Neurodevelopment and Neurodevelopmental Disease [Working Title]最新文献

Autism: A Neurodevelopmental Disorder and a Stratum for Comorbidities 自闭症:一种神经发育障碍和共病的一个阶层

Neurodevelopment and Neurodevelopmental Disease [Working Title] Pub Date : 2019-05-08 DOI: 10.5772/INTECHOPEN.82496

M. Saleh, A. Adel

{"title":"Autism: A Neurodevelopmental Disorder and a Stratum for Comorbidities","authors":"M. Saleh, A. Adel","doi":"10.5772/INTECHOPEN.82496","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82496","url":null,"abstract":"Autism is a neurodevelopmental disorder which is more common in males than females. It is characterized by social communication disorders and restricted repetitive behaviors. There is wide heterogeneity in its etiology, clinical presenta-tions, management and consequently prognosis. Although the etiology of autism remains unclear, the most currently proven theory is that it is a complex neurodevelopmental disorder that displays “brain network abnormalities”. fMRI studies have shown decreased brain connectivity or functional synchronization between frontal and more posterior cortical regions. Dynamic brain activity through high resolution electroencephalograghy (EEG) has revealed local overconnectivity and long-range underconnectivity. This disrupted connectivity pattern would involve connectivity between hemispheres (corpus callosum), together with axonal and synaptic connectivity within each hemisphere. Inconsistent morphometric changes involving both gray and white matter structure also exist. Clinically, autism is associated with multiple comorbidities (somatic, neurologic and psychiatric); some of which are attention deficit hyperactivity disorder, dyspraxia, and sensory processing disorders.","PeriodicalId":176822,"journal":{"name":"Neurodevelopment and Neurodevelopmental Disease [Working Title]","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115133678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systems Biology Perspectives for Studying Neurodevelopmental Events 研究神经发育事件的系统生物学观点

Neurodevelopment and Neurodevelopmental Disease [Working Title] Pub Date : 2019-04-26 DOI: 10.5772/INTECHOPEN.85072

Elodie Mathieux, M. Mendoza-Parra

引用次数: 0

The Role of the DNA Damage Response in Ataxia-Telangiectasia Syndrome DNA损伤反应在共济失调-毛细血管扩张综合征中的作用

Neurodevelopment and Neurodevelopmental Disease [Working Title] Pub Date : 2019-03-28 DOI: 10.5772/INTECHOPEN.84902

Albert Ribes-Zamora

引用次数: 0

The Neurobiological Development of Reading Fluency 阅读流畅性的神经生物学发展

Neurodevelopment and Neurodevelopmental Disease [Working Title] Pub Date : 2019-02-08 DOI: 10.5772/INTECHOPEN.82806

Bobbie Jean Koen

{"title":"The Neurobiological Development of Reading Fluency","authors":"Bobbie Jean Koen","doi":"10.5772/INTECHOPEN.82806","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.82806","url":null,"abstract":"This chapter offers an extensive review of current and foundational research literature on the neurodevelopment of dyslexia and reading fluency worldwide. The impact of different languages and their orthographies on the acquisition of phonological analysis and orthographical features by beginning readers is explored. Contributions from the Psycholinguistic Grain Size Theory and new assessments, i.e. rapid automatized naming, have focused and advanced the understanding of slow phonological and visual processing skills. Recently, the development of new definitions of fluency has led to a proposed continuum of automatized decoding and processing skills required for students of English. Computer technology has enhanced the use of visual hemisphere-specific stimulation to affect the neurodevelopment of efficient word retrieval pathways and to increase reading speed. Processes for subtyping students based on reading behaviors and then stimulating a particular hemisphere of the brain with the fast presentation of words and phrases have been found to change levels of activation in key brain locations and increase the fluent processing of connected text. Newer technologies such as diffusion tensor imaging, while somewhat suspect, may provide the evidence that ultimately will document the changes in communication between regions of interest regulating the automaticity of brain functions in reading.","PeriodicalId":176822,"journal":{"name":"Neurodevelopment and Neurodevelopmental Disease [Working Title]","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123519874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

INA Early Intervention for Babies at Risk 对高危婴儿的早期干预

Neurodevelopment and Neurodevelopmental Disease [Working Title] Pub Date : 2019-01-24 DOI: 10.5772/INTECHOPEN.83610

Hagit Friedman, Marina Soloveichick, A. Kushnir, Chava Kasher, C. Barmatz, O. Bar-Yosef

{"title":"INA Early Intervention for Babies at Risk","authors":"Hagit Friedman, Marina Soloveichick, A. Kushnir, Chava Kasher, C. Barmatz, O. Bar-Yosef","doi":"10.5772/INTECHOPEN.83610","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.83610","url":null,"abstract":"Brain and nervous system development are experience dependent. Indeed, the sequence of development is laid out genetically, but early environmental events are major contributors to the system ’ s development and optimal functioning. Various fetal injuries and birth trauma make babies vulnerable to developmental problems: cerebral palsy, seizures, abnormal muscle tone, delayed developmental milestones, sensory integration, and more. Our goal in the study presented here was to improve the neurodevelopmental track of babies at risk using Infant Neural Aquatic. Parent and baby dyads who met initial criteria were recruited for a 5 – 6 months intervention period through an open invitation, followed by a conversation and signing informed consent. In the beginning and end of intervention period, participants completed questionnaires, and developmental features of the babies were assessed using analysis of neuro-motor and vocal characteristics. Significant neurodevelopmental delta between values at the end and beginning of intervention period, comparing intervention and control, is described, and the strength of INA specific intervention tool is analyzed.","PeriodicalId":176822,"journal":{"name":"Neurodevelopment and Neurodevelopmental Disease [Working Title]","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129521005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1