Open Journal of Biomedical Research最新文献

{"title":"The relationship between COVID-19 and Helicobacter pylori infections in Zawia, Libya, and their effect on certain blood","authors":"F. Shawesh, E. Lagha, Khadija Alkadea, Abdurraouf Zaet","doi":"10.26629/ojbr.2022.02","DOIUrl":"https://doi.org/10.26629/ojbr.2022.02","url":null,"abstract":"Purpose: Pathogens linked to the most prevalent bacterial and viral infections worldwide are COVID-19 and Helicobacter pylori (H. pylori). The co-infection of COVID-19 and pathogenic microorganisms posed a serious health risk. Several hematological parameters, including platelets, white blood cell total count, lymphocytes, neutrophils, (along with neutrophil-lymphocyte and platelet-lymphocyte ratios), and red blood cells, have also been linked to the presence and severity of COVID-19 infection. This study aims to evaluate the association between COVID-19 Infection and H. Pylori infection and their effects on some blood cell counts. Materials and Methods: One thousand three hundred twenty (1320) COVID-19- infected patients and their blood parameters were examined by ELISA then all data statistics were analyzed. Results: The percentage of H. pylori infection in COVID-19 patients was significantly high in females compared to males (56.30% and 43.70% respectively) (P=0.05) Moreover, there was a significant increase in WBCs (P=0.01), Neutrophil (P=0.004) and platelet counts (P=0.002) count with COVID-19 and H. pylori compared to the healthy group. However, there was a significant decrease in counts of lymphocytes (P=0.01), and RBC counts (P=0.03) between all the comparative groups. Conclusion: There was a significant correlation between H. pylori infection and COVID-19 patients. Also, there was a significant difference (x2 = 2.47, p = 0.03) between all groups according to blood parameters. (Open J Bio Med Res 2022;1:2-6) Keywords COVID-19, Helicobacter pylori, co-infection, hematological parameters.","PeriodicalId":170585,"journal":{"name":"Open Journal of Biomedical Research","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132729127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic characteristics and clinicopathological features of lymphoma (HL and NHL) in Libya","authors":"Jbireal M Jbireal, A. Kharbash, F. Abdalla, Soror Owhida, Nadia Kshot, Ruwayda Abuihbayl, Kholoud Abdulmawlay, S. Abobaker","doi":"10.26629/ojbr.2022.06","DOIUrl":"https://doi.org/10.26629/ojbr.2022.06","url":null,"abstract":"Purpose: To establish the prevalence of lymphoma in Libya and to describe the demographic characteristics of patients based on the official records of the national oncology institute and to mention some of the clinicopathological characteristics to be compared with other results that have been recently published internationally. Materials and Methods: Between 2013 and 2015, 25 lymphoma patients, ranging in age from 15 to 90 (mean age: 43), registered at the National Oncology Institute in Sabratha, were examined for the incidence rate of lymphoma and the identification of epidemiological and clinicopathological aspects. The tumor was divided into stages 1, 2, 3, and 4 with a representative percent of 8%, 44%, 36%, and 12 % respectively. For grading the samples, at least one tissue section of 5 μm thickness was stained with hematoxylin and eosin red stain. Results: There were 6,4 new cases of lymphoma per 100,000 people in Libya. This figure can be broken down into 3.8 NHL and 2.6 HL. Lymphoma incidence in the Libyan population is highly correlated with middle age, with almost 60% of cases occurring in those between 20 and 60 years old, with a mean age of 43. The total number of cases belonging to grade 1 was 6 cases (24%) divided into 4 (66.7%) in the coast region, 2 (33.3%) in the mountain region, and 0 cases in the south region. Grade 3 was represented the higher number of patients with 10 patients (40%) as compared with grade 2 (8 cases, 32%) and grade 4 (1 case, 4%) and most patients were located in the coast region. Additionally, the number of patients with NHL was 18 (72%) divided into 14 (77.8%) in the coast region, 2 (11%) in the mountain region, and 2 (11%) in the south whereas the number of patients with HL was 7 (28%) divided into 6 (85%) in coast region and 1 (14.3%) in the south region with no HL cases in mountain region. Conclusion: The results suggest the importance of achieving more studies in the future to explore the risk factors behind the prevalence of such type of blood cancer in Libya. (Open J Bio Med Res 2022;1:28-32.)","PeriodicalId":170585,"journal":{"name":"Open Journal of Biomedical Research","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115290798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The side effects of COVID-19 vaccines: A cross-sectional study in the eastern region of Libya","authors":"Arwa Benkhaial, Asmaa A. Rabee, Raga A. Elzahaf, I. Elmahdi, Fatma Benkhaial, T. Meidan","doi":"10.26629/ojbr.2022.05","DOIUrl":"https://doi.org/10.26629/ojbr.2022.05","url":null,"abstract":"Purpose: Patient-reported data is an important source of safety information. The aim of this study was to describe the side effects of COVID-19 vaccines used in Libya, compare them, and find the association of these with different factors. Materials and Methods: A cross-sectional study was conducted in the eastern part of Libya. Adults who got one or two doses of any COVID-19 vaccine were included. The questionnaire was distributed online via social media, and also distributed as paper form to increase the responses. Results: In total, 1779 adults, (53.7%) females completed the questionnaire. The mean age of participants was 39.87±14.99. Generally, females experienced side effects slightly higher compared to males (75.7% and 68.8% respectively). Overall, the prevalence of side effects was slightly higher in participants aged ≤40 years compared to those aged >40 years (76.5% and 66.6% respectively). However, this difference was found to be statistically significant (p=0.001). The side effects were more common among those previously infected with COVID-19 than those not (78.5% and 21.5%, respectively; p=0.001). The side effects were more common among those, who received the Sputnik V and the Sinopharm vaccine compared to other types. The most common side effect was fever (41.1%), (47.3%) for the Sputnik V vaccine. Conclusion: The side effects of COVID-19 vaccines used in Libya are generally mild and selflimiting. The most common side effect was fever, which was more prominent among females and the younger age group of participants. Also, the side effects were more common among those, who received the Sputnik V vaccine. (Open J Bio Med Res 2022;1:19-27.)","PeriodicalId":170585,"journal":{"name":"Open Journal of Biomedical Research","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124952993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influence anaesthesia technician work in intensive care unit (ICU): Qualitative study","authors":"Dalal Almghairbi, Zenab Elfzzani","doi":"10.26629/ojbr.2022.04","DOIUrl":"https://doi.org/10.26629/ojbr.2022.04","url":null,"abstract":"Purpose: Anaesthesia technicians are part of the ICU medical team, their profession is critical to the healthcare environment for achievement and delivery of adequate care and they do the respiratory therapists jobs/roles as well. The aim of the current study was to find out factors affecting anaesthesia technicians working in ICU. Materials and Methods: This was a qualitative single center study utilizing focus-group interviews (FGI’s), and in-depth individual interviews. Twenty anaesthesia technicians working in the ICU were enrolled until data saturation was reached. Data were analyzed using Colaizz’s method. Results: Through data analysis, three themes including system-related factors, environmental-related factors, and individual-related factors were found. Conclusion: The present study provided clear understanding of factors affecting anaesthesia technician’s working in ICU and these were found to be longstanding. The factors included system, environmental and individual related. Utilizing the results of this study can help develop managerial programs for understanding the factor affecting anaesthesia technician and job satisfaction promotion. (Open J Bio Med Res 2022;1:12-18.)","PeriodicalId":170585,"journal":{"name":"Open Journal of Biomedical Research","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125349980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Welcome to the Open Journal of Biomedical Research: A new journal with new value! Contributors","authors":"","doi":"10.26629/ojbr.2022.01","DOIUrl":"https://doi.org/10.26629/ojbr.2022.01","url":null,"abstract":"","PeriodicalId":170585,"journal":{"name":"Open Journal of Biomedical Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122261701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of kidney functions among COVID-19 patients in Isolation Center, Zawia-Libya","authors":"A. Kharbash, Azhar Kabar, Z. Ammar, Safa Omran, Abdelmoez Eshrif, Mohamed Wadan, Alsadiq Abdullah, Abdurraouf Zaet","doi":"10.26629/ojbr.2022.03","DOIUrl":"https://doi.org/10.26629/ojbr.2022.03","url":null,"abstract":"Purpose: In December 2019, a coronavirus 2019 (COVID-19) outbreak was detected in Wuhan, Hubei Province, China, and soon expanded to neighboring countries. Although abrupt respiratory failure and diffuse alveolar damage were the most notable features, another organ involvement needs to be looked at further. This study aimed to investigate the renal function tests among COVID-19 patients. Materials and Methods: The study surveyed a total of 247 patients hospitalized with COVID-19 at an isolation center located in Zawia, Libya over one year during 2020 and 2021. Laboratory analysis was performed on Urea, creatinine, chloride (Cl), sodium (Na), and potassium (K) parameters. Pearson correlation coefficient and interpretation in SPSS were used to analyze all tested samples. Results: Male COVID-19 patients, in particular had higher levels of urea and creatinine levels than normal and there was a positive connection with the three elements, as well as a positive statistical significance (0.001) for all the renal function tests. Conclusion: COVID-19 patients increase all of the elements listed above, either directly or indirectly, which is why conservative measures are the mainstay of contemporary renal trauma treatment. (Open J Bio Med Res 2022;1:7-11) Keywords COVID-19, kidney function, Urea, Creatinine, Sodium, Potassium, and Chloride.","PeriodicalId":170585,"journal":{"name":"Open Journal of Biomedical Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130663009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}