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Evan’s syndrome, primary or secondary? Navigating the diagnostic puzzle 埃文综合征，原发性还是继发性？破解诊断难题
Physician's Journal of Medicine Pub Date : 2024-05-21 DOI: 10.55070/wnqa2094
Salman Khan, George Khatar, Ekrem Yetiskul, Malik Waleed Zeb Khan, Faris Qaqish, Yisroel Grabie, Aqsa Nisar, Ngowari Pokima, Muhammad Niazi
{"title":"Evan’s syndrome, primary or secondary? Navigating the diagnostic puzzle","authors":"Salman Khan, George Khatar, Ekrem Yetiskul, Malik Waleed Zeb Khan, Faris Qaqish, Yisroel Grabie, Aqsa Nisar, Ngowari Pokima, Muhammad Niazi","doi":"10.55070/wnqa2094","DOIUrl":"https://doi.org/10.55070/wnqa2094","url":null,"abstract":"Evans syndrome (ES) is a rare autoimmune disorder characterized by the simultaneous or sequential occurrence of autoimmune hemolytic anemia (AIHA) and immune thrombocytopenic purpura (ITP). Distinguishing between primary and secondary forms is crucial for management. This report presents a 69-year-old male with bleeding gums, anemia, and thrombocytopenia, who was diagnosed with ES following an extensive workup. Multiple potential triggers, including recent vaccinations, antibiotic use, past tuberculosis, and skin malignancies, were identified, highlighting the multifactorial nature of ES. The patient was treated with glucocorticoids, intravenous immunoglobulin (IVIG), Rituximab, and Romiplostim resulting in improved hematologic parameters. This case underscores the diagnostic challenges and importance of individualized therapeutic approaches in managing ES. Understanding the potential triggers and underlying immune dysregulation is pivotal for accurate diagnosis and effective treatment.","PeriodicalId":137903,"journal":{"name":"Physician's Journal of Medicine","volume":"21 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141117378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sometimes Things Are Not Where They Are Supposed to Be: A Case Report of Gastric Heterotopia in the Rectum 有时事情不在他们应该在的地方:直肠胃异位一例报告
Physician's Journal of Medicine Pub Date : 2022-12-21 DOI: 10.55070/pjom.v1i1.17
Asher Lippe, S. Lippe
{"title":"Sometimes Things Are Not Where They Are Supposed to Be: A Case Report of Gastric Heterotopia in the Rectum","authors":"Asher Lippe, S. Lippe","doi":"10.55070/pjom.v1i1.17","DOIUrl":"https://doi.org/10.55070/pjom.v1i1.17","url":null,"abstract":"While gastric heterotopia has been described as occurring anywhere throughout the gastrointestinal tract, an asymptomatic finding in the rectum is exceedingly rare. Gastric heterotopia happens when gastric mucosa arrives in the wrong section of the GI tract during early fetal development. This condition can be asymptomatic or symptomatic, depending on the production of gastric acid and its effects on surrounding tissues. The presence of gastric heterotopia in an unfamiliar location can surprise the clinician with an unusual-appearing lesion. Its symptomology can also lead to unusual complaints whose etiology is only elucidated after biopsies. We report a rare case of a spread-out rectal lesion with heaped-up borders in an asymptomatic female who underwent colonoscopy screening.","PeriodicalId":137903,"journal":{"name":"Physician's Journal of Medicine","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127437581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osteonecrosis secondary to covid and its possible association to the cardiovascular system: a case report. covid继发性骨坏死及其与心血管系统的可能关联:1例报告
Physician's Journal of Medicine Pub Date : 2022-09-23 DOI: 10.55070/pjom.v1i1.13
Gedaliah May, Daniel J. Fuchs, Daniella Miller, G. Saffran
{"title":"Osteonecrosis secondary to covid and its possible association to the cardiovascular system: a case report.","authors":"Gedaliah May, Daniel J. Fuchs, Daniella Miller, G. Saffran","doi":"10.55070/pjom.v1i1.13","DOIUrl":"https://doi.org/10.55070/pjom.v1i1.13","url":null,"abstract":"Avascular necrosis (AVN) also referred to as osteonecrosis (ON) refers to inadequate perfusion to bone tissue resulting in death or necrosis of the bone. Although many known risk factors and etiologies exist, 20%-40% of AVN cases are idiopathic (1). There have been reported cases of osteonecrosis secondary to Covid-19 infection. However, these cases are typically attributed to the steroids used in the treatment plan of the viral infection. Here, we describe a case of idiopathic osteonecrosis attributed to a Covid-19 infection where the patient was not treated with steroids. We discuss a possible relationship between AVN and the cardiovascular system that may reflect an underlying cause contributing to avascular necrosis and Covid-19. ","PeriodicalId":137903,"journal":{"name":"Physician's Journal of Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114601440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recommendations for Gastric Cancer Screening in Korean Americans 韩裔美国人胃癌筛查的建议
Physician's Journal of Medicine Pub Date : 2022-09-01 DOI: 10.55070/pjom/101
Asher Lippe, S. Lippe
{"title":"Recommendations for Gastric Cancer Screening in Korean Americans","authors":"Asher Lippe, S. Lippe","doi":"10.55070/pjom/101","DOIUrl":"https://doi.org/10.55070/pjom/101","url":null,"abstract":"In the United States, Korean Americans have the highest incidence rate of gastric cancer and have a five times higher risk than non-Hispanic Whites. Early detection is important for cancer treatment and survival.  In countries where there is a high prevalence of gastric cancer, such as Korea and Japan, national screening programs have been implemented. In the United States, immigrants of countries like Korea and Japan continue to have many of the same risk factors as in their home country.  However, recommendations for gastric cancer screening in the United States are lacking, even for these high-risk populations. We conducted a literature search of relevant information to identify appropriate screening measures and criteria for gastric cancer screening for Korean Americans. Based on the data from the Korean national screening program, the proportion of gastric cancers diagnosed at an earlier stage increased significantly. Furthermore, endoscopic screening was associated with a decrease of about 50% in gastric cancer death risk for those between 40 and 74 years old. Therefore, there is a similar need for screening for Korean Americans who have a similar diet and lifestyle as native Koreans. By increasing early detection, routine screening via endoscopy in high-risk Korean Americans may have a significant impact on decreasing the morbidity and mortality associated with gastric cancer, as seen in the Korean studies.","PeriodicalId":137903,"journal":{"name":"Physician's Journal of Medicine","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127516648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Amygdala’s Role in Panic Attacks Panic’s Relationship with The Brain 杏仁核在恐慌发作中的作用恐慌与大脑的关系
Physician's Journal of Medicine Pub Date : 2022-01-19 DOI: 10.55070/2224
Tova Boiangiu
{"title":"The Amygdala’s Role in Panic Attacks Panic’s Relationship with The Brain","authors":"Tova Boiangiu","doi":"10.55070/2224","DOIUrl":"https://doi.org/10.55070/2224","url":null,"abstract":"","PeriodicalId":137903,"journal":{"name":"Physician's Journal of Medicine","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127349325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE TRUTH ABOUT ANTIBACTERIAL PRODUCTS AND ANTIBIOTICS 关于抗菌产品和抗生素的真相
Physician's Journal of Medicine Pub Date : 2022-01-19 DOI: 10.55070/00009
A. Hassan
{"title":"THE TRUTH ABOUT ANTIBACTERIAL PRODUCTS AND ANTIBIOTICS","authors":"A. Hassan","doi":"10.55070/00009","DOIUrl":"https://doi.org/10.55070/00009","url":null,"abstract":"","PeriodicalId":137903,"journal":{"name":"Physician's Journal of Medicine","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125397245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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