Sarcoidosis - New Perspectives [Working Title]最新文献

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Radiation Patterns of Modern Sarcoidosis (Alphabet) 现代结节病的放射模式(字母)

Sarcoidosis - New Perspectives [Working Title] Pub Date : 2021-09-01 DOI: 10.5772/intechopen.99822

A. Speranskaia

引用次数: 0

Skeletal Sarcoidosis 骨结节病

Sarcoidosis - New Perspectives [Working Title] Pub Date : 2021-08-24 DOI: 10.5772/intechopen.99811

Henco Nel, Eli Gabbay

{"title":"Skeletal Sarcoidosis","authors":"Henco Nel, Eli Gabbay","doi":"10.5772/intechopen.99811","DOIUrl":"https://doi.org/10.5772/intechopen.99811","url":null,"abstract":"Osseous sarcoidosis is an uncommon manifestation, reported in 3–13% of patients with sarcoidosis. Although older literature suggested that hands and feet are most commonly affected, axial bone involvement may be more common than previously reported, since earlier studies relied mostly on plain X-rays, which may be less sensitive for axial bone lesions. Newer imaging modalities such as MRI and PET/CT scanning have demonstrated a larger incidence of vertebral involvement. Bone lesions are commonly asymptomatic and patients who have bone involvement may have higher incidences of multi-organ involvement. Osseous sarcoidosis appears to be mainly osteolytic in nature, but the radiographic appearance may be indistinguishable from other osteolytic lesions and therefore a biopsy is usually required to confirm the diagnosis. The histological findings of sarcoidosis in the bone are the same as in other tissues of the body. No general consensus exists for the treatment of bone sarcoidosis but corticosteroids are the most commonly prescribed first-line drugs. Methotrexate is the most widely studied steroid-sparing agent for sarcoidosis and it has been reported useful for a variety of organ symptoms, but especially where there is bone involvement.","PeriodicalId":171861,"journal":{"name":"Sarcoidosis - New Perspectives [Working Title]","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132430875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0