Acta Medica Lituanica最新文献

{"title":"Embryological Basis and Genetic Considerations of Right Lumbar Undescended Caecum with Paracaecal Appendix and Aberrant Vascular Supply.","authors":"Anand Verma, Madhumita Patnaik, Praveen Kumar Ravi, Sayan Biswas, Manisha R Gaikwad, Aarthi Manokaran","doi":"10.15388/Amed.2026.33.1.23","DOIUrl":"10.15388/Amed.2026.33.1.23","url":null,"abstract":"<p><p>The caecum normally descends to the right iliac fossa during embryogenesis. Disruptions in midgut development may result in its atypical positioning. In a male cadaver, the small, conical caecum and paracaecal appendix were in the right lumbar region. The ileocaecal orifice was on the anterior caecal wall, and the appendicular orifice opened on the medial caecal wall inferior to it. The ascending colon was short, and the hepatic flexure was inferior to hepatic quadrate lobe. The right colic artery was absent. The ascending branch of the ileocolic artery supplied the caecum, and the appendix. The disposition of the rest of the intestinal tract and peritoneum were observed, and measurements were taken. Midgut development involves multiple regulatory genes, signalling pathways, transcription factors and mesenchyme-endoderm cross-talk. Mutations in several candidate genes were identified as contributing to midgut malrotation. Awareness of such a rare anatomical variation is essential to avoid misdiagnosis of atypical appendicitis or intestinal obstruction.</p>","PeriodicalId":34365,"journal":{"name":"Acta Medica Lituanica","volume":"33 1","pages":"245-251"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13479652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use of Virtual Reality for Pain and Anxiety Reduction: A Literature Review.","authors":"Gerda Marčiūtė, Ignas Lapeikis, Greta Kasputytė","doi":"10.15388/Amed.2026.33.1.2","DOIUrl":"https://doi.org/10.15388/Amed.2026.33.1.2","url":null,"abstract":"<p><p>Virtual reality (VR) is being increasingly used as an adjunctive tool to reduce procedural pain and anxiety during various interventional procedures. Forty articles published between 2020 and 2025 were reviewed. The articles reviewed discuss the use of virtual reality to reduce procedural pain and anxiety during various interventional procedures. The results of the literature analysis show that VR can effectively direct patients' attention and reduce the subjective intensity of pain and fear during procedures across different age groups. VR has been successfully applied to interventional procedures such as vaccination, blood draws, and peripheral vein punctures in children, as well as to a wide range of interventions in obstetrics, orthopaedics, endovascular surgery, cardiology, and dentistry. The studies reviewed confirm that VR is a safe method that rarely causes adverse side effects and can be integrated into clinical practice, contributing to patient comfort, emotional well-being, and the overall satisfaction with the procedure.</p>","PeriodicalId":34365,"journal":{"name":"Acta Medica Lituanica","volume":"33 1","pages":"23-32"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13479660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teenagers in Face of the War in Ukraine: Experience of Lithuanians.","authors":"Sigita Lesinskienė, Augustė Lapinskaitė, Augustė Česnauskaitė","doi":"10.15388/Amed.2026.33.1.9","DOIUrl":"https://doi.org/10.15388/Amed.2026.33.1.9","url":null,"abstract":"<p><strong>Background: </strong>The war in Ukraine, starting on February 24, 2022, shocked Lithuanians who actively support Ukraine and who are still experiencing the threat of an extended war. Adolescents are a sensitive group in society. They go through many changes at their age and are in the process of revealing their feelings and forming their worldviews. The study aimed to investigate how war events in Ukraine affected Lithuanian adolescents' everyday life, relationships, health, attitudes, concentration, and learning.</p><p><strong>Materials and methods: </strong>Adolescents in 6 high schools filled out an anonymous <i>Google Forms</i> survey developed by the authors comprising general data about the respondent, their interest in war events and their involvement in following the news about the war in media, the impact of war events on their physical and mental health, and the feeling of fear about the threats of the war in Lithuania.</p><p><strong>Results: </strong>395 adolescents aged 16-19 (mean age 17.01±0.97) filled in the questionnaire. This research revealed that adolescents in Lithuania are moderately interested in war events in Ukraine, and 25.3% noted that they follow news about the war once a week. Most teenagers did not note that the ongoing war in Ukraine would affect their communication, ability to concentrate and learn, hobbies, appetite, and sleep. However, 48.9% indicated that war events affected their emotions and mood. Adolescents who talked about the ongoing war with their parents (55.4%, <i>p</i>=0.00006), who were more interested in war events in the media (median=229.7, <i>p</i><0.001), and girls (53.3%, <i>p</i>=0.008) were statistically significantly more likely to notice that the ongoing war would affect their emotions and mood. 60.8% of the respondents felt fear and threat that war may break out in Lithuania as well.</p><p><strong>Conclusions: </strong>The news in the media and the constant threat of war affect Lithuanian youth, mostly their emotions and mood. Therefore, it is crucial to research and monitor their emotional health, discuss things with teenagers, and provide them with a possibility to share their views, thoughts, perceptions, fears, and feelings. Talking with youth about the war situation responsibly, promptly, and age appropriately is essential.</p>","PeriodicalId":34365,"journal":{"name":"Acta Medica Lituanica","volume":"33 1","pages":"116-127"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13479650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Pancreatitis Unmasking an Ectopic Parathyroid Adenoma in MEN1 Syndrome and Cushing's Syndrome: A Rare Clinical Convergence.","authors":"Asif Dabeer Jafri, Om Prakash Sanjeev, Aftab Hasan Nazar, Ratender Kumar Singh","doi":"10.15388/Amed.2026.33.1.22","DOIUrl":"https://doi.org/10.15388/Amed.2026.33.1.22","url":null,"abstract":"<p><p>Ectopic parathyroid adenoma within the spectrum of Multiple Endocrine Neoplasia Type 1 (MEN1) is an extremely rare clinical entity. We report a 27-year-old woman who presented with <i>acute pancreatitis</i> as the sentinel manifestation of MEN1, an atypical and intriguing clinical scenario. Initially, her serum calcium levels were deceptively normal, only to surge later, unmasking a deeper endocrine pathology. Subsequent biochemical evaluation established <i>primary hyperparathyroidism (PHPT)</i>, and a methoxyisobutylisonitrile (MIBI) scan revealed an ectopic parathyroid adenoma as the culprit lesion. Further endocrine profiling disclosed <i>Cushing's syndrome (CS)</i>, confirmed through a low-dose dexamethasone suppression test, while a positive family history of MEN1-related tumors in her sister solidified the syndromic diagnosis. She was treated with aggressive hydration, analgesia, antibiotics, and supportive therapy, followed by successful parathyroidectomy. This case illustrates a remarkable convergence of conditions including ectopic parathyroid adenoma, acute pancreatitis, and MEN1 with the additional complexity of initially normocalcemic presentation during the acute phase of pancreatitis. Although the pathophysiological link between hypercalcemia and pancreatitis remains debated, pancreatitis secondary to hypercalcemia from primary hyperparathyroidism is rare, and its presentation as the first clue to MEN1 is exceptionally uncommon. ACTH-secreting pituitary adenomas causing CS are also a rare manifestation of MEN1, and the concomitant presence of an empty sella on brain Magnetic resonance imaging (MRI) further underscores the uniqueness of this case. To the best of our knowledge, this represents the first documented instance in which acute pancreatitis with normocalcemia concealed an underlying ectopic parathyroid adenoma in MEN1, accompanied by CS and an empty sella, making this a noteworthy clinical and diagnostic rarity.</p>","PeriodicalId":34365,"journal":{"name":"Acta Medica Lituanica","volume":"33 1","pages":"238-244"},"PeriodicalIF":0.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13479657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Assessments of PET and ASL MR Perfusion in the Evaluation of Early Dementia.","authors":"Savyasachi Jain, Shailesh B Gaikwad, Bheru Dan Charan, Anu Gupta, Madhvi Tripathy","doi":"10.15388/Amed.2025.32.1.10","DOIUrl":"10.15388/Amed.2025.32.1.10","url":null,"abstract":"<p><strong>Background: </strong>Overtly morbid dementing diseases have a prodromal MCI (mild cognitive impairment) phase which is crucial to recognize. Clinical scores provide an easy bedside assessment tool for holistic cognitive evaluation but fail to provide lead time. While routine biomarkers of brain atrophy are late to appear, non-contrast MRI perfusion studies like ASL may serve as a valuable alternative to 18F-FDG-PET for the recognition and classification of the degree of neurodegeneration in individuals with MCI, especially when FDG-PET is not available. Our study adds confidence as we noted brain regions where PET-ASL concordance was most robust and devised concordance with ACE-3 scores.</p><p><strong>Material and methods: </strong>We conducted a prospective study from Jan 2021 to Jan 2024. Cases were selected based on the inclusion and exclusion criteria, which have objective cognitive impairment. Healthy controls were selected. MRI and PET scans were performed in all cases. Perfusion values of arterial spine labeling, PET, and clinical examination were recorded.</p><p><strong>Results: </strong>We included 33 patients and 15 healthy controls in the study. We compared ASL and PET for all selected individuals. Our study showed that ASL can detect a hypo-perfusion region with a 91% sensitivity, 85.98% specificity, 89.8% PPV, and 87.62% NPV, with a diagnostic accuracy of 88.9%.</p><p><strong>Conclusion: </strong>ASL was a dependable replacement for the gold-standard FDG-PET. ASL may serve as a valuable alternative to ¹⁸F-FDG-PET for classifying the degree of neurodegeneration in individuals with prodromal AD, especially when FDG-PET is unavailable.</p>","PeriodicalId":34365,"journal":{"name":"Acta Medica Lituanica","volume":"32 1","pages":"92-107"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239189/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mid-Cavitary Obstruction in Hypertrophic Cardiomyopathy (HCM): A Rare Case Report and Management Approach.","authors":"Rajeev Bharadwaj, Deb Boruah, Bhupen Barman, Suman Kalita","doi":"10.15388/Amed.2025.32.1.16","DOIUrl":"10.15388/Amed.2025.32.1.16","url":null,"abstract":"<p><p>Hypertrophic cardiomyopathy (HCM) with mid-cavitary obstruction (MCO) is an uncommon condition affecting approximately 10% of HCM patients which is associated with serious outcomes, including sudden cardiac death and heart failure. We present the case of a 43-year-old male with type 2 diabetes mellitus who experienced worsening dyspnea and palpitations, leading to the diagnosis of HCM with MCO without outlet obstruction. Cardiac MRI with gadolinium contrast reveals significant mid-cavitary obstruction without left ventricular outflow tract obstruction with a scar burden of 27% and the absence of other high-risk factors such as apical aneurysm and NSVT runs on Holter monitoring. The patient was treated conservatively with the oral beta-blocker therapy, resulting in symptomatic improvement. Given the high risk of an adverse outcome, it is crucial to recognise MCO early and provide the appropriate treatment. This case report discusses the presentation, diagnosis, and management of a patient with HCM and mid-cavitary obstruction, highlighting the unique treatment considerations associated with this condition.</p><p><strong>Take home message: </strong>Mid-cavitary obstruction (MCO) in hypertrophic cardiomyopathy (HCM) is associated with high-risk outcomes of sudden cardiac death and heart failure.While beta-blockers can improve symptoms in many MCO patients, treatment should be personalized based on the symptom severity and risk factors.Patients with MCO are at risk of complications like apical aneurysms, thromboembolism, and arrhythmias.</p>","PeriodicalId":34365,"journal":{"name":"Acta Medica Lituanica","volume":"32 1","pages":"138-144"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kaposi Varicelliform Eruption Complicated by Steroids: A Case Report and Review of Literature.","authors":"Aniket Goswami, Shikha Verma, Chingshubam Bikash, Pranjal Kalita","doi":"10.15388/Amed.2025.32.2.4","DOIUrl":"10.15388/Amed.2025.32.2.4","url":null,"abstract":"<p><p>Kaposi varicelliform eruption (KVE) is a severe disseminated cutaneous infection mainly caused by herpes simplex virus (HSV-1 or HSV-2). Herein, we report a case of KVE which was misdiagnosed elsewhere as a case of toxic epidermal necrolysis and received systemic steroids, following which, the patient's condition deteriorated. After being diagnosed as a case of KVE with the aid of tzanck smear, the patient was initiated on acyclovir and responded dramatically to the treatment. This case underscores the critical value of simple bedside tests, such as the tzanck smear, for rapid diagnosis of KVE and the timely initiation of treatment, facilitating prompt recovery. Additionally, it highlights the importance of histopathological evaluation in ambiguous cases so that to prevent mismanagement and ensure accurate diagnosis and the appropriate care.</p>","PeriodicalId":34365,"journal":{"name":"Acta Medica Lituanica","volume":"32 2","pages":"348-355"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12875543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cocaine-Induced Posterior Reversible Encephalopathy Syndrome (PRES): A Case Report Highlighting Neurological and Clinical Outcomes.","authors":"Patricija Griškaitė, Eleonora Kvaščevičienė, Gabija Laubner Sakalauskienė","doi":"10.15388/Amed.2025.32.1.20","DOIUrl":"10.15388/Amed.2025.32.1.20","url":null,"abstract":"<p><strong>Background: </strong>Posterior reversible encephalopathy syndrome (PRES) is a rare neurological condition characterized by disrupted cerebral autoregulation, often associated with clinical features such as hypertension, encephalopathy, seizures, and visual disturbances. Although it primarily affects females aged 20-65, posterior reversible encephalopathy syndrome can present across diverse demographics. This case underscores the critical importance of identifying uncommon risk factors to facilitate early diagnosis and optimal management.</p><p><strong>Clinical case: </strong>A 37-year-old male with stage 3 chronic kidney disease secondary to hereditary nephropathy and a history of cocaine and alcohol misuse presented to the emergency department with recurrent seizures, hypertension, hyperthermia and altered consciousness. Imaging demonstrated cortical-subcortical hypodensities on CT and parieto-occipital FLAIR hyperintensities on MRI, consistent with the diagnosis of PRES. A diagnosis of PRES was confirmed based on the patient's history, neurological evaluation, and characteristic radiological findings.</p><p><strong>Conclusions: </strong>Raising awareness of PRES and its less recognized but increasingly relevant risk factors, such as stimulant drug use - particularly cocaine - remains a critical aspect of improving diagnostic accuracy and management. Although PRES is typically reversible, delayed diagnosis and treatment may lead to permanent neurological complications, including cerebral infarction and hemorrhage.</p>","PeriodicalId":34365,"journal":{"name":"Acta Medica Lituanica","volume":"32 1","pages":"173-181"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatal Outcome of Suicidal Multi-Substance Ingestion Involving Sodium Nitrate and Nitrite Toxicity: A Case Report and Literature Review.","authors":"Sofija Saulė Kaubrytė, Sigitas Chmieliauskas, Giedrė Salyklytė, Sigitas Laima, Diana Vasiljevaitė, Jurgita Stasiūnienė, Paulius Petreikis, Robertas Badaras","doi":"10.15388/Amed.2025.32.1.11","DOIUrl":"10.15388/Amed.2025.32.1.11","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Nitrate and nitrite toxicity, particularly from sodium nitrite and sodium nitrate ingestion, has become a critical public health issue due to its role in accidental poisoning, foodborne exposure, and intentional self-harm. Sodium nitrite, commonly used in food preservation, is increasingly linked to suicide, with online resources providing accessible information on lethal dosages. This trend underscores an urgent need for regulatory action and preventive strategies. This report details a fatal case of nitrate and nitrite toxicity in a 19-year-old female, presenting a complex toxicological profile involving ethyl alcohol, amphetamines, and additional pharmaceuticals.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;A systematic literature search was conducted across &lt;i&gt;PubMed&lt;/i&gt; and &lt;i&gt;Google Scholar&lt;/i&gt; databases, spanning articles published over a period of the last 10 years, utilizing keywords relevant to the topic under consideration and their combinations. 58 pertinent articles were selected, supplemented by data from the &lt;i&gt;Lithuanian State Forensic Medicine Service&lt;/i&gt;, involving a clinical case. Autopsy findings, toxicological analyses, and contextual details were meticulously examined to elucidate the mechanism and circumstances of death.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Case presentation: &lt;/strong&gt;A 19-year-old female was found deceased in her home, alongside a suicide note indicating intent to self-harm through ingestion of sodium nitrate, sodium nitrite, and multiple medications. The autopsy findings included cherry-brown lividity, dark, non-coagulated blood within the heart chambers, and significant multi-organ congestion, consistent with methemoglobinemia and systemic hypoxia. Toxicology results confirmed a blood alcohol concentration of 1.22‰, with trace levels of amphetamine, atropine, and quetiapine, while nitrites detected in the gastric contents confirmed sodium nitrite as a primary toxic agent. The toxic synergy of these substances ultimately led to fatal multi-organ compromise.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;This case emphasizes the serious risks associated with nitrate and nitrite ingestion, particularly in instances of intentional overdose facilitated by readily accessible online information on lethal dosages. The autopsy findings reveal characteristic signs of methemoglobinemia and systemic hypoxia; however, a thorough forensic assessment must also consider additional factors, including the presence of a suicide note, the scene context, and any substances collected at the location.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Lessons: &lt;/strong&gt;Due to the inherent instability of nitrite in blood, its post-mortem detection is often challenging, thereby complicating toxicological confirmation. The increasing accessibility and misuse of sodium nitrite underscore an urgent need for regulatory oversight, public awareness, and enhanced preventive measures to address the rising incidence of intentional sodium nitrite toxicity, particularly within","PeriodicalId":34365,"journal":{"name":"Acta Medica Lituanica","volume":"32 1","pages":"160-172"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rescue Strategy in Cardiogenic Shock: Emergency Transcatheter Aortic Valve Implantation for Failed Bioprosthetic Valve - Case Report.","authors":"Ricardas Kundelis, Vilhelmas Bajoras, Sigitas Čėsna, Giedrius Davidavičius","doi":"10.15388/Amed.2025.32.1.1","DOIUrl":"10.15388/Amed.2025.32.1.1","url":null,"abstract":"<p><strong>Background: </strong><i>Transcatheter aortic valve implantation</i> (TAVI) has emerged as an essential therapeutic intervention for patients with severe aortic valve disease, providing a less invasive alternative to traditional surgery, particularly in high-risk individuals. TAVI is also increasingly utilized as a valve-in-valve strategy in cases of a bioprosthetic valve failure. However, data on the efficacy of TAVI in the context of a hemodynamic collapse remain limited.</p><p><strong>Methods: </strong>This report represents a young, high-risk patient with a failed bioprosthetic valve and cardiogenic shock treated successfully with TAVI.</p><p><strong>Results: </strong>Emergency TAVI using a <i>Medtronic Evolut Pro+</i> device achieved rapid hemodynamic stabilization and favorable post-procedural clinical and functional outcomes. Intermittent complete atrioventricular block necessitated the implantation of a permanent pacemaker.</p><p><strong>Conclusions: </strong>This case highlights the potential of TAVI as a safe and effective intervention in critical clinical scenarios. Emergency TAVI is a viable therapeutic intervention for patients with failed surgical bioprostheses presenting with cardiogenic shock.</p>","PeriodicalId":34365,"journal":{"name":"Acta Medica Lituanica","volume":"32 1","pages":"126-131"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}