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B15. IMMUNOTHERAPY FOR LUNG DISEASE最新文献

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Benralizumab for Chronic Obstructive Pulmonary Disease: Results of the Phase III GALATHEA Trial Benralizumab治疗慢性阻塞性肺疾病:III期GALATHEA试验结果
B15. IMMUNOTHERAPY FOR LUNG DISEASE Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2626
G. Criner, B. Celli, C. Brightling, A. Agustí, A. Papi, F. Sciurba, D. Sin, C. Vogelmeier, M. Kato, V. Shih, M. Jison, P. Newbold, M. Goldman, U. Martin
{"title":"Benralizumab for Chronic Obstructive Pulmonary Disease: Results of the Phase III GALATHEA Trial","authors":"G. Criner, B. Celli, C. Brightling, A. Agustí, A. Papi, F. Sciurba, D. Sin, C. Vogelmeier, M. Kato, V. Shih, M. Jison, P. Newbold, M. Goldman, U. Martin","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2626","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2626","url":null,"abstract":"","PeriodicalId":104393,"journal":{"name":"B15. IMMUNOTHERAPY FOR LUNG DISEASE","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125349591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dupilumab Reduces Severe Exacerbations and Improves Lung Function Regardless of Baseline Bronchodilator Reversibility in Patients with Uncontrolled Moderate-to-Severe Asthma Enrolled in the LIBERTY ASTHMA QUEST Study 在LIBERTY Asthma QUEST研究中，Dupilumab可降低中重度哮喘患者的严重恶化并改善肺功能，无论基线支气管扩张剂可逆性如何
B15. IMMUNOTHERAPY FOR LUNG DISEASE Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2624
I. Pavord, M. Castro, K. Rabe, N. Hanania, A. Papi, J. Fitzgerald, M. Rice, P. Rowe, Y. Lu, N. Amin, H. Staudinger, N. Graham, A. Teper
{"title":"Dupilumab Reduces Severe Exacerbations and Improves Lung Function Regardless of Baseline Bronchodilator Reversibility in Patients with Uncontrolled Moderate-to-Severe Asthma Enrolled in the LIBERTY ASTHMA QUEST Study","authors":"I. Pavord, M. Castro, K. Rabe, N. Hanania, A. Papi, J. Fitzgerald, M. Rice, P. Rowe, Y. Lu, N. Amin, H. Staudinger, N. Graham, A. Teper","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2624","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2624","url":null,"abstract":"","PeriodicalId":104393,"journal":{"name":"B15. IMMUNOTHERAPY FOR LUNG DISEASE","volume":"349 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114075928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Dose-Ranging Study (TERRANOVA) of Benralizumab for Moderate to Severe Chronic Obstructive Pulmonary Disease Benralizumab治疗中重度慢性阻塞性肺疾病的剂量范围研究(TERRANOVA
B15. IMMUNOTHERAPY FOR LUNG DISEASE Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2625
B. Celli, G. Criner, D. Singh, M. Bafadhel, V. Backer, A. Ramírez-Venegas, Y.-F. Wei, L. Bjermer, V. Shih, S. O'Quinn, Natalya Makulova, P. Newbold, M. Goldman, U. Martin
{"title":"A Dose-Ranging Study (TERRANOVA) of Benralizumab for Moderate to Severe Chronic Obstructive Pulmonary Disease","authors":"B. Celli, G. Criner, D. Singh, M. Bafadhel, V. Backer, A. Ramírez-Venegas, Y.-F. Wei, L. Bjermer, V. Shih, S. O'Quinn, Natalya Makulova, P. Newbold, M. Goldman, U. Martin","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2625","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2625","url":null,"abstract":"","PeriodicalId":104393,"journal":{"name":"B15. IMMUNOTHERAPY FOR LUNG DISEASE","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129696453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preservation of Lung Function Observed in a Phase 3 Randomized Controlled Trial of Tocilizumab for the Treatment of Early Systemic Sclerosis 托珠单抗治疗早期系统性硬化症的3期随机对照试验中观察到肺功能的保存
B15. IMMUNOTHERAPY FOR LUNG DISEASE Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2627
D. Khanna, Celia J. F. Lin, J. Goldin, G. Kim, M. Kuwana, Y. Allanore, A. Batalov, I. Butrimienė, P. Carreira, M. Matucci-Cerinic, O. Distler, D. Kaliterna, C. Mihai, M. Mogensen, M. Olesińska, J. Pope, G. Riemekasten, T. Rodríguez-Reyna, M. Santos, J. Laar, H. Spotswood, J. Siegel, A. Jahreis, D. Furst, C. Denton
{"title":"Preservation of Lung Function Observed in a Phase 3 Randomized Controlled Trial of Tocilizumab for the Treatment of Early Systemic Sclerosis","authors":"D. Khanna, Celia J. F. Lin, J. Goldin, G. Kim, M. Kuwana, Y. Allanore, A. Batalov, I. Butrimienė, P. Carreira, M. Matucci-Cerinic, O. Distler, D. Kaliterna, C. Mihai, M. Mogensen, M. Olesińska, J. Pope, G. Riemekasten, T. Rodríguez-Reyna, M. Santos, J. Laar, H. Spotswood, J. Siegel, A. Jahreis, D. Furst, C. Denton","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2627","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2627","url":null,"abstract":"","PeriodicalId":104393,"journal":{"name":"B15. IMMUNOTHERAPY FOR LUNG DISEASE","volume":"47 18","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114100047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The Placebo Response on Lung Function in Recent Clinical Trials of Asthma Biologics 近期哮喘生物制剂临床试验中安慰剂对肺功能的影响
B15. IMMUNOTHERAPY FOR LUNG DISEASE Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2628
M. Chen, Marco Peters, B. Yoo, C. Holweg, C. Lew
{"title":"The Placebo Response on Lung Function in Recent Clinical Trials of Asthma Biologics","authors":"M. Chen, Marco Peters, B. Yoo, C. Holweg, C. Lew","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2628","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2628","url":null,"abstract":"","PeriodicalId":104393,"journal":{"name":"B15. IMMUNOTHERAPY FOR LUNG DISEASE","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133020689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Oral TORC1 Inhibitor Dactolisib Enhances Immune Function and Reduces the Incidence of Respiratory Tract Infections in Elderly Subjects with Asthma 口服TORC1抑制剂Dactolisib增强老年哮喘患者的免疫功能并降低呼吸道感染的发生率
B15. IMMUNOTHERAPY FOR LUNG DISEASE Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2623
J. Mannick, S. Shergill, G. Teo
{"title":"Oral TORC1 Inhibitor Dactolisib Enhances Immune Function and Reduces the Incidence of Respiratory Tract Infections in Elderly Subjects with Asthma","authors":"J. Mannick, S. Shergill, G. Teo","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2623","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2623","url":null,"abstract":"","PeriodicalId":104393,"journal":{"name":"B15. IMMUNOTHERAPY FOR LUNG DISEASE","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116293882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Tezepelumab on Hospitalization and Emergency Department Visits in Patients with Severe Uncontrolled Asthma: Results from the Pathway Phase 2b Trial Tezepelumab对严重未控制哮喘患者住院和急诊就诊的影响:来自Pathway 2b期试验的结果
B15. IMMUNOTHERAPY FOR LUNG DISEASE Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2622
J. Corren, Stephanie Chen, L. Callan, E. G. Gil
{"title":"The Impact of Tezepelumab on Hospitalization and Emergency Department Visits in Patients with Severe Uncontrolled Asthma: Results from the Pathway Phase 2b Trial","authors":"J. Corren, Stephanie Chen, L. Callan, E. G. Gil","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2622","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2622","url":null,"abstract":"","PeriodicalId":104393,"journal":{"name":"B15. IMMUNOTHERAPY FOR LUNG DISEASE","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127328978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Tezepelumab Treatment Effect on Annualized Rate of Exacerbations by Baseline Biomarkers in Uncontrolled Severe Asthma Patients: Phase 2b PATHWAY Study Tezepelumab治疗对未控制的严重哮喘患者基线生物标志物年化加重率的影响:2b期途径研究
B15. IMMUNOTHERAPY FOR LUNG DISEASE Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2621
J. Corren, E. G. Gil, J. Parnes, Tuyet-Hang Pham, J. Griffiths
{"title":"Tezepelumab Treatment Effect on Annualized Rate of Exacerbations by Baseline Biomarkers in Uncontrolled Severe Asthma Patients: Phase 2b PATHWAY Study","authors":"J. Corren, E. G. Gil, J. Parnes, Tuyet-Hang Pham, J. Griffiths","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2621","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2621","url":null,"abstract":"","PeriodicalId":104393,"journal":{"name":"B15. IMMUNOTHERAPY FOR LUNG DISEASE","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128714140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
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