{"title":"Introductory Chapter: The Important Physiological Characteristics and Industrial Applications of Acidophiles","authors":"Linxu Chen, Jian-qun Lin, Jianqiang Lin","doi":"10.5772/intechopen.101027","DOIUrl":"https://doi.org/10.5772/intechopen.101027","url":null,"abstract":"<jats:p />","PeriodicalId":121856,"journal":{"name":"Acidophiles - Fundamentals and Applications [Working Title]","volume":"152 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117339650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xue-Yan Gao, Jianqiang Lin, Linxu Chen, Jian-qiang Lin, Xin Pang
{"title":"Quorum Sensing of Acidophiles: A Communication System in Microorganisms","authors":"Xue-Yan Gao, Jianqiang Lin, Linxu Chen, Jian-qiang Lin, Xin Pang","doi":"10.5772/intechopen.100572","DOIUrl":"https://doi.org/10.5772/intechopen.100572","url":null,"abstract":"Communication is important for organisms living in nature. Quorum sensing system (QS) are intercellular communication systems that promote the sociality of microbes. Microorganisms could promote cell-to-cell cooperation and population density to adapt to the changing environment through QS-mediated regulation that is dependent on the secretion and the detection of signal molecules (or called autoinducers). QS system is also discovered in acidophiles, a microorganism that is widely used in the bioleaching industry and can live in an acidic environment. An example is the LuxI/R-like QS system (AfeI/R) that has been reported in the chemoautotrophic species of the genus Acidithiobacillus. In this chapter, we will introduce the types and distribution of the QS system, and the biological function and regulatory mechanism of QS in acidophiles. We will also discuss the potential ecological function of QS system and the application value of the QS system in the control and regulation of the bioleaching process in the related industries and acid mine damage.","PeriodicalId":121856,"journal":{"name":"Acidophiles - Fundamentals and Applications [Working Title]","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123802312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acidithiobacillus Its Application in Biomining Using a Quorum Sensing Modulation Approach","authors":"J. Caicedo, Sonia Villamizar","doi":"10.5772/intechopen.98774","DOIUrl":"https://doi.org/10.5772/intechopen.98774","url":null,"abstract":"A group of particular acidophiles microorganisms (bacteria and archaea) known as chemolithoautotrophs are capable of using minerals as fuel. Its oxidation generates electrons to obtain energy and carbon that is obtained by fixing CO2 from the air. During this aerobic mineral oxidation, metals are solubilized or biodegraded. Metal bioleaching usually is used in biomining and urban biomining approaches to recovery metals such as copper, gold and zinc. Several species of bacterial genus Acidithiobacillus display a great bioleaching activity. Bacterial attachment and biofilm formation are the initial requirements to begin a successful bioleaching process. Biofilm formation in Acidithiobacillus bacteria is strongly regulated by cell to cell communication system called Quorum Sensing. The goal of this chapter is to review the Quorum Sensing system mediated by the autoinducer N-acyl- homoserine-lactones in the Bacterium Acidiothiobacillus ferroxidans, in order to enhance and to boost the bioleaching technologies based in the use of this bacterium. The main applications of the cell-to-cell communication system concepts in A. ferrooxidans are reviewed in this chapter. It is that the addition of synthetic autoinducers molecules, which act as agonist of quorum sensing system, especially those with long acyl chains, both as single molecules (C12-AHL, 3-hydroxy-C12-AHL, C14-AHL, and 3-hydroxy-C14-AHL) or as a mixture (C14-AHL/3- hydroxy-C14-AHL/3-oxo-C14-AHL) increased the adhesion to sulfur and pyrite and enhance the metal bioleaching in urban biomining approaches.","PeriodicalId":121856,"journal":{"name":"Acidophiles - Fundamentals and Applications [Working Title]","volume":"203 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116180362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Thriving at Low pH: Adaptation Mechanisms of Acidophiles","authors":"Xian-ke Chen","doi":"10.5772/INTECHOPEN.96620","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96620","url":null,"abstract":"Acid resistance of acidophiles is the result of long-term co-evolution and natural selection of acidophiles and their natural habitats, and formed a relatively optimal acid-resistance network in acidophiles. The acid tolerance network of acidophiles could be classified into active and passive mechanisms. The active mechanisms mainly include the proton efflux and consumption systems, generation of reversed transmembrane electrical potential, and adjustment of cell membrane composition; the passive mechanisms mainly include the DNA and protein repair systems, chemotaxis and cell motility, and quorum sensing system. The maintenance of pH homeostasis is a cell-wide physiological process that adopt differently adjustment strategies, deployment modules, and integration network depending on the cell’s own potential and its habitat environments. However, acidophiles exhibit obvious strategies and modules similarities on acid resistance because of the long-term evolution. Therefore, a comprehensive understanding of acid tolerance network of acidophiles would be helpful for the intelligent manufacturing and industrial application of acidophiles.","PeriodicalId":121856,"journal":{"name":"Acidophiles - Fundamentals and Applications [Working Title]","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126955302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunomodulatory Potential of Lactobacillus acidophilus: Implications in Bone Health","authors":"A. Bhardwaj, L. Sapra, B. Verma, R. Srivastava","doi":"10.5772/INTECHOPEN.97063","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.97063","url":null,"abstract":"Lactobacillus acidophilus is homofermentative anaerobic rod-shaped gram-positive bacteria. L. acidophilous is one of the most common probiotics and is used for the treatment of various gastrointestinal, metabolic and inflammatory disorders. L. acidophilous produces antimicrobial compounds, maintains gut permeability and prevents dysbiosis. L. acidophilus also shows various other properties such as: it is anticarcinogenic, lowers serum cholesterol level and improves lactase metabolism of host. One of the most significant property of L. acidophilous is that it modulates the immune system and can prevent various inflammatory disorders. L. acidophilous influences several immune cells such as Th17 cells and Tregs. Various studies reported that inflammation induces bone loss and leads to several bone pathologies such as osteoporosis, rheumatoid arthritis and periodontitis. Recent studies have shown the potential of probiotics in preventing inflammation mediated bone loss. L. acidophilous is one of these probiotics and is found capable in inhibition of various bone disorders. L. acidophilous restores the dysregulated immune homeostasis and prevents inflammatory bone loss. Thus, L. acidophilous can be a potential therapeutic for the management of various bone pathologies. In this book chapter we reviewed various immunomodulatory properties of L. acidophilous along with its efficacy in preventing dysbiosis and maintaining gut permeability. We also discussed the potential role of L. acidophilous as a therapeutic for the management of inflammation induced bone disorders.","PeriodicalId":121856,"journal":{"name":"Acidophiles - Fundamentals and Applications [Working Title]","volume":"330 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116123769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}