Journal of Pediatrics: X最新文献

{"title":"Giant Juvenile Xanthogranuloma Co-Occurring with Langerhans Cell Histiocytosis","authors":"Hiroshi Hayashi MD, Atsushi Makimoto MD, PhD, Kentaro Matsuoka MD, PhD","doi":"10.1016/j.ympdx.2023.100093","DOIUrl":"10.1016/j.ympdx.2023.100093","url":null,"abstract":"","PeriodicalId":36706,"journal":{"name":"Journal of Pediatrics: X","volume":"10 ","pages":"Article 100093"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590042023000095/pdfft?md5=999f529a79d000a57ee982c0ddfc7361&pid=1-s2.0-S2590042023000095-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45240286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of High Versus Low-Performing Hospitals for Very Preterm Infant Morbidity and Mortality","authors":"Shoshanna Sofaer DrPH ,&nbsp;Kimberly B. Glazer PhD, MPH ,&nbsp;Amy Balbierz MPH ,&nbsp;Anna Kheyfets BA ,&nbsp;Jennifer Zeitlin ScD ,&nbsp;Elizabeth A. Howell MD, MPP","doi":"10.1016/j.ympdx.2023.100094","DOIUrl":"https://doi.org/10.1016/j.ympdx.2023.100094","url":null,"abstract":"<div><h3>Objective</h3><p>To ascertain organizational attributes, policies, and practices that differentiate hospitals with high versus low risk-adjusted rates of very preterm neonatal morbidity and mortality (NMM).</p></div><div><h3>Methods</h3><p>Using a positive deviance research framework, we conducted qualitative interviews of hospital leadership and frontline clinicians from September-October 2018 in 4 high-performing and 4 low-performing hospitals in New York City, based on NMM measured in previous research. Key interview topics included NICU physician and nurse staffing, professional development, standardization of care, quality measurement and improvement, and efforts to measure and report on racial/ethnic disparities in care and outcomes for very preterm infants. Interviews were audiotaped, professionally transcribed, and coded using NVivo software. In qualitative content analysis, researchers blinded to hospital performance identified emergent themes, highlighted illustrative quotes, and drew qualitative comparisons between hospital clusters.</p></div><div><h3>Results</h3><p>The following features distinguished high-performing facilities: 1) stronger commitment from hospital leadership to diversity, quality, and equity; 2) better access to specialist physicians and experienced nursing staff; 3) inclusion of nurses in developing clinical policies and protocols, and 4) acknowledgement of the influence of racism and bias in healthcare on racial-ethnic disparities. In both clusters, areas for improvement included comprehensive family engagement strategies, care standardization, and reporting of quality data by patient sociodemographic characteristics.</p></div><div><h3>Conclusions and relevance</h3><p>Our findings suggest specific organizational and cultural characteristics, from hospital leadership and clinician perspectives, that may yield better patient outcomes, and demonstrate the utility of a positive deviance framework to center equity in quality initiatives for high-risk infant care.</p></div>","PeriodicalId":36706,"journal":{"name":"Journal of Pediatrics: X","volume":"10 ","pages":"Article 100094"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590042023000101/pdfft?md5=cb669e6535d708b670963869b96c7777&pid=1-s2.0-S2590042023000101-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138633629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tracking of Cardiorespiratory Fitness and Physical Activity from Youth to Young Adulthood: Findings from the Prospective Special Turku Coronary Risk Factor Intervention Project (STRIP)","authors":"Brooklyn J. Fraser PhD ,&nbsp;Leigh Blizzard PhD ,&nbsp;Suvi P. Rovio PhD ,&nbsp;Olli J. Heinonen MD, PhD ,&nbsp;Harri Niinikoski MD, PhD ,&nbsp;Jorma S.A. Viikari MD, PhD ,&nbsp;Tapani Rönnemaa MD, PhD ,&nbsp;Antti Jula MD, PhD ,&nbsp;Olli T. Raitakari MD, PhD ,&nbsp;Costan G. Magnussen PhD ,&nbsp;Katja Pahkala PhD","doi":"10.1016/j.ympdx.2023.100085","DOIUrl":"10.1016/j.ympdx.2023.100085","url":null,"abstract":"<div><p>Using data from the Special Turku Coronary Risk Factor Intervention Project, cardiorespiratory fitness (rank-order correlation coefficient = 0.60-0.62) tracked stronger than physical activity (rank-order correlation coefficient = 0.27-0.38) between youth (age = 17 years) and young adulthood (age = 26 years). Cardiorespiratory fitness could help identify individuals at risk of maintaining poor fitness levels or developing adverse health in adulthood.</p></div>","PeriodicalId":36706,"journal":{"name":"Journal of Pediatrics: X","volume":"9 ","pages":"Article 100085"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4e/33/main.PMC10258116.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9661525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors and Clinical Correlates of Pediatric Serotonin Syndrome in Hospitalized Suicide Attempters","authors":"Susheel K. Khetarpal MD, MS ,&nbsp;Manivel Rengasamy MD ,&nbsp;Ololade Adebiyi MD ,&nbsp;Kimberly Hsiung MD, MS ,&nbsp;Sammi Wong BS ,&nbsp;Joshua Shulman MD ,&nbsp;Anthony Pizon MD","doi":"10.1016/j.ympdx.2023.100086","DOIUrl":"10.1016/j.ympdx.2023.100086","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the risk factors and clinical correlates of pediatric serotonin syndrome (SS) given that research on SS in adults exists, there is a dearth of literature on pediatric SS.</p></div><div><h3>Study design</h3><p>We conducted a retrospective chart review of 183 pediatric patients who were medically hospitalized after a suicide attempt. We investigated associations between SS and several of its risk factors and clinical correlates. We also assessed the sensitivity/specificity of Hunter’s criteria and criterion symptoms in predicting SS.</p></div><div><h3>Results</h3><p>SS occurred in 21.7% of patients with a serotonergic overdose. Recent marijuana use and overdose on a selective serotonin reuptake inhibitor were significantly associated with SS. Individuals with SS required a greater number of days to be medically stabilized and had a greater likelihood of being placed on a ventilator during treatment. Hunter’s criteria had 66.7% sensitivity and 92.3% specificity in diagnosing SS.</p></div><div><h3>Conclusions</h3><p>Our study reveals both novel risk factors associated with SS (eg, recent marijuana use) and clinical correlates for patients with pediatric SS. In children, Hunter’s criteria appeared to have good specificity but poor sensitivity in identifying SS. Our results set the stage for future work aimed at enhancing clinicians’ ability to more rapidly identify and treat pediatric SS.</p></div>","PeriodicalId":36706,"journal":{"name":"Journal of Pediatrics: X","volume":"9 ","pages":"Article 100086"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/dd/main.PMC10258115.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9654905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"General Movement Assessment in Babies Born Preterm: Motor Optimality Score–Revised (MOS-R), Trajectory, and Neurodevelopmental Outcomes at 1 Year","authors":"Archana S. Kadam MD, DNB ,&nbsp;Sidharth A. Nayyar DNB ,&nbsp;Sandeep S. Kadam DM, MD ,&nbsp;Bindu C. Patni MA (Clinical Psychology), Dip. CP ,&nbsp;Madhura C. Khole B.P.th ,&nbsp;Anand N. Pandit MD, FRCPCH ,&nbsp;Nandkishor S. Kabra DM MD, MSc (Clinical Epidemiology)","doi":"10.1016/j.ympdx.2022.100084","DOIUrl":"10.1016/j.ympdx.2022.100084","url":null,"abstract":"<div><h3>Objective</h3><p>To assess the association between the General Movement Assessment (GMA) findings, including Motor Optimality Scores–Revised (MOS-R) at 16 weeks, and neuromotor outcome assessed by the Amiel-Tison Neurological Assessment at 9 months of corrected age and the Developmental Assessment Scales for Indian Infants (DASII) at 1 year of corrected age in preterm ≤32 weeks.</p></div><div><h3>Study design</h3><p>Serial GMA videos of infants born preterm ≤32 weeks were recorded on day 7, 35 weeks of postmenstrual age, 40 weeks of postmenstrual age, and 16 weeks of corrected age. The association between GMA findings, including MOS-R scores and GM trajectory between 35 to 40 weeks and the Amiel-Tison Neurological Assessment and DASII scores, was assessed by Spearman correlation, Fisher exact tests, and ordinal regression.</p></div><div><h3>Results</h3><p>Moderate correlations were observed between MOS-R and the DASII motor DQ (Spearman r = 0.70, <em>P</em> &lt; .001) and between MOS-R and DASII Mental DQ (r = 0.65, <em>P</em> &lt; .001). The GMA trajectory at 35-40 weeks was associated with DASII motor DQ (Fisher exact, <em>P</em> = .002), and also with the Amiel-Tison Neurological Assessment at 9 months of corrected age (<em>P</em> &lt; .01 by the Fisher exact test). On analysis by performing ordinal regression of predictive values of the general movements (GM) at 7 days of age, GM at 35 weeks, GM at 40 weeks, GM at 16 weeks, and MOS-R at 16 weeks, MOS-R alone was a statistically significant predictor of motor DQ at 1 year of age (OR −0.59; 95% CI −0.97 to −0.22; Wald statistics, <em>P</em> &lt; .02).</p></div><div><h3>Conclusions</h3><p>Consistent with findings in high-income countries, GMA including MOS-R scores performed in Indian infants born preterm during the neonatal period and early infancy is associated with neurodevelopmental outcomes in the first year of life. GMA can help initiate focused early intervention in low- and middle-income settings, where resources may be limited.</p></div>","PeriodicalId":36706,"journal":{"name":"Journal of Pediatrics: X","volume":"8 ","pages":"Article 100084"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/ac/main.PMC10236536.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9663730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthy-Weight Kindergarten Children with Autism Spectrum Disorder May Become Overweight and Obese during the First Few Years of Elementary School","authors":"Misha Eliasziw PhD ,&nbsp;Tanja V.E. Kral PhD ,&nbsp;Mary Segal PhD ,&nbsp;Linmarie Sikich MD ,&nbsp;Sarah Phillips MS, MPH ,&nbsp;David J. Tybor PhD ,&nbsp;Linda G. Bandini PhD ,&nbsp;Carol Curtin PhD ,&nbsp;Aviva Must PhD","doi":"10.1016/j.ympdx.2021.100074","DOIUrl":"10.1016/j.ympdx.2021.100074","url":null,"abstract":"<div><p>Analysis of a population-based, nationally-representative longitudinal sample from the Early Childhood Longitudinal Study, Kindergarten Class of 2010-11 identified an increase in healthy-weight children with autism spectrum disorder becoming overweight and obese between first and second grade, thus identifying a critical period for early prevention and treatment.</p></div>","PeriodicalId":36706,"journal":{"name":"Journal of Pediatrics: X","volume":"7 ","pages":"Article 100074"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/33/14/main.PMC10236540.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9716810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Info For Authors","authors":"","doi":"10.1016/S2590-0420(21)00016-1","DOIUrl":"https://doi.org/10.1016/S2590-0420(21)00016-1","url":null,"abstract":"","PeriodicalId":36706,"journal":{"name":"Journal of Pediatrics: X","volume":"7 ","pages":"Article 100079"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590042021000161/pdfft?md5=f01f3619d845abbb63f0de9d17ec6f74&pid=1-s2.0-S2590042021000161-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71853011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonatal Outcomes in the MONEAD Study of Pregnant Women with Epilepsy","authors":"Linda J. Van Marter MD, MPH ,&nbsp;Page B. Pennell MD ,&nbsp;Carrie Brown MS ,&nbsp;Adam L. Hartman MD ,&nbsp;Ryan C. May PhD ,&nbsp;Thomas McElrath MD, PhD ,&nbsp;Dominic Ippolito MS ,&nbsp;Kimford J. Meador MD","doi":"10.1016/j.ympdx.2021.100073","DOIUrl":"10.1016/j.ympdx.2021.100073","url":null,"abstract":"<div><h3>Objective</h3><p>To determine whether growth measures at birth differ between offspring of pregnant women with epilepsy and healthy pregnant women.</p></div><div><h3>Study design</h3><p>The Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study is a National Institutes of Health–funded, prospective, observational, multicenter investigation of pregnancy outcomes for mothers and their infants. Between 2012 and 2016, pregnant women with epilepsy and healthy pregnant women were enrolled at 20 US epilepsy centers. Pregnant women with epilepsy were exposed to various antiepileptic drugs. The main outcome measure was small for gestational age at birth. Principal univariate and multivariate analyses compared outcomes between pregnant women with epilepsy and healthy pregnant women. Secondary analyses focused on outcomes among mothers receiving different antiepileptic drug therapies.</p></div><div><h3>Results</h3><p>In total, 345 infants were born to 331 pregnant women with epilepsy and 106 infants were born to 102 healthy pregnant women. No differences were seen between infants born to pregnant women with epilepsy vs healthy pregnant women in preterm births, major congenital malformations, 5-minute Apgar &lt;6, special care nursery or neonatal intensive care unit admission, gestational age, or any growth measure. There was no difference in the rates of small for gestational age status among infants born to pregnant women with epilepsy vs healthy pregnant women; however, infants born to mothers receiving topiramate had lower birth weight z scores and lamotrigine higher birth weight z scores compared with other monotherapies. The greatest rate of special care nursery or neonatal intensive care unit admission was observed among those on oxcarbazepine monotherapy.</p></div><div><h3>Conclusions</h3><p>Maternal treatment with antiepileptic drugs, overall, appears unassociated with adverse early neonatal outcomes. However, specific monotherapies appear to affect fetal growth with, on average, the greatest reduction in birth weight z score observed among infants born to pregnant women with epilepsy exposed to topiramate monotherapy.</p></div><div><h3>Trial registration</h3><p><span>ClinicalTrials.gov</span><svg><path></path></svg><span>NCT01730170</span><svg><path></path></svg></p></div>","PeriodicalId":36706,"journal":{"name":"Journal of Pediatrics: X","volume":"7 ","pages":"Article 100073"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ympdx.2021.100073","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9623184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-Year Changes in Low-Income Children's Physical Activity: Prospective Influence of Neighborhood Environment and Parent Supportive Behavior","authors":"Simone A. French PhD ,&nbsp;Yingling Fan PhD ,&nbsp;Alicia S. Kunin-Batson PhD ,&nbsp;Jerica M. Berge PhD, MPH, LMFT ,&nbsp;Nidhi Kohli PhD ,&nbsp;Rik Z. Lamm BS ,&nbsp;Nancy E. Sherwood PhD","doi":"10.1016/j.ympdx.2021.100066","DOIUrl":"10.1016/j.ympdx.2021.100066","url":null,"abstract":"<div><h3>Objectives</h3><p>To prospectively evaluate parent supportive behaviors (PSB) for child physical activity (PA) and neighborhood environment variables on changes in child PA over 3 years.</p></div><div><h3>Study design</h3><p>Secondary data analysis of the Now Everybody Together for Amazing and Healthful Kids-Works study with 534 parent-child (age 2-4 years) dyads randomized to a community-based pediatric obesity prevention intervention for 3 years (92% retention). PSB and neighborhood environmental variables were examined in relation to changes in child moderate-to-vigorous PA (MVPA), light and sedentary activity, and screen time. Child and parent accelerometry data were collected at visit 0, 12, 24, and 36 months. Mixed multivariate models were used to examine independent and interactive effects of parent-level and neighborhood-level variables on changes in child PA outcomes.</p></div><div><h3>Results</h3><p>PSB significantly interacted with visit on change in child MVPA (β = 0.12) and sedentary behaviors (β = -0.18). Over 3 years, a 1-unit increase in PSB was associated with an average increase of 4.3 minutes/day of MVPA and an average decrease of 6.5 minutes/day of sedentary time. Significant main effects were observed for PSB and 3-year change in child screen time (β = -0.05). The children of parents with higher PSB at baseline watched an average of 1.8 fewer minutes/day of screen time compared with parents with lower baseline PSB. Neighborhood-level variables were not significantly associated with changes in child PA outcomes.</p></div><div><h3>Conclusions</h3><p>Parents who increase their supportive behaviors for their child's PA have children who are more physically active and less sedentary over time. Interventions to increase preschool-age children's PA may enhance their effectiveness by targeting parents' supportive behaviors for their child's PA.</p></div>","PeriodicalId":36706,"journal":{"name":"Journal of Pediatrics: X","volume":"6 ","pages":"Article 100066"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ympdx.2021.100066","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9662429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antenatal and Postnatal Maternal Depressive Symptoms and Trajectories and Child Hospitalization up to 24 Months of Life: Findings From the 2015 Pelotas (Brazil) Birth Cohort Study","authors":"Nadège Jacques PhD ,&nbsp;Marilia Arndt Mesenburg PhD ,&nbsp;Joseph Murray PhD ,&nbsp;Andréa Dâmaso Bertoldi PhD ,&nbsp;Marlos Rodrigues Domingues PhD ,&nbsp;Alan Stein FRCPsych ,&nbsp;Mariangela Freitas Silveira MD, PhD","doi":"10.1016/j.ympdx.2021.100065","DOIUrl":"10.1016/j.ympdx.2021.100065","url":null,"abstract":"<div><h3>Objective</h3><p>To examine the association between antenatal and postnatal maternal depression symptoms, and child hospitalization during the first 2 years of life in the 2015 Pelotas Birth Cohort Study.</p></div><div><h3>Study design</h3><p>This is an observational study. Maternal depressive symptoms of 4275 mothers were measured using the Edinburgh Postnatal Depression Scale. Hospitalization of the child for any reason was assessed using maternal report. Bivariate analysis and multivariate Poisson regressions were used to assess the association between maternal depressive symptoms and child hospitalization.</p></div><div><h3>Results</h3><p>Compared with children of mothers with low depressive symptoms, children whose mothers experienced significant antenatal depressive symptoms were 1.74 (95% CI, 1.16-2.60) times more likely to be hospitalized by 3 months of age, and 2.14 (95% CI, 1.46-3.14) times more likely up to 24 months. For children whose mothers experienced severe postnatal depressive symptoms at 3 months, the risks for hospitalization by age 12 months were 1.84 (95% CI, 1.39-2.45) higher than children whose mothers had low depressive symptoms. There was an increased risk of hospitalization for children according to the severity of depressive trajectories across time.</p></div><div><h3>Conclusions</h3><p>Maternal depressive symptoms are a risk factor for hospitalization in children up to 2 years of age, and this risk increases with increased severity of depression. These results have public health relevance for decreasing the risk factors in mothers that can lead to hospitalization in children.</p></div>","PeriodicalId":36706,"journal":{"name":"Journal of Pediatrics: X","volume":"6 ","pages":"Article 100065"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ympdx.2021.100065","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9643266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}