstract":"Aim: A novel type of coronavirus was detected after the first case of an atypical pneumonia in Wuhan, China in December 2019; the World Health Organization (WHO) named the virus SARS-CoV-2 in February 2020 and the disease it caused COVID-19. This classification has allowed clinicians to plan its treatment process to progress faster. We aim to compare laboratory parameters in COVID-19. Material and Methods: The patient population of the study has been formed by retrospectively examining the files of patients who had been admitted with COVID-19 complaints to an emergency department at a faculty of medicine between April 27 and December 18, 2020. Patients were divided into two groups: the surviving group and the mortal group. Results: In the ROC analysis, we evaluate the effect of lymphocyte on mortality, the cut-off value for lymphocyte was found as 1.3 (sensitivity = 58.14%; specificity = 78.92%). The sensitivity and specificity of this cutoff value are at good levels (AUC = 0.712; p < 0.05). Conclusion: We believe that lymphocyte levels in particular may be used to distinguish severe COVID-19 cases from mild to moderate cases in the days after hospital admissions.","PeriodicalId":184958,"journal":{"name":"TRC Journal of Medicine","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123983843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Convalescent plasma operations during the COVID-19 pandemic: The Turkish Red Crescent’s experience 2019冠状病毒病大流行期间恢复期血浆手术:土耳其红新月会的经验

TRC Journal of Medicine Pub Date : 2022-02-28 DOI: 10.55280/trcjm.2022.1.1.0007

Eda Çetiner, Şeyda Canpolat, Sıdıka Selin Çöplen, Z. Kaya, Begül Karadere, Metin Kalender, Nurettin Hafizoglu, Kerem Kınık, F. Yilmaz

{"title":"Convalescent plasma operations during the COVID-19 pandemic: The Turkish Red Crescent’s experience","authors":"Eda Çetiner, Şeyda Canpolat, Sıdıka Selin Çöplen, Z. Kaya, Begül Karadere, Metin Kalender, Nurettin Hafizoglu, Kerem Kınık, F. Yilmaz","doi":"10.55280/trcjm.2022.1.1.0007","DOIUrl":"https://doi.org/10.55280/trcjm.2022.1.1.0007","url":null,"abstract":"After COVID-19 was first observed in Wuhan at the end of 2019, it spread all over the world and became a pandemic which has yet to end. The United States Food and Drug Administration (FDA) suggested that convalescent plasma obtained from individuals who’ve recovered from COVID-19 might be helpful in treating COVID-19 infections, and this treatment has started to be applied in various countries. Convalescent plasma started to be used in Turkey to treat COVID-19 as per a decision of the Ministry of Health. The Turkish Red Crescent has been placed in charge of the convalescent plasma supply. In this scope, objectives for recruiting convalescent plasma donors have been set in motion. The supply of convalescent plasma required for COVID -19 treatment has been conducted in three main stages: managing the course of operations, determining donor selection criteria, and recruiting donors. For the course of operations, convalescent plasma donation centers have been founded, and a national reference guide has been prepared about convalescent plasma donations in addition to documents for providing standard practices in line with this guide. Convalescent plasma donor selection criteria have been defined, followed by convalescent plasma donor recruitment strategies. This study summarizes the Turkish Red Crescent’s experiences and the strategies used to encourage individuals to donate convalescent plasma.","PeriodicalId":184958,"journal":{"name":"TRC Journal of Medicine","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134100839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing Vie Scope® and Macintosh Laryngoscopes in Suspected/Confirmed COVID-19 Cardiac Arrest Patients Being Intubated by Paramedics: A Prospective Randomized Crossover Simulation Trial 比较Vie Scope®和Macintosh喉镜在医护人员插管的疑似/确诊COVID-19心脏骤停患者中的应用:一项前瞻性随机交叉模拟试验

TRC Journal of Medicine Pub Date : 2022-02-28 DOI: 10.55280/trcjm.2022.1.1.0002

P. Wieczorek, Maciej Maslanka, M. Malysz, W. Wieczorek, M. Zieliński, Marta Grycan, L. Konge, L. Szarpak

{"title":"Comparing Vie Scope® and Macintosh Laryngoscopes in Suspected/Confirmed COVID-19 Cardiac Arrest Patients Being Intubated by Paramedics: A Prospective Randomized Crossover Simulation Trial","authors":"P. Wieczorek, Maciej Maslanka, M. Malysz, W. Wieczorek, M. Zieliński, Marta Grycan, L. Konge, L. Szarpak","doi":"10.55280/trcjm.2022.1.1.0002","DOIUrl":"https://doi.org/10.55280/trcjm.2022.1.1.0002","url":null,"abstract":"Aim: This study was designed with the aim of evaluating Vie Scope®’s role in placing an endotracheal tube (ETT) by paramedics wearing full personal protective equipment who are experienced in direct laryngoscopy but inexperienced in using the Vie Scope® for intubation. Material and Methods: Twenty-seven paramedics participated in this prospective, randomized, single-blinded crossover simulation trial using manikins. Participants performed endotracheal intubation on simulated adult cardiac arrest patients with suspected/confirmed COVID-19. During all procedure’s, paramedics wore Level C personal protective equipment (PPE). Primary endpoint was time to intubation (TTI). Results: Time to intubation using the Vie Scope was 43.5±12 seconds, statistically significantly faster than the Macintosh laryngoscope at 57.5±15.6 seconds (MD = -14.00; 95% CI [-21.42, -6.58]; p < 0.001). First pass success rate using the Vie Scope® and Macintosh laryngoscope was 88.9% and 63.0%, respectively (OR = 4.71; 95% CI [1.12, 19.70]; p = 0.03). The overall intubation success rate was 100% for each group. Conclusions: With paramedics wearing full PPE, the Vie Scope laryngoscope provided faster endotracheal intubation and a better first pass success rate than the Macintosh laryngoscope. Further studies involving clinical trials are necessary to confirm these results.","PeriodicalId":184958,"journal":{"name":"TRC Journal of Medicine","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131861008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0