发布求助
文献互助 智能选刊 最新文献

ChemRN: Medicinal Chemistry (Topic)最新文献

筛选
英文 中文
PHYSALIS ALKEKENGI VA PHYSALIS ANGULATA O’SIMLIKLARI FITOKIMYOVIY TARKIBI (Phytochemical Composition of Physalis alkekengi and Physalis angulata Plants) ALKEKENGI VA PHYSALIS ANGULATA O 'SIMLIKLARI FITOKIMYOVIY TARKIBI (PHYSALIS ALKEKENGI和PHYSALIS ANGULATA植物的植物化学成分)
ChemRN: Medicinal Chemistry (Topic) Pub Date : 2020-11-21 DOI: 10.2139/ssrn.3741988
Izzatullo Lutfulloyevich Xikmatullayev, Vahobjon Umarovich Xo’jayev
{"title":"PHYSALIS ALKEKENGI VA PHYSALIS ANGULATA O’SIMLIKLARI FITOKIMYOVIY TARKIBI (Phytochemical Composition of Physalis alkekengi and Physalis angulata Plants)","authors":"Izzatullo Lutfulloyevich Xikmatullayev, Vahobjon Umarovich Xo’jayev","doi":"10.2139/ssrn.3741988","DOIUrl":"https://doi.org/10.2139/ssrn.3741988","url":null,"abstract":"Uzbek abstract: O’zbekistonda farmatsevtika sanoatimiz uchun xom ashyo manbalarini kengaytirish va shu \u0000bilan ichki daromadimizni oshirish uchun o'simlik turlarini tadqiq etishni kuchaytirish zarur. \u0000Shuning uchun ushbu maqolada Physalis angulata va Physalis alkekengi o’simliklari fitokimyoviy \u0000tarkibi va fiziologik faolligi to’g’risidagi ma’lumotlar umumlashtirilgan. \u0000 \u0000English abstract: In Uzbekistan, it is necessary to expand the sources of raw materials for our pharmaceutical industry and thus strengthen the study of plant species to increase our domestic income. Therefore, this article summarizes the phytochemical composition and physiological activity of the plants Physalis angulata and Physalis alkekengi.","PeriodicalId":121861,"journal":{"name":"ChemRN: Medicinal Chemistry (Topic)","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127113179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Mathematical Review to Estimate the Fate of a Drug Following Open Two Compartment Model, When it is Administered by Intravenous Route 通过静脉给药途径估计药物命运的两室开放模型的数学回顾
ChemRN: Medicinal Chemistry (Topic) Pub Date : 2020-06-01 DOI: 10.22377/ajms.v4i3.280
S. Dey
{"title":"A Mathematical Review to Estimate the Fate of a Drug Following Open Two Compartment Model, When it is Administered by Intravenous Route","authors":"S. Dey","doi":"10.22377/ajms.v4i3.280","DOIUrl":"https://doi.org/10.22377/ajms.v4i3.280","url":null,"abstract":"This paper deals with the application of Laplace Transform [L(f)(s) = F(s) = e-ts f(t)dt] to derive theformula [(Cp \u0000(t)= Ae-at+ Be-bt] and [Ct \u0000(t)= Te-bt-Te-at] to estimate the fate of a drug in the mammillary bodywith the prediction of the biological parameters [k, k12, and k21]. The numerical values of [k, k12, and k21]which is estimated through the determination of the mathematical hybrid constants (A, B, a, b, T) alsopredict the tissue concentration of the drug, biological half-life as well.","PeriodicalId":121861,"journal":{"name":"ChemRN: Medicinal Chemistry (Topic)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132905866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In-vitro Antimalarial and Antileishmanial Studies of Markhamia platycalyx Sprague Leaves 杨梅叶体外抗疟和抗利什曼原虫的研究
ChemRN: Medicinal Chemistry (Topic) Pub Date : 1900-01-01 DOI: 10.36876/smjmps.1002
Basma K. Mahmoud, A. Hamed, Mamdouh N. Samy, Amira Samir Wanas, Mohamed M Radwan, Mahmoud A Elsohly, Mohamed S. Kamel
{"title":"In-vitro Antimalarial and Antileishmanial Studies of Markhamia platycalyx Sprague Leaves","authors":"Basma K. Mahmoud, A. Hamed, Mamdouh N. Samy, Amira Samir Wanas, Mohamed M Radwan, Mahmoud A Elsohly, Mohamed S. Kamel","doi":"10.36876/smjmps.1002","DOIUrl":"https://doi.org/10.36876/smjmps.1002","url":null,"abstract":"Bignoniaceae is rich in active metabolites and includes numerous genera of high economic and therapeutic values. One of these plants is Markhamia platycalyx. The petroleum ether fraction of the total ethanol leaf extract of M. platycalyx exhibited IC50 26760 ng/mL against Plasmodium falciparum D6 and 22430 ng/mL against P. falciparum W2 in the 2nd phase assay. It did not show any cytotoxic activity against the VERO mammalian cells, indicating the safety of the petroleum ether fraction. Additionally, the dichloromethane fraction of the same extract was the most active fraction against Leishmania donovani amastigotes in THP1 with 86% inhibition in the 1ry phase assay, which was higher than Amphotericin B.","PeriodicalId":121861,"journal":{"name":"ChemRN: Medicinal Chemistry (Topic)","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124576129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书