Genetically Modified Plants and Beyond [Working Title]最新文献

Next Generation of Transgenic Plants: From Farming to Pharming 下一代转基因植物:从种植到种植

Genetically Modified Plants and Beyond [Working Title] Pub Date : 2022-01-24 DOI: 10.5772/intechopen.102004

Alp Ayan, S. Meriç, Tamer Gümüş, Ç. Atak

{"title":"Next Generation of Transgenic Plants: From Farming to Pharming","authors":"Alp Ayan, S. Meriç, Tamer Gümüş, Ç. Atak","doi":"10.5772/intechopen.102004","DOIUrl":"https://doi.org/10.5772/intechopen.102004","url":null,"abstract":"The number of approaches related to recombinant protein production in plants is increasing rapidly day by day. Plant-based expression offers a safe, cost-effective, scalable, and potentially limitless way to rapidly produce recombinant proteins. Plant systems, which have significant advantages over animal and yeast recombinant protein production systems, are particularly promising for the large-scale production of antibodies and therapeutic proteins. Molecular pharming with transgenic plant systems become prominent among other production systems with its low cost, absence of human or animal pathogen contaminants, and the ability to use post-translational modifications such as glycosylation. The ability to produce recombinant pharmaceutical proteins in plant seeds, plant cells and various plant tissues such as hairy roots and leaves, through the stable transformation of the nuclear genome or transient expression, allows for the establishment of different production strategies. In particular, the rapid production of candidate proteins by transient expression, which eliminates the need for lengthy transformation and regeneration procedures, has made plants an attractive bioreactor for the production of pharmaceutical components. This chapter aimsto exhibit the current plant biotechnology applications and transgenic strategies used for the production of recombinant antibodies, antigens, therapeutic proteins and enzymes, which are used especially in the treatment of various diseases.","PeriodicalId":159021,"journal":{"name":"Genetically Modified Plants and Beyond [Working Title]","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130072432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Genetic Modification and Application in Cassava, Sweetpotato and Yams 木薯、甘薯和山药的基因改造及其应用

Genetically Modified Plants and Beyond [Working Title] Pub Date : 2021-12-20 DOI: 10.5772/intechopen.101037

Prince Emmanuel Norman, Daniel K. Dzidzienyo, Kumba Yannah Karim, Aloysius A. Beah

{"title":"Genetic Modification and Application in Cassava, Sweetpotato and Yams","authors":"Prince Emmanuel Norman, Daniel K. Dzidzienyo, Kumba Yannah Karim, Aloysius A. Beah","doi":"10.5772/intechopen.101037","DOIUrl":"https://doi.org/10.5772/intechopen.101037","url":null,"abstract":"Cassava (Manihot esculenta Crantz), sweetpotato (Ipomoea batatas) and yams (Dioscorea spp.) are important root and tuber crops grown for food, feed and various industrial applications. However, their genetic gain potentials are limited by breeding and genetic bottlenecks for improvement of many desired traits. This book chapter covers the applications and potential benefits of genetic modification in breeding selected outcrossing root and tuber crops. It assesses how improvement of selected root and tuber crops through genetic modification overcomes both the high heterozygosity and serious trait separation that occurs in conventional breeding, and contributes to timely achievement of improved target traits. It also assesses the ways genetic modification improves genetic gain in the root and tuber breeding programs, conclusions and perspectives. Conscious use of complementary techniques such as genetic modification in the root and tuber breeding programs can increase the selection gain by reducing the long breeding cycle and cost, as well as reliable exploitation of the heritable variation in the desired direction.","PeriodicalId":159021,"journal":{"name":"Genetically Modified Plants and Beyond [Working Title]","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123733276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

GM Crops: The West versus the Rest 转基因作物:西方与其他地区

Genetically Modified Plants and Beyond [Working Title] Pub Date : 2021-10-11 DOI: 10.5772/intechopen.100198

J. Thomson

引用次数: 0

Proposed Revision of the National Gene Technology Scheme for Australia 澳大利亚国家基因技术计划的修订建议

Genetically Modified Plants and Beyond [Working Title] Pub Date : 2021-09-20 DOI: 10.5772/intechopen.99966

Robert R Redden

{"title":"Proposed Revision of the National Gene Technology Scheme for Australia","authors":"Robert R Redden","doi":"10.5772/intechopen.99966","DOIUrl":"https://doi.org/10.5772/intechopen.99966","url":null,"abstract":"Plant breeding was provided access to wider genetic variation through genetic modification (GM) of crops in the 1980s. This involved transfer of DNA between species, and introduction of new traits into domestic crops. Concerns were raised for the outcomes in food health and in the environment with GM crops, with the spectre of ‘Frankenstien’ foods and fear of the unknown. This led to widespread adoption of GM regulations based on the ‘Precautionary principle’ of safeguarding the risks to health and to the environment, even when scientific evidence was lacking to support these concerns. The Green lobby required GM foods to be safe for consumption, with no ill-effects over the long term and for many generations into the future. GM foods have proven safe for over two decades, and with benefits to crop productivity, pest and disease resistances, improved nutrition and tolerances of extreme climatic stresses. GM includes the new biotechnology of Genome Editing (GE), with targeted and precise changes to gene sites, and inter-specific transfer of genes from poorly accessible Crop Wild Relatives (CRW), for adaptation of crops to climate change. Food and fibre crops need to be exempt from GM regulations.","PeriodicalId":159021,"journal":{"name":"Genetically Modified Plants and Beyond [Working Title]","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116210203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0