环境科学与生态学最新文献

{"title":"Leguminous green mulching alters the microbial community structure and increases microbial diversity by improving nitrogen availability in subtropical orchard systems in China.","authors":"Na Wang, Le Li, Mengmeng Gou, Jianwen Hu, Huiling Chen, Wenfa Xiao, Changfu Liu","doi":"10.1016/j.scitotenv.2024.176891","DOIUrl":"10.1016/j.scitotenv.2024.176891","url":null,"abstract":"<p><p>Microorganisms, the major decomposers of plant residues, are crucial for soil nutrient cycling. Living grass mulching effectively alters microbial community structure and promotes nutrient cycling. However, its consistency with mulching ages and growth periods remains unclear. Therefore, this study aims to clarify the dynamic characteristics of microbial communities and enzyme activities across different mulching ages. In this study, high-throughput sequencing technology was used to investigate bacterial and fungal community evolution in three mulching treatments with Vicia villosa for 8 years (VV_8), 4 years (VV_4), and clean tillage in a citrus orchard. This study covered three growth periods (citrus-grass: spring sprouting to budding period [SSBP], fruit swelling to withering period [FSWP], and fruit maturity to seeding period [FMSP]). The results showed that VV_4 and VV_8 treatments increased bacterial and fungal alpha diversity as well as the activities of nitrogen (N), carbon (C), and phosphorus cycling enzymes. C-cycling enzyme activity was the primary key factor driving changes in microbial diversity across growth periods. Under leguminous green mulching, bacteria alpha diversity increased the most during FSWP, while fungi increased the most during FMSP. Additionally, the relative abundance of Ascomycota and Basidiomycota significantly increased during the FSWP and FMSP, reaching 63.65-73.80 % and 79.73-84.51 %, respectively. With increasing mulching ages, the structural stability and synergistic effects of microorganisms were correspondingly enhanced. Furthermore, available nutrients determined microbial community evolution, with N availability being a key factor influencing microbial diversity, especially fungal diversity. In conclusion, as mulching ages increase, improved nutrient availability gradually enhances microbial diversity, synergistic interactions, and nutrient cycling functions, with copiotrophic taxa occupying a key position in the microbial network. FSWP is a critical turning point for enhancing microbial activity and C-cycling function. This study offers theoretical support for developing microbial regulation strategies to improve soil quality in orchard management practices.</p>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"955 ","pages":"176891"},"PeriodicalIF":8.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of emerging pollutants mixtures on marine and brackish phytoplankton: diatom Phaeodactylum tricornutum and cyanobacterium Microcystis aeruginosa.","authors":"Lilianna Sharma, Błażej Kudłak, Joanna Stoń-Egiert, Grzegorz Siedlewicz, Ksenia Pazdro","doi":"10.1016/j.scitotenv.2024.177080","DOIUrl":"10.1016/j.scitotenv.2024.177080","url":null,"abstract":"<p><p>Pharmaceuticals and ionic liquids (ILs) are emerging as significant micropollutants with environmental presence and potential ecological impacts. The possible simultaneous occurrence of these two groups of pollutants in aquatic environments raises complex challenges due to their diverse chemical properties and potential for interactive effects. Given the documented widespread presence of pharmaceuticals and the emerging concerns about ILs, the study aims to evaluate the adverse effects of binary mixtures of imidazolium ionic liquid IM1-8C(CN)₃ and two representatives of pharmaceuticals: antibiotic oxytetracycline (OXTC) and metabolite carbamazepine 10,11 epoxide (CBZ-E) on the brackish cyanobacterium Microcystis aeruginosa and the marine diatom Phaeodactylum tricornutum during chronic exposure experiments. A comprehensive approach was employed, incorporating various endpoints including oxidative stress, chlorophyll a fluorescence, detailed photoprotective and photosynthetic pigment profiles of target microorganisms to assess modes of action and identify the mixture effects of the selected substances. The observed alterations in pigment production affecting carotenoids synthesis in both selected species may be attributed to the differential impacts of these substances on the photosynthetic pathways and metabolic processes in the cyanobacterial and diatom cells. Changes in chlorophyll a fluorescence-specific parameters suggest impairment of the photosynthetic activity, particularly affecting the efficiency of photosystem II. The application of Concentration Addition (CA) and Independent Action (IA) mathematical models, complemented by the evaluation of Model Deviation Ratios (MDR), revealed predominantly antagonistic interactions within the studied mixtures. The findings of this study provide important insights into the effects of mixtures of organic micropollutants and their potential impact on environment including brackish and marine waters.</p>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":" ","pages":"177080"},"PeriodicalIF":8.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A parallel compositional reservoir simulator for large-scale CO₂ geological storage modeling and assessment.","authors":"Chaojie Di, Yizheng Wei, Kun Wang, Benjieming Liu, Peng Deng, Zhe Sun, Xuantong Lei, Zhangxin Chen","doi":"10.1016/j.scitotenv.2024.177065","DOIUrl":"10.1016/j.scitotenv.2024.177065","url":null,"abstract":"<p><p>Storing CO₂ in deep aquifers and depleted gas reservoirs is an effective way to achieve carbon neutrality. However, the numerical simulation of CO₂ storage in these formations is challenging due to the complexity of gases-brine systems. The number of gas species included in the gases-brine fluid models of existing simulators cannot meet the rapidly evolving CO₂ sequestration scenarios. To address this intricate issue, we developed a three-dimensional fully implicit parallel CO₂ geological storage simulator (PRSI-CGCS) on distributed-memory computers based on our in-house parallel platform. This simulator uses a compositional fluid model with a diverse range of gas species, including CO₂, C₁ ~ C₃, N₂, H₂S, as well as newly added gases H₂ and O₂, which may be encountered in geological CO₂ storages. Besides, we provide more suitable scaling factors for different gases in the stability analysis bypassing (SAB) method to accelerate the gases-brine phase equilibrium calculations. PRSI-CGCS does not incorporate energy conservation equations, and salt precipitation or dissolution is also not considered. Numerical experiments show that our simulator is scalable, robust and validated to simulate large-scale CO₂ storage problems with hundreds of millions of grid blocks on a parallel supercomputer cluster. Besides, after our modification on scaling factors, the SAB method can reduce the number of stability analyses by 61.39 % to 88.71 %, thereby reducing simulation time. Furthermore, case studies indicate that injecting O₂ and H₂ along with CO₂ reduces the stability or capacity of CO₂ storage and increases the pressure required for injection. However, this impact is not significant when the impurity content is less than 10 %.</p>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":" ","pages":"177065"},"PeriodicalIF":8.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behaviour of M. aeruginosa-Microplastic composite pollutants in coagulation and sludge storage.","authors":"Zehui Yu, Xuqi Li, Zheng Li, Zhaoyu Wang, Yan Jin, Hangzhou Xu","doi":"10.1016/j.scitotenv.2024.177176","DOIUrl":"10.1016/j.scitotenv.2024.177176","url":null,"abstract":"<p><p>Microcystis aeruginosa (M. aeruginosa) blooms and microplastics pollution have been major global water pollution concern in lakes and reservoirs. In this study, the behaviour of M. aeruginosa-microplastic composite pollutants in inorganic coagulant (PACl) and organic coagulant (HTCC) treatment was investigated. Results showed that, in coagulation stage, the dissolved extracellular polymers secreted by M. aeruginosa could promote the adhesion of microplastics to algae, so as to combine them into the algal flocs, thus improving the sedimentation and removal efficiency of microplastics. On the other hand, whilst microplastics increased the size of algal flocs in PACl coagulation and improved algal removal efficiency, they had the opposite effect on HTCC coagulation. And the removal of algal metabolites including microcystins were improved by the presence of microplastics. In sludge storage stage, the oxidative and mechanical damage effects of microplastics promoted the rupture of M. aeruginosa cells in PACl sludge but not in HTCC sludge, which mean more potential risks in recycling of PACl sludge water. Besides, microplastics promoted the proliferation of beneficial bacteria such as Poterioochromonas and Coccomyxa, which contributed to the control of sludge pollution.</p>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":" ","pages":"177176"},"PeriodicalIF":8.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term investigation on the daily variability of microplastic concentration and composition - Monitoring in the effluent of a wastewater treatment plant.","authors":"Cordula S Witzig, Peter Fiener, Nicole Zumbülte","doi":"10.1016/j.scitotenv.2024.177067","DOIUrl":"10.1016/j.scitotenv.2024.177067","url":null,"abstract":"<p><p>The discharge of treated wastewater into receiving waters by wastewater treatment plants (WWTPs) is considered as one of the main pathways for microplastics (MPs) to enter the environment. To gain a better understanding of the temporal variability of MPs in WWTP effluents, this study investigated the concentration and composition (size, shape and polymer type) of MPs in the effluent of a German WWTP over the course of one month. 24-hour mixed samples were collected daily by a custom built automated sampling unit for MPs. Particles and fibers ≥11 μm were analyzed using Fourier transform infrared microspectroscopy. The MP concentration showed large daily fluctuations and ranged between 9.64 10³ m^-3 and 8.44 10⁴ m^-3 MPs over the study period. However, there was no significant correlation between the MP concentration and the precipitation or discharge from the WWTP. In contrast to the MP concentration, the MP composition in terms of size and shape was consistent over the study period. There were strong correlations between the time series of the polymer types polypropylene, polyethylene, polystyrene, polyester, ethylene-vinyl-acetate, cellulose artificially modified as well as the polymer cluster acrylates/polyurethanes/varnish. The time series of polyamide showed no significant correlation with the time series of any other polymer type. This study established a one month long high-resolution time series of MP concentration and composition, and thus provides a valuable basis for future research on the temporal variability of MP inputs into the environment from WWTP effluents.</p>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":" ","pages":"177067"},"PeriodicalIF":8.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Climate change is intensifying rainfall erosivity and soil erosion in West Africa.","authors":"Oluwafemi E Adeyeri, Akinleye H Folorunsho, Tolulope E Adeliyi, Kayode I Ayegbusi, Akintomide A Akinsanola, Christopher E Ndehedehe, Naveed Ahmed, Toju E Babalola","doi":"10.1016/j.scitotenv.2024.177174","DOIUrl":"10.1016/j.scitotenv.2024.177174","url":null,"abstract":"<p><p>Soil erosion is a critical environmental challenge with significant implications for agriculture, water quality, and ecosystem stability. Understanding its dynamics is essential for sustainable environmental management and societal welfare. Here, we analyze rainfall erosivity and erosion patterns across West Africa (WAF) during the historical (1982-2014), near future (2028-2060), and far future (2068-2100) periods under Shared Socioeconomic Pathways (SSPs 370 and 585). Using bias-corrected-downscaled (BCD) climate models validated against reference data, we ensure an accurate representation of rainfall-a key driver of erosivity (R-factor) and soil erosion. We compare Renard's approach and the Modified Fournier Index (MFI) to calculate the R-factor and note a strong correlation. However, Renard's method shows slightly lower accuracy in Sierra Leone, Guinea, and The Gambia, likely due to its inability to capture high-intensity, short-duration rainfall events. In contrast, the MFI, utilizing continuous rain gauge data, proves more reliable for these regions. We also attribute fluctuations in erosivity, such as those seen during the 2003 West Africa floods, to synoptic weather patterns influenced by multiple climate processes. Furthermore, our analysis reveals regions where future soil erosion could exceed 20 t/ha/yr due to climate change. Under the SSP 370 scenario, soil erosion in WAF is projected to rise by 14.84 % in the near future and 18.65 % in the far future, increasing further under SSP 585 to 19.86 % and 23.49 %, respectively. The most severe increases are expected in Benin and Nigeria, with Nigeria potentially facing a 66.41 % rise in erosion by the far future under SSP 585. These findings highlight the region's exposure to intensified climatic conditions and underscore the urgent need for targeted soil management and climate adaptation strategies to mitigate erosion's ecological and socioeconomic impacts.</p>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":" ","pages":"177174"},"PeriodicalIF":8.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detecting active sinkholes through combination of morphometric-cluster assessment and deformation precursors.","authors":"Yosef Darge, Esayas Gebremichael, John Holbrook, Mohamed Ahmed","doi":"10.1016/j.scitotenv.2024.177061","DOIUrl":"10.1016/j.scitotenv.2024.177061","url":null,"abstract":"<p><p>Sinkhole hazards pose considerable challenges in the west-central region of Texas. This study integrates multisource datasets and innovative techniques to detect early sinkhole development and identify the processes governing their formation. The techniques employed encompass feature extraction, cluster analysis, and deformation process monitoring. Potential sinkholes were initially mapped using high-resolution elevation data, and a circularity index (CI) threshold value of 0.85 was applied to filter out depressions with noncircular shapes. Subsequently, Persistent Scatterer Interferometry (PSInSAR) followed by the Getis-Ord Gi* statistic methods were used to identify statistically significant subsidence clusters with rates of <-2 mm/yr, indicating active sinkhole formation. The findings reveal the following: (1) surface deformation analysis revealed significant subsidence hotspots, particularly in areas underlain by units containing significant sequences of evaporites, which nominally belong to the Clear Fork Group and the Blaine Formation, compared with those dominated by carbonates; (2) potential sinkholes are undergoing displacement up to a rate of -11.31 mm/yr, and (3) extreme groundwater pumping of karst aquifers and the subsequent decline in groundwater levels are found to be the leading causes of the susceptibility of the region to sinkhole hazards. In such cases, the decline of the water table deprives the overlying bedrock of buoyant support provided by the groundwater in the cavity. The bedrock will undergo sagging subsidence under the influence of gravity and eventually form a sinkhole. Extensive oil and gas activity in the study area, including extreme withdrawal rates and the injection of fluids associated with the activity, are other potential causes of the observed sinkhole susceptibility in several parts of the study area. This study underscores the importance of understanding the geologic, hydrologic, and anthropogenic factors driving sinkhole hazards for effective mitigation strategies to protect public safety, infrastructure, and the environment.</p>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":" ","pages":"177061"},"PeriodicalIF":8.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeling impacts of indoor environmental variables on secondary organic aerosol formation.","authors":"Spencer Blau, Myoseon Jang","doi":"10.1016/j.scitotenv.2024.177036","DOIUrl":"10.1016/j.scitotenv.2024.177036","url":null,"abstract":"<p><p>There are numerous air pollutants indoors including chemicals emitted from building environments as well as outdoor-origin species due to human activities. Despite the significance of indoor air quality, the atmospheric process indoors is not well studied. In this study, the secondary organic aerosol (SOA) formation from the oxidation of α-pinene blended with toluene was simulated under varying indoor environments (lamps, NO₂, ozone, and inorganic seed) using the UNIfied Partitioning Aerosol Reaction (UNIPAR) model. Explicitly predicted lumping species produced during the atmospheric oxidation of precursors are used in the model and they process multiphase partitioning and aerosol phase reactions. The performance of the model was demonstrated using indoor chamber experiments in both dark conditions (ozonolysis) and light conditions with commercialized fluorescent or LED lamps. α-Pinene SOA was dominated by ozonolysis even in the presence of indoor light. Toluene, which is known to be photochemically processed, was oxidized in the dark condition with OH radicals that were derived from ozonolysis products of α-pinene. At given dark simulation conditions (10 ppb α-pinene, 30 ppb ozone, and 50 ppb of toluene), toluene contributed 15 % of SOA mass. α-Pinene SOA was insensitive to hygroscopicity of inorganic seed, but toluene blended with α-pinene increased the sensitivity to seed conditions due to the formation of oligomeric matter via aqueous reactions of reactive toluene products. In the presence of NO₂. α-pinene SOA formation significantly increased with increasing NO₂ owing to the reaction of α-pinene with nitrate radicals to form low volatile products. This study concludes that ozone and NO₂, intruded from outdoors to indoors, effectively oxidize terpenes and furthermore aromatic hydrocarbons with OH radicals originating from ozonolysis of terpenes. The reaction paths with ozone and nitrate radicals are more effective at forming SOA than that with OH radical under the indoor light condition with commercialized lamps.</p>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"955 ","pages":"177036"},"PeriodicalIF":8.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modifying factors and temporal trends of adverse health effects of short-term exposure to PM_2.5 in Canada (2001-2018).","authors":"Hwashin H Shin, James Owen, Anna O Delic, Muzeyyen Kabasakal, Stéphane Buteau","doi":"10.1016/j.scitotenv.2024.177046","DOIUrl":"10.1016/j.scitotenv.2024.177046","url":null,"abstract":"<p><p>Considerable evidence has been accumulated on serious acute health outcomes associated with short-term exposure to ambient fine particulate matter (PM_2.5). Modifying factors of those associations, however, have been less explored and need further analyses. In this national study, we investigated whether short-term effects of PM_2.5 are modified according to region, cause of mortality/hospitalization, season, age, and sex. PM_2.5-related adverse health effects were estimated by an ecological time-series study, covering about 80 % of the Canadian population for 18 years (2001-2018). We estimated city-specific associations using daily averages of PM_2.5 and temperature, and daily counts of hospitalizations and mortality (non-accidental all-cause, circulatory, and respiratory). National and regional associations were then estimated with a 2-stage model. We considered potential modifying factors of PM_2.5-related adverse health effects, and examined linear trends in the annual associations. Nationally, PM_2.5 exposure was associated with both hospitalizations and mortality, and there was evidence of differences by the modifying factors. Of the various causes, circulatory mortality and respiratory hospitalization were more attributable to PM_2.5 exposure. We found regional differences for both all-cause hospitalization and all-cause mortality, and seasonal differences for respiratory hospitalization (warm season) and circulatory hospitalization (cold season). Circulatory mortality risk was significant for seniors and females. All-cause hospitalizations appeared to gradually decrease over time, but annual all-cause mortality remained constant at 0.6 % of the population. Adverse health effects of PM_2.5 exposures may depend on not only PM_2.5 concentration, but also other factors (region, cause, season, age, sex). National estimates for the baseline (age ≥ 1 year, both sexes) risk cannot be interpreted without consideration of the differences by modifying factors. Study findings can be used by seniors, women, and those who have pre-existing health conditions to make informed decisions regarding their health risks from daily exposure to ambient PM_2.5.</p>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":" ","pages":"177046"},"PeriodicalIF":8.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trace antibiotic exposure affects murine gut microbiota and metabolism.","authors":"Chengfei Wang, Liang Zhao, Jian Xu, Xiaowei Li, Saiwa Liu, JingJing Du, Xixi Jia, Zhinan Wang, Lirui Ge, Zuhao Yan, Xi Xia","doi":"10.1016/j.scitotenv.2024.177033","DOIUrl":"10.1016/j.scitotenv.2024.177033","url":null,"abstract":"<p><p>Gut microbiota is important for host metabolism regulation. Antibiotic exposure disturbs this regulation by affecting the microbiome. Trace levels of antibiotics in water have been widely reported and the impact on gut microbiota remains understudied. We provide evidence of trace antibiotic exposure affecting the host's gut microbiota using a mouse model exposed to trace amounts of azithromycin (AZI) or ciprofloxacin (CIP) in drinking water. AZI exposure in males changed the distribution of gram-positive (Firmicutes and Bacteroidetes) and gram-negative (Proteobacteria, Fusobacteria, and Verrucomicrobia) bacteria at an early age. Both AZI and CIP resulted in abnormal microbiota maturation. Additionally, the production of short-chain fatty acids (SCFAs), including acetate, butyrate, and propionate, in females is affected. Serum hormone and metabolome levels shifted after trace antibiotic exposure. AZI and CIP exposure broadly disrupted original host-microbe interaction relationships between the gut microbiota and SCFAs or serum metabolites. In this study, we demonstrated that trace antibiotic exposure was associated with extensive gut microbiota and metabolism perturbation in mice and that the potential health risks in susceptible populations should be considered.</p>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"955 ","pages":"177033"},"PeriodicalIF":8.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}