RADS Journal of Pharmacy and Pharmaceutical Sciences最新文献

Knowledge, Attitude and Practice Regarding Herbal Medicine Among Medical Students in Saudi Arabia 沙特阿拉伯医学生对草药的知识、态度和实践

RADS Journal of Pharmacy and Pharmaceutical Sciences Pub Date : 2021-06-25 DOI: 10.37962/jpps.v9i1.476

S. F. Zaidi, M. A. Khan, S. Saeed, Khalid Al Zahrani, Adel Al Ahmadi, Turky Al Yamy, Aslam Khan, Kanwal Ahmed

{"title":"Knowledge, Attitude and Practice Regarding Herbal Medicine Among Medical Students in Saudi Arabia","authors":"S. F. Zaidi, M. A. Khan, S. Saeed, Khalid Al Zahrani, Adel Al Ahmadi, Turky Al Yamy, Aslam Khan, Kanwal Ahmed","doi":"10.37962/jpps.v9i1.476","DOIUrl":"https://doi.org/10.37962/jpps.v9i1.476","url":null,"abstract":"Background: Herbal medicine is becoming increasingly popular among the general population. Before consulting a medical practitioner, patients already try home remedies. Therefore, it becomes more pertinent that the medical students as future doctors, must possess some knowledge of the herbal medicine. In Saudi Arabia, no study has yet evaluated this aspect in medical students. \u0000Methods: A cross-sectional study was performed with 240 medical students at a Health Sciences University. The survey questionnaire was validated, and descriptive/inferential statistics analyses were conducted by SPSS. \u0000Results: Data showed 50/240 students (20.8 %) used herbal medicines and majority 36 (72%) used it without consultation with doctors. Moreover, male understanding of the sources of herbal medicine was less compared to females' (p < 0.05). In terms of attitude, majority agreed with the benefits of herbal medicines in the maintenance and promotion of health (123, 51.3%) and to treat illness (127, 52.9%). However, medical students did not want to use herbal medicines (122, 50.8%) or recommend it to their families (161, 67.1%). A significant number of the respondents (160, 66.7%) opined that the herbal medicines could be taken with conventional or allopathic medications. Male students were significantly more inclined towards use of herbal medicine than their female counterparts (p < 0.05). \u0000Conclusion: Medical students were found to be unaware of some important aspects regarding herbal medicines, like use of herbs with drugs without consultation. Inclusion of proper courses on alternative medicine in medical curriculum can fill this gap and clarify the misconceptions among medical students.","PeriodicalId":154639,"journal":{"name":"RADS Journal of Pharmacy and Pharmaceutical Sciences","volume":"133 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127331730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Prognosis and the Global Impact of the COVID-19 Pandemic - A Comprehensive Review COVID-19大流行的预后和全球影响——综合综述

RADS Journal of Pharmacy and Pharmaceutical Sciences Pub Date : 2021-06-25 DOI: 10.37962/jpps.v9i1.487

S. Zainab, Syed Muhammad Farid Hassan, Rabia Noor, F. Khalid, Monica Parkash J. Ojha

{"title":"Prognosis and the Global Impact of the COVID-19 Pandemic - A Comprehensive Review","authors":"S. Zainab, Syed Muhammad Farid Hassan, Rabia Noor, F. Khalid, Monica Parkash J. Ojha","doi":"10.37962/jpps.v9i1.487","DOIUrl":"https://doi.org/10.37962/jpps.v9i1.487","url":null,"abstract":"Background: The novel coronavirus 2019 or SARS-CoV-2 appeared first in the December, 2019, in the Wuhan, China. The virus later effected almost every part of the world. \u0000Aim of the Review: The review is aimed to deliver a detailed prognosis of SARS-CoV-2 on basis of evaluation of different attributes of the virus reported or published. \u0000Method: Articles were searched on Google Scholar and PubMed databases. All articles concerning SARS-CoV-2 were included. The duplicate articles were identified with EndNote and excluded. Related data from WHO, FDA and CDC were also included. \u0000Results: The following parameters were found to show an important role in the prognosis of the SARS-CoV-2 i.e., physical properties, evolution, pathogenesis, epidemiology, demography, geography, diagnosis method, laboratory findings and clinical features. Moreover, several approaches were found to fight the viral infection including proposed therapies, proposed drugs, and vaccines. However, till the development of effective and safe approach the preventive measures are recommended to be strictly followed. \u0000Conclusion: The global impact of this virus is beyond reconciliation and rapprochement. Its impact on various major industries such as agriculture, petroleum & oil, manufacturing industry, education and healthcare, and the pharmaceutical industries is inexplicable.","PeriodicalId":154639,"journal":{"name":"RADS Journal of Pharmacy and Pharmaceutical Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129818304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Validation and Development of Analytical Technique for the Fast and Economical Evaluation of Amoxicillin in Solid Dosage form Through UV/Visible Spectroscopy 紫外/可见光谱法快速经济评价阿莫西林固体剂型分析技术的验证与发展

RADS Journal of Pharmacy and Pharmaceutical Sciences Pub Date : 2021-06-25 DOI: 10.37962/jpps.v9i1.472

M. Iqbal, S. S. Hassan, Muhammad Abbas, H. Ahmad

{"title":"The Validation and Development of Analytical Technique for the Fast and Economical Evaluation of Amoxicillin in Solid Dosage form Through UV/Visible Spectroscopy","authors":"M. Iqbal, S. S. Hassan, Muhammad Abbas, H. Ahmad","doi":"10.37962/jpps.v9i1.472","DOIUrl":"https://doi.org/10.37962/jpps.v9i1.472","url":null,"abstract":"Objective: The key objective of the study is to explore the sensitive, rapid, simple, accurate and economic UV/Vis spectrophotometric method to determine the amount of Amoxicillin trihydrate (AMTR) in bulk pharmaceuticals and in various formulations including dry powder (syrup), tablets and capsules by employing Copper sulphate buffer solution. \u0000Methodology: The current spectroscopic analysis performed with 12.5 μg/ml concentration of AMTR at 320 nm follows the Beer’s Lambert Law. The linearity range (10-15µg/ml) and regression data presented a significant correlation coefficient (r2 =0.999). The appropriate level of accuracy, precision, linearity, and mean percentage recovery of AMTR were found adequate relating to the % age error and standard deviations. \u0000Results: Amoxicillin trihydrate and its known strengths were scanned and analyzed by our validated method such as; 10.0 µg/ml Amoxicillin (80%), 11.25 µg/ml Amoxicillin (90%), 12.5 µg/ml Amoxicillin (100%), 13.75 µg/ml Amoxicillin (110%) and 15.0 µg/ml Amoxicillin (120%). \u0000Conclusions: As the recommended protocol of amoxicillin determination (spectrophotometry) is accurate, precise and statistically evaluated, therefore it could readily be employed for qualitative purposes of either for the raw material and pharmaceutical preparations.","PeriodicalId":154639,"journal":{"name":"RADS Journal of Pharmacy and Pharmaceutical Sciences","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128503331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of SVR 12 in Hepatitis C Subjects Attending Tertiary Care Hospital in Lahore-Pakistan: an Observational Data 在巴基斯坦拉合尔三级医院就诊的丙型肝炎患者SVR - 12的有效性:一项观察性数据

RADS Journal of Pharmacy and Pharmaceutical Sciences Pub Date : 2021-06-25 DOI: 10.37962/jpps.v9i1.448

M. Abbasi, A. Farooq, M. B. Khawar, Nasir Yousaf, Muhammad Khalil Ahmad Khan, S. Fatima, N. Sheikh

{"title":"Effectiveness of SVR 12 in Hepatitis C Subjects Attending Tertiary Care Hospital in Lahore-Pakistan: an Observational Data","authors":"M. Abbasi, A. Farooq, M. B. Khawar, Nasir Yousaf, Muhammad Khalil Ahmad Khan, S. Fatima, N. Sheikh","doi":"10.37962/jpps.v9i1.448","DOIUrl":"https://doi.org/10.37962/jpps.v9i1.448","url":null,"abstract":"Introduction: In Pakistan, for the patients of Hepatitis C virus (HCV), Direct-Acting Antiviral (DAA) therapy for 12 weeks and 24 weeks had been reported to be highly efficacious for genotype 3. We currently carried out an observational study to predict the rate of efficacy of sofosbuvir and ribavirin in hepatitis C patients to establish concrete or authentic data on this combination of DAA for long-term treatment. \u0000Materials and Method: Among 2000 subjects who attended tertiary care unit in Lahore-Pakistan from November 2018 to February 2019, 1990 satisfied the criteria set for the present investigation i.e. SVR12 after being treated with sofosbuvir and ribavirin combination. \u0000Results: It was noted that genotype 3a were more common among all the subjects under observation with 50.65 % (1008/1990) in females and 49.35% (982/1990) in males. Overall efficacy analysis was found to be 95.4% (1900/1990) in patients while the moderate response was noted in elderly subjects including both genders (61-90 years). DAA responders (male: female percentages) shown the following stats; 66.63 (42/66):36.36 (24/66) in 11-20 years, 56.6(240/424):43.39 (184/424) in 21-30 years and 44.73(272/608):55.27(336/608) in 31-40 years. \u0000Conclusion: Collectively, this combinational drug therapy was observed to be successful among the Pakistani population. However, more comprehensive follow-up studies are needed on a larger pool of population nationwide to check only this combinational therapy (sofosbuvir and ribavirin) would be beneficial or not? Or next-generation DAA regimes would be the choice for the Pakistani population.","PeriodicalId":154639,"journal":{"name":"RADS Journal of Pharmacy and Pharmaceutical Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125514462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between Sonographic Findings of Maternal Thyroid Gland and Thyroid Function Tests during Pregnancy 妊娠期间母体甲状腺超声表现与甲状腺功能检查的相关性

RADS Journal of Pharmacy and Pharmaceutical Sciences Pub Date : 2021-01-28 DOI: 10.37962/JPPS.V8I3.445

Maimoona Rasool, Sarah Maryam, M. Noor, M. Fatima, S. Ayaz, M. Younis, Syed Amir Gilani, R. Bacha, Maria Rasool, Sadaf Ayesha, M. Farooq

{"title":"Correlation between Sonographic Findings of Maternal Thyroid Gland and Thyroid Function Tests during Pregnancy","authors":"Maimoona Rasool, Sarah Maryam, M. Noor, M. Fatima, S. Ayaz, M. Younis, Syed Amir Gilani, R. Bacha, Maria Rasool, Sadaf Ayesha, M. Farooq","doi":"10.37962/JPPS.V8I3.445","DOIUrl":"https://doi.org/10.37962/JPPS.V8I3.445","url":null,"abstract":"Background: Pregnancy has great influence on maternal thyroid gland. It induces significant physiological as well as hormonal changes that alters the maternal thyroid function. Our goal was to determine this pregnancy associated changes in thyroid gland. \u0000Objective: To correlate the sonographic findings of maternal thyroid gland with thyroid function tests during pregnancy. \u0000Material and methods: 135 pregnant women were recruited in this study, data of TSH, T3 and T4 was obtained and correlated it with the sonographic findings of maternal thyroid gland in each trimester of pregnancy. \u0000Results: In the 135 sampled pregnant women, mean thyroid gland volume was 4.08±1.19 cm3. The mean levels of T3, T4 and TSH were v3.37±.44 pmol/L, 14.96±2.49 pmol/L and 1.21±.92 mIU/L respectively. A remarkable correlation between thyroid hormones and thyroid volume was observed. \u0000Conclusion: It is concluded that the ultra-sonographic findings is correlated with the thyroid function tests during pregnancy.","PeriodicalId":154639,"journal":{"name":"RADS Journal of Pharmacy and Pharmaceutical Sciences","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117159813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frequency of Thyrotoxicosis in Patient with One Sided Exophthalmos 单侧突出眼甲状腺毒症的发生率

RADS Journal of Pharmacy and Pharmaceutical Sciences Pub Date : 2020-11-11 DOI: 10.37962/jpps.v8i2.373

Tahreem Zafar, Shumaila Perveen, N. Khan, Salman Khan, Tahseen Ahmed

{"title":"Frequency of Thyrotoxicosis in Patient with One Sided Exophthalmos","authors":"Tahreem Zafar, Shumaila Perveen, N. Khan, Salman Khan, Tahseen Ahmed","doi":"10.37962/jpps.v8i2.373","DOIUrl":"https://doi.org/10.37962/jpps.v8i2.373","url":null,"abstract":"Background: Thyroid associated Opthalmo-pathy is a condition of lid retraction causing a staring appearance. This occurs in any form of thyrotoxicosis as a result of sympathetic overactivity.Exophthalmos is the forward protrusion of eye ball beyond the orbital rim. \u0000Material & Methods: This case series was observed in medical department Mufti Mehmood Teaching Hospital DIKhan, Pakistan over a period of eight months from February 2018 to September 2018. Detailed history with reference of duration of illness, mode of onset, progression and associated symptoms like fever, pain, diplopia and loss of vision was taken. Complete examination of orbit, eyelid, anterior and posterior segment was done. Routine Investigations along with special diagnostic tests like TFTs and MRI were performed to aid etiological diagnosis. \u0000Results: A total 47 patients were observed during this study period. Out of these 20 (21.27%) were male and 27 (57.44%) were female with male to female ratio 1:1.35 with mean age of 32 years. Out of 47 patients30 (63.82%) patients were having thyrotoxicosis as a cause of exophthalmos, 10(21.27%) were having retrobulbartumour, 5(10.63%) patients were with cavernous sinus thrombosis and 2(4.25%) patients were having idiopathic cause of exophthalmos. \u0000Conclusion: Thyrotoxicosis is the common cause of one sided exophthalmos and should be considered in all patients with one sided exophthalmos.","PeriodicalId":154639,"journal":{"name":"RADS Journal of Pharmacy and Pharmaceutical Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129211263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-Epileptic Potential of Ziziphus Vulgaris and Ferula Asafoetida Extracts in Drug Induced Seizure Models of Experimental Mice 酸枣和阿魏提取物对实验性小鼠药物性癫痫模型的抗癫痫作用

RADS Journal of Pharmacy and Pharmaceutical Sciences Pub Date : 2020-09-04 DOI: 10.37962/jpps.v8i1.344

N. Anwar, M. A. Khan, Mehwish Bukhari, Hammad Ahmed, A. A. Zaidi, Haroon Arshad

{"title":"Anti-Epileptic Potential of Ziziphus Vulgaris and Ferula Asafoetida Extracts in Drug Induced Seizure Models of Experimental Mice","authors":"N. Anwar, M. A. Khan, Mehwish Bukhari, Hammad Ahmed, A. A. Zaidi, Haroon Arshad","doi":"10.37962/jpps.v8i1.344","DOIUrl":"https://doi.org/10.37962/jpps.v8i1.344","url":null,"abstract":"Background: Ziziphus vulgaris (ZV) and Ferula asafoetida (FA) have phenolic compounds with potential anti-epileptic activity. \u0000Objective: This study was aimed to investigate the anti-epileptic potential of hydroalcoholic (30:70) crude extracts of ZV and FA. \u0000Methods: Different doses (5 mg/ml, 15 mg/ml, 25 mg/ml) of extracts from ZV and FA were separately administered intraperitoneally to groups (7/group) of male albino mice (20-30 g). Phenytoin (15 mg/ml, intraperitoneal) was used as positive control. After 30 min, tonic-clonic seizures were induced by intraperitoneal administration of picrotoxin (6 mg/ml) and strychnine (4 mg/ml) in separate groups. Animals were monitored for 1 h and different parameters including onset and frequency of seizures and protection (against mortality & seizures) were determined. \u0000Results: A dose dependent significant delay in onset and decrease in seizure frequency as well as mortality was observed in animals treated with plant extracts (ZV and FA). Positive control (phenytoin) also showed significant delay in seizure onset and decreased the seizure frequency. \u0000Conclusion: The plant extracts (ZV and FA) contain the phenolic compounds which may induce the GABAergic transmission that could be the most probable mechanism for their anti-epileptic activity. Molecular studies and histopathological analysis are required to elucidate the exact anti-epileptic mechanisms of ZV and FA extracts.","PeriodicalId":154639,"journal":{"name":"RADS Journal of Pharmacy and Pharmaceutical Sciences","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123798618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Knowledge and Practices of Voluntary Blood Donation Among Pharmacy Students; A Cross-Sectional Survey from Lahore, Pakistan 药学专业学生无偿献血知识与实践的评估巴基斯坦拉合尔的横断面调查

RADS Journal of Pharmacy and Pharmaceutical Sciences Pub Date : 2020-01-30 DOI: 10.37962/jpps.v7i4.337

R. Asghar, Nageen Zeeshan, A. Sohaib, A. Munir, Muhammad Amjad, Sharjeel Ahmad, Jamshaid Akbar

{"title":"Assessment of Knowledge and Practices of Voluntary Blood Donation Among Pharmacy Students; A Cross-Sectional Survey from Lahore, Pakistan","authors":"R. Asghar, Nageen Zeeshan, A. Sohaib, A. Munir, Muhammad Amjad, Sharjeel Ahmad, Jamshaid Akbar","doi":"10.37962/jpps.v7i4.337","DOIUrl":"https://doi.org/10.37962/jpps.v7i4.337","url":null,"abstract":"Objective: To determine the current knowledge and practices regarding voluntary blood donation among pharmacy (Pharm-D) students of Lahore, Pakistan. \u0000Methods: A cross-sectional quantitative survey was performed among Pharm-D students of two private and two public sector universities of Lahore, Pakistan in January 2018. Total 600 students were included in the study by convenient sampling technique. Data was gathered by a self-administered well-designed questionnaire and was analyzed by using SPSS version 23. \u0000Results: The level of knowledge among majority respondents (61.3%) about different aspects of blood donation was found to be good. The results revealed that despite having good knowledge, a significant number of the respondents (65.2%) were not practicing blood donation. The major reasons identified for poor blood donation practice were inconvenient environment and lack of facilities for the donors. \u0000Conclusion: There exists a gap in converting the good knowledge of respondents into practice of voluntary blood donation. Effective programs should be initiated to promote and aware people regarding the necessity of blood donation.","PeriodicalId":154639,"journal":{"name":"RADS Journal of Pharmacy and Pharmaceutical Sciences","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132237909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0