{"title":"THE EFFECT OF VARIOUS MOLOTOV COCKTAILS ON DIFFERENT SURFACES AND EVALUATION OF FIRE CHANGES","authors":"Zeliha Yıldırım, Cem Uysal","doi":"10.56484/iamr.1439171","DOIUrl":"https://doi.org/10.56484/iamr.1439171","url":null,"abstract":"Objective:Molotov cocktails are a classic homemade weapon used over the past 80 years; also known as gasoline bombs. However, there is not enough research in the literature. Molotov cocktail is classified as a mildly explosive substance. But a Molotov cocktail is not an explosive. This is a handmade lighter. It is used to set fire to targets in terrorist attacks. \u0000Methods:In our study, classic homemade Molotov cocktails were used. Oil, diluent, sugar, cologne, epoxy resin, paraffin, egg white, liquid and solid detergent, bleach, wood glue were added to the mixture. Parameters such as burning temperature, burning time, glass and nail spreading diameter, and residues of the Molotov cocktail were investigated. The prepared molotov cocktails were broken on 5 different floors, and the effect of changing the floor on the parameters was investigated. \u0000Results:In our study, 51 (59.3%) of 86 molotov cocktails were broken. Most of the destruction occurred in the wall. According to the results we obtained, a relationship was found between the content of the Molotov cocktail, the burning temperature and the time. It was found that the damage was increased with the addition of substances to the mixture. \u0000Conclusion: In addition, in our study, it was noticed that the Molotov cocktail did not explode by itself and did not cause damage to the environment by throwing nails.","PeriodicalId":479189,"journal":{"name":"International Archives of Medical Research","volume":" 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141824630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Which one is more dangerous in childhood Rotavirus or Adenovirus?","authors":"H. Onur, Arzu Rahmanalı Onur","doi":"10.56484/iamr.1459778","DOIUrl":"https://doi.org/10.56484/iamr.1459778","url":null,"abstract":"Objective: Determination of the frequency of Rotavirus and Adenovirus in patients diagnosed with gastroenteritis in the Pediatric Polyclinic of our hospital by immunochromatographic method and retrospective evaluation of the change in the distribution of the agent according to age, gender and vaccination status. \u0000Method: Those patients with complaints of diarrhea, vomiting, dehydration, and fever as well as those diagnosed with acute gastroenteritis were evaluated by taking fresh stool samples between January 2015 and November 2020. The data were presented using descriptive statistics. \u0000Results: The number of acute gastroenteritis patients included in the study was 1,192. The mean age of the patients was 18±SD months (min: 1 month, max: 180 months). Adenovirus and Rotavirus antigens were detected in 10% of all cases (n=119). Rotavirus antigen was positive in 6.6% (n=78) and Adenovirus antigen was positive in 3.1% (n=38) of all cases. The hospitalization rate was 5.1 times higher in Rotavirus positive cases (p","PeriodicalId":479189,"journal":{"name":"International Archives of Medical Research","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141832427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long Non-Coding RNA H19 Expression in Leukemia Patients","authors":"Kadir Sinan ASLAN, Sema AGÜLOĞLU FİNCAN","doi":"10.56484/iamr.1350443","DOIUrl":"https://doi.org/10.56484/iamr.1350443","url":null,"abstract":"Abstract
 Objective: BCR-ABL fusion gene occurs with the formation of translocations in the t(9;22) region of the Philadelphia (Ph) chromosome, which is used as a diagnostic biomarker in Chronic Myeloid Leukemia (CML). These abnormal genetic changes, which cover 15% of leukemias, reach dimensions that threaten human life. Recent studies have determined that thousands of genes expressed in differentiation and development processes contain non-protein-coding RNA with a regulatory role. Of these, the first discovered long noncoding RNA (LncRNA) H19 has been associated with its biological role, cell proliferation, apoptosis and metastasis Therefore, studies have been conducted considering that LncRNA H19 can be used as a biological marker in CML patients.
 Method: For this study, blood from 72 CML patients over 18 years of age and 64 healthy individuals were used. After RNA isolation of each of these bloods and cDNAs were obtained, the expression levels of the LncRNA H19 gene were analyzed by Real Time PCR method.
 Results: As a result of the expression study, it was found that LncRNA H19 gene expression increased 4.37 times and was upregulated in Bcr-Abl positive patients (p=0.414683). 
 Conclusion: In this study conducted in Diyarbakır region, we think that LncRNA H19, which is up-regulated in terms of CML profiles, can be used as a biological marker for new treatment applications.","PeriodicalId":479189,"journal":{"name":"International Archives of Medical Research","volume":"212 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135943301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determination of Antibacterial Efficacy of Lactoferrin Glycoprotein Obtained from Cow Colostrum","authors":"İlhan SABANCILAR, Gülten TOPRAK, Hakan TEMİZ","doi":"10.56484/iamr.1326284","DOIUrl":"https://doi.org/10.56484/iamr.1326284","url":null,"abstract":"Objective: It was aimed to investigate the antibacterial effect levels of Lactoferrin protein in cow colostrum. The aim of the study was to evaluate the effect of lactoferrin protein obtained from a natural product on the growth of Escherichia coli, Pseudomonas aerugenosa and Staphylococcus aureus.
 Method: Lactoferrin at 4 different concentrations (100 mg/ml, 50 mg/ml, 25mg/ml and 12.5mg/ml) was impregnated on 6 mm discs prepared from filter paper and placed on the MHA plate and after incubation at 37˚C for 24 hours, inhibition was evaluated. The antibacterial effect levels of naturally obtained lactoferrin at different concentrations were compared.
 Results: It was determined that the antibacterial activity of lactoferrin against Gram-negative bacteria Pseudomonas aeruginosa was higher than the other bacterial species in the study. It was determined that Lactoferrin at a concentration of 12.5mg/ml had the least inhibitory effect in the studied bacteria. It was concluded that E.coli and S. aureus were bacteria resistant to the antibacterial activity of lactoferrin.
 Conclusion: It was observed that this effect was limited in E.coli bacteria. In the light of these results, it was concluded that Lactoferrin, an antibacterial agent, has different antibacterial effects depending on the bacterial species and dose.","PeriodicalId":479189,"journal":{"name":"International Archives of Medical Research","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135943300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}