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Journal of Movement Disorders最新文献

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Deep Brain Stimulation for Hemiballismus: A Case Report and Review of the Literature. 脑深部电刺激治疗偏瘫1例报告及文献复习。
IF 2.8 4区 医学
Journal of Movement Disorders Pub Date : 2025-10-01 DOI: 10.14802/jmd.25236
Negin Negin, Seyedehnarges Tabatabaee, Mansour Parvaresh-Rizi, Gholamali Shahidi, Behnam Safarpour Lima, Sadra Rohani, Renato P Munhoz, Alfonso Fasano, Mohammad Rohani
{"title":"Deep Brain Stimulation for Hemiballismus: A Case Report and Review of the Literature.","authors":"Negin Negin, Seyedehnarges Tabatabaee, Mansour Parvaresh-Rizi, Gholamali Shahidi, Behnam Safarpour Lima, Sadra Rohani, Renato P Munhoz, Alfonso Fasano, Mohammad Rohani","doi":"10.14802/jmd.25236","DOIUrl":"https://doi.org/10.14802/jmd.25236","url":null,"abstract":"","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Typical freezing of gait episodes reported as astasia-abasia in the 19th century. 典型的步态冻结发作报告为失稳-失稳在19世纪。
IF 2.8 4区 医学
Journal of Movement Disorders Pub Date : 2025-09-30 DOI: 10.14802/jmd.25214
Yasuyuki Okuma, Jorik Nonnekes, Bastiaan R Bloem
{"title":"Typical freezing of gait episodes reported as astasia-abasia in the 19th century.","authors":"Yasuyuki Okuma, Jorik Nonnekes, Bastiaan R Bloem","doi":"10.14802/jmd.25214","DOIUrl":"https://doi.org/10.14802/jmd.25214","url":null,"abstract":"","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conceptualizing a Personalized Care Pathway for Parkinson's Disease Using Wearable Sensors in Muslim Patients: The Ramadan Regimen. 在穆斯林患者中使用可穿戴传感器概念化帕金森病的个性化护理途径：斋月方案。
IF 2.8 4区 医学
Journal of Movement Disorders Pub Date : 2025-09-30 DOI: 10.14802/jmd.25198
Vinod Metta, Huzaifa Ibrahim, Haidar Dafsari, Rajinder K Dhamija, Hani T S Benamer, Tom Loney, Mishal Abu Al-Melh, Hasna Hussain, Afsal Nalarekttil, Guy Chung-Faye, Gloria Tanjung, Bushra Alblooshi, Shaikha Almazrouei, Bassam Darwish, Mohamed Al Mheiri, Mohamed Elmahdy, Rukmini Mridula, Sai Sampath Kumar, Vinay Goyal, Karolina Popławska-Domaszewicz, Cristian Falup Pecurariu, Prashanth Kukle, Jacob Chacko, Rupam Borgohain, Ray Chaudhuri
{"title":"Conceptualizing a Personalized Care Pathway for Parkinson's Disease Using Wearable Sensors in Muslim Patients: The Ramadan Regimen.","authors":"Vinod Metta, Huzaifa Ibrahim, Haidar Dafsari, Rajinder K Dhamija, Hani T S Benamer, Tom Loney, Mishal Abu Al-Melh, Hasna Hussain, Afsal Nalarekttil, Guy Chung-Faye, Gloria Tanjung, Bushra Alblooshi, Shaikha Almazrouei, Bassam Darwish, Mohamed Al Mheiri, Mohamed Elmahdy, Rukmini Mridula, Sai Sampath Kumar, Vinay Goyal, Karolina Popławska-Domaszewicz, Cristian Falup Pecurariu, Prashanth Kukle, Jacob Chacko, Rupam Borgohain, Ray Chaudhuri","doi":"10.14802/jmd.25198","DOIUrl":"https://doi.org/10.14802/jmd.25198","url":null,"abstract":"<p><p>Parkinson's disease (PD) affects approximately 2% of individuals over the age of 60. With over two billion Muslims observing Ramadan, individuals with PD encounter specific challenges, such as deteriorating motor skills, sleep disturbances, and an increased risk of falls during fasting. Our study focused on 75 patients with idiopathic PD divided into two groups: the Ramadan Regimen group, consisting of 50 patients who adjusted their medication to twice daily at Suhoor and Iftar, and the Non-Treatment group, which included 25 patients who abstained from medication for religious reasons. Both groups were instructed to wear a Parkinson's Kinetigraph (PKG) wrist device. Study findings showed that motor function worsened in the non-treatment group (p < .001), while it improved in the Ramadan Regimen group (p = .007). Daytime sleepiness also significantly increased in the non-treatment group (p < .001). Overall, findings suggest that Ramadan regime significantly enhance patient health and quality of life.</p>","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differential Peripheral NLRP3 Inflammasome Expression in Parkinson's Disease and Multiple System Atrophy. NLRP3炎性体在帕金森病和多系统萎缩中的差异表达。
IF 2.8 4区 医学
Journal of Movement Disorders Pub Date : 2025-09-30 DOI: 10.14802/jmd.25124
Jeongjae Lee, Han-Joon Kim, Huu Dat Nguyen, Suk Jun Song, Trung Nguyen Thanh, In Hee Kwak, Hye Joung Choi, Hyeo-Il Ma, Young Eun Kim
{"title":"Differential Peripheral NLRP3 Inflammasome Expression in Parkinson's Disease and Multiple System Atrophy.","authors":"Jeongjae Lee, Han-Joon Kim, Huu Dat Nguyen, Suk Jun Song, Trung Nguyen Thanh, In Hee Kwak, Hye Joung Choi, Hyeo-Il Ma, Young Eun Kim","doi":"10.14802/jmd.25124","DOIUrl":"https://doi.org/10.14802/jmd.25124","url":null,"abstract":"<p><strong>Objective: </strong>The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome has been proposed as a downstream mediator of neuroinflammation in Parkinson's disease (PD). However, its involvement across disease stages and related synucleinopathies such as multiple system atrophy (MSA) remains unclear. We aimed to analyze peripheral mRNA expression of NLRP3-related genes and cytokines across isolated REM sleep behavior disorder (iRBD), early and late-stage PD, and MSA.</p><p><strong>Methods: </strong>Peripheral blood mononuclear cells (PBMCs) were collected from 151 participants: 35 healthy controls (HCs), 31 iRBD, 41 early PD, 21 late PD, and 23 MSA. mRNA expression was measured using quantitative real-time polymerase chain reaction (qPCR). Statistical comparisons were performed using ANOVA or Welch's ANOVA, and associations with clinical variables were analyzed through stepwise multiple linear regression.</p><p><strong>Results: </strong>NLRP3 expression was significantly reduced in iRBD (p = 0.0263) and early PD (p = 0.0101) compared to HCs. NIMA-related kinase 7 (NEK7) showed a progressive decrease (HCs vs. early PD, p = 0.0008; vs. late PD, p < 0.0001). In contrast, apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) and caspase-1 were elevated in PD, especially in late stages. MSA resembled HCs but differed from PD. Interleukin (IL)-1β and IL-18 levels were not significantly different. In early PD, NLRP3 expression negatively correlated with disease duration, MDS-UPDRS Part II, and cognitive scores.</p><p><strong>Conclusion: </strong>Our findings challenge the prevailing hypothesis that NLRP3 inflammasome activation directly contributes to PD pathogenesis. Instead, the observed increase in ASC and caspase-1 expression suggests the potential involvement of alternative inflammasome pathways during disease progression.</p>","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Possible contribution of parietal lobe dysfunction to hand-foot synkinesis in corticobasal syndrome: A case report. 皮质基底综合征中顶叶功能障碍对手足联动性的可能贡献：1例报告。
IF 2.8 4区 医学
Journal of Movement Disorders Pub Date : 2025-09-19 DOI: 10.14802/jmd.25206
Gohei Yamada, Kenji Okita, Tomoyuki Kuno, Eiichi Katada
{"title":"Possible contribution of parietal lobe dysfunction to hand-foot synkinesis in corticobasal syndrome: A case report.","authors":"Gohei Yamada, Kenji Okita, Tomoyuki Kuno, Eiichi Katada","doi":"10.14802/jmd.25206","DOIUrl":"https://doi.org/10.14802/jmd.25206","url":null,"abstract":"","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145085178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Landscape of Parkinson's Disease Treatment in India: A National Cross-Sectional Survey of Clinical Practitioners. 帕金森氏病治疗在印度的景观：临床从业人员的全国横断面调查。
IF 2.8 4区 医学
Journal of Movement Disorders Pub Date : 2025-09-11 DOI: 10.14802/jmd.25201
Roopa Rajan, Hrishikesh Kumar, Divya M Radhakrishnan, Divyani Garg, Shreyashi Jha, Jacky Ganguly, Sreenivas U M, Niraj Kumar, Vikram V Holla, Soaham Desai, Ravi Yadav, Achal Kumar Srivastava, Asha Kishore, Pramod Kumar Pal
{"title":"The Landscape of Parkinson's Disease Treatment in India: A National Cross-Sectional Survey of Clinical Practitioners.","authors":"Roopa Rajan, Hrishikesh Kumar, Divya M Radhakrishnan, Divyani Garg, Shreyashi Jha, Jacky Ganguly, Sreenivas U M, Niraj Kumar, Vikram V Holla, Soaham Desai, Ravi Yadav, Achal Kumar Srivastava, Asha Kishore, Pramod Kumar Pal","doi":"10.14802/jmd.25201","DOIUrl":"https://doi.org/10.14802/jmd.25201","url":null,"abstract":"","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enriching global perspectives through a regional lens: Recognition, Assessment, and Management of Tardive Dyskinesia in Southeast Asia. 通过区域视角丰富全球视野：东南亚迟发性运动障碍的识别、评估和管理。
IF 2.8 4区 医学
Journal of Movement Disorders Pub Date : 2025-09-11 DOI: 10.14802/jmd.25146
Roongroj Bhidayasiri, Jin Kiat Ang, Kok Yoon Chee, Roger Ho, Ahmad Shahir Bin Mawardi, Adhi Wibowo Nurhidayat, Pongsatorn Paholpak, Pornjira Pariwatcharakul, Thitima Sanguanvichaikul, Eng Khean Ung, Natalia Dewi Wardani, Brian Yeo
{"title":"Enriching global perspectives through a regional lens: Recognition, Assessment, and Management of Tardive Dyskinesia in Southeast Asia.","authors":"Roongroj Bhidayasiri, Jin Kiat Ang, Kok Yoon Chee, Roger Ho, Ahmad Shahir Bin Mawardi, Adhi Wibowo Nurhidayat, Pongsatorn Paholpak, Pornjira Pariwatcharakul, Thitima Sanguanvichaikul, Eng Khean Ung, Natalia Dewi Wardani, Brian Yeo","doi":"10.14802/jmd.25146","DOIUrl":"https://doi.org/10.14802/jmd.25146","url":null,"abstract":"","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Writer's cramp, a task-specific focal hand dystonia, is treatable with dopaminergic modulation targeting striatal striosomes: a case report. Writer's抽筋，一种任务特异性局灶性手肌张力障碍，可通过针对纹状体纹状体的多巴胺能调节治疗：一个病例报告。
IF 2.8 4区 医学
Journal of Movement Disorders Pub Date : 2025-09-11 DOI: 10.14802/jmd.25177
Nobuhiro Inoue, Satoshi Goto
{"title":"Writer's cramp, a task-specific focal hand dystonia, is treatable with dopaminergic modulation targeting striatal striosomes: a case report.","authors":"Nobuhiro Inoue, Satoshi Goto","doi":"10.14802/jmd.25177","DOIUrl":"https://doi.org/10.14802/jmd.25177","url":null,"abstract":"","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uncommon Presentation of Subacute Sclerosing Panencephalitis: Two Cases of Rapidly Progressive Parkinsonism. 亚急性硬化性全脑炎的罕见表现：两例快速进行性帕金森病。
IF 2.8 4区 医学
Journal of Movement Disorders Pub Date : 2025-09-11 DOI: 10.14802/jmd.25185
Derencan Ateş, Bedia Samanci, Gözde Baran, Erdi Şahin, İbrahim Hakan Gürvit, Başar Bilgiç, Ferda İlgen Uslu, Ayşe Deniz Elmalı, Nerses Bebek, Yüksel Erdal, Haşmet Ayhan Hanağası
{"title":"Uncommon Presentation of Subacute Sclerosing Panencephalitis: Two Cases of Rapidly Progressive Parkinsonism.","authors":"Derencan Ateş, Bedia Samanci, Gözde Baran, Erdi Şahin, İbrahim Hakan Gürvit, Başar Bilgiç, Ferda İlgen Uslu, Ayşe Deniz Elmalı, Nerses Bebek, Yüksel Erdal, Haşmet Ayhan Hanağası","doi":"10.14802/jmd.25185","DOIUrl":"https://doi.org/10.14802/jmd.25185","url":null,"abstract":"","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgico-genomics in genetic Parkinson's disease: A single centre experience from a tertiary care centre. 遗传帕金森病的外科基因组学：来自三级保健中心的单中心经验。
IF 2.8 4区 医学
Journal of Movement Disorders Pub Date : 2025-09-11 DOI: 10.14802/jmd.25095
Debjyoti Dhar, Vikram V Holla, Sneha D Kamath, Nitish Kamble, Dwarakanath Srinivas, Ravi Yadav, Pramod Kumar Pal
{"title":"Surgico-genomics in genetic Parkinson's disease: A single centre experience from a tertiary care centre.","authors":"Debjyoti Dhar, Vikram V Holla, Sneha D Kamath, Nitish Kamble, Dwarakanath Srinivas, Ravi Yadav, Pramod Kumar Pal","doi":"10.14802/jmd.25095","DOIUrl":"https://doi.org/10.14802/jmd.25095","url":null,"abstract":"","PeriodicalId":16372,"journal":{"name":"Journal of Movement Disorders","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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