环境科学与生态学最新文献

{"title":"An insight into sediment fractionation analysis: from sampling to visualisation of results","authors":"Nicolas Nario ,&nbsp;Natalia A. Gomez ,&nbsp;Vanesa L. Negrin ,&nbsp;Mónica B. Alvarez ,&nbsp;Jorge E. Marcovecchio ,&nbsp;Mariano Garrido ,&nbsp;Claudia E. Domini","doi":"10.1016/j.marpolbul.2025.118149","DOIUrl":"10.1016/j.marpolbul.2025.118149","url":null,"abstract":"<div><div>This review is focused on the importance of operational conditions for metal fractionation and their influence on the results obtained, using both sequential and single step extractions. The discussion is about the different pathways by which metals are incorporated into aquatic systems and the relationship between the nature of sediments and their interaction with metals. In addition, the relevance of the so-called metal extraction methods, either sequential or single-step extractions, to obtain information about the bioavailability and mobility of metals in sediments is considered. Several aspects, such as sampling and sample storage, sediment processing (drying and sieving), sediment mass/extractant volume ratio and operational time, are reviewed since they can significantly affect the recoveries of metals associated with each geochemical phase. Finally, chemometric techniques are addressed as useful tools to visualise and interpret the data obtained and transform them into relevant information. Although a variety of reagents and operating conditions have been used with satisfactory results, there are no standardised protocols, with the exception of the BCR, which has undergone successive modifications. This shows that even the best combination of extractants can have advantages and limitations, and the use of one protocol or another will depend on the type of information required. In this sense, the experimental conditions play a relevant role in obtaining reliable information on the mobility and availability of metals.</div></div>","PeriodicalId":18215,"journal":{"name":"Marine pollution bulletin","volume":"218 ","pages":"Article 118149"},"PeriodicalIF":5.3,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin K2 prevents postoperative cognitive impairments, anxiety-like behavior, and motor dysfunction induced by nanoplastics in young adult mice","authors":"Yu Hou ,&nbsp;Shuai Li ,&nbsp;Jian Yu ,&nbsp;Qi Hou ,&nbsp;Runjia Wang ,&nbsp;Xueran Xu ,&nbsp;Xiyuan Xu ,&nbsp;Zhichao Li ,&nbsp;Linhui Ma ,&nbsp;Qidong Liu ,&nbsp;Yuan Shen ,&nbsp;Guotao Peng ,&nbsp;Hui Zheng","doi":"10.1016/j.ecoenv.2025.118318","DOIUrl":"10.1016/j.ecoenv.2025.118318","url":null,"abstract":"<div><div>Nanoplastics (NPs) pollution poses serious health risks and worsens various diseases. However, its role in postoperative complications, particularly perioperative neurocognitive disorders (PNDs), remains unclear. While PNDs are common in the elderly and rare in young adults, lifelong and cumulative exposure to NPs may increase the susceptibility of young individuals to PNDs. Herein, surgery alone caused no neurobehavioral impairments in young adult male and female mice and exposed to NPs alone exhibited anxiety-like behavior. However, young adult male and female mice exposed to NPs for 30 days, with surgery on day 31, exhibited postoperative cognitive impairment and anxiety-like behavior associated with PNDs, along with motor dysfunction. Vitamin K2 (VK2) pretreatment mitigated the behavioral impairments induced by nanoplastics and surgery (NS) exposure. RNA sequencing and bioinformatics analysis of male mice revealed that NS activated inflammatory and cell death pathways in the hippocampus (HIP), with upregulation of key genes such as Selp, Timp1, and Emp3. In the medial prefrontal cortex (mPFC), NS exposure upregulated pathways associated with neuronal apoptosis, reactive oxygen species (ROS) processes, and cell death, accompanied by dysregulated expression of genes such as Tert, Adam8, Esr2, and Emp3. VK2 pretreatment rescued these molecular alterations by normalizing the expression of key genes. Additionally, VK2 reduced levels of IL-1β, TNF-α, IL-6, ROS and MDA, while attenuating brain cell apoptosis and microglial activation in the HIP and mPFC of male mice. This study demonstrates that NS exposure increases the susceptibility of young adults to PNDs and highlights VK2 as a promising preventive strategy. Moreover, it elucidates critical molecular pathways and genes, providing a solid foundation for future research.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"298 ","pages":"Article 118318"},"PeriodicalIF":6.2,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing multiscale sustainable development in lake-dense regions: A dynamic management chain for ecosystem service supply–demand and ecological risks interactions","authors":"Suwen Xiong ,&nbsp;Fan Yang ,&nbsp;Jingyi Zhang ,&nbsp;Jiayu Li ,&nbsp;Chuntian Gu","doi":"10.1016/j.jenvman.2025.125737","DOIUrl":"10.1016/j.jenvman.2025.125737","url":null,"abstract":"<div><div>Dynamic management of lake-dense regions based on interactions between ecosystem service supply–demand (ESSD) and ecological risk (ER) is essential for sustainable development. This study integrates the ecosystem service value supply model, a land–population–economy–society demand model, and the landscape ER assessment to develop a comprehensive ESSD–ER framework for lake-dense regions. Bivariate spatial autocorrelation and geographically and temporally weighted regression (GTWR) models are applied to reveal the spatiotemporal interaction intensity between ESSD and ER. Subsequently, an integrated ESSD–ER sustainable management framework is constructed based on a six-quadrant model and dynamic change rate index. Applying this framework to the middle reaches of the Yangtze River urban agglomerations (MRYRUA) at multiscale, the results indicate: (1) A persistent mismatch existed in the study area, where ecosystem service supply remains lower than demand, with ER rising annually. (2) High ESSD–high ER clusters showed positive interactions within lake areas. Negative interactions intensify progressively from low–high clustered nearshore areas to high–low clustered inland forested areas. (3) MRYRUA comprised six management zones: optimal balance sustainable zones, potential balance sustainable zones, imbalanced improvement transitional zones, worsening imbalance transitional zones, risk alert transitional zones, and dual crisis unsustainable zones. At the macroscale, northern regions displayed higher unsustainable categories than southern regions, showing apparent spatial heterogeneity. Risk-alert transitional zones dominated (51.61 %), primarily distributed adjacent to water bodies. At the microscale, cropland–forest interlaced zones serve as optimal balance sustainable zones. Green industrial upgrading mechanisms are recommended in dual crisis unsustainable zones in northern regions. Southern regions should maintain their advantages in optimal and potential balance sustainable zones. These findings provide scientific guidance to achieve multiscale sustainable development in lake-dense regions.</div></div>","PeriodicalId":356,"journal":{"name":"Journal of Environmental Management","volume":"386 ","pages":"Article 125737"},"PeriodicalIF":8.0,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144070684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Towards transformative change for biodiversity: What can we learn from case studies in Germany?","authors":"Vera Schreiner ,&nbsp;Marion Mehring ,&nbsp;Janina Kleemann ,&nbsp;Jennifer Hauck ,&nbsp;Stefan Knauß ,&nbsp;Christian Poßer ,&nbsp;Christian Schleyer ,&nbsp;Thomas Potthast ,&nbsp;Karsten Grunewald ,&nbsp;Christine Fürst ,&nbsp;Jennifer Müller ,&nbsp;Christian Albert ,&nbsp;Monika Egerer ,&nbsp;Dagmar Haase ,&nbsp;Sonja C. Jähnig ,&nbsp;Josef Kaiser ,&nbsp;Tanja GM. Sanders ,&nbsp;Pia Sommer ,&nbsp;Thilo Wellmann ,&nbsp;Peter Keil ,&nbsp;Heidi Wittmer","doi":"10.1016/j.jenvman.2025.125663","DOIUrl":"10.1016/j.jenvman.2025.125663","url":null,"abstract":"<div><div>Current human activities have led to fundamental changes in ecosystems, including the loss of biodiversity, which increasingly leads to irreversible negative impacts on society. Although called for in many policy documents, the debate on how to initiate, promote and specifically support socio-ecological transformations for the conservation and restoration of biodiversity is still in its early stages. So far, efforts to protect biodiversity were only partially successful. Therefore, there is a need for approaches to promote societal change for the benefit of biodiversity. We analysed 22 case studies of biodiversity-enhancing societal processes and projects in Germany to understand barriers and success factors and to identify features that support transformative change towards sustainability and biodiversity mainstreaming. Following Wittmer et al. (2021), the following topics were analysed: a) orientation towards a shared and compelling vision that enables biodiversity conservation or enhancement (transformative vision), b) the role of (different types of) knowledge about how to change the system (transformative knowledge), c) navigating the dynamics inherent in changing development pathways (transformational dynamics), d) enabling emancipated action and opening spaces for creative participation of different social groups (emancipation and agency), and e) targeted interventions that aim to enable governance for transformation. This article discusses lessons learned from examples in Germany to support future transformative processes for biodiversity conservation, restoration and biodiversity mainstreaming. It identifies 16 features, enabling transformative change for biodiversity, many of which may be applicable in other countries with similar governance contexts. These characteristics suggest that a structured and well-informed approach, based on a broad range of communication, engagement, negotiation, and stakeholder involvement efforts throughout the process, is well-suited for developing and implementing proposals. While in some small cases indirect drivers were addressed, achieving this on a broader scale is the largest remaining challenge.</div></div>","PeriodicalId":356,"journal":{"name":"Journal of Environmental Management","volume":"386 ","pages":"Article 125663"},"PeriodicalIF":8.0,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144070686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy Use During Flight Impacts Semiochemical Response in the Mountain Pine Beetle.","authors":"L Petro, A E Musso, M L Evenden","doi":"10.1007/s10886-025-01610-5","DOIUrl":"https://doi.org/10.1007/s10886-025-01610-5","url":null,"abstract":"<p><p>Global climate change drives the range expansion of various taxa, including the mountain pine beetle (Dendroctonus ponderosae; MPB). Dispersal and host colonization dictate spread and establishment of MPB populations, but this comes with energetic, time, risk, and opportunity costs. As MPB exhibit continuous flight polyphenisms, researchers have proposed that energy use during flight may trigger responsiveness to the semiochemicals that orchestrate the colonization of host pine trees, but this effect has not been demonstrated empirically. Here, we test the hypothesis that flight exercise impacts subsequent behavioral response to semiochemicals in two olfactometer experiments that simulate 1) female beetle pioneer response to host volatiles and 2) male and female joining beetle response to host volatiles and the female-produced aggregation pheromone, trans-verbenol. We also assess antennal response of female beetles to α-pinene post-flight in an electroantennogram bioassay. Female MPB with low condition due to energy expenditure responded strongly to host semiochemicals post-flight. The antennal response of female MPB to the host volatile α-pinene increased with relative lipid content of beetles. Male behavioral response to semiochemicals was not influenced by body condition or exercise by flight. The effect of flight and body condition on orientation to semiochemical cues may influence individual dispersal patterns. These findings should be considered in the refinement of dispersal models that incorporate individual variability to predict spread of MPB in its expanded range.</p>","PeriodicalId":15346,"journal":{"name":"Journal of Chemical Ecology","volume":"51 3","pages":"54"},"PeriodicalIF":2.2,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between maternal exposure to ten neonicotinoid insecticides and preterm birth in Guangxi, China","authors":"Dongxiang Pan, Lihong Zhou, Changhui Mu, Mengrui Lin, Xiaogang Wang, Qian Liao, Lidi Lei, Shun Liu, Dongping Huang, Xiaoqiang Qiu, Xiaoyun Zeng","doi":"10.1016/j.envpol.2025.126477","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.126477","url":null,"abstract":"Preterm birth (PTB) is a primary cause of mortality among newborns globally. Prenatal exposure to environmental pollutants has been suggested to increase the PTB risk. Studies have shown NEOs may be linked to adverse birth outcomes. However, the impact of maternal NEOs exposure on PTB remains unclear. Therefore, to examine the association between NEOs exposure and PTB risk, we performed a case-control analysis utilizing data from a birth cohort study in Guangxi, China. A total of 157 preterm infants and 471 full-term infants were included. Concentrations of 10 NEOs and their metabolites in maternal serum were quantified using liquid chromatography-tandem mass spectrometry. We employed logistic regression, quantile g-computation, and restricted cubic spline models to evaluate the effects of individual and mixed NEO exposures. Subsequently, XGBoost machine learning, combined with SHAP, was employed to predict the implications of serum NEOs on PTB. Finally, for 1-standard deviation increment in ln-transformed concentrations of imidacloprid and dinotefuran, significant correlations with higher odds of PTB were observed, showing odds ratios of 1.17 (95% CI: 1.02, 1.36) and 1.41 (95% CI: 1.16, 1.72). Similar patterns and higher risks were observed in late preterm birth. In both mixed exposure and machine learning models, DIN and IMI were identified as major predictors of increased PTB risk. Exposure to n-desmethylacetamiprid, sulfoxaflor, thiacloprid, nitenpyram, and thiamethoxam was negatively associated with PTB. Our findings suggested dinotefuran and imidacloprid exposure during pregnancy were risk factors of PTB, particularly among late preterm births. Subsequent research is necessary to illuminate the underlying mechanisms involved.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"2 1","pages":"126477"},"PeriodicalIF":8.9,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Quassia indica derived synthesis of Co₃O₄/ZnO nanohybrids for efficient dye degradation and cytotoxicity assessment.","authors":"Shilpa Susan Scaria, Kadanthottu Sebastian Joseph","doi":"10.1007/s11356-025-36502-4","DOIUrl":"https://doi.org/10.1007/s11356-025-36502-4","url":null,"abstract":"<p><p>While there are exciting possibilities in nanotechnology, creating environmentally safe nanoparticles with a variety of uses in photocatalysis and biomedicine continues to be a significant issue. This work addresses the gap by introducing Quassia indica leaf extract as a bio reductant and stabilizer in the green synthesis of cobalt oxide-zinc oxide nanoparticles (QI: Co₃O₄/ZnO NP). The synthesized nanoparticles were characterized using various techniques, including UV-visible spectroscopy, X-ray diffraction (XRD), dynamic light scattering (DLS), high resolution transmission electron microscopy (HR-TEM), selected area electron diffraction (SAED), Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FE-SEM), and energy dispersive X-ray spectroscopy (EDX). The existence of hexagonal zinc oxide and cubic cobalt oxide phases in the synthesized nanoparticles was verified by XRD analysis. The elemental composition was confirmed by EDX, which showed that oxygen, zinc, and cobalt were present. The average hydrodynamic diameter of 244.5 d. nm was found via DLS measurements, indicating well dispersed nanoparticles. Under UV light irradiation, photocatalytic activity of QI: Co₃O₄/ZnO NP was assessed for the degradation of textile dyes (Reactive Blue-222, Reactive Blue-220, Reactive Red-120, and Reactive Yellow-145). Phytotoxicity tests were conducted to examine the possible environmental impact of the deteriorated dye solution, revealing promising results in mitigating the detrimental impact of industrial dyes. QI: Co₃O₄/ZnO NP was also assessed for cytotoxicity studies in DLA and EAC cells which showed a concentration-dependent cytotoxic effect. The research outcomes emphasize the significant potential of these nanoparticles in diverse arena by offering a sustainable and efficacious resolution to the present-day problems.</p>","PeriodicalId":545,"journal":{"name":"Environmental Science and Pollution Research","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Turnover shapes evolution of birth and death rates.","authors":"Teemu Kuosmanen, Simo Sa Rkka, Ville Mustonen","doi":"10.1093/evolut/qpaf076","DOIUrl":"https://doi.org/10.1093/evolut/qpaf076","url":null,"abstract":"<p><p>A truly predictive evolutionary theory must be derived self-consistently from the underlying stochastic population dynamics, where the environment and ecology are not treated merely as confounders and mediators of evolutionary dynamics. By explicitly decomposing fitness to its birth and death components as well as accounting for how evolution and ecology respectively might affect them, we show how a fundamental asymmetry between reproduction and survival emerges. First, we derive a stochastic replicator equation from a general birth-death process and demonstrate the importance of the demographic turnover rate (defined as the sum of birth and death rates) on mutant fixation. Then we show how the turnover rate shapes the distribution of evolutionary trajectories causing a systematic turnover bias in the mutant substitution dynamics in favour of less volatile low-turnover strategies. Finally, we provide theory for predicting how organismal growth strategies evolve in response to different population regulation mechanisms and show how the resulting life-history evolution has a clear direction where the pace of life becomes either slower or faster depending on the ecological context and mutational supply. Overall, our results highlight the importance of demographic turnover in evolution and underline the perils of quantifying fitness with a single parameter.</p>","PeriodicalId":12082,"journal":{"name":"Evolution","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intensified atmospheric aridity in East Africa under future climate change","authors":"Kidane Welde Reda ,&nbsp;Xingcai Liu ,&nbsp;Qiuhong Tang ,&nbsp;Gebremedhin Gebremeskel Haile ,&nbsp;Yongdong Wang ,&nbsp;Ayalkibet Mekonnen Seka","doi":"10.1016/j.jaridenv.2025.105402","DOIUrl":"10.1016/j.jaridenv.2025.105402","url":null,"abstract":"<div><div>Vapor pressure deficit (VPD) plays a critical role in regulating water and CO₂ exchanges between land and atmosphere, particularly in climate-vulnerable regions. This study investigated historical and future patterns of VPD using state-of-the-art datasets, including ERA5, CRU TS, MERRA2, and five general circulation models (GCMs) from the Inter-Sectoral Impact Model Inter-comparison Project (ISIMIP) over East Africa. Trends were analyzed annually and seasonally for the historical period (1981–2022), near future (2023–2061), and distant future (2063–2100), along with contributions from temperature, relative humidity, and air pressure to future VPD changes. Results showed that VPD increased annually by 0.04 hPa year⁻¹ from 1981 to 2022, with the most significant rise in dry regions. Future projections indicate continued VPD increases at both annual and seasonal scales, intensifying in accordance with the magnitude of CO₂ emission scenarios (SSP126, SSP370, and SSP585, respectively). Under SSP585 and SSP370 the annual VPD is projected to increase by 0.06 and 0.05 hPa year⁻¹, respectively from 2023 to 2100. The summer season exhibits the highest rate of increase, followed by spring, across all scenarios. This substantial change in VPD during the summer season will significantly impact the agricultural sector of the region. Furthermore, the contribution of temperature increase (148 %–162 %) to the projected increase in VPD outweighs that of relative humidity (−99 % to −117 %) and air pressure (51 %–55 %) changes across the scenarios. Thus, the increasing VPD is expected to have a significant impact on the ecosystems of the East Africa by exacerbating drought conditions.</div></div>","PeriodicalId":51080,"journal":{"name":"Journal of Arid Environments","volume":"229 ","pages":"Article 105402"},"PeriodicalIF":2.6,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green hospitals: maximizing health and climate benefits globally","authors":"David Rojas-Rueda","doi":"10.1016/j.scitotenv.2025.179692","DOIUrl":"10.1016/j.scitotenv.2025.179692","url":null,"abstract":"<div><div>Climate change poses unprecedented challenges to global health, with the healthcare sector itself contributing significantly to greenhouse gas emissions. This perspective presents an innovative, adaptable framework for integrating sustainable and climate-friendly practices into healthcare settings across diverse economic contexts. We examine energy efficiency, waste management, water sustainability, supply chain optimization, telemedicine, and biophilic design in healthcare. The framework provides implementation strategies, cross-cutting climate innovations, and explores interconnections between climate-smart healthcare, health equity, and global sustainability. Our findings suggest that implementing climate-smart healthcare can lead to significant reductions in carbon emissions, enhanced resilience to climate-related health threats, and improved health outcomes globally. We conclude that the healthcare sector can transform from a significant contributor to climate change into a leader in climate mitigation and adaptation, creating a more sustainable, resilient, and equitable global health system.</div></div>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"982 ","pages":"Article 179692"},"PeriodicalIF":8.2,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144070451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}