DeckerMed Nephrology, Dialysis, and Transplantation最新文献

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Kidney Biopsy 肾活检

DeckerMed Nephrology, Dialysis, and Transplantation Pub Date : 2020-12-01 DOI: 10.2310/nephro.12031

A. Voiculescu, G. McMahon

{"title":"Kidney Biopsy","authors":"A. Voiculescu, G. McMahon","doi":"10.2310/nephro.12031","DOIUrl":"https://doi.org/10.2310/nephro.12031","url":null,"abstract":"The introduction of renal biopsies has transformed practice in nephrology, particularly with regard to glomerular disease and the care of kidney transplant recipients. A biopsy can provide information about the diagnosis and prognosis of kidney disease while most importantly often leading to changes in therapy that can be life saving. Four groups of patients benefit most from renal biopsy: those with nephrotic syndrome, those with acute nephritic syndromes with rapid deterioration of renal function, those with unexplained acute kidney injury and renal transplant recipients. Non-nephrotic range proteinuria and/or hematuria or unexplained chronic kidney disease represent indications in selected cases. The evaluation of patients prior to undergoing a kidney biopsy requires a careful assessment that includes a detailed history to confirm the relative benefit of a biopsy in making an accurate diagnosis compared with individual’s risk of bleeding. The use of real-time ultrasound or CT-guidance with gun-mounted biopsy needles is paramount for the successful performance of the biopsy and reduction of risks. renal biopsies are mostly done as an inpatient but can be performed on an outpatient basis in selected cases. A renal biopsy has a bleeding risk of up to 5% and is considered a “high bleeding risk procedure”. For patients receiving -antithrombotic therapy, the approach to periprocedural use of antithrombotic agents needs to be individualized. Because it is a high-risk procedure, all efforts must be undertaken to minimize the risk including a careful assessment of the patient's specific situation, and only experienced operators at institutions that can care for post-biopsy complications should perform the procedure.\u0000This review contains 7 tables, 7 figures and 83 references\u0000Key words: kidney biopsy, native kidney, transplant kidney, indications, preparation, performing biopsy, ultrasound guidance, transjugular, CT-guided, complications","PeriodicalId":126181,"journal":{"name":"DeckerMed Nephrology, Dialysis, and Transplantation","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130671725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Peritoneal Dialysis 腹膜透析

DeckerMed Nephrology, Dialysis, and Transplantation Pub Date : 2019-10-29 DOI: 10.2310/nephro.12057

K. François, J. Bargman

引用次数: 0

Hematologic Abnormalities in Chronic Kidney Disease 慢性肾病的血液学异常

DeckerMed Nephrology, Dialysis, and Transplantation Pub Date : 2018-06-14 DOI: 10.2310/nephro.1370

M. Auerbach, John V. Anderson, K. Al Talib

{"title":"Hematologic Abnormalities in Chronic Kidney Disease","authors":"M. Auerbach, John V. Anderson, K. Al Talib","doi":"10.2310/nephro.1370","DOIUrl":"https://doi.org/10.2310/nephro.1370","url":null,"abstract":"The focus of this review is on information practical to the practicing nephrologist and internists managing patients with chronic kidney disease (CKD), with an emphasis on the quantitative aspects of risk, diagnosis, treatment, and prognosis. Consequently, anemia associated with non–dialysis-associated CKD is emphasized, with special attention to the role of erythropoiesis-stimulating agents and intravenous (IV) iron in treating the anemia of CKD, as well as sections on uremic bleeding and anticoagulation in CKD patients. Figures show a patient before and after a minor infusion reaction, an algorithm outlining grading and management of acute hypersensitivity reactions to IV iron infusions, and an algorithm for the management of uremic platelet dysfunction. Tables list Food and Drug Administration-recommended dose adjustments for novel oral anticoagulant (NOACs) in CKD patients, evidence for preprocedural withholding of NOACs, and management guidelines for anticoagulation in nonvalvular atrial fibrillation and venous thromboembolism.\u0000This review contains 2 highly rendered figures, 3 tables, and 101 references.\u0000Key words: Chronic kidney disease; CKD; Anemia of chronic kidney disease; Anemia of CKD; Uremic bleeding; Anticoagulation in CKD; Novel oral anticoagulants in CKD; NOAC CKD","PeriodicalId":126181,"journal":{"name":"DeckerMed Nephrology, Dialysis, and Transplantation","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127742968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0