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Global Journal of Fertility and Research最新文献

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Higher levels of Hepatocyte Growth Factor (HGF) in human seminal plasma in comparison with blood plasma and negative association with several motile sperm cells 与血浆相比，人精浆中肝细胞生长因子(HGF)水平较高，与几种活动精子呈负相关
Global Journal of Fertility and Research Pub Date : 2023-07-19 DOI: 10.17352/gjfr.000023
Larsson Anders, Carlsson Lena, Khierallah Rasha, Holte Jan, Kallak Theodora Kunovac
{"title":"Higher levels of Hepatocyte Growth Factor (HGF) in human seminal plasma in comparison with blood plasma and negative association with several motile sperm cells","authors":"Larsson Anders, Carlsson Lena, Khierallah Rasha, Holte Jan, Kallak Theodora Kunovac","doi":"10.17352/gjfr.000023","DOIUrl":"https://doi.org/10.17352/gjfr.000023","url":null,"abstract":"Context: Semen is a complex fluid with many functions, some of them well-known, others more obscure. Aims: The aim of this study was to investigate the levels of Hepatocyte Growth Factor (HGF) in human seminal plasma in comparison with blood plasma levels. Methods: HGF concentrations were measured in seminal plasma from 40 men utilizing commercial ELISA kits. Blood plasma from 40 healthy blood donors served as a comparison group. Results: Median seminal plasma HGF was approximately five times higher than the levels found in blood plasma (5717.5 pg/mL vs. 1124.6 pg/mL). There was a negative correlation between HGF values in seminal plasma and the number of sperm cells. Conclusion: The study shows that seminal plasma contains high levels of HGF and that HGF binds to prostasomes. Male HGF can thus reach the female reproductive tract during unprotected sexual intercourse. Further studies are warranted to evaluate the effect of this on fertility.","PeriodicalId":104315,"journal":{"name":"Global Journal of Fertility and Research","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123454826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of prepubertal to peripubertal exposure of triclosan on the reproductive health of the young male laboratory mice 青春期前和青春期周围接触三氯生对年轻雄性实验小鼠生殖健康的影响
Global Journal of Fertility and Research Pub Date : 2023-06-26 DOI: 10.17352/gjfr.000022
R. Shobha, S. Poonam
{"title":"Effects of prepubertal to peripubertal exposure of triclosan on the reproductive health of the young male laboratory mice","authors":"R. Shobha, S. Poonam","doi":"10.17352/gjfr.000022","DOIUrl":"https://doi.org/10.17352/gjfr.000022","url":null,"abstract":"Over the last few decades, a massive increase in environmental toxicants has played a significant role in causing hindrance in the process of sexual maturity, leading to impaired reproductive health. Several toxicants are existing in the environment because of rapid industrialization, agricultural activities, and urbanization that act as endocrine disrupting chemicals (EDCs). Triclosan (TCS; 2,4,4’-trichloro-2’-hydroxydiphenyl ether) is one of the EDCs, acts as an antimicrobial chemical, and is used widely in personal care products and several commercial preparations as preservatives. It is found to interfere with normal reproduction and sexual maturity. The present study is therefore, aimed to investigate the impact of prepubertal to peripubertal exposure of TCS (300 and 600 mg/kg BW/day from PND 22 to PND 63) to observe the age of the onset of puberty, weights of the reproductive organs, alterations in the levels of testicular cholesterol, serum testosterone, and histopathology of the testis in the young laboratory mice. TCS exposure caused a significant delay in the age of prepuce separation, an indicator of the onset of puberty. Its exposure from PND 22 to PND 63 resulted in significant reductions in the weights of the testis, epididymis, and seminal vesicle, levels of testicular cholesterol, and serum testosterone in the young mice at PND 64. Testicular histology of such mice also showed regressive changes in the seminiferous tubules, indicating the interference of TCS in the process of spermatogenesis. The findings of the present study, therefore, reveal that TCS delays the age of onset of puberty and interferes with the endocrine functions of the testis.","PeriodicalId":104315,"journal":{"name":"Global Journal of Fertility and Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130035161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Description of the characteristics influencing the therapeutic managment of infertile couples in western Algeria 阿尔及利亚西部影响不孕夫妇治疗管理的特点描述
Global Journal of Fertility and Research Pub Date : 2020-12-16 DOI: 10.17352/gjfr.000017
N. Belhachemi, Zelmat Sa, B. Chafi, M. Foughal, W MohandArabe
{"title":"Description of the characteristics influencing the therapeutic managment of infertile couples in western Algeria","authors":"N. Belhachemi, Zelmat Sa, B. Chafi, M. Foughal, W MohandArabe","doi":"10.17352/gjfr.000017","DOIUrl":"https://doi.org/10.17352/gjfr.000017","url":null,"abstract":"The aim of this work is to describe and identify the characteristics that can influence the care of these infertile couples.","PeriodicalId":104315,"journal":{"name":"Global Journal of Fertility and Research","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116394220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Sperm immobilization factor of Candida albicans: A proposed mechanism of infertility in female mice 白色念珠菌的精子固定因子:雌性小鼠不孕的一种机制
Global Journal of Fertility and Research Pub Date : 2020-02-27 DOI: 10.17352/gjfr.000014
Sareeka Kumari, Aditi Chauhan, Deepali Thaper, V. Prabha
{"title":"Sperm immobilization factor of Candida albicans: A proposed mechanism of infertility in female mice","authors":"Sareeka Kumari, Aditi Chauhan, Deepali Thaper, V. Prabha","doi":"10.17352/gjfr.000014","DOIUrl":"https://doi.org/10.17352/gjfr.000014","url":null,"abstract":"Candida species are the most frequently isolated fungi, responsible for blood stream and urinary tract infections. Various studies have shown Candida albicans to be associated with impediment of sperm parameters. Therefore to determine the underlying mechanism, the standard strain of Candida albicans (MTCC 1637) was employed and it was found to cause complete immobilization of mouse spermatozoa in vitro. Further, sperm immobilization activity was shown by only cell-free supernatant, indicating that the sperm immobilization factor might be released extracellularly, as no activity was observed with the washed cells. The sperm immobilization factor (SIF) from supernatant was precipitated out with ammonium sulphate at the saturation of 60% to 80% and was purified by gel permeation chromatography followed by ion exchange chromatography.","PeriodicalId":104315,"journal":{"name":"Global Journal of Fertility and Research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116949666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Prediction of Premature Ovarian Insuffi ciency and prevalence of medical diseases 卵巢功能不全与医学疾病患病率的预测
Global Journal of Fertility and Research Pub Date : 2019-09-16 DOI: 10.17352/gjfr.000013
H. El-Jabu, I. Elfortia, A. Andisha, B. Gerriw, H. Ben-Saleh, R. Abukail, H. Mlitan, E. El-Gomati, E. Elmahjoob
{"title":"Prediction of Premature Ovarian Insuffi ciency and prevalence of medical diseases","authors":"H. El-Jabu, I. Elfortia, A. Andisha, B. Gerriw, H. Ben-Saleh, R. Abukail, H. Mlitan, E. El-Gomati, E. Elmahjoob","doi":"10.17352/gjfr.000013","DOIUrl":"https://doi.org/10.17352/gjfr.000013","url":null,"abstract":"POF can be considered as an end stage of multiple disorders that ends by loss of ovarian function [1]. However, there are other terms that include POI, when the condition is different because there may be intermittent and unpredictable resumption of the ovarian activity [2].","PeriodicalId":104315,"journal":{"name":"Global Journal of Fertility and Research","volume":"280 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116556149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Impact of Oxidative stress on Infertility, with emphasis on infertility management strategies 氧化应激对不孕症的影响，重点是不孕症的管理策略
Global Journal of Fertility and Research Pub Date : 2019-08-02 DOI: 10.17352/GJFR.000012
P. Banerjee, J. Bhattacharya
{"title":"Impact of Oxidative stress on Infertility, with emphasis on infertility management strategies","authors":"P. Banerjee, J. Bhattacharya","doi":"10.17352/GJFR.000012","DOIUrl":"https://doi.org/10.17352/GJFR.000012","url":null,"abstract":"Oxidative stress (OS) is a state of imbalance between pro-oxidants (Reactive Oxygen species and Reactive Nitrogen species) and antioxidant defences.","PeriodicalId":104315,"journal":{"name":"Global Journal of Fertility and Research","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129983775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Statistical analysis of early marriage among women in Ethiopia by using multilevel logistic regression 埃塞俄比亚妇女早婚的多水平logistic回归统计分析
Global Journal of Fertility and Research Pub Date : 2019-04-16 DOI: 10.17352/GJFR.000011
T. A. Gashaw
{"title":"Statistical analysis of early marriage among women in Ethiopia by using multilevel logistic regression","authors":"T. A. Gashaw","doi":"10.17352/GJFR.000011","DOIUrl":"https://doi.org/10.17352/GJFR.000011","url":null,"abstract":"Early marriage is still widely practiced in many parts of the world mainly in Latin America, the Caribbean, Southern Asia and countries of Africa. Ethiopia has one of the highest rates of early marriage in Sub-Saharan Africa. The main objective of this study was to identify determinants of early marriage among women in Ethiopians and to examine variations in early marriage between and within regions of Ethiopia. The study is made based on the Ethiopian Demographic and Health Survey 2011 data that has two stages sampling hierarchical structure, collected for 9262 married women nested within eleven regions with age 15-49 years. Descriptive statistics and multilevel logistic regression model analysis were used to examine the prevalence and identify determinants of early marriage. The results of descriptive statistics shows that Out of the 9,262 married women, 3320(35.8%) of marriages occur 18 years and above while 5942 (64.2%) of these women married early (under 18 years) at the time of the survey.","PeriodicalId":104315,"journal":{"name":"Global Journal of Fertility and Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125829951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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