Journal of Brachial Plexus and Peripheral Nerve Injury (JBPPNI)最新文献

Large Cervical Vagus Nerve Tumor in a Patient with Neurofibromatosis Type 1 Treated with Gross Total Resection: Case Report and Review of the Literature 1型神经纤维瘤病大颈迷走神经肿瘤行全切除1例报告及文献复习

Journal of Brachial Plexus and Peripheral Nerve Injury (JBPPNI) Pub Date : 2016-11-16 DOI: 10.1055/s-0036-1594010

David P. Bray, A. Chan, C. Chin, L. Jacques

引用次数: 9

The Influence of Glutamate on Axonal Compound Action Potential In Vitro 谷氨酸对体外轴突复合动作电位的影响

Journal of Brachial Plexus and Peripheral Nerve Injury (JBPPNI) Pub Date : 2016-10-24 DOI: 10.1055/s-0036-1593441

Ahmed Abouelela, A. Wieraszko

{"title":"The Influence of Glutamate on Axonal Compound Action Potential In Vitro","authors":"Ahmed Abouelela, A. Wieraszko","doi":"10.1055/s-0036-1593441","DOIUrl":"https://doi.org/10.1055/s-0036-1593441","url":null,"abstract":"Abstract Background Our previous experiments demonstrated modulation of the amplitude of the axonal compound action potential (CAP) by electrical stimulation. To verify assumption that glutamate released from axons could be involved in this phenomenon, the modification of the axonal CAP induced by glutamate was investigated. Objectives The major objective of this research is to verify the hypothesis that axonal activity would trigger the release of glutamate, which in turn would interact with specific axonal receptors modifying the amplitude of the action potential. Methods Segments of the sciatic nerve were exposed to exogenous glutamate in vitro, and CAP was recorded before and after glutamate application. In some experiments, the release of radioactive glutamate analog from the sciatic nerve exposed to exogenous glutamate was also evaluated. Results The glutamate-induced increase in CAP was blocked by different glutamate receptor antagonists. The effect of glutamate was not observed in Ca-free medium, and was blocked by antagonists of calcium channels. Exogenous glutamate, applied to the segments of sciatic nerve, induced the release of radioactive glutamate analog, demonstrating glutamate-induced glutamate release. Immunohistochemical examination revealed that axolemma contains components necessary for glutamatergic neurotransmission. Conclusion The proteins of the axonal membrane can under the influence of electrical stimulation or exogenous glutamate change membrane permeability and ionic conductance, leading to a change in the amplitude of CAP. We suggest that increased axonal activity leads to the release of glutamate that results in changes in the amplitude of CAPs.","PeriodicalId":131511,"journal":{"name":"Journal of Brachial Plexus and Peripheral Nerve Injury (JBPPNI)","volume":"307 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114711119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Self-Concept and Emotional-Behavioral Functioning of Children with Brachial Plexus Birth Injury 臂丛出生损伤患儿自我概念及情绪行为功能评价

Journal of Brachial Plexus and Peripheral Nerve Injury (JBPPNI) Pub Date : 2016-10-24 DOI: 10.1055/s-0036-1593440

Lori A Belfiore, C. Rosen, Rachel Sarshalom, L. Grossman, D. Sala, J. Grossman

{"title":"Evaluation of Self-Concept and Emotional-Behavioral Functioning of Children with Brachial Plexus Birth Injury","authors":"Lori A Belfiore, C. Rosen, Rachel Sarshalom, L. Grossman, D. Sala, J. Grossman","doi":"10.1055/s-0036-1593440","DOIUrl":"https://doi.org/10.1055/s-0036-1593440","url":null,"abstract":"Abstract Background The reported incidence of brachial plexus birth injury (BPBI) is 0.87 to 2.2 per 1,000 live births. The psychological functioning, including self-concept and emotional-behavioral functioning, of children with BPBI has only been examined to a limited extent. Objective The purpose of this study was to describe the self-concept and emotional-behavioral functioning in children with BPBI from both the child's and parent's perspective. Methods Thirty-one children with BPBI, mean age 11 years 1 month, completed the Draw A Person: Screening Procedure for Emotional Disturbance (DAP:SPED) and Piers Harris Children's Self-Concept Scale (PHCSCS). The parents answered questions from the Behavior Assessment System for Children, Parent Rating Scales (BASC-2 PRS). Results The scores from the DAP:SPED drawings showed further evaluation was not strongly indicated in the majority of the children. The PHCSCS Total score demonstrated that the children had a strongly positive self-concept. The parental responses to the BASC-2 PRS indicated that few children were at risk or in the clinically significant range for the four composite scores and all of the component clinical or adaptive scales. Gender comparison revealed females exhibited greater anxiety than males. Conclusion Both children and parents reported a positive psychological well-being for the majority of the children. Parents had greater concerns about their child's social-emotional functioning, particularly anxiety. An interdisciplinary approach (occupational therapy evaluation, clinical observation, and parental interview) is necessary to determine the need for mental health referral.","PeriodicalId":131511,"journal":{"name":"Journal of Brachial Plexus and Peripheral Nerve Injury (JBPPNI)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124403272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

A Vascular Malformation Presenting as a Peripheral Nerve Sheath Tumor 表现为周围神经鞘肿瘤的血管畸形

Journal of Brachial Plexus and Peripheral Nerve Injury (JBPPNI) Pub Date : 1900-01-01 DOI: 10.1055/s-0036-1593442

Vikas K. Parmar, C. Haldeman, Steve Amaefuna, Amgad S. Hanna

引用次数: 5