Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference最新文献_第6页

Gait analysis of diabetic foot 糖尿病足的步态分析

Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514477

H. Ranu

引用次数: 6

Orthopaedic alloy electrochemical behavior: the case of Ti-6Al-7Nb 矫形合金电化学行为:以Ti-6Al-7Nb为例

Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514488

G. Lewis, K. M. Shaw

引用次数: 2

The effect of P-Trp, P-Ala and P-Val on the proliferation rate of HeLa cells in culture P-Trp、P-Ala和P-Val对HeLa细胞增殖率的影响

Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514505

H. Benghuzzi, M. Tucci

{"title":"The effect of P-Trp, P-Ala and P-Val on the proliferation rate of HeLa cells in culture","authors":"H. Benghuzzi, M. Tucci","doi":"10.1109/SBEC.1995.514505","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514505","url":null,"abstract":"The objective of this study was to investigate the effect of various biomedical polymers on the adhesion rate of HeLa cells as a model. The HeLa cells used in this study seeded by following our standard laboratory procedure. A total of 1/spl times/10/sup 5/ cells were plated in each of the pretreated wells with various concentrations of (0.01, 0.1, and 1% wt/vol) polyvaline (P-Val), polyalanine (p-Ala), polytryptophan (P-Trp) and buffered control. At the end of 1,4, and 24 hours the assay was developed by following standard lab procedure. The final determination was achieved by means of ELIZA. The data obtained from this study suggest that (i) the rate of HeLa spreading was strongly influenced by both incubation time and the polymer concentration, (ii) it is apparent that polymer treated wells within the first hour facilitated attachment of HeLa cells to their surfaces for all concentrations tested with the exception of 1% alanine. This observation confirms our previous results using different cell lines and provides a valuable information for experiments that need to be performed in a short period of time with the maximum amount of cells attached, (iii) the surface attachment of HeLa to P-Ala, P-Val, and P-Trp were demonstrated to vary depending on their chemical structure and level of microporosity. Thus, overall observation led us to conclude that the surface reactivity of P-Ala, P-Val, and P-Trp be always taken into account in discussing their biocompatibility using transformed cells such as HeLa cells as a model.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128449415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Healon, N,O carboxymethyl Chitosan and Vitreon on conjunctival cells and human peripheral blood lymphocytes Healon、N、O羧甲基壳聚糖和玻璃体对结膜细胞和人外周血淋巴细胞的影响

Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514503

M. Langford, J. Schulman, D. P. Mukherjee, J. Ganley

{"title":"Effects of Healon, N,O carboxymethyl Chitosan and Vitreon on conjunctival cells and human peripheral blood lymphocytes","authors":"M. Langford, J. Schulman, D. P. Mukherjee, J. Ganley","doi":"10.1109/SBEC.1995.514503","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514503","url":null,"abstract":"Hyaluronic acid (HA) and perfluorocarbon liquid (PFCL) are used during and after intraocular surgery to maintain normal ocular structure. We present the results of our studies on the effects of vertebrate HA (Healon), N,O carboxymethyl Chitosan (CMC), and PFCL (perfluorophenanthrene, Vitreon) on conjunctival epithelial cells and human peripheral blood leukocytes (PBL). No cytotoxic effects were observed with HA or CMC on conjunctival epithelial cells. PFCL flattened cultured conjunctival cells and was cytocidal. CMC was associated with the formation of monocyte/macrophage syncytia in mitogen stimulated PBL cultures. CMC and PFCL inhibited PBL proliferation and interferon-/spl gamma/ (IFN-/spl gamma/) production by phytohemagglutinin (PHA), concanavalin A (ConA) and Staphylococcal enterotoxin B (SEB) stimulated PBL. Our results indicate that HA and CMC are not toxic to conjunctival epithelial cells but suggest that CMC may affect monocyte/macrophage functions associated with T cell proliferation and IFN-/spl gamma/ production. PFCL is cytocidal to conjunctival epithelial cells in stationary cultures and suppresses PBL proliferation and IFN-/spl gamma/ production.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134351970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Numerical simulations of flow in flared sections of the human infrarenal aorta 人肾下主动脉张开段血流的数值模拟

Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514423

N. Mapara, N. F. MacLean, D. Steinman, D. Holdsworth, M. R. Roach

{"title":"Numerical simulations of flow in flared sections of the human infrarenal aorta","authors":"N. Mapara, N. F. MacLean, D. Steinman, D. Holdsworth, M. R. Roach","doi":"10.1109/SBEC.1995.514423","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514423","url":null,"abstract":"The formation of separation zones in arteries may have important implications in the development of atherosclerotic lesions. It is known that arteries flare proximally to bifurcations where atherosclerotic lesions develop. Flow through an axisymmetric flared cylinder, which simulated the human infrarenal aorta, was studied using FIDAP, a finite element analysis program. Blood was assumed to have Newtonian properties while the flow was assumed to be steady and laminar. The wall of the artery was considered to be rigid. For this study, the angle of flare was varied from 1/spl deg/ to 5/spl deg/ with an inlet to outlet diameter ratio of 0.33. Reynolds numbers for the simulation ranged from 100 to 1000. A critical Reynolds number existed below which no separation zone was formed. At Reynolds numbers greater than this critical value, recirculation zones formed downstream of the flare. A linear relationship was observed between the length of the recirculation zone and the Reynolds number. There was an inverse, non-linear relationship between the critical Reynolds number and the flaring angle. The length of the recirculation zone was more sensitive to changes in Reynolds numbers at higher flaring angles.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134399292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A biomechanical evaluation of metacarpal fracture fixation with absorbable polyglycolide rods 可吸收性聚乙醇棒固定掌骨骨折的生物力学评价

Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514492

T. Maruyama, Subrata Saha, D. Mongiano, K. Mudge

引用次数: 1

A biomechanical study of mandibular fracture fixation plates in a bovine rib model 牛肋骨模型下颌骨骨折固定钢板的生物力学研究

Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514441

K. Coward, B. Smith, R. N. Kruse, D. P. Mukherjee

引用次数: 2

Three dimensional modeling and analysis of Haversian systems in compact bone tissue 致密骨组织中哈弗氏系统的三维建模与分析

Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514450

K. Deisseroth, H. Hogan

引用次数: 0

Advances in laser technology assist in treatment for retinopathy of prematurity 激光技术的进步有助于早产儿视网膜病变的治疗

Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514456

L. Kooragayala, J. Schulman, A. Pramanik, P. Tseng

{"title":"Advances in laser technology assist in treatment for retinopathy of prematurity","authors":"L. Kooragayala, J. Schulman, A. Pramanik, P. Tseng","doi":"10.1109/SBEC.1995.514456","DOIUrl":"https://doi.org/10.1109/SBEC.1995.514456","url":null,"abstract":"Cryotherapy is the accepted method to treat retinopathy of prematurity (ROP). The Cryotherapy for Retinopathy of Prematurity Cooperative Group conducted a prospective randomized study which established the beneficial effectiveness of cryopexy as a treatment modality for threshold ROP. Despite demonstrating the overall beneficial effects of cryotherapy, a small subgroup of infants in the study with zone-I threshold ROP showed either no beneficial effects or at most a minimal reduction in unfavorable events in eyes treated with cryotherapy. The failure rate was reduced from 91.77% to 75% when comparing control to treated eyes although only twelve eyes were treated. Based on these poor treatment results and significant advances in laser technology a renewed interest has developed in the use of laser photocoagulation to treat eyes with zone I threshold ROP. Delivery of thermal laser spots to the retinal periphery has been simplified following development of an indirect laser delivery system. Additional interest has been stimulated by the recent commercial availability of the compact solid state diode lasers. This laser, unlike older gas ion lasers has a lower cost, does not require any ancillary cooling, operates on standard voltage requirements and in some instances is capable of being driven by batteries. A diode laser as a result can easily transported to, and operated in, the neonatal intensive care unit. The authors present the results of a prospective study evaluating diode laser photocoagulation in the management of 23 consecutive premature infant eyes with zone I threshold ROP. The mean follow-up was 53.6 weeks. A favorable outcome was achieved in 22 of the 23 eyes. Various features of the diode laser which appeared to significantly contribute to these improved treatment results are discussed.","PeriodicalId":332563,"journal":{"name":"Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference","volume":"10880 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133770648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthetic polymers as carriers for osteogenic proteins 合成聚合物作为成骨蛋白的载体

Proceedings of the 1995 Fourteenth Southern Biomedical Engineering Conference Pub Date : 1995-04-07 DOI: 10.1109/SBEC.1995.514454

S. Salkeld, S. Cook, D. Rueger

引用次数: 3