农林科学最新文献

{"title":"Canine Maxillofacial Parosteal Osteosarcoma: A Retrospective Case Evaluation in 10 Dogs.","authors":"Geneva Kernaghan, Jessica Johnson, Randi Gold, Cynthia Bell","doi":"10.1177/08987564261440316","DOIUrl":"10.1177/08987564261440316","url":null,"abstract":"<p><p>Parosteal osteosarcoma (OSA) is a subtype of surface OSA that is considered slow growing with a less aggressive biological behavior compared to central OSA and, therefore, carries a better prognosis with surgical excision. Parosteal OSA has a predilection for the skull in dogs with documented more frequent occurrences on the zygoma, maxilla, or coronoid process of the mandible, all of which present unique challenges to the oral surgeon. Ten cases of parosteal OSA of the canine maxillofacial bones are summarized and discussed in this report. The most common bone of origin was the caudal maxilla and/or zygoma in 50% of tumors. Exophthalmos was a prominent clinical sign noted in 40% of dogs. Median survival time was 14 months, with a one-year survival rate of 60%. Metastasis to the lungs was suspected in three cases. The histopathological diagnosis of parosteal OSA is crucially dependent on diagnostic imaging. When a primary bone tumor of the maxillofacial bones is suspected, it is essential for the oral surgeon and pathologist to collaborate to provide informed guidance on surgical planning, anticipated long-term outcomes, and clinical monitoring for these patients. The goals of this retrospective study are to identify key clinical and radiographic features, improve recognition for accurate diagnosis, and establish treatment recommendations for canine maxillofacial parosteal OSA.</p>","PeriodicalId":17584,"journal":{"name":"Journal of Veterinary Dentistry","volume":" ","pages":"490-501"},"PeriodicalIF":0.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of Concern: \"Estimation of TiO2 nanoparticle-induced genotoxicity persistence and possible chronic gastritis-induction in mice\" [Food chem. Toxicol. 83 (2015) 76-83 10.1016/j.fct.2015.05.018].","authors":"","doi":"10.1016/j.fct.2026.116323","DOIUrl":"10.1016/j.fct.2026.116323","url":null,"abstract":"","PeriodicalId":317,"journal":{"name":"Food and Chemical Toxicology","volume":"217 ","pages":"116323"},"PeriodicalIF":3.2,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Production of Reactive Oxygen Species Induced by Peracetic Acid Enhances Bactericidal Activity and Mutagenesis in <i>Salmonella</i> Typhimurium.","authors":"Mohammed K W Al-Doury, Elena G Olson, Steven C Ricke, Michael J Rothrock, Young Min Kwon","doi":"10.1177/15353141251384160","DOIUrl":"10.1177/15353141251384160","url":null,"abstract":"<p><p>Peracetic acid (PAA) is extensively used in poultry processing, but its bactericidal mechanism remains poorly understood. Reactive oxygen species (ROS) are linked to bacterial cell death by many bactericidal agents. This study investigated the role of ROS in PAA against <i>Salmonella</i> Typhimurium 14028 using bacterial suspensions treated with PAA alone (20 ppm), PAA combined with 2,2'-dipyridyl (Dip; iron chelator) or with thiourea (ROS scavenger) followed by incubation at 37°C for 1 h. Post-incubation, serial dilutions were plated on Luria-Bertani agar to determine colony-forming units per milliliter. Additionally, eight single-deletion mutants and the wild-type (control) of <i>Salmonella</i> Typhimurium 14028 were tested for survivability after exposure to PAA (treatment; 20 ppm) and hydrogen peroxide (H₂O₂; control). The mutants were categorized by predicted ROS impact: increase in ROS production (<i>atpC</i>, <i>gnd</i>, <i>nuoG</i>, <i>pta, sdhC</i>, and <i>zwf</i>) and no change in ROS production (negative control; <i>edd</i> and <i>pykA</i>). Finally, rifampicin-based selection assay was utilized to evaluate the mutation rate of the wild-type strain in the presence of PAA (60 ppm), H₂O₂ (control), and PAA + thiourea. Treatment with 20 ppm PAA significantly (<i>p</i> < 0.05) reduced the viability of <i>Salmonella</i> Typhimurium 14028 by a log₁₀ reduction of 0.34, while co-treatment with thiourea restored counts to control level. The survival of the mutants predicted to increase ROS production was significantly reduced compared with the control mutants and wild-type strain (<i>p</i> < 0.05). Exposure to sublethal PAA led to a 28-fold increase in mutation rate suggesting the production of ROS by PAA was responsible for the observed increase. ROS production is a significant component of PAA's bactericidal activity against <i>Salmonella</i> Typhimurium, and increasing ROS production might be exploited to enhance PAA-mediated killing of <i>Salmonella</i> Typhimurium. ROS production by PAA can lead to the development of antibiotic resistance in <i>Salmonella</i> Typhimurium when cells manage to escape cell death.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":"755-762"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145185228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pilot Study of Gallic Acid Cream as a Potential Treatment for Plaque Psoriasis.","authors":"Robert R Greenway, Ann A Coulter, Dachuan Zhang, Frank L Greenway","doi":"10.1177/1096620X261458593","DOIUrl":"10.1177/1096620X261458593","url":null,"abstract":"<p><p>Gallic acid, a catechin polyphenol in tea, completely inhibited angiogenesis in assays of human tissue at 10^-3 M. Psoriasis is a skin disease caused by excessive secretion of angiogenenic factors by keratinocytes and stromal skin cells. In a double-blind pilot study, six subjects with bilateral plaque psoriasis were treated with 10^-2 M gallic acid in a cream base or with a cream base placebo over 8 weeks, four times a day, and treatments were randomly assigned to either the left or the right side. The gallic acid cream was well tolerated, but it did not reduce the psoriasis more than the placebo. One subject wanted to extend treatment for an additional 8 weeks. At the end of 16 weeks, the subject had complete resolution of the psoriatic plaque treated with gallic acid cream. In contrast, the plaque treated with placebo cream was not reduced and stayed equivalent to week six. Gallic acid is inexpensive and does not cause side effects. A longer trial evaluating 10^-2 M gallic acid cream for the treatment of psoriasis seems indicated.</p>","PeriodicalId":16440,"journal":{"name":"Journal of medicinal food","volume":" ","pages":"637-642"},"PeriodicalIF":1.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148199373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into the interaction mechanisms between mogrosides and sweet and bitter taste receptors obtained by integrating molecular docking and dynamics simulations.","authors":"Yuqi Qin, Huahong Liu, Yuxin Wu, Wenying Jin, Zhusheng Liu, Yuelan Pang, Xuehui Tang, Yun Zhang, Jinfang Nie","doi":"10.1002/jsfa.70879","DOIUrl":"10.1002/jsfa.70879","url":null,"abstract":"<p><strong>Background: </strong>Mogrosides are gaining popularity as alternatives to sucrose due to their high-intensity sweetness, low caloric content, and associated health benefits; however, the flavor mechanisms of different mogroside types remain poorly understood. To investigate this, molecular docking, molecular dynamics (MD) simulations, and steered molecular dynamics (SMD) simulations were conducted to explore the interactions of 12 mogrosides with taste receptor type 1 member 2-member 3 (T1R2-T1R3) and bitter taste receptors (T2Rs).</p><p><strong>Results: </strong>The docking results for T1R2-T1R3 suggested a strong correlation between docking scores and the sweetness intensity of mogrosides. Siamenoside I, iso-mogroside V, and mogroside V, among others, not only bound to the Venus flytrap-like domain (VFT) of T1R2-T1R3 but also interacted with the seven-transmembrane helix domain (TMD). The sweet mogrosides did not bind to T2Rs, and only two bitter mogrosides interacted with them. Molecular dynamics simulations confirmed the conformational stability of the receptor-ligand complexes obtained from docking. Steered molecular dynamics simulations demonstrated that sweeter mogrosides exhibited stronger binding and slower dissociation from T1R2-T1R3, whereas bitter mogrosides showed distinct binding strengths and durations across T2Rs (T2R46 > T2R14 > T2R4).</p><p><strong>Conclusion: </strong>Overall, these results indicate that the delayed sweetness onset, prolonged sweet aftertaste, and slight bitterness characteristic of mogrosides can be attributed to the indirect signaling role of the TMD of T1R2-T1R3, spatially restricted pocket, and interaction with T2Rs. This study advances knowledge of mogroside flavor mechanisms and provides a theoretical basis for their targeted modification. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":"8701-8712"},"PeriodicalIF":4.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148412205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and application of novel acetylated starch-chitosan-oregano essential oil active extrudates for meat product microbiological preservation.","authors":"Maury S Hernández, Leandro N Ludueña, Silvia K Flores","doi":"10.1002/jsfa.70877","DOIUrl":"10.1002/jsfa.70877","url":null,"abstract":"<p><strong>Background: </strong>Developing biodegradable active packaging with improved mechanical and antimicrobial properties remains a key challenge in food preservation. This study evaluated the physical and antimicrobial performance of extruded sheets based on a base mixture of acetylated tapioca starch, glycerol and water (BMAS), chitosan (CH) and oregano essential oil (OEO).</p><p><strong>Methods: </strong>Extruded sheets with varying BMAS, CH and OEO proportions were formulated using a simplex centroid mixture design. Mechanical properties, water solubility, color and thermal behavior were analyzed. Sheets antimicrobial activity was tested in contact with a chicken meat-based food against external contamination by Escherichia coli, Listeria innocua, Enterococcus faecium, or Zygosaccharomyces bailii.</p><p><strong>Results: </strong>Two optimal formulations (g kg^-1) were identified: central point (853.3 BMAS, 93.3 CH, 53.3 OEO) and S7 (840 BMAS, 80 CH, 80 OEO), both showing the highest stress at break (≈ 1.06 MPa), but maximum (105%) and minimal (26%) deformation, respectively. Water solubility was 40% for central point and 47% for S7. OEO increased mechanical resistance but reduced solubility compared to controls without oil. Acetylation improved tensile strength, solubility and whiteness, though slightly decreasing thermal stability. Regarding antimicrobial barrier action, the effectiveness was microorganism dependent: while Z. bailii was not detected along storage, Escherichia coli was more sensitive than L. innocua and Enterococcus faecium.</p><p><strong>Conclusion: </strong>The present findings indicate that the developed extrudates are promising candidates for biodegradable active food packaging. The retained availability of OEO effectively contributed to microbial spoilage control, with Z. bailii and Escherichia coli exhibiting greater susceptibility compared to L. innocua and Enterococcus faecium. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":"8604-8616"},"PeriodicalIF":4.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148397105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of pesticide residues in pears using the same phytosanitary treatments and grown under the same edaphoclimatic conditions.","authors":"Sílvia Cruz Barros, Patricia Cazón, João David Teixeira, Ana Rita Mateus, Martina Vitelli, Nicola Nicolini, Monica Rosa Loizzo, Claudia Sánchez, Miguel Leão de Sousa, Duarte Torres, Ana Sanches Silva","doi":"10.1002/jsfa.70863","DOIUrl":"10.1002/jsfa.70863","url":null,"abstract":"<p><strong>Background: </strong>The distribution of pesticide residues within fruit tissues is influenced by the physicochemical properties of the active substances and may vary among cultivars. Information on residue partitioning in different tissues of traditional pear cultivars remains limited. Therefore, this study evaluated the occurrence and distribution of pesticide residues in the peel, pulp, and seeds of six Portuguese regional pear cultivars and one commercial cultivar grown under identical edaphoclimatic conditions and subjected to the same phytosanitary treatments.</p><p><strong>Results: </strong>Pesticide residues in peel, pulp, and seeds were evaluated by a validated QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) liquid chromatographic-mass spectrometric method. The distribution of residues was closely correlated with the physicochemical characteristics of the active compounds. Highly lipophilic chemicals with poor systemic mobility, such as pyriproxyfen and triflumuron, were largely deposited in peel, whereas moderately systemic compounds including fluopyram, chlorantraniliprole and trifloxystrobin were also discovered in seeds. In most cultivars, the peel was the primary residue reservoir, contributing around 85% of total residues, followed by seeds at 13% and pulp at 1%. The most often found pesticide was difenoconazole, followed by indoxacarb and pyriproxyfen. Differences between cultivars indicated that specific fruit characteristics may be involved in residue partitioning and retention patterns.</p><p><strong>Conclusion: </strong>The distribution of pesticide residues in pears is influenced by the physicochemical properties of the pesticide and the cultivar-specific variables Residues were mainly found in the peel and to a lesser level in the seeds, and the pulp was found to be little contaminated or uncontaminated. These results contribute to a better knowledge of residue behavior in pear cultivars and may assist future risk assessment, monitoring tactics, and residue management practices. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":"8539-8553"},"PeriodicalIF":4.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biological Effects of Bovine Lactoferrin on Keratinocyte Proliferation and Migration (Bovine Lactoferrin and Wound Healing Response).","authors":"Morgana Lüdtke Azevedo, Laís Medeiros Cardoso, Caroline Anselmi, Rafael Guerra Lund","doi":"10.1177/1096620X261460635","DOIUrl":"10.1177/1096620X261460635","url":null,"abstract":"<p><p>Lactoferrin (Lf), an iron-binding glycoprotein present in various exocrine secretions, exhibits a wide range of biological activities, including cell proliferation, immune modulation, and antimicrobial effects. This study investigates the bioactivities of commercially available Lf derived from bovine milk. Commercial Lf, with a purity exceeding 95%, was analyzed using chemical and cell-based assays. Fourier-transform infrared spectroscopy confirmed the protein's identity through characteristic peaks. Cell viability assays demonstrated noncytotoxic effects, while cell morphology analysis and proliferation assays revealed that Lf stimulated human keratinocyte (HaCaT) proliferation in a concentration-dependent manner. Wound healing assays showed that Lf promotes wound closure, with optimal effects observed at lower concentrations. However, antimicrobial assays revealed that Lf alone did not exhibit activity against <i>Staphylococcus aureus</i> and <i>Pseudomonas aeruginosa</i>. These findings highlight the importance of purity and concentration in determining the biological activity of Lf. Further studies are warranted to investigate the molecular mechanisms underlying these effects and the potential applications of bovine Lf in therapeutic contexts.</p>","PeriodicalId":16440,"journal":{"name":"Journal of medicinal food","volume":" ","pages":"655-664"},"PeriodicalIF":1.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148277713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Closed Extraction of Deciduous Canine Teeth Required Less Surgical Time Without Increased Complication Rate Compared to an Open Technique in Dogs and Cats.","authors":"Cody Taylor Fielder, Brook A Niemiec","doi":"10.1177/08987564261428606","DOIUrl":"10.1177/08987564261428606","url":null,"abstract":"<p><p>The study was performed to compare surgical time and potential complications for closed versus open extraction technique of deciduous canine teeth in dogs and cats. The authors hypothesize that closed extractions can be accomplished with less time and surgical trauma without increasing the incidence of postoperative complications than open extractions of deciduous canine teeth. A search of electronic medical records identified 305 deciduous canine tooth extractions from June 1, 2019, to December 31, 2022, at a multi-location veterinary dental referral practice. Comparison groups included 237 closed and 68 open extractions. Records verified the extracted tooth, reason for extraction, type (closed or open), recheck, and complication history. Time was recorded for 61 closed and seven open procedures. Data were analyzed for significant correlations. Twenty teeth (6.6%) were extracted due to fracture exposing the pulp, 178 (58.4%) for persistent deciduous teeth, 71 (23.3%) for interceptive orthodontics to treat malocclusion, and 36 (11.8%) for retained tooth roots. Mean extraction times were 74.66 s (95% CI: 71.06-78.06) for closed and 349.9 s (95% CI: 148.8-551) for open. Rechecks were performed on 43/116 (37.07%) closed and 19/47 (40.43%) open extraction patients. No extraction site dehiscence was noted. Enamel hypoplasia was noted in 3/30 (10%) closed extractions. Closed procedures were completed in less than half the time compared to open extractions. Closed extraction eliminates the possibility of flap dehiscence and iatrogenic enamel hypoplasia incidence was lower than recently reported for open extraction of deciduous canine teeth. Results demonstrated that closed extractions of deciduous canine teeth can be efficiently and effectively performed, with multiple benefits to patients, pet owners, and practitioners compared with results of open extraction procedures.</p>","PeriodicalId":17584,"journal":{"name":"Journal of Veterinary Dentistry","volume":" ","pages":"437-445"},"PeriodicalIF":0.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147494218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Purple tea extract-modified chitosan films with pH-responsive properties for fresh shrimp freshness monitoring.","authors":"Jingfeng Xu, Pingxiong Cai, Yuanfeng Pan","doi":"10.1002/jsfa.70886","DOIUrl":"10.1002/jsfa.70886","url":null,"abstract":"<p><strong>Background: </strong>Faced with the relentless depletion of fossil fuels and the global environmental crisis, the strategic utilization of abundant biomass resources has drawn significant attention, offering vast application prospects in the field of food packaging. This study pioneers an investigation into the effects of incorporating purple tea extract (PTE) in chitosan (CS) films on their fundamental physical properties and functionalization, leading to an active and intelligent CS/PTE composite film with pH-responsive characteristics and improved physical properties.</p><p><strong>Results: </strong>X-ray diffraction and Fourier transform infrared analyses indicate that CS and PTE interact primarily through hydrogen bonding, demonstrating high compatibility. The impact of varying PTE concentrations on the water vapor permeability, transparency, mechanical properties, antioxidant activity, antimicrobial performance, and pH responsiveness of the CS film was systematically investigated. The experimental results show that PTE significantly enhances the films' light and water vapor barrier properties. Specifically, films containing more than 6% PTE exhibit improved antioxidant, antimicrobial, and food preservation capabilities. The resulting composite film demonstrated excellent antioxidant and antibacterial performance with a DPPH radical scavenging rate of 83.2%, and inhibitory rates exceeding 90% against Escherichia coli and Staphylococcus aureus, as well as pH-responsive color changes.</p><p><strong>Conclusion: </strong>Overall, the CS/PTE composite film represents a highly promising active and intelligent food packaging material. It not only expands the range of naturally available materials for smart packaging films but also holds significant potential for practical applications in the food industry. © 2026 Society of Chemical Industry.</p>","PeriodicalId":17725,"journal":{"name":"Journal of the Science of Food and Agriculture","volume":" ","pages":"8882-8893"},"PeriodicalIF":4.0,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}