农林科学最新文献

{"title":"Evaluation of a 0.05 T low-field MRI system for canine brain imaging via comparison with images acquired at 1.5 T field strength: a pilot cadaver study.","authors":"Elisabeth Maria Burgers, Samantha Miles, Stefanie Veraa, Thomas O'Reilly, Ruben van den Broek, Chloé Najac, Beatrice Lena, Andrew Webb","doi":"10.1080/01652176.2026.2720640","DOIUrl":"10.1080/01652176.2026.2720640","url":null,"abstract":"<p><p>Magnetic resonance imaging (MRI) systems continue to grow in number in veterinary and human medicine with higher field strength magnets increasingly available; however, the associated high costs have created healthcare inequities. This technical feasibility study aimed to evaluate a low-cost, portable, and permanent magnet-based 0.05 T low-field system (LF), originally designed for human neuroimaging, for assessing the canine brain. By using 23 canine cadavers, a scanning protocol was developed, consisting of transverse T1-weighted (T1w) and T2-weighted (T2w) sequences, and compared to a 1.5 T (HF) protocol for the visibility of 22 anatomical features. For the purpose of hydrocephalus evaluation, the LF system showed non-inferior detection of the lateral ventricles (LV) and mesencephalic aqueduct on T2w sequences with >90% conditional probability for detecting these features on the LF, given they were present on the HF. For T1w sequences, the LF system had inconclusive non-inferiority for detection of LV with 76.6% conditional probability. In summary, a canine brain scanning protocol was successfully developed for a 0.05 T MRI with preliminary evaluation suggestive that this device can aid with the detection of hydrocephalus. Future <i>in vivo</i> studies are required to evaluate the device's true clinical application.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2720640"},"PeriodicalIF":3.9,"publicationDate":"2026-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13573525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148957272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Untangling animal-based production narratives: a review of UK's post-Brexit policy landscape.","authors":"Amber Lawes-Johnson, Mehroosh Tak, Siobhan M Abeyesinghe","doi":"10.1108/BFJ-04-2025-0405","DOIUrl":"10.1108/BFJ-04-2025-0405","url":null,"abstract":"<p><strong>Purpose: </strong>The article aimed to elucidate the United Kingdom government's proposed direction for the \"Public Money for Public Goods\" approach and future implications for livestock systems post-Brexit by identifying the overall coherence between post-Brexit livestock policies.</p><p><strong>Design/methodology/approach: </strong>A systematic policy review of post-Brexit livestock policies on gov.uk was undertaken. Of 505 policy documents initially identified, 44 were included in the final review after removing duplicates and applying exclusion criteria. A policy document analysis was conducted to iteratively build an <i>a priori</i> list of thematic categories discussing livestock and post-Brexit changes. Policy Narratives were produced, supporting these data with grey and academic literature.</p><p><strong>Findings: </strong>UK livestock policy overlooks the diverse needs of different farming systems. Public goods definitions related to livestock systems remain ill-defined. Policies often conflict and lack ambition for a comprehensive public goods transition.</p><p><strong>Research limitations/implications: </strong>The rapid pace at which government policy evolves imposed difficulty in reviewing new or updated policies. Also, policy terminology varied between documents, including an inherent vagueness of language. Both factors required substantial interpretation, potentially introducing bias.</p><p><strong>Practical implications: </strong>Failure to address the gaps identified across policies will lead to uneven social, economic and environmental outcomes for the animal-based farming sectors.</p><p><strong>Originality/value: </strong>Agricultural policy design needs to incorporate a critical food systems approach to ensure post-Brexit livestock policies and the public goods transition support different scales and types of farming businesses.</p>","PeriodicalId":9231,"journal":{"name":"British Food Journal","volume":"128 13","pages":"390-412"},"PeriodicalIF":4.4,"publicationDate":"2026-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7619235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148454750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"经济学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perfect diagnostic agreement between canine- and feline-specific parvovirus PoC antigen kits in feline panleukopenia.","authors":"Mahmoud S Safwat, Manar M Farouk, Ahmad Zaki Anwer, M E Ali, Nehal M Shahen, Dina A Abdelwahed, Rabab T Hassanien, Ahmed F Afify, M H Ali, Samah Eid, Othman N O Mansour, Mary A N Sargious, Mohamed I Abdallah, Reham Karam, Samah El-Sayed M","doi":"10.1080/01652176.2025.2604234","DOIUrl":"10.1080/01652176.2025.2604234","url":null,"abstract":"<p><p>Timely diagnosis is essential for managing feline panleukopenia (FPL), a devastating disease of cats caused by feline parvovirus (FPV) or canine parvovirus variants (CPV-2a, -2b, -2c). To support swift clinical decisions, point-of-care (PoC) antigen kits offer frontline tools. Given their cost and availability advantages, CPV-specific kits are often used off-label in cats; however, their interchangeability with manufacturer-matched FPV-specific kits remains unverified. This study assessed the diagnostic agreement between paired canine- and feline-specific PoC parvovirus antigen tests from two manufacturers. Fifty cats (30 with acute gastroenteritis, 20 healthy) were tested using all test formats. All cats underwent PCR and sequencing for parvovirus typing. Tests from the same manufacturer showed near-perfect or perfect agreement for result interpretation (Cohen's κ: 0.919 and 1.000). This strong inter-kit concordance also extended to test line intensity (<i>κ</i> = 0.908 and 1.000). Antigen-positive results were limited to diseased cats, mirroring the distribution of PCR positives. The latter included all the 30 cases, and were typed by sequencing as follows: 28 FPV, 1 CPV-2a, and 1 CPV-2c. All kit types detected FPV and CPV variants, and agreement within each manufacturer's paired kits was consistent across detected viral types. This preliminary evidence suggests that for two manufacturers, CPV antigen tests were non-inferior to their FPV counterparts, supporting flexible, cost-effective FPL diagnosis in cats, regardless of implicated parvovirus types.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2604234"},"PeriodicalIF":5.2,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12724100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145806303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CMLPS-N1: a novel preclinical cell line model for canine mammary tumor and its application in therapeutic screening.","authors":"Xiao Wang, Han Zhou, Qian Zhang, Yihan Liu, Lixin He, Wenxuan Li, Bin Ma, Lihong Luo, Lijun Guo, Changwei Qiu","doi":"10.1080/01652176.2026.2614697","DOIUrl":"10.1080/01652176.2026.2614697","url":null,"abstract":"<p><p>Canine mammary tumor is the most common tumor in intact female dogs and poses a growing health burden due to its high malignancy rate and increasing canine populations. However, research on sarcomatous subtypes has been hindered by a lack of representative cell lines. Here, we successfully established a novel canine mammary liposarcoma cell line, designated CMLPS-N1, which represents the first such model derived from a spontaneous tumor. This cell line has been stably maintained for over 80 passages and exhibits an abnormal karyotype, high proliferative and migratory capacity, and strong tumorigenicity in mouse xenografts. Molecular profiling confirmed a phenotype consistent with liposarcoma (MDM2+) and mesenchymal origin (Vimentin+/N-cadherin+), alongside high-risk markers (p53+/Ki67+/Notch1), and hormone receptor expression (ER/PR), while being negative for epithelial (PCK) and HER-2 markers. We used functional assays, including cell proliferation, colony formation, wound healing, and transwell invasion, to confirm its aggressive phenotype. Furthermore, cytotoxicity testing with four chemotherapy agents further supports its utility as a preclinical model for therapeutic screening and mechanistic research. The establishment of CMLPS-N1 enriches the canine mammary tumor cell line repository and provides a valuable experimental model for studying disease mechanisms, developing therapies, and facilitating translational applications.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2614697"},"PeriodicalIF":3.9,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12794710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145949414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning-assisted screening for canine Cushing's syndrome.","authors":"Young-Jae Yoo, Kyungchang Jeong, Hanbit Seo, Ha-Suk Nam, Yeon Chae, Taesik Yun, Byung-Teck Kang, Euijong Lee, Hakhyun Kim","doi":"10.1080/01652176.2025.2604643","DOIUrl":"10.1080/01652176.2025.2604643","url":null,"abstract":"<p><p>Cushing's syndrome (CS) is a common endocrine disorder in dogs that can significantly impair their quality of life. Diagnosis is often challenging because of its variable clinical presentation, making it difficult to identify suitable candidates for further diagnostic tests. This study employed machine learning algorithms to assist in CS diagnosis using routinely available screening diagnostics, including complete blood count, serum chemistry panel, and urinalysis parameters such as urine specific gravity and urine protein-to-creatinine ratio. Data were collected from 153 control dogs initially suspected of CS but later excluded and 152 dogs with confirmed CS. A boosted tree algorithm (gradient boosting) was trained on 80% of the collected data, with the remaining 20% reserved for testing. The developed model demonstrated an accuracy of 88.5% [95% confidence interval (CI): 80.5-96.5%], a sensitivity of 83.3% (95% CI: 70.7-96.7%), a specificity of 93.5% (95% CI: 84.9-100%), and an area under the receiver operating characteristic curve of 0.912 (95% CI: 0.835-0.988), indicating excellent discriminatory ability. A user-friendly graphical interface was also developed to facilitate clinical implementation, potentially improving diagnostic efficiency and owner satisfaction.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2604643"},"PeriodicalIF":5.2,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12777882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A bivalent subunit bovine herpesvirus 1 vaccine based on the ectodomains of glycoproteins D and B elicits robust protective immunity against infection in a rabbit model.","authors":"Wenxiao Liu, Chun Yang, Jijing Tian, Jing Cheng, Linyi Zhou, Munir Iqbal, Arslan Mehboob, Rebecca Daines, Sui Zhang, Mengjiao Chen, Xiaoying Wang, Yongqing Li","doi":"10.1080/01652176.2025.2607414","DOIUrl":"10.1080/01652176.2025.2607414","url":null,"abstract":"<p><p>Bovine alphaherpesvirus 1 (BoHV-1) is the causative agent of infectious bovine rhinotracheitis and reproductive disorders causing significant economic losses in the cattle industry. Both BoHV-1 glycoproteins B (gB) and D (gD) are targets of neutralizing antibodies and desirable antigens for subunit vaccine. In this study, a bivalent subunit vaccine was generated based on the ectodomain of gD and gB expressed by baculoviruses system. Compared with the inactivated vaccine, the bivalent subunit vaccine induced higher neutralizing antibody levels against both the BoHV-1 reference strain and the virulent BoHV-1 field strain. Following intranasally challenge with BoHV-1 J2303, the clinical signs and virus excretion were significantly reduced in rabbits vaccinated with this subunit vaccine whereas severe clinical symptoms appeared in the non-vaccinated rabbits, indicating that the bivalent subunit vaccine provides complete protection against virulent BoHV-1 infection. Considering that the respiratory symptoms caused by J2303 in rabbits is highly similar and even identical to those of cattle, our findings suggest that the bivalent subunit vaccine based on combination of gD with gB protein have promising application to BoHV-1control programs.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2607414"},"PeriodicalIF":5.2,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12777838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Animal biosecurity framework development, implementation and evaluation in a veterinary education establishment.","authors":"Claude Saegerman, Constance Wielick, Véronique Renault, Priscilla Burnotte, Christine Grignet, Laurent Leinartz, Maxime Harmegnies, Sophie Tasnier, Christiaen Remy, Calixte Bayrou, Nicolas Ochelen, Tatiana Art, Pierre Lekeux, Jason W Stull, Marie-France Humblet","doi":"10.1080/01652176.2026.2626257","DOIUrl":"10.1080/01652176.2026.2626257","url":null,"abstract":"<p><p>Over the last decades, biosecurity has received increasing attention in veterinary medicine and was recently integrated as a competency for One Health field epidemiology framework by international bodies. It is also a standard in the European System of Evaluation of Veterinary Training and in the accreditation of veterinary colleges by the American Veterinary Medical Association Council on Education. To help veterinary students and staff acquire biosecurity skills within veterinary education establishments, we first develop animal biosecurity research, and we spread its results through four interconnected instruments: biosecurity standard operating policies and procedures, a dedicated biosecurity website, an annual biosecurity day, and the production of checklists to assess the biosecurity level of compliance. The use of biosecurity standard operating procedures, the number of visits on the faculty biosecurity website, the number of people trained, and regular biosecurity audits performed are all factors that have contributed to the animal biosecurity to comply with the requirements of the European Association of Establishments for Veterinary Education and by the Council on Outcomes-based Veterinary Education, in the CBVE 2.0 book published by the American Association of Veterinary Medical Colleges. These approaches also contribute to the acquisition and maintenance of the accreditation delivered by the ad hoc bodies. The participation of students in the process allows a better comprehension and appropriation of animal biosecurity.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2626257"},"PeriodicalIF":3.9,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12879496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146119792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbiota-bile acid-host axis dysregulation drives enteropathogenesis in <i>Escherichia coli</i> K99-induced neonatal calf diarrhea.","authors":"Haihui Gao, Xiaodong Kang, Zhijie Liu, Yuqiong Li, Libing Bai, Kangkang Guo, Meizhou Huang","doi":"10.1080/01652176.2026.2617460","DOIUrl":"10.1080/01652176.2026.2617460","url":null,"abstract":"<p><p>Neonatal calf diarrhea caused by <i>Escherichia coli</i> K99 remains a critical challenge in livestock health, yet its precise pathogenic mechanisms are poorly defined. In this study, we identify bile acid (BA) metabolic dysregulation as a key pathogenic mechanism in <i>E. coli</i> K99-induced diarrhea. Using a neonatal calf infection model integrated with multi-omics profiling (including 16S rRNA sequencing, untargeted metabolomics, and targeted bile acid metabolomics), we demonstrate that <i>E. coli</i> K99 infection leads to significant disruption of the gut microbiota, compromises intestinal barrier integrity, and causes region-specific alterations in BA receptor signaling pathways (including FXR, TGR5, RAR, and ABST). Targeted metabolomic analysis revealed the accumulation of toxic primary and secondary BAs, driven by microbial shifts favoring BA-transforming pathogens and depleting BA-sensitive commensals. This microbial dysbiosis-BA imbalance-receptor dysfunction axis provokes immune activation, metabolic disturbances, and epithelial damage. Our study is the first to establish a mechanistic link between <i>E. coli</i> K99 infection and intestinal dysfunction <i>via</i> a microbiota-bile acid-host signaling cascade. These findings uncover a previously unrecognized pathophysiological pathway in bacterial diarrhea and suggest that modulation of gut microbiota and bile acid metabolism represents a promising therapeutic strategy for managing enteric infections in veterinary and potentially human medicine.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2617460"},"PeriodicalIF":3.9,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12862847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146087925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fisetin alleviates lipopolysaccharide-induced mastitis by inhibiting ferroptosis and modulating the gut microbiota.","authors":"Chao Tong, Li Wang, Haojie Wen, Xinhui Yao, Jiang Tong, Ruya Zhang, Xiao Li, Yuqiang Xiang, Xuebing Wang","doi":"10.1080/01652176.2026.2642789","DOIUrl":"10.1080/01652176.2026.2642789","url":null,"abstract":"<p><p>Bovine mastitis poses an enormous challenge to the dairy industry. At present, dependence on antibiotic therapy has led to problems such as antibiotic-resistant bacteria and drug residues. Therefore, it is very important to seek alternative therapies for the treatment of bovine mastitis. Fisetin (FIS) with antioxidant and anti-inflammatory properties is found in various fruits and vegetables, although its regulatory role in mastitis treatment remains unclear. In the present study, we employed lipopolysaccharide (LPS)-induced cellular and animal mastitis models to investigate the regulatory effects of FIS on oxidative stress and ferroptosis pathways in mastitis treatment, utilizing techniques such as western blot, quantitative real-time PCR (qRT-PCR), immunofluorescence, hematoxylin-eosin (HE) staining, ROS, MDA, SOD, T-AOC, tissue total iron content analysis, mouse gut microbiota sequencing, and untargeted metabolomics. The results demonstrated that FIS modulates oxidative stress and ferroptosis pathways, leading to a reduction in intracellular and mouse mammary tissue inflammatory cytokines level. Furthermore, FIS treatment altered the gut microbiota structure and metabolites in LPS-induced mice, increasing short-chain fatty acid (SCFA) levels, which contributed to the restoration of the blood-milk barrier and alleviation of mastitis. This study could lead to novel therapeutic strategies for bovine mastitis based on traditional Chinese medicine.</p>","PeriodicalId":51207,"journal":{"name":"Veterinary Quarterly","volume":"46 1","pages":"2642789"},"PeriodicalIF":3.9,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13003875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147476132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Honey as a Functional Food: Evaluating Its Antimicrobial Properties and Bacterial Safety Concerns.","authors":"Kobra Shirani, Amirmohammad Mottaghi, Mohammad Shabani","doi":"10.1177/15353141251392181","DOIUrl":"10.1177/15353141251392181","url":null,"abstract":"<p><p>Honey is increasingly recognized as a functional food with intrinsic antimicrobial properties. Its complex chemical makeup, high sugar content, low water activity, acidic pH, hydrogen peroxide generation, and a spectrum of bioactive phytochemicals create a multifaceted defense against microbial growth, yet honey also harbors diverse microorganisms, including potential pathogens, underscoring the need for robust quality control and safety considerations across production, processing, and storage. This study synthesizes current evidence on the antimicrobial mechanisms of honey and evaluates bacterial safety concerns, with emphasis on probiotic potential and risks associated with pathogens such as <i>Clostridium botulinum</i>, to inform safe use and innovative functional food applications. A comprehensive review of existing literature and honey-specific data was conducted to collate chemical, microbiological, and safety-related parameters. Key antimicrobial mechanisms (osmotic pressure, acidic environment, hydrogen peroxide production, and bioactive compounds such as methylglyoxal in certain varieties) were mapped to their effects on diverse microbes. Safety considerations, contamination pathways, and regulatory frameworks were qualitatively assessed to identify critical control points. Honey's antimicrobial activity arises from synergistic interactions among sugars, pH, hydrogen peroxide, enzymes, and phytochemicals, yielding broad-spectrum inhibition. Beneficial lactic acid bacteria from honey and bees contribute probiotic potential, while the risk of contamination by pathogens necessitates stringent hygiene, processing controls, and adherence to quality standards. Processors can leverage nonthermal and thermal reduction methods to balance safety with the preservation of bioactive components. Honey remains a robust functional food with antimicrobial advantages and probiotic opportunities, provided that meticulous quality control and regulatory compliance are maintained to mitigate safety risks for vulnerable populations. Future work should optimize honey-based probiotic formulations and establish standardized safety protocols across the supply chain.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":"839-853"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145388305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}