{"title":"Patient-specific three-dimensional-printed models for canine adrenalectomy: a report of three cases.","authors":"M Rigo, A Pratesi, G Bertolini, F Cinti","doi":"10.1080/00480169.2025.2511195","DOIUrl":"10.1080/00480169.2025.2511195","url":null,"abstract":"<p><p><b>Case history:</b> Three dogs with adrenal masses scheduled for adrenalectomy were prospectively enrolled into a study to investigate the effectiveness of a 1:1-scale, three-dimensional (3D) printed model of neoplastic adrenal glands to aid surgical planning and provide intra-operative assistance during adrenalectomy in dogs.Case 1 presented with anorexia, lethargy and a distended abdomen; Case 2 with loss of appetite, behavioural changes, and vocalisation; and Case 3 with mild inappetence during the previous 15 days.<b>Clinical and imaging findings:</b> On physical examination, mild abdominal pain was noted in all cases. Case 1 was consistently mildly hypertensive over repeated measurements. All cases had mild or moderate elevations in the activities of alanine aminotransferase and aspartate aminotransferase, and the concentration of C-reactive protein. Cases 1 and 2 also had mild leucocytosis. Abdominal CT revealed a left-sided adrenal tumour with caval invasion in Case 1, and right-sided adrenal tumours without caval invasion in Cases 2 and 3. 3D-printed models were created from the CT scan. Different colours were assigned to anatomical structures for better visualisation. Measurements of six anatomical landmarks were made on CT images and on the 3D-printed model. The median absolute difference in measurements taken from the model and the CT scan was 0.75 (min 0, max 3.2) mm.<b>Treatment and outcome:</b> All dogs underwent surgical removal of the adrenal tumour via sterno-pubic celiotomy. Placing the 3D model on the operating table in the same orientation as the patient allowed for precise pre-planning of the dissection depth. Printed without the fat, and fibrous and capsular tissues that typically cover the retroperitoneal space, the model helped the surgeon to visualise vascular structures that were still covered by connective tissue in the patient. Subjectively, the use of 3D models improved surgical planning and execution by enhancing the understanding of anatomical relationships and enabling the accurate identification of surgical landmarks.No major intra-operative complications were reported. Post-operative outcomes were favourable, with no significant complications observed.<b>Clinical relevance:</b> The use of 3D-printed models in adrenal surgeries for dogs may enhance the surgeon's spatial awareness and intra-operative confidence. We recommend that these models are used in conjunction with CT imaging for effective pre-operative planning. Further research with larger sample sizes and a control group would allow a fuller exploration of the benefits of 3D-printed models in veterinary surgical practices.<b>Abbreviations:</b> ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; CRP: C-reactive protein; CVC: Caudal vena cava; 3D: Three-dimensional.</p>","PeriodicalId":19322,"journal":{"name":"New Zealand veterinary journal","volume":" ","pages":"370-378"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosis, Classification, and Treatment of Canine Tooth Resorption: A Literature Review.","authors":"Emily Baldwin, Melissa Guillory, Patrick Vall","doi":"10.1177/08987564241295330","DOIUrl":"10.1177/08987564241295330","url":null,"abstract":"<p><p>Tooth resorption is a common finding in imaging and oral examination of the canine veterinary dental patient. Although significant literature exists on tooth resorption in the feline, available canine tooth resorption publications are sparse. This article aims to provide a comprehensive literature review of canine tooth resorption, including diagnosis, classification, and treatment.</p>","PeriodicalId":17584,"journal":{"name":"Journal of Veterinary Dentistry","volume":" ","pages":"372-381"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S McDougall, J Williamson, J Lacy-Hulbert, N Steele, C Eastwood
{"title":"Clinical and subclinical mastitis incidence in pasture-based dairy cows.","authors":"S McDougall, J Williamson, J Lacy-Hulbert, N Steele, C Eastwood","doi":"10.1080/00480169.2025.2487672","DOIUrl":"10.1080/00480169.2025.2487672","url":null,"abstract":"<p><strong>Aims: </strong>To estimate prevalence and incidence of intramammary infections (IMI) using herd test somatic cell counts (SCC) or quarter-level microbiology in a single pasture-based, seasonal calving dairy herd.</p><p><strong>Methods: </strong>Over four seasons (2010/11-2013/14) milk samples were collected for microbiology from quarters of all cows at four times; calving, MID1 (mean 116 (SD 21) days in milk (DIM)), MID2 (mean 204 (SD 21) DIM), and at drying off (DO; mean 266 (SD 30) DIM). SCC was determined every 1-4 (median = 2) weeks. Quarters were defined as having a new IMI if a bacterium was isolated that was not present at the preceding milk sampling and a cow was defined as having a new IMI where one or more quarters had a new IMI. Cows were defined as having a new high SCC where SCC increased to ≥ 200,000 cells/mL. Binary logistic regression and Poisson models were used to estimate prevalence and incidence rate (IR) of new infections. Cow-level IR estimates from bacteriology and SCC were compared using χ<sup>2</sup> analyses, and the sensitivity and specificity were estimated for SCC to estimate IR, assuming bacteriology was the gold standard.</p><p><strong>Results: </strong>The prevalence of cows with a high SCC was 12.7 (95% CI = 12.3-13.1)% and quarter-level prevalence of IMI was 10.7 (95% CI = 10.2-11.1)%. The unadjusted IR for a new cow-level high SCC was 2.2 (95% CI = 2.0-2.4)/1,000 cow-days and for a new quarter-level IMI was 0.82 (95% CI = 0.71-0.95)/1,000 quarter-days at risk. Prevalence and IR were associated with DIM (p < 0.001), age (p < 0.001), and season (p < 0.001). The agreement between the IR based on herd test SCC and microbiology at cow-level was 77.1% (p < 0.001), with the level of agreement highest in mid-lactation. The sensitivity and specificity of an increase in SCC were 29.8% and 88.9%, respectively.</p><p><strong>Conclusions: </strong>Prevalence and IR varied by season, age and DIM. While the IR estimates differed between estimates based on a high SCC at the cow-level, and quarter-level microbiology, the level of agreement was 77% suggesting utility of cow-composite SCC data as a mastitis monitoring tool. However, the sensitivity of incidence based on elevated SCC was only approximately 30% relative to quarter-level microbiology as the gold standard.</p><p><strong>Clinical relevance: </strong>This study provides the first estimates of prevalence and incidence of IMI in pasture-based dairy cows.<b>Abbreviations:</b> DIM: Days in milk; DO: Dry Off; EMM: Estimated marginal mean; IMI: Intramammary infection; IR: Incidence rate; NAS: Non-aureus staphylococci; SCC: Somatic cell count; TAR: Time at risk.</p>","PeriodicalId":19322,"journal":{"name":"New Zealand veterinary journal","volume":" ","pages":"316-327"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toceranib phosphate for treatment of hypercalcaemia of malignancy in two dogs with metastatic anal sac apocrine gland adenocarcinoma.","authors":"J Morey, L Brockley","doi":"10.1080/00480169.2025.2486999","DOIUrl":"10.1080/00480169.2025.2486999","url":null,"abstract":"<p><strong>Case history: </strong>Two dogs, a 10-year-old male Siberian Husky cross and an 11-year-old male Cocker Spaniel were referred to a specialist veterinary hospital in Melbourne, Australia, for treatment of metastatic anal sac apocrine gland adenocarcinoma (ASAGAC) and concurrent hypercalcaemia (concentration of ionised calcium in serum > 1.5 mmol/L) of malignancy.</p><p><strong>Clinical findings: </strong>Case 1 had a left anal sac mass approximately 5.5 cm in diameter, enlarged sub-lumbar lymph nodes palpable on rectal examination and a concentration of ionised calcium in serum of 2.45 (reference range 1.2-1.32) mmol/L. Soft tissue opacities suspicious for metastatic pulmonary nodules were observed on thoracic radiographs. CT of Case 2 revealed bilateral anal gland masses (left: 4.7 × 3.2 cm; right: 2.8 × 2.1 cm) and a large, ill-defined, intrapelvic mass (7.0 × 6.0 cm) encompassing the medial iliac and internal iliac lymph nodes and intimately associated with the aortic blood vessels. Cytology of fine-needle aspirates of the anal gland masses of both dogs was consistent with ASAGAC. The owners of both dogs declined surgical intervention and medical management with toceranib phosphate was initiated in the gross disease setting.</p><p><strong>Treatment and outcome: </strong>Toceranib was initially administered at a dose of 2.5 mg/kg orally every other day in both dogs. Due to side effects from this medication, including hypocalcaemia, the dosing schedule was adjusted to Monday, Wednesday, and Friday with a dose range of 2.25-2.5 mg/kg. Both dogs remained alive, Case 1 after 519 days and Case 2 after 477 days, and were normocalcaemic at the time of writing. Both dogs experienced resolution of hypercalcaemia of malignancy while being treated with toceranib alone: hypercalcaemia was controlled for a total of 12 months in Case 1 and 15 months in Case 2. During treatment the anal sac mass of Case 1 remained approximately 5 cm in diameter and the sub-lumbar lymph node remained subjectively stable though no objective measurements were taken. Case 2's anal sac masses and intrapelvic lymph node mass subjectively reduced in size based on palpation.</p><p><strong>Clinical relevance: </strong>This case series highlights two instances where toceranib monotherapy effectively managed hypercalcaemia of malignancy secondary to metastatic ASAGAC. Despite the presence of extensive macroscopic neoplastic disease, both dogs achieved durable control of hypercalcaemia with toceranib treatment.<b>Abbreviations:</b> ASAGAC: Anal sac apocrine gland adenocarcinoma; cRECIST: Canine response evaluation criteria in solid tumours; HHM: Humoral hypercalcaemia of malignancy; OST: Overall survival time; PFS: Progression-free survival; PTH: Parathyroid hormone; PTHrP: Parathyroid-related hormone peptide; RTK: Receptor tyrosine kinase; TKI: Tyrosine kinase inhibitor.</p>","PeriodicalId":19322,"journal":{"name":"New Zealand veterinary journal","volume":" ","pages":"337-344"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adélia Ferreira Dargère, Josane Cardim de Jesus, Sibelli Passini Barbosa Ferrão, Leandro Soares Santos, Peter Bitencourt Faria
{"title":"A multivariate approach to verify correlations between sensory quality indices and analytical quality indices in traditional Brazilian cheese.","authors":"Adélia Ferreira Dargère, Josane Cardim de Jesus, Sibelli Passini Barbosa Ferrão, Leandro Soares Santos, Peter Bitencourt Faria","doi":"10.1007/s13197-024-06145-3","DOIUrl":"https://doi.org/10.1007/s13197-024-06145-3","url":null,"abstract":"<p><p>Artisanal Minas cheese (AMC) is a traditional Brazilian cheese that combines particular production techniques and maturation conditions resulting in cheeses with unique sensory properties. The objective was to use multivariate statistical to determine a quality index based on the correlation of sensory and instrumental analyses of AMC. 25 samples were obtained from a cheese contest, which were sensorially evaluated by judges. Composition, lipid oxidation, fatty acid and volatile compound profiles were analyzed. The data were analyzed using principal component analysis (PCA) and canonical correlation analysis (CCA). PCA helped identify the key variables that distinguished different types of cheeses based on their qualities. CCA showed that hardness and lipid oxidation are indicators of the sensorial quality of cheeses, parameters that classified the cheeses in the competition, with the best evaluated having higher levels of these attributes.</p>","PeriodicalId":16004,"journal":{"name":"Journal of Food Science and Technology-mysore","volume":"62 9","pages":"1764-1771"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12304404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Isolation and characterization of novel <i>Lacticaseibacillus</i>, <i>Pediococcus, Enterococcus, Lentilactobacillus,</i> and <i>Levilactobacillus</i> strains with probiotic potential from fermented turnip juice.","authors":"Ilkin Sengun, Husniye Tansel Yalcin, Gulden Kilic, Aysegul Kirmizigul Peker, Berna Ozturk, Yigit Terzi","doi":"10.1007/s13197-024-06133-7","DOIUrl":"https://doi.org/10.1007/s13197-024-06133-7","url":null,"abstract":"<p><p>Lactic acid bacteria (LAB) isolates (29 isolates) from fermented turnip juices were identified using 16S rRNA gene sequencing techniques. The findings indicated that the most common strains belonged to <i>Lacticaseibacillus</i> sp. (55.17%), <i>Pediococcus acidilactici</i> (27.58%), and <i>Enterococcus faecalis</i> (6.89%). According to the results, all strains exhibited high resistance to low pH (2.0). <i>Lacticaseibacillus</i> sp. FS2 exhibited the greatest resistance (129.9 8%) to 1% bile salt, whereas <i>Levilactobacillus brevis</i> FL12 was the most sensitive (87.00%). However, all strains showed tolerance to pepsin (48.85-125.76%), pancreatin (56.14-169.01%), and phenol (54.16-113.24%) at various levels. The strains showed different levels of susceptibility to antibiotics. The antimicrobial activity of the strains against the test microorganisms exhibited considerable variability (8-30 mm). Although all strains showed viability at 1.5% NaCl, twelve strains survived at 10% NaCl. The proteolytic enzyme activity of the strains exhibited a range of 0.002 to 0.086 mg tyrosine/mL, whereas eight strains showed no β-galactosidase enzyme activity. Moreover, most of the strain showed high hydrophobicity towards xylene (16.39-94.43%), while auto-aggregation and co-aggregation abilities varied from 4.76 to 19.10% and 0.97 to 27.75%, respectively. In conclusion, the findings indicated that the strains exhibited high probiotic potential and could be employed as dietary supplements or as a starter culture for designing various functional food products.</p>","PeriodicalId":16004,"journal":{"name":"Journal of Food Science and Technology-mysore","volume":"62 9","pages":"1653-1666"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12304383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Developing novel synbiotic low-fat yogurt using sour cherry pomace pectin-derived oligosaccharides: <i>Lactobacillus acidophilus</i> survival, quality and antioxidant properties.","authors":"Karim Parastouei, Faramarz Khodaiyan, Seyed Saeid Hosseini","doi":"10.1007/s13197-024-06162-2","DOIUrl":"https://doi.org/10.1007/s13197-024-06162-2","url":null,"abstract":"<p><p>In this study, microwave-assisted extraction of pectin from sour cherry pomace was accomplished and the obtained supernatant was hydrolyzed by pectinase enzyme. Afterward, the pectin-derived oligosaccharides (POS) at different concentrations (0.1, 0.4, 0.8 and 1.2% w/v) as prebiotics along with <i>Lactobacillus acidophilus</i> bacteria as probiotics were used to produce low-fat synbiotic yogurts. The results showed that adding the POS up to 0.4% w/v led to a significant increase in acidity, viscosity and probiotics viability and a decrease in pH and syneresis. Also, the addition of these hydrolysates rich in antioxidants increased the antiradical activity of produced yogurts. In addition, the POS in low concentrations improved the sensory properties, while these features were reduced in presence of higher concentrations of hydrolysates. Generally, it can be stated that the sour cherry pectin hydrolysates at low concentrations could be used to develop a wonderful synbiotic yogurt with high organoleptic properties.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s13197-024-06162-2.</p>","PeriodicalId":16004,"journal":{"name":"Journal of Food Science and Technology-mysore","volume":"62 9","pages":"1782-1791"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12304337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Monitoring the changes in UHT whole milk during storage under dynamic and constant temperature profiles.","authors":"Recep Burak Zeren, Sencer Buzrul, Gonca Bilge","doi":"10.1007/s13197-024-06140-8","DOIUrl":"https://doi.org/10.1007/s13197-024-06140-8","url":null,"abstract":"<p><p>The objective of the study was to monitor some physical and chemical changes of UHT whole milk stored under constant and dynamic temperature. UHT milk samples were stored at constant room temperature (25 °C) and at constant abuse temperature (41.5 °C). Dynamic condition was attained by switching the samples between 25 and 41.5 °C with 24 h intervals up to 158 days. Physical and chemical analyses revealed that most dramatic changes obtained in samples stored at 41.5 °C followed by dynamic temperature and 25 °C. The changes in the samples stored dynamically were in between but closer to those of stored at 25 °C. The pH levels reduced, and acidity, electrical conductivity and viscosity increased at the end of the storage period (158 days). Brown color was apparent for the samples stored at 41.5 °C and samples stored dynamically had also darker color than that of the samples stored at 25 °C whereas color of freshly UHT processed milks was indistinguishable from the samples stored at 25 °C. Our results indicate that shelf life studies based on isothermal conditions should be reconsidered for UHT milk since it is almost impossible to attain constant temperature during shipment or storage.</p>","PeriodicalId":16004,"journal":{"name":"Journal of Food Science and Technology-mysore","volume":"62 9","pages":"1720-1727"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12304367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preparation of new modified pyrogallol vinyl monomer and its antimicrobial and antioxidant properties.","authors":"Sharifa Salma Sulistiawan, Kambiz Sadeghi, Yun-Je Choi, Chan-Moon Chung, Jongchul Seo","doi":"10.1007/s13197-025-06228-9","DOIUrl":"https://doi.org/10.1007/s13197-025-06228-9","url":null,"abstract":"<p><p>Biomaterials are widely applied. However, their application is limited as they cannot be processed using conventional industrial fabrication methods, such as extrusion, injection molding, or polymerization. Therefore, pyrogallol (PG), a functional biomaterial, was methacrylated using glycidyl methacrylate (GMA) through a simple ring-opening reaction. The introduction of GMA into the backbone of PG led to the synthesis of methacrylated pyrogallol (PGMC) vinyl monomers, which have high thermal stability, potent antimicrobial properties, and strong antioxidant activity. In addition, the chemical modification of PG led to the introduction of an additional reactive group (methacrylate group), making PGMC monomers processable for industrial purposes. Therefore, PGMC monomers can be used as strong bioactive agents for conventional heat-induced fabrication processes or for copolymerization with other monomers.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s13197-025-06228-9.</p>","PeriodicalId":16004,"journal":{"name":"Journal of Food Science and Technology-mysore","volume":"62 9","pages":"1792-1798"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12304388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}