Journal of Movement Disorders最新文献

Spatiotemporal Gait Parameters During Turning and Imbalance in Parkinson's Disease: Video-Based Analysis from a Single Camera.

IF 2.5 4区医学

Journal of Movement Disorders Pub Date : 2024-12-23 DOI: 10.14802/jmd.24210

HoYoung Jeon, Jung Hwan Shin, Ri Yu, Min Kyung Kang, Seungmin Lee, Seoyeon Kim, Bora Jin, Kyung Ah Woo, Han-Joon Kim, Beomseok Jeon

{"title":"Spatiotemporal Gait Parameters During Turning and Imbalance in Parkinson's Disease: Video-Based Analysis from a Single Camera.","authors":"HoYoung Jeon, Jung Hwan Shin, Ri Yu, Min Kyung Kang, Seungmin Lee, Seoyeon Kim, Bora Jin, Kyung Ah Woo, Han-Joon Kim, Beomseok Jeon","doi":"10.14802/jmd.24210","DOIUrl":"https://doi.org/10.14802/jmd.24210","url":null,"abstract":"Objectives: This study aims to objectively evaluate turning gait parameters in Parkinson disease (PD) patients using 2D-RGB video-based analysis and explore their relationships with imbalance.Methods: We prospectively enrolled PD patients for clinical assessments, balance analysis and gait with 180' turning. Spatiotemporal gait parameters during turning were derived based on video-based analysis and correlated with modified Hoehn and Yahr (mHY) stages and center of pressure (COP) oscillations.Results: A total of 64 PD patients were enrolled. The PD patients with higher mHY stages (≥2.5) had significantly longer turning times, higher number of steps, wider step bases and showed less variability in step length during turns. COP oscillations were positively correlated with mean turning time in the both anterio-posterior (AP) and right-left (RL) axis.Conclusions: Spatiotemporal gait parameters during turning, derived from video-based gait analysis, may be a promising biomarker for monitoring postural instability in PD patients.","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-motor fluctuations in Parkinson's disease: underdiagnosed, yet important. 帕金森病的非运动性波动：诊断不足，但很重要。

IF 2.5 4区医学

Journal of Movement Disorders Pub Date : 2024-12-20 DOI: 10.14802/jmd.24227

Iro Boura, Karolina Poplawska-Domaszewicz, Cleanthe Spanaki, Rosabel Chen, Daniele Urso, Riaan van Coller, Alexander Storch, Kallol Ray Chaudhuri

{"title":"Non-motor fluctuations in Parkinson's disease: underdiagnosed, yet important.","authors":"Iro Boura, Karolina Poplawska-Domaszewicz, Cleanthe Spanaki, Rosabel Chen, Daniele Urso, Riaan van Coller, Alexander Storch, Kallol Ray Chaudhuri","doi":"10.14802/jmd.24227","DOIUrl":"https://doi.org/10.14802/jmd.24227","url":null,"abstract":"Non-motor fluctuations (NMF) in Parkinson's disease (PD) significantly affect patients' well-being. Despite being identified over two decades ago, NMF remain largely under-recognized, under-treated, and poorly understood. While they are often temporally associated with motor fluctuations (MF) and can share common risk factors and pathophysiologic mechanisms, NMF and MF are currently considered distinct entities. The prevalence and severity of NMF, often categorized into neuropsychiatric, sensory, and autonomic subtypes, vary significantly across studies due to the heterogeneous PD populations screened and the diverse evaluation tools applied. The consistent negative impact of NMF on PD patients' quality of life (QoL) underscores the importance of further investigation via focused and controlled studies, validated assessment instruments and novel digital technologies. High-quality research is essential to illuminate the complex pathophysiology and clinical nuances of NMF, ultimately enhancing clinicians' diagnostic and treatment options in routine clinical practice.","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142864470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Muscle Dystonia Manifesting as Unilateral Rectus Abdominis Hypertrophy and Abdominal Pain in Parkinson's Disease: A Case Report.

IF 2.5 4区医学

Journal of Movement Disorders Pub Date : 2024-12-10 DOI: 10.14802/jmd.24230

Chengjian Wu, Yanhui Meng, Ming Yang

引用次数: 0

Video-oculography for enhancing the diagnostic accuracy of early oculomotor dysfunction in Progressive Supranuclear Palsy.

IF 2.5 4区医学

Journal of Movement Disorders Pub Date : 2024-12-09 DOI: 10.14802/jmd.24171

Harshad Chovatiya, Kanchana Pillai, Chakradhar Reddy, Amiya Thalakkattu, Ayana Avarachan, Manas Chacko, Asha Kishore

{"title":"Video-oculography for enhancing the diagnostic accuracy of early oculomotor dysfunction in Progressive Supranuclear Palsy.","authors":"Harshad Chovatiya, Kanchana Pillai, Chakradhar Reddy, Amiya Thalakkattu, Ayana Avarachan, Manas Chacko, Asha Kishore","doi":"10.14802/jmd.24171","DOIUrl":"https://doi.org/10.14802/jmd.24171","url":null,"abstract":"Background: Oculomotor impairment is an important diagnostic feature of Progressive Supranuclear Palsy (PSP) and PSP subtypes.Objectives: We assessed the role of video oculography (VOG) in confirming clinically suspected slow saccades in PSP and differentiating PSP from Parkinson's disease (PD). We also measured the correlation of both saccadic velocity and latency in PSP with scores in PSP rating scale, Montreal Cognitive Assessment (MoCA) and Frontal assessment battery (FAB). We assessed the frequency of apraxia of eyelid opening (ALO) and reflex blepharospasm in PSP and PD.Method: 112 PSP cases with slow saccades but not gaze palsy, 50 PD and 50 healthy controls (HC) were recruited. MDS task force-PSP and PD criteria were used respectively, for the diagnoses. All subjects underwent VOG.Result: Horizontal and vertical saccadic velocities and latencies differentiated PSP from PD and HC (p<0.001). Vertical saccadic velocity and latency accurately differentiated PSP-P from PD (p<0.001 and 0.003 respectively). Vertical and horizontal saccadic velocities differentiated PSP- RS and PSP- P (p=0.026 and 0.036 respectively). In vertical gaze, the mean velocity cut-off showed good sensitivity and specificity in differentiating PSP from HC and PD. Prolonged horizontal gaze latency was associated with more severe PSP and worse global cognitive and frontal dysfunction. ALO and reflex blepharospasm were only seen in PSP.Conclusion: VOG is useful for confirming slow saccades in PSP-RS and PSP-P and in differentiating PSP-P from PD. Prolonged horizontal gaze latency was associated with more severe PSP and worse cognitive dysfunction. ALO and reflex blepharospasm were seen only in PSP.","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complete relief of tardive truncal dystonia with a low dose of levodopa/carbidopa: A case report.

IF 2.5 4区医学

Journal of Movement Disorders Pub Date : 2024-12-09 DOI: 10.14802/jmd.24231

Shinichi Matsumoto, Satoshi Goto

引用次数: 0

The eye movement and gait variability analysis in Chinese patients with Huntington's disease.

IF 2.5 4区医学

Journal of Movement Disorders Pub Date : 2024-12-09 DOI: 10.14802/jmd.24151

Shu-Xia Qian, Yu-Feng Bao, Xiao-Yan Li, Yi Dong, Zhi-Ying Wu

{"title":"The eye movement and gait variability analysis in Chinese patients with Huntington's disease.","authors":"Shu-Xia Qian, Yu-Feng Bao, Xiao-Yan Li, Yi Dong, Zhi-Ying Wu","doi":"10.14802/jmd.24151","DOIUrl":"https://doi.org/10.14802/jmd.24151","url":null,"abstract":"Background: Huntington's disease disease (HD) is characterized by motor, cognitive, and neuropsychiatric symptoms. Oculomotor impairments and gait variability have been independently considered as potential markers in HD. But there lacks an integration analysis of eye movement and gait.Objective: We assessed multiple examinations of eye movement and gait variability in HTT mutation carriers, analyzed the consistency between these parameters and clinical severity, then examined the association between oculomotor impairments and gait deficits.Methods: Seven pre-HD, 30 HD patients and 30 age-matched controls were included. We collected demographics and assessed the Unified Huntington's Disease Rating Scale (UHDRS). Examinations including saccade, smooth pursuit and optokinetic (OPK) test were performed to evaluate eye movement function. The parameters of gait include stride length, walking velocity, step deviation, step length and gait phase.Results: There are significant impairments in HD patients in the latency and velocity of saccades, the gain of smooth pursuit as well as the gain and slow phase velocities (SPV) of OPK tests. Only the speed of saccades has significant difference between pre-HD and controls. There are significant impairments of stride length, walking velocity, step length and gait phase in HD patients. Parameters of eye movement and gait variability in HD patients showed consistency with the scores of UHDRS. There were significant correlations between eye movement and gait parameters.Conclusions: Our results show that eye movement and gait are impaired in HD patients, and speed of saccades is early impaired in pre-HD. Eye movement and gait abnormalities in HD are significantly correlated with clinical disease severities.","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Barriers to Accessing Deep Brain Stimulation for Parkinson's Disease Patients in Morocco.

IF 2.5 4区医学

Journal of Movement Disorders Pub Date : 2024-12-09 DOI: 10.14802/jmd.24225

Mohamed Daghi, Abdelhakim Lakhdar, Hicham El Otmani

引用次数: 0

The application of Deep Brain Stimulation in The Syndrome of Irreversible Lithium Effectuated Neurotoxicity.

IF 2.5 4区医学

Journal of Movement Disorders Pub Date : 2024-12-02 DOI: 10.14802/jmd.24209

Lina Okar, Peyton Murin, Anagha Prabhune, Richard Bucholz, Pratap Chand

引用次数: 0

Evidence-Based Review on Symptomatic Management of Huntington's Disease.

IF 2.5 4区医学

Journal of Movement Disorders Pub Date : 2024-12-02 DOI: 10.14802/jmd.24140e

Jung Hwan Shin, Hui-Jun Yang, Jong Hyun Ahn, Sungyang Jo, Seok Jong Chung, Jee-Young Lee, Hyun Sook Kim, Manho Kim

引用次数: 0

Gait parameters in Healthy Older Adults in Korea. 韩国健康老年人的步态参数。

IF 2.5 4区医学

Journal of Movement Disorders Pub Date : 2024-11-25 DOI: 10.14802/jmd.24181

Han-Kyeol Kim, Sung-Woo Kim, Jin Yong Hong, Min Seok Baek

{"title":"Gait parameters in Healthy Older Adults in Korea.","authors":"Han-Kyeol Kim, Sung-Woo Kim, Jin Yong Hong, Min Seok Baek","doi":"10.14802/jmd.24181","DOIUrl":"https://doi.org/10.14802/jmd.24181","url":null,"abstract":"Objective: Gait is the most fundamental and common form of human locomotion, essential in daily activities. We aimed to investigate gait parameters in medically and cognitively healthy older adults to determine the independent effects of age, physical attributes, and cognition on these parameters.Methods: This retrospective study enrolled healthy older adult participants aged ≥50 years with normal cognition and no neurological symptoms or medical/surgical histories that could potentially affect gait. Quantitative gait analysis was conducted using the GAITRite Electronic Walkway, categorizing gait parameters into spatiotemporal, spatial, temporal, phase, and variability. Gait parameters were compared between sexes across different age groups. The independent effects of age, Mini-Mental State Examination scores, and physical characteristics were analyzed using a multiple regression model.Results: This study included 184 participants with an average age of 72.2 years. After adjusting for age, height, and footwear, only the base width and its variability differed between the sexes. Gait parameters varied significantly among different age groups, revealing multiple inter-parameter associations. Age was independently correlated with decreased velocity, step and stride lengths, and single support time percentage and increased double support time, double support time percentage, and variability parameters, excluding the coefficient of variance of base width. Height was positively correlated with velocity, step and stride lengths, and base width, whereas leg length was negatively associated with cadence and positively associated with temporal parameters of gait.Conclusions: Gait parameters in healthy older adults were not only associated with age and physical characteristics, but also had inter-parameter correlations.","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0