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Eye Infections - Recent Advances in Diagnosis and Treatment [Working Title]最新文献

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Acute Postoperative Infectious Endophthalmitis: Advances in Diagnosis and Treatment 急性术后感染性眼内炎的诊断与治疗进展
Eye Infections - Recent Advances in Diagnosis and Treatment [Working Title] Pub Date : 2021-05-17 DOI: 10.5772/INTECHOPEN.97545
S. Mota, J. Guerrero-Naranjo, J. Dalma-Weiszhausz, R. Vélez-Montoya, J. Gonzalez-Cortes
{"title":"Acute Postoperative Infectious Endophthalmitis: Advances in Diagnosis and Treatment","authors":"S. Mota, J. Guerrero-Naranjo, J. Dalma-Weiszhausz, R. Vélez-Montoya, J. Gonzalez-Cortes","doi":"10.5772/INTECHOPEN.97545","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.97545","url":null,"abstract":"Acute postoperative infectious endophthalmitis remains one of the most dreaded complications of ophthalmic surgery. One of the keys to success in treating this complication is to make an early clinical diagnosis and, if possible, an etiologic diagnosis that can guide treatment with antibiotic therapy. Different antibiotic therapy modalities have emerged over the years that have made it possible to treat even resistant strains of various microorganisms that cause endophthalmitis. Another relevant advance made in the etiological diagnosis of endophthalmitis is the advent of molecular biology techniques, such as the real-time polymerase chain reaction, which can detect minimal amounts of the genetic material of the causative microorganism present in the vitreous in a short period of time, thus improving treatment outcomes with better-guided therapy with intravitreal antibiotics. Aside from advances in postoperative diagnosis methods, the surgical treatment of endophthalmitis has had significant improvements in vitrectomy techniques, and in many cases, it has been proposed as the first-line treatment concomitantly with intravitreal antibiotic therapy. Moreover, there is increasing evidence that prophylaxis with intracameral antibiotic therapy further decreases postoperative endophthalmitis incidence.","PeriodicalId":113249,"journal":{"name":"Eye Infections - Recent Advances in Diagnosis and Treatment [Working Title]","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125066637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Potency of SARS-CoV-2 on Ocular Tissues SARS-CoV-2对眼部组织的效力
Eye Infections - Recent Advances in Diagnosis and Treatment [Working Title] Pub Date : 2021-04-08 DOI: 10.5772/INTECHOPEN.97055
Saliha Durak, Hande Eda Sutova, Abuzer Alp Yetisgin, Ozlem Kutlu, Sibel Çetinel
{"title":"Potency of SARS-CoV-2 on Ocular Tissues","authors":"Saliha Durak, Hande Eda Sutova, Abuzer Alp Yetisgin, Ozlem Kutlu, Sibel Çetinel","doi":"10.5772/INTECHOPEN.97055","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.97055","url":null,"abstract":"The current COVID-19 pandemic has affected more than 100 million people and resulted in morbidity and mortality around the world. Even though the disease caused by SARS-CoV-2 is characterized by respiratory tract involvement, previous and recent data also indicates ocular manifestation. Not surprisingly, cell entry point of the virus, ACE2 receptor, is widely expressed in ocular tissues ranging from conjunctiva to retina. Despite the sensibility of ocular tissues, the sophisticated defense mechanism of the eye might eliminate viral transmission. Nevertheless, the potential of systemic transmission through the nasolacrimal duct may not be eliminated. In the case of ocular involvement, the disease outcomes might be as treatable as conjunctivitis or as serious as retinal degeneration and the treatment regimen vary accordingly. Within these contingencies, our aim with this chapter is to shed light on molecular bases of SARS-CoV-2 infection, systemic invasiveness following ocular transmission, manifestation and permanent effects on ocular tissues.","PeriodicalId":113249,"journal":{"name":"Eye Infections - Recent Advances in Diagnosis and Treatment [Working Title]","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134442698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endogenous Endophthalmitis: Etiology and Treatment 内源性眼内炎:病因与治疗
Eye Infections - Recent Advances in Diagnosis and Treatment [Working Title] Pub Date : 2021-03-31 DOI: 10.5772/INTECHOPEN.96766
S. Kabbara, N. Kelkar, M. Conway, G. Peyman
{"title":"Endogenous Endophthalmitis: Etiology and Treatment","authors":"S. Kabbara, N. Kelkar, M. Conway, G. Peyman","doi":"10.5772/INTECHOPEN.96766","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96766","url":null,"abstract":"This chapter comprehensively covers all aspects of endogenous endophthalmitis from systemic infectious agents, with an emphasis on reported and newer etiologies to broaden the diagnostic and investigative acumen of treating ophthalmic providers. The discussion includes the etiology of metastatic endophthalmitis and diagnostic investigations, including polymerase chain reaction (PCR), for identification of bacterial and viral infections involving the eye in both immunosuppressed in non-immunosuppressed patients. Additionally, we present clinical and diagnostic findings of fungal infections, protozoal infections, and helminthic infections. Pediatric cases are also reported and etiologies described. We discuss both etiology and diagnostic challenges. Current therapeutic modalities and outcomes are reviewed. While no two cases of metastatic endophthalmitis are the same, some similarities may exist that allow us to generalize how to approach and treat this potentially sight- and life-threatening spectrum of diseases and find the underlying systemic cause.","PeriodicalId":113249,"journal":{"name":"Eye Infections - Recent Advances in Diagnosis and Treatment [Working Title]","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129737668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Ocular Toxoplasmosis: An Update on Diagnosis, Multimodal Imaging and Therapy 眼弓形虫病:诊断、多模态成像和治疗的最新进展
Eye Infections - Recent Advances in Diagnosis and Treatment [Working Title] Pub Date : 2021-03-26 DOI: 10.5772/INTECHOPEN.96752
Terese K. Gerges
{"title":"Ocular Toxoplasmosis: An Update on Diagnosis, Multimodal Imaging and Therapy","authors":"Terese K. Gerges","doi":"10.5772/INTECHOPEN.96752","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96752","url":null,"abstract":"Ocular toxoplasmosis remains to be the most common cause of infectious uveitis in immunocompetent individuals with highly variable prognosis. The transmission mode can be either congenital or acquired. A precise diagnosis of the disease is necessary to opt effective and rapid treatment. While ocular toxoplasmosis usually presents in the classic form, it may as well present in variable clinical spectrum. The diagnosis can be suspected by the ocular inflammatory clinical presentation as well as multimodal imaging. However, serologic tests including intraocular fluid testing may be needed. Treatment includes combination of systemic antiparasitic and anti-inflammatory drugs with variable effectivity. More recently, intravitreally antimicrobials may be used. The chapter aims to layout the different clinical presentations and complications of ocular toxoplasmosis. Diagnostic techniques and different antimicrobial combinations for treatment will also be discussed.","PeriodicalId":113249,"journal":{"name":"Eye Infections - Recent Advances in Diagnosis and Treatment [Working Title]","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126323594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Recent Advances in the Diagnosis and Management of Herpetic Keratitis 疱疹性角膜炎诊断与治疗的最新进展
Eye Infections - Recent Advances in Diagnosis and Treatment [Working Title] Pub Date : 2021-03-15 DOI: 10.5772/INTECHOPEN.96898
A. Nowinska
{"title":"Recent Advances in the Diagnosis and Management of Herpetic Keratitis","authors":"A. Nowinska","doi":"10.5772/INTECHOPEN.96898","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.96898","url":null,"abstract":"The chapter is focused on one of the major cause of keratitis - Herpetic keratitis, its epidemiology, natural course, clinical forms, prognosis, diagnosis and treatment. The estimated global incidence of HSV keratitis is roughly 1,5 million, including 40,000 new cases of each year. Patients are usually affected in the early decades of live, therefore the disease has a severe impact on quality of life and quality of vision in young, productive adults. The author describes the detailed corneal characteristics, provides slit lamp photographs, optical coherence tomography scans and confocal microscopy results of different forms of the HSV keratitis: epithelial, stromal, necrotizing and endothelial. The chapter also discusses recent methods of diagnosis based on PCR testing as well as established and future methods of treatment based on the latest research results.","PeriodicalId":113249,"journal":{"name":"Eye Infections - Recent Advances in Diagnosis and Treatment [Working Title]","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127657655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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